{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,12]],"date-time":"2025-08-12T21:58:37Z","timestamp":1755035917487,"version":"3.40.3"},"publisher-location":"Cham","reference-count":38,"publisher":"Springer International Publishing","isbn-type":[{"type":"print","value":"9783030712013"},{"type":"electronic","value":"9783030712020"}],"license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020]]},"DOI":"10.1007\/5584_2020_575","type":"book-chapter","created":{"date-parts":[[2020,9,10]],"date-time":"2020-09-10T17:04:33Z","timestamp":1599757473000},"page":"91-102","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Keyboard Contamination in Intensive Care Unit: Is Cleaning Enough? Prospective Research of In Situ Effectiveness of a Tea Tree Oil (KTEO) Film"],"prefix":"10.1007","author":[{"given":"Gabriele","family":"Melegari","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ramona","family":"Iseppi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martina","family":"Mariani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enrico","family":"Giuliani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valeria","family":"Caciagli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisabetta","family":"Bertellini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrizia","family":"Messi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alberto","family":"Barbieri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,9,11]]},"reference":[{"key":"575_CR1","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1016\/j.jhin.2018.01.018","volume":"99","author":"C Adlhart","year":"2018","unstructured":"Adlhart C, Verran J, Azevedo NF et al (2018) Surface modifications for antimicrobial effects in the healthcare setting: a critical overview. J Hosp Infect 99:239\u2013249","journal-title":"J Hosp Infect"},{"key":"575_CR2","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1016\/j.jhin.2017.09.007","volume":"98","author":"A Almatroudi","year":"2018","unstructured":"Almatroudi A, Tahir S, Hu H et al (2018) Staphylococcus aureus dry-surface biofilms are more resistant to heat treatment than traditional hydrated biofilms. J Hosp Infect 98:161\u2013167","journal-title":"J Hosp Infect"},{"key":"575_CR3","doi-asserted-by":"publisher","first-page":"1692","DOI":"10.1111\/j.1365-2672.2007.03711.x","volume":"104","author":"A Assere","year":"2008","unstructured":"Assere A, Oulahal N, Carpentier B (2008) Comparative evaluation of methods for counting surviving biofilm cells adhering to a polyvinyl chloride surface exposed to chlorine or drying. J Appl Microbiol 104:1692\u20131702","journal-title":"J Appl Microbiol"},{"key":"575_CR4","doi-asserted-by":"publisher","first-page":"16","DOI":"10.4103\/2008-7802.201923","volume":"8","author":"RA Ataee","year":"2017","unstructured":"Ataee RA, Ataee MH, Mehrabi Tavana A et al (2017) Bacteriological aspects of hand washing: a key for health promotion and infections control. Int J Prev Med 8:16","journal-title":"Int J Prev Med"},{"key":"575_CR5","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1016\/S0195-6701(07)60015-2","volume":"65","author":"JM Boyce","year":"2007","unstructured":"Boyce JM (2007) Environmental contamination makes an important contribution to hospital infection. J Hosp Infect 65:50\u201354","journal-title":"J Hosp Infect"},{"key":"575_CR6","doi-asserted-by":"publisher","first-page":"737","DOI":"10.1086\/661222","volume":"32","author":"JM Boyce","year":"2011","unstructured":"Boyce JM, Havill NL, Moore BA (2011) Terminal decontamination of patient rooms using an automated mobile UV light unit. Infect Control Hosp Epidemiol 32:737\u2013742","journal-title":"Infect Control Hosp Epidemiol"},{"key":"575_CR7","doi-asserted-by":"publisher","first-page":"465","DOI":"10.1067\/mic.2000.107267","volume":"28","author":"S Bures","year":"2000","unstructured":"Bures S, Fishbain JT, Uyehera CF et al (2000) Computer keyboards and faucet handles as reservoirs of nosocomial pathogens in the intensive care unit. Am J Infect Control 28:465\u2013471","journal-title":"Am J Infect Control"},{"key":"575_CR8","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1128\/CMR.19.1.50-62.2006","volume":"19","author":"CF