{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T00:01:20Z","timestamp":1769817680661,"version":"3.49.0"},"publisher-location":"Cham","reference-count":47,"publisher":"Springer International Publishing","isbn-type":[{"value":"9783319695440","type":"print"},{"value":"9783319695457","type":"electronic"}],"license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017]]},"DOI":"10.1007\/5584_2017_37","type":"book-chapter","created":{"date-parts":[[2017,6,1]],"date-time":"2017-06-01T14:39:59Z","timestamp":1496327999000},"page":"35-43","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Lung Lesions During Fever of Unknown Origin"],"prefix":"10.1007","author":[{"given":"Renata","family":"Krupa","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tadeusz M.","family":"Zielonka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Malgorzata","family":"Hadzik-Blaszczyk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazimierz A.","family":"Wardyn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katarzyna","family":"Zycinska","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2017,6,2]]},"reference":[{"key":"37_CR1","doi-asserted-by":"publisher","first-page":"366","DOI":"10.1016\/S0039-6060(97)90305-6","volume":"121","author":"AF AbuRahma","year":"1997","unstructured":"AbuRahma AF, Saiedy S, Robinson PA, Boland JP, Cottrell DJ 4th, Stuart C (1997) Role of venous duplex imaging of the lower extremities in patients with fever of unknown origin. Surgery 121:366\u2013371","journal-title":"Surgery"},{"key":"37_CR2","doi-asserted-by":"publisher","first-page":"673","DOI":"10.1159\/000064068","volume":"92","author":"H Akar","year":"2002","unstructured":"Akar H, Ozbasli-Levi C, Senturuk T, Kadikoylu G, Levi E, Bolaman Z (2002) MPO-ANCA associated small vessel vasculitis presenting as fever of unknown origin. Report of one case. Nephron 92:673\u2013675","journal-title":"Nephron"},{"key":"37_CR3","first-page":"147","volume":"73","author":"J Altenburg","year":"2015","unstructured":"Altenburg J, Wortel K, van der Werf TS, Boersma WG (2015) Non-cystic fibrosis bronchiectasis: clinical presentation, diagnosis and treatment, illustrated by data from a Dutch Teaching Hospital. Neth J Med 73:147\u2013154","journal-title":"Neth J Med"},{"key":"37_CR4","doi-asserted-by":"publisher","first-page":"575","DOI":"10.1016\/S0140-6736(97)07061-X","volume":"350","author":"PM Arnow","year":"1997","unstructured":"Arnow PM, Flaherty JP (1997) Fever of unknown origin. Lancet 350:575\u2013580","journal-title":"Lancet"},{"key":"37_CR5","doi-asserted-by":"publisher","first-page":"646","DOI":"10.1164\/ajrccm.161.2.ats3-00","volume":"161","author":"ATS","year":"2000","unstructured":"ATS (2000) Idiopathic pulmonary fibrosis: diagnosis and treatment. International consensus statement. American Thoracic Society (ATS), and the European Respiratory Society (ERS). Am J Respir Crit Care Med 161:646\u2013664","journal-title":"Am J Respir Crit Care Med"},{"key":"37_CR6","first-page":"149","volume":"16","author":"ATS\/ERS\/WASOG","year":"1999","unstructured":"ATS\/ERS\/WASOG (1999) Statement on sarcoidosis. Sarcoidosis Vasc Diffuse Lung Dis 16:149\u2013173","journal-title":"Sarcoidosis Vasc Diffuse Lung Dis"},{"key":"37_CR7","doi-asserted-by":"crossref","first-page":"325","DOI":"10.5603\/ARM.34896","volume":"81","author":"E Augustynowicz-Kope\u0107","year":"2013","unstructured":"Augustynowicz-Kope\u0107 E, Demkow U, Grzelewska-Rzymowska I, Korzeniewska-Kose\u0142a M, Langfort R, Micha\u0142owska-Mitczuk D, Rowi\u0144ska-Zakrzewska E, Zielonka TM, Zio\u0142kowski J, Zwolska Z (2013) Guidelines of Polish Respiratory Society concerning diagnosis, treatment and prevention of tuberculosis in adults and in child. Pneumonol Alergol Pol 81:325\u2013379","journal-title":"Pneumonol