{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,25]],"date-time":"2026-04-25T13:51:31Z","timestamp":1777125091125,"version":"3.51.4"},"publisher-location":"Cham","reference-count":18,"publisher":"Springer International Publishing","isbn-type":[{"value":"9783031019944","type":"print"},{"value":"9783031019951","type":"electronic"}],"license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021]]},"DOI":"10.1007\/5584_2021_659","type":"book-chapter","created":{"date-parts":[[2022,1,14]],"date-time":"2022-01-14T15:04:40Z","timestamp":1642172680000},"page":"93-100","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Ultrastructural and Immunohistochemical Diagnosis of a Neonatal Herpes Simplex Virus Infection Presenting as Fulminant Hepatitis: A Case Report"],"prefix":"10.1007","author":[{"given":"Valentina","family":"Papa","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nunzio Cosimo Mario","family":"Salfi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberta","family":"Costa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ilaria","family":"Bettocchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emilia","family":"Ricci","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Duccio Maria","family":"Cordelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesca","family":"Locatelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabio","family":"Caramelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanna","family":"Cenacchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,7,24]]},"reference":[{"issue":"2","key":"659_CR1","doi-asserted-by":"publisher","first-page":"87","DOI":"10.4103\/2249-4847.96761","volume":"1","author":"S Abuhasna","year":"2012","unstructured":"Abuhasna S, Shihab Z, Al Niyadi S, Tatari H, Al Jundi A, Atwa K (2012) Neonatal herpes simplex fulminant hepatitis successfully treated with acyclovir. J Clin Neonatol 1(2):87. https:\/\/doi.org\/10.4103\/2249-4847.96761","journal-title":"J Clin Neonatol"},{"issue":"4","key":"659_CR2","doi-asserted-by":"publisher","first-page":"663","DOI":"10.1007\/s12024-019-00147-w","volume":"15","author":"JM Basinger","year":"2019","unstructured":"Basinger JM, Fiester SE, Fulcher JW (2019) Mortality from neonatal herpes simplex viremia causing severe hepatitis. Forensic Sci Med Pathol 15(4):663\u2013666. https:\/\/doi.org\/10.1007\/s12024-019-00147-w","journal-title":"Forensic Sci Med Pathol"},{"key":"659_CR3","doi-asserted-by":"publisher","unstructured":"Cenacchi G, Peterle E, Fanin M, Papa V, Salaroli R, Angelini C (2013) Ultrastructural changes in LGMD1F. Neuropathology 33(3). https:\/\/doi.org\/10.1111\/neup.12003","DOI":"10.1111\/neup.12003"},{"issue":"2","key":"659_CR4","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1016\/j.micron.2005.10.001","volume":"37","author":"A Curry","year":"2006","unstructured":"Curry A, Appleton H, Dowsett B (2006) Application of transmission electron microscopy to the clinical study of viral and bacterial infections: present and future. Micron 37(2):91\u2013106. https:\/\/doi.org\/10.1016\/j.micron.2005.10.001","journal-title":"Micron"},{"issue":"12","key":"659_CR5","doi-asserted-by":"publisher","first-page":"4902","DOI":"10.3390\/v6124902","volume":"6","author":"CS Goldsmith","year":"2014","unstructured":"Goldsmith CS (2014) Morphologic differentiation of viruses beyond the family level. Viruses 6(12):4902\u20134913. https:\/\/doi.org\/10.3390\/v6124902","journal-title":"Viruses"},{"key":"659_CR6","doi-asserted-by":"publisher","unstructured":"Laue M (2010) Electron microscopy of viruses. In Methods in cell biology (vol 96, issue C). Elsevier. doi:https:\/\/doi.org\/10.1016\/S0091-679X(10)96001-9","DOI":"10.1016\/S0091-679X(10)96001-9"},{"issue":"3","key":"659_CR7","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1016\/j.siny.2017.02.006","volume":"22","author":"L Lehtonen","year":"2017","unstructured":"Lehtonen L, Gimeno A, Parra-Llorca A, Vento M (2017) Early neonatal death: a challenge worldwide. Semin Fetal Neonatal Med 22(3):153\u2013160. https:\/\/doi.org\/10.1016\/j.siny.2017.02.006","journal-title":"Semin Fetal Neonatal Med"},{"issue":"2","key":"659_CR8","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1891\/0730-0832.39.2.92","volume":"39","author":"CC McPherson","year":"2020","unstructured":"McPherson CC (2020) Neonatal herpes simplex virus: the long road to improved outcomes. Neonatal Netw 39(2):92\u201398. https:\/\/doi.org\/10.1891\/0730-0832.39.2.92","journal-title":"Neonatal Netw"},{"issue":"7","key":"659_CR9","first-page":"1235","volume":"71","author":"NV Motorna","year":"2018","unstructured":"Motorna NV, Kvitnitskaya-Ryzhova TY, Rybalko SL, Starosyla DB, Kaminsky RF, Savosko SI, Sokurenko LM, Chaikovsky YB (2018) Experimental study of the liver ultrastructure in the presence of infection with herpes simplex virus 1. Wiadomosci Lekarskie (Warsaw, Poland: 1960) 71(7):1235\u20131241","journal-title":"Wiadomosci Lekarskie (Warsaw, Poland: 1960)"},{"issue":"3","key":"659_CR10","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1128\/mBio.00825-17","volume":"8","author":"WW Newcomb","year":"2017","unstructured":"Newcomb WW, Fontana J, Winkler DC, Cheng N, Bernard Heymann J, Stevena AC (2017) The primary enveloped virion of herpes simplex virus 1: its role in nuclear egress. MBio 8(3):1\u201314. https:\/\/doi.org\/10.1128\/mBio.00825-17","journal-title":"MBio"},{"issue":"8","key":"659_CR11","doi-asserted-by":"publisher","first-page":"446","DOI":"10.1111\/1751-2980.12640","volume":"19","author":"A Noor","year":"2018","unstructured":"Noor A, Panwala A, Forouhar F, Wu GY (2018) Hepatitis caused by herpes viruses: a review. J Dig Dis 19(8):446\u2013455. https:\/\/doi.org\/10.1111\/1751-2980.12640","journal-title":"J Dig Dis"},{"issue":"4","key":"659_CR12","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1097\/PEC.0000000000002077","volume":"36","author":"S Ramgopal","year":"2020","unstructured":"Ramgopal S, Wilson PM, Florin TA (2020) Diagnosis and management of neonatal herpes simplex infection in the emergency department. Pediatr Emerg Care 36(4):196\u2013204. https:\/\/doi.org\/10.1097\/PEC.0000000000002077","journal-title":"Pediatr Emerg Care"},{"issue":"8","key":"659_CR13","doi-asserted-by":"publisher","first-page":"491","DOI":"10.1042\/bc20070173","volume":"100","author":"P Roingeard","year":"2008","unstructured":"Roingeard P (2008) Viral detection by electron microscopy: past, present and future. Biol Cell 100(8):491\u2013501. https:\/\/doi.org\/10.1042\/bc20070173","journal-title":"Biol Cell"},{"issue":"1","key":"659_CR14","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1002\/rmv.2019","volume":"29","author":"P Roingeard","year":"2019","unstructured":"Roingeard P, Raynal PI, Eymieux S, Blanchard E (2019) Virus detection by