Carson","year":"2006","unstructured":"Carson CF, Hammer KA, Riley TV (2006) Melaleuca alternifolia (tea tree) oil: a review of antimicrobial and other medicinal properties. Clin Microbiol Rev 19:50\u201362","journal-title":"Clin Microbiol Rev"},{"key":"575_CR9","doi-asserted-by":"publisher","first-page":"567","DOI":"10.1080\/14786419.2018.1490904","volume":"34","author":"C Cond\u00f2","year":"2020","unstructured":"Cond\u00f2 C, Anacarso I, Sabia C et al (2020) Antimicrobial activity of spices essential oils and its effectiveness on mature biofilms of human pathogens. Nat Prod Res 34:567\u2013574","journal-title":"Nat Prod Res"},{"key":"575_CR10","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1111\/lam.13127","volume":"68","author":"DM Costa","year":"2019","unstructured":"Costa DM, Johani K, Melo DS et al (2019) Biofilm contamination of high-touched surfaces in intensive care units: epidemiology and potential impacts. Lett Appl Microbiol 68:269\u2013276","journal-title":"Lett Appl Microbiol"},{"key":"575_CR11","doi-asserted-by":"publisher","first-page":"474","DOI":"10.1016\/j.ajic.2017.09.012","volume":"46","author":"A Das","year":"2018","unstructured":"Das A, Conti J, Hanrahan J et al (2018) Comparison of keyboard colonization before and after use in an inpatient setting and the effect of keyboard covers. Am J Infect Control 46:474\u2013476","journal-title":"Am J Infect Control"},{"key":"575_CR13","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1099\/00222615-32-3-195","volume":"32","author":"GJ Duckworth","year":"1990","unstructured":"Duckworth GJ, Jordens JZ (1990) Adherence and survival properties of an epidemic methicillin-resistant strain of Staphylococcus aureus compared with those of methicillin-sensitive strains. J Med Microbiol 32:195\u2013200","journal-title":"J Med Microbiol"},{"key":"575_CR14","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1016\/j.cimid.2016.06.002","volume":"47","author":"M El-Azizi","year":"2016","unstructured":"El-Azizi M, Farag N, Khardori N (2016) Efficacy of selected biocides in the decontamination of common nosocomial bacterial pathogens in biofilm and planktonic forms. Comp Immunol Microbiol Infect Dis 47:60\u201371","journal-title":"Comp Immunol Microbiol Infect Dis"},{"key":"575_CR15","doi-asserted-by":"publisher","first-page":"1341","DOI":"10.1111\/imj.13642","volume":"47","author":"SA Fernando","year":"2017","unstructured":"Fernando SA, Gray TJ, Gottlieb T (2017) Healthcare-acquired infections: prevention strategies. Intern Med J 47:1341\u20131351","journal-title":"Intern Med J"},{"key":"575_CR16","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1016\/j.antiviral.2010.11.010","volume":"89","author":"A Garozzo","year":"2011","unstructured":"Garozzo A, Timpanaro R, Stivala A et al (2011) Activity of Melaleuca alternifolia (tea tree) oil on Influenza virus A\/PR\/8: study on the mechanism of action. Antivir Res 89:83\u201388","journal-title":"Antivir Res"},{"key":"575_CR17","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1016\/j.iccn.2018.02.009","volume":"47","author":"E Giuliani","year":"2018","unstructured":"Giuliani E, Lionte G, Ferri P et al (2018) The burden of not-weighted factors \u2013 nursing workload in a medical Intensive Care Unit. Intensive Crit Care Nurs 47:98\u2013101","journal-title":"Intensive Crit Care Nurs"},{"key":"575_CR18","doi-asserted-by":"publisher","first-page":"1089","DOI":"10.1016\/j.ajic.2016.06.012","volume":"44","author":"A Gostine","year":"2016","unstructured":"Gostine A, Gostine D, Donohue MD et al (2016) Evaluating the effectiveness of ultraviolet-C lamps for reducing keyboard contamination in the intensive care unit: a longitudinal analysis. Am J Infect Control 44:1089\u20131094","journal-title":"Am J Infect Control"},{"key":"575_CR19","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1086\/524331","volume":"29","author":"MK Hayden","year":"2018","unstructured":"Hayden MK, Blom DW, Lyle EA et al (2018) Risk of hand or glove contamination after contact with patients colonized with vancomycin-resistant enterococcus or the colonized patients environment. Infect Control Hosp Epidemiol 29:149\u2013154","journal-title":"Infect