Alergol Pol"},{"key":"37_CR8","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1016\/S0953-6205(03)00075-X","volume":"14","author":"C Baicus","year":"2003","unstructured":"Baicus C, Bolosiu HD, Tanasescu C, Baicus A (2003) Fever of unknown origin-predictors of outcome. A prospective multicenter study on 164 patients. Eur J Intern Med 14:249\u2013254","journal-title":"Eur J Intern Med"},{"key":"37_CR9","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1097\/MD.0b013e31802fe858","volume":"86","author":"CP Bleeker-Rovers","year":"2007","unstructured":"Bleeker-Rovers CP, Vos FJ, de Kleijn EM, Mudde AH, Dofferhoff TS, Richter C, Smilde TJ, Krabbe PF, Oyen WJ, van der Meer JW (2007) A prospective multicenter study on fever of unknown origin: the yield of a structured diagnostic protocol. Medicine (Baltimore) 86:26\u201338","journal-title":"Medicine (Baltimore)"},{"key":"37_CR10","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1513\/pats.200511-120JH","volume":"3","author":"KK Brown","year":"2006","unstructured":"Brown KK (2006) Pulmonary vasculitis. Proc Am Thorac Soc 3:48\u201357","journal-title":"Proc Am Thorac Soc"},{"key":"37_CR11","doi-asserted-by":"publisher","first-page":"1446","DOI":"10.1183\/09031936.00119114","volume":"45","author":"JD Chalmers","year":"2015","unstructured":"Chalmers JD, Aliberti S, Blasi F (2015) Management of bronchiectasis in adults. Eur Respir J 45:1446\u20131462","journal-title":"Eur Respir J"},{"key":"37_CR12","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1053\/sroe.2002.29585","volume":"37","author":"C Chiles","year":"2002","unstructured":"Chiles C (2002) Imaging features of thoracic sarcoidosis. Semin Roentgenol 37:82\u201393","journal-title":"Semin Roentgenol"},{"key":"37_CR13","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1016\/S0891-5520(05)70290-7","volume":"10","author":"BA Cunha","year":"1996","unstructured":"Cunha BA (1996) Fever of unknown origin. Infect Dis Clin N Am 10:111\u2013127","journal-title":"Infect Dis Clin N Am"},{"key":"37_CR14","doi-asserted-by":"publisher","first-page":"867","DOI":"10.1016\/j.idc.2007.09.002","volume":"21","author":"BA Cunha","year":"2007","unstructured":"Cunha BA (2007a) Fever of unknown origin. Clinical overview of classic and current concepts. Infect Dis Clin N Am 21:867\u2013915","journal-title":"Infect Dis Clin N Am"},{"key":"37_CR15","doi-asserted-by":"publisher","first-page":"27","DOI":"10.3109\/9781420019582.005","volume-title":"Fever of unknown origin","author":"BA Cunha","year":"2007","unstructured":"Cunha BA (2007b) Fever of unknown origin in malignancies. In: Cunha BA (ed) Fever of unknown origin. Informa Healthcare, New York, pp 27\u201334"},{"key":"37_CR16","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1016\/j.hrtlng.2005.03.010","volume":"35","author":"BA Cunha","year":"2006","unstructured":"Cunha BA, Parchuri S, Mohan S (2006) Fever of unknown origin: temporal arteritis presenting with persistent cough and elevated serum ferritin levels. Heart Lung 35:112\u2013116","journal-title":"Heart Lung"},{"key":"37_CR17","doi-asserted-by":"publisher","first-page":"340","DOI":"10.1016\/j.hrtlng.2009.07.010","volume":"39","author":"BA Cunha","year":"2010","unstructured":"Cunha BA, Pherez FM, Katz DS (2010) Fever of unknown origin (FUO) due to a solitary cavitary lung lesion: the deadly ferritin-laced doughnut. Heart Lung 39:340\u2013344","journal-title":"Heart Lung"},{"key":"37_CR18","doi-asserted-by":"publisher","first-page":"1138.e1","DOI":"10.1016\/j.amjmed.2015.06.001","volume":"128","author":"BA Cunha","year":"2015","unstructured":"Cunha BA, Lortholary O, Cunha CB (2015) Fever of unknown origin: a clinical approach. Am J Med 128:1138.e1\u20131138.e15. doi: 10.1016\/j.amjmed.2015.06.001","journal-title":"Am