Control Hosp Epidemiol"},{"key":"575_CR20","unstructured":"International Organization for Standardization (ISO) (2017) Essential oil of Melaleuca, terpinen-4-ol type (tea tree oil). ISO 4730:2017. International Organization for Standardization (ISO), Geneva"},{"key":"575_CR21","doi-asserted-by":"publisher","first-page":"2302","DOI":"10.3390\/molecules24122302","volume":"24","author":"R Iseppi","year":"2019","unstructured":"Iseppi R, Brighenti V, Licata M et al (2019) Chemical characterization and evaluation of the antibacterial activity of essential oils from fibre-type Cannabis sativa L. (Hemp). Molecules 24:2302","journal-title":"Molecules"},{"key":"575_CR22","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1016\/j.jhin.2016.08.018","volume":"94","author":"G Kampf","year":"2016","unstructured":"Kampf G (2016) Acquired resistance to chlorexidine \u2013 is it time to establish an \u2018antiseptic stewardship\u2019 initiative? J Hosp Infect 94:213\u2013227","journal-title":"J Hosp Infect"},{"key":"575_CR23","doi-asserted-by":"publisher","first-page":"416","DOI":"10.1016\/j.ajic.2011.06.013","volume":"40","author":"J Kang","year":"2012","unstructured":"Kang J, Sickbert-Bennett EE, Brown V et al (2012) Relative frequency of health care-associated pathogens by infection site at university hospital from 1980 to 2008. Am J Infect Control 40:416\u2013420","journal-title":"Am J Infect Control"},{"key":"575_CR24","doi-asserted-by":"publisher","unstructured":"MacGibeny MA, Wassef C (2020) Preventing adverse cutaneous reactions from amplified hygiene practices during the COVID-19 pandemic: how dermatologists can help through anticipatory guidance. Arch Dermatol Res:1\u20133. https:\/\/doi.org\/10.1007\/s00403-020-02086-x","DOI":"10.1007\/s00403-020-02086-x"},{"key":"575_CR25","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1016\/j.ajic.2010.10.016","volume":"39","author":"ET Martin","year":"2011","unstructured":"Martin ET, Qin X, Baden H et al (2011) Randomized double-blind crossover trial of ultraviolet light-sanitized keyboards in a pediatric hospital. Am J Infect Control 39:433\u2013435","journal-title":"Am J Infect Control"},{"key":"575_CR26","doi-asserted-by":"publisher","first-page":"639","DOI":"10.1093\/jac\/45.5.639","volume":"45","author":"J May","year":"2000","unstructured":"May J, Chan CH, King A et al (2000) Time-kill studies of tea tree oils on clinical isolates. J Antimicrob Chemother 45:639\u2013643","journal-title":"J Antimicrob Chemother"},{"key":"575_CR27","doi-asserted-by":"publisher","unstructured":"Melegari G, Giuliani E, Maini G et al (2020) Novel coronavirus (2019-nCov): do you have enough intensive care units? Med Intensiva. https:\/\/doi.org\/10.1016\/j.medin.2020.04.007","DOI":"10.1016\/j.medin.2020.04.007"},{"key":"575_CR28","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1007\/s10453-015-9371-9","volume":"31","author":"P Messi","year":"2015","unstructured":"Messi P, Sabia C, Anacarso I et al (2015) Prevalence of multi-drug resistant (MDR) bacteria in air samples from indoor and outdoor environments. Aerobiologia 31:381\u2013387","journal-title":"Aerobiologia"},{"key":"575_CR29","first-page":"6312","volume":"5","author":"TTA My","year":"2020","unstructured":"My TTA, Loan HTP, Hai NTT et al (2020) Evaluation of the inhibitory activities of COVID-19 of Melaleuca cajuputi oil using docking simulation. Chem Select 5:6312\u20136320","journal-title":"Chem Select"},{"key":"575_CR30","doi-asserted-by":"publisher","first-page":"e57","DOI":"10.1016\/j.ajic.2018.04.201","volume":"46","author":"AM Nasr","year":"2018","unstructured":"Nasr AM, Mostafa MS, Arnaout HH et al (2018) The effect of exposure to sub-inhibitory concentrations of hypochlorite and quaternary ammonium compounds on antimicrobial susceptibility of Pseudomonas aeruginosa. Am J Infect Control 46:e57\u2013e63","journal-title":"Am J Infect Control"},{"issue":"Suppl","key":"575_CR31","doi-asserted-by":"publisher","first-page":"121S","DOI":"10.1046\/j.1365-2672.92.5s1.12.x","volume":"92","author":"AD Russell","year":"2002","unstructured":"Russell AD (2002) Introduction of biocides into clinical practice and the impact on antibiotic-resistant bacteria. J