J Med"},{"key":"37_CR19","first-page":"35","volume":"11","author":"DT Durack","year":"1991","unstructured":"Durack DT, Street AC (1991) Fever of unknown origin \u2013 reexamined and redefined. Curr Clin Top Infect Dis 11:35\u201351","journal-title":"Curr Clin Top Infect Dis"},{"key":"37_CR20","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1007\/s00259-009-1185-y","volume":"37","author":"N Jasper","year":"2010","unstructured":"Jasper N, Dabritz J, Frosch M, Loeffler M, Weckesser M, Foell D (2010) Diagnostic value of (18F)-FDG PET\/CT in children with fever of unknown origin or unexplained signs of inflammation. Eur J Nucl Med Mol Imaging 37:136\u2013145","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"37_CR21","doi-asserted-by":"publisher","first-page":"158","DOI":"10.1016\/S1556-0864(15)30045-9","volume":"2","author":"MS Kim","year":"2007","unstructured":"Kim MS, Koh JS, Baek HJ, Ryoo BY, Kim CH, Lee JC (2007) Neoplastic fever caused by lung cancer. J Thorac Oncol 2:158\u2013159","journal-title":"J Thorac Oncol"},{"key":"37_CR22","doi-asserted-by":"publisher","DOI":"10.1515\/9781400869831","volume-title":"Fever: its biology, evolution, and function","author":"MJ Kluge","year":"2015","unstructured":"Kluge MJ (2015) Fever: its biology, evolution, and function. Princeton University Press, Princeton"},{"key":"37_CR23","doi-asserted-by":"publisher","first-page":"618","DOI":"10.1001\/archinte.1996.00440060036004","volume":"156","author":"DC Knockaert","year":"1996","unstructured":"Knockaert DC, Dujardin KS, Bobbaers HJ (1996) Long-term follow-up of patients with undiagnosed fever of unknown origin. Arch Intern Med 156:618\u2013620","journal-title":"Arch Intern Med"},{"key":"37_CR24","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1007\/s12149-011-0470-6","volume":"25","author":"K Kubota","year":"2011","unstructured":"Kubota K, Nakamoto Y, Tamaki N, Kanegae K, Fukuda H, Kaneda T, Kitajima K, Tateishi U, Morooka M, Ito K, Minamimoto R, Murakami K (2011) FDG-PET for the diagnosis of fever of unknown origin: a Japanese multi-center study. Ann Nucl Med 25:355\u2013364","journal-title":"Ann Nucl Med"},{"key":"37_CR25","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1016\/j.ijid.2007.04.013","volume":"12","author":"Y Kucukardali","year":"2008","unstructured":"Kucukardali Y, Oncul O, Cavuslu S, Danaci M, Calangu S, Erdem H, Topcu AW, Adibelli Z, Akova M, Karaali EA, Ozel AM, Bolaman Z, Caka B, Cetin B, Coban E, Karabay O, Karakoc C, Karan MA, Korkmaz S, Sahin GO, Pahsa A, Sirmatel F, Solmazgul E, Ozmen N, Tokatli I, Uzun C, Yakupoglu G, Besirbellioglu BA, Gul HC, Fever of Unknown Origin Study Group (2008) The spectrum of diseases causing fever of unknown origin in Turkey: a multicenter study. Int J Infect Dis 12:71\u201379","journal-title":"Int J Infect Dis"},{"key":"37_CR26","first-page":"183","volume":"3","author":"I Kuhajda","year":"2015","unstructured":"Kuhajda I, Zarogoulidis K, Tsirgogianni K, Tsavlis D, Kioumis I, Kosmidis C, Tsakiridis K, Mpakas A, Zarogoulidis P, Zissimopoulos A, Baloukas D, Kuhajda D (2015) Lung abscess-etiology, diagnostic and treatment options. Ann Transl Med 3:183","journal-title":"Ann Transl Med"},{"issue":"Suppl 32","key":"37_CR27","doi-asserted-by":"crossref","first-page":"69s","DOI":"10.1183\/09031936.01.18s320069","volume":"18","author":"C Lambin","year":"2001","unstructured":"Lambin C, Bergoin C, Saelens T, Wallaert B (2001) Interstitial lung disease in collagen vascular disease. Eur Respir J 18(Suppl 32):69s\u201392s","journal-title":"Eur Respir J"},{"key":"37_CR28","doi-asserted-by":"publisher","first-page":"240","DOI":"10.1016\/S0002-9343(99)00223-5","volume":"107","author":"J Ma\u00f1\u00e1","year":"1999","unstructured":"Ma\u00f1\u00e1 J, Gomez-Vaquero