Appl Microbiol 92(Suppl):121S\u2013135S","journal-title":"J Appl Microbiol"},{"key":"575_CR32","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1186\/s40560-015-0120-5","volume":"3","author":"V Russotto","year":"2015","unstructured":"Russotto V, Cortegiani A, Raineri SM et al (2015) Bacterial contamination of inanimate surfaces and equipement in the intensive care unit. J Intensive Care 3:54","journal-title":"J Intensive Care"},{"key":"575_CR33","doi-asserted-by":"publisher","first-page":"212","DOI":"10.5455\/jice.20160331064446","volume":"5","author":"H Sakkas","year":"2016","unstructured":"Sakkas H, Gousia P, Economou V et al (2016) In vitro antimicrobial activity of five essential oils on multidrug resistant Gram-negative clinical isolates. J Intercult Ethnopharmacol 5:212\u2013218","journal-title":"J Intercult Ethnopharmacol"},{"key":"575_CR34","doi-asserted-by":"publisher","first-page":"302","DOI":"10.1086\/502200","volume":"24","author":"M Schultz","year":"2003","unstructured":"Schultz M, Gill J, Zubairi S et al (2003) Bacterial contamination of computer keyboards in a teaching hospital. Infect Control Hosp Epidemiol 24:302\u2013303","journal-title":"Infect Control Hosp Epidemiol"},{"key":"575_CR35","first-page":"551","volume":"37","author":"S Stefani","year":"2014","unstructured":"Stefani S, Giovanelli I, Anacarso I et al (2014) Prevalence and characterization of extended-spectrum \u03b2-lactamase-producing Enterobacteriaceae in food-producing animals in Northern Italy. New Microbiol 37:551\u2013555","journal-title":"New Microbiol"},{"issue":"46","key":"575_CR36","doi-asserted-by":"publisher","first-page":"pii=1800516","DOI":"10.2807\/1560-7917.ES.2018.23.46.1800516","volume":"23","author":"C Suetens","year":"2018","unstructured":"Suetens C, Latour K, K\u00e4rki T et al (2018) The Healthcare-Associated Infections Prevalence Study Group. Prevalence of healthcare-associated infections, estimated incidence and composite antimicrobial resistance index in acute care hospitals and long-term care facilities: results from two European point prevalence surveys, 2016 to 2017. Euro Surveill 23(46):pii=1800516","journal-title":"Euro Surveill"},{"key":"575_CR37","doi-asserted-by":"publisher","first-page":"2786","DOI":"10.3390\/nu11112786","volume":"11","author":"M Valdivieso-Ugarte","year":"2019","unstructured":"Valdivieso-Ugarte M, Gomez-Llorente C, Plaza-D\u00edaz J et al (2019) Antimicrobial, antioxidant, and immunomodulatory properties of essential oils: a systematic review. Nutrients 11:2786","journal-title":"Nutrients"},{"key":"575_CR38","doi-asserted-by":"publisher","first-page":"e19","DOI":"10.1016\/j.ajic.2008.09.001","volume":"36","author":"AP Wilson","year":"2008","unstructured":"Wilson AP, Ostro P, Magnussen M et al (2008) Keyboard Study Group. Laboratory and in-use assessment of methicillin-resistant Staphylococcus aureus contamination of ergonomic computer keyboards for ward use. Am J Infect Control 36:e19\u2013e25","journal-title":"Am J Infect Control"},{"key":"575_CR39","doi-asserted-by":"publisher","first-page":"6","DOI":"10.2174\/1874285801408010006","volume":"8","author":"PSX Yap","year":"2014","unstructured":"Yap PSX, Yiap BC, Ping HC et al (2014) Essential oils, a new horizon in combating bacterial antibiotic resistance. Open Microbiol J 8:6\u201314","journal-title":"Open Microbiol J"}],"container-title":["Advances in Experimental Medicine and Biology","Advances in Microbiology, Infectious Diseases and Public Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/5584_2020_575","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,24]],"date-time":"2021-04-24T17:05:21Z","timestamp":1619283921000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/5584_2020_575"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020]]},"ISBN":["9783030712013","9783030712020"],"references-count":38,"URL":"https:\/\/doi.org\/10.1007\/5584_2020_575","relation":{},"ISSN":["0065-2598","2214-8019"],"issn-type":[{"type":"print","value":"0065-2598"},{"type":"electronic","value":"2214-8019"}],"subject":[],"published":{"date-parts":[[2020]]},"assertion":[{"value":"11 September 2020","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}}]}}