C, Montero A, Salazar A, Marcoval J, Valverde J, Manresa F, Pujol R (1999) L\u00f6fgren\u2019s syndrome revisted: a stady of 186 patients. Am J Med 107:240\u2013245","journal-title":"Am J Med"},{"key":"37_CR29","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1007\/s11739-008-0129-z","volume":"3","author":"P Mansueto","year":"2008","unstructured":"Mansueto P, Di Lorenzo G, Rizzo M, Di Rosa S, Vitale G, Rini G, Mansueto S, Affronti M (2008) Fever of unknown origin in a Mediterranean survey from a division of internal medicine: report of 91 cases during a 12-year-period (1991\u20132002). Intern Emerg Med 3:219\u2013225","journal-title":"Intern Emerg Med"},{"key":"37_CR30","first-page":"35","volume":"48","author":"J Meller","year":"2007","unstructured":"Meller J, Sahlmann CO, Scheel AK (2007) 18F-FDG PET and PET\/CT in fever of unknown origin. J Nucl Med 48:35\u201345","journal-title":"J Nucl Med"},{"key":"37_CR31","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1007\/s10067-002-0680-3","volume":"22","author":"A Mert","year":"2003","unstructured":"Mert A, Ozaras R, Tabak F (2003) Fever of unknown origin: a review of 20 patients with adult-onset Still\u2019s disease. Clin Rhematol 22:89\u201393","journal-title":"Clin Rhematol"},{"key":"37_CR32","doi-asserted-by":"publisher","first-page":"290","DOI":"10.1136\/postgradmedj-2013-203255rep","volume":"90","author":"A Millet","year":"2014","unstructured":"Millet A, Pederzoli-Ribeil M, Guillevin L, Witko-Sarsat V, Mouthon L (2014) Antineutrophil cytoplasmic antibody-associated vasculitides: is it time to split up the group? Postgrad Med J 90:290\u2013296","journal-title":"Postgrad Med J"},{"key":"37_CR33","doi-asserted-by":"publisher","first-page":"289","DOI":"10.4103\/0256-4947.65259","volume":"30","author":"MA Moawad","year":"2010","unstructured":"Moawad MA, Bassil H, Elsherif M, Ibrahim A, Elnaggar M, Edathodu J, Alharthi A, Albugami M, Sabry A, Shoukri M, Bakhsh I, Laudon U (2010) Fever of unknown origin: 98 cases from Saudi Arabia. Ann Saudi Med 30:289\u2013294","journal-title":"Ann Saudi Med"},{"key":"37_CR34","doi-asserted-by":"publisher","first-page":"545","DOI":"10.1001\/archinte.163.5.545","volume":"163","author":"O Mourad","year":"2003","unstructured":"Mourad O, Palda V, Detsky AS (2003) A comprehensive evidence-based approach to fever of unknown origin. Arch Intern Med 163:545\u2013551","journal-title":"Arch Intern Med"},{"key":"37_CR35","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1016\/j.hrtlng.2014.09.003","volume":"44","author":"S Mu\u00f1oz-G\u00f3mez","year":"2015","unstructured":"Mu\u00f1oz-G\u00f3mez S, Cunha BA (2015) Fever of unknown origin (FUO) due to Legionnaire\u2019s disease. Heart Lung 44:72\u201374","journal-title":"Heart Lung"},{"key":"37_CR36","unstructured":"NICE (2014) Pneumonia in adults: diagnosis and management. Clinical guideline (CG191) Published date: December 2014 https:\/\/www.nice.org.uk\/guidance\/cg191 . Accessed on 14 Jan 2017"},{"key":"37_CR37","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1097\/00005792-196102000-00001","volume":"40","author":"RG Petersdorf","year":"1961","unstructured":"Petersdorf RG, Beeson PB (1961) Fever of unexplained origin: report on 100 cases. Medicine (Baltimore) 40:1\u201330","journal-title":"Medicine (Baltimore)"},{"key":"37_CR38","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1097\/MNM.0b013e3282f3ea02","volume":"29","author":"N Seshadri","year":"2008","unstructured":"Seshadri N, Solanki CK, Balan K (2008) Utility of 111In-labeled leukocyte scintigraphy in patients with fever of unknown origin in an era of changing disease spectrum and investigational techniques. Nucl Med Commun 29:277\u2013282","journal-title":"Nucl Med Commun"},{"key":"37_CR39","first-page":"96","volume":"7","author":"S Sica","year":"1999","unstructured":"Sica S, Avino S, Glielmi G, Cicero SR (1999) Incidence of fever of difficult diagnosis observed from January 1990 to August 1998. Infez Med 7:96\u2013104. (Article in Italian)","journal-title":"Infez Med"},{"issue":"9093","key":"37_CR40","doi-asserted-by":"publisher","first-page":"1782","DOI":"10.1016\/S0140-6736(05)63618-5","volume":"350","author":"R Sood","year":"1997","unstructured":"Sood R, Agarwal V, Mukhopadhyay S (1997) Tuberculosis mediastinal adenopathy presenting as fever of unknown origin. Lancet 350(9093):1782","journal-title":"Lancet"},{"key":"37_CR41","doi-asserted-by":"publisher","first-page":"851","DOI":"10.1016\/S1470-2045(05)70346-6","volume":"6","author":"HT S\u00f8rensen","year":"2005","unstructured":"S\u00f8rensen HT, Mellemkjaer L, Skriver MV, Johnsen SP, N\u00f8rg\u00e5rd B, Olsen JH, Baron JA (2005) Fever of unknown origin and cancer: a population-based study. Lancet Oncol 6:851\u2013855","journal-title":"Lancet Oncol"},{"key":"37_CR42","doi-asserted-by":"publisher","first-page":"649","DOI":"10.1016\/j.cger.2007.03.004","volume":"23","author":"MH Tal","year":"2007","unstructured":"Tal MH, Guller V, Gurevich A (2007) Fever of unknown origin in older adults. Clin Geriatr Med 23:649\u2013668","journal-title":"Clin Geriatr Med"},{"key":"37_CR43","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1056\/NEJMcpc020026","volume":"348","author":"LT Tanoue","year":"2003","unstructured":"Tanoue LT, Mark EJ (2003) Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 1-2003: a 43-year-old man with fever and night sweats. N Engl J Med 348:151\u2013161","journal-title":"N Engl J Med"},{"key":"37_CR44","doi-asserted-by":"publisher","first-page":"1033","DOI":"10.1001\/archinte.163.9.1033","volume":"163","author":"S Vanderschueren","year":"2003","unstructured":"Vanderschueren S, Knockaert D, Adriaenssens T, Demey W, Durnez A, Blockmans D, Bobbaers H (2003) From prolonged febrile illness to fever of unknown origin: the challenge continues. Arch Intern Med 163:1033\u20131041","journal-title":"Arch Intern Med"},{"key":"37_CR45","unstructured":"Verschakelen JA (2005) Sarcoidosis: imaging features. In: Drent M, Costabel U (eds) Sarcoidosis. Eur Respir Mono 10:265\u2013283"},{"key":"37_CR46","doi-asserted-by":"publisher","first-page":"1000","DOI":"10.1183\/09031936.04.00101303","volume":"24","author":"L Welker","year":"2004","unstructured":"Welker L, J\u00f6rres RA, Costabel U, Magnusen H (2004) Predictive value of BAL cell differentials in the diagnosis of interstitial lung diseases. Eur Respir J 24:1000\u20131006","journal-title":"Eur Respir J"},{"key":"37_CR47","doi-asserted-by":"publisher","first-page":"e518","DOI":"10.1016\/j.ijid.2009.06.009","volume":"14","author":"YK Zee","year":"2010","unstructured":"Zee YK, Soo RA (2010) Non-small cell lung cancer presenting with neoplastic fever at diagnosis and relapse. Int J Infect Dis 14:e518\u2013e521","journal-title":"Int J Infect Dis"}],"container-title":["Advances in Experimental Medicine and Biology","Clinical Management of Pulmonary Disorders and Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/5584_2017_37","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T22:28:54Z","timestamp":1750285734000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/5584_2017_37"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017]]},"ISBN":["9783319695440","9783319695457"],"references-count":47,"URL":"https:\/\/doi.org\/10.1007\/5584_2017_37","relation":{},"ISSN":["0065-2598","2214-8019"],"issn-type":[{"value":"0065-2598","type":"print"},{"value":"2214-8019","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017]]},"assertion":[{"value":"2 June 2017","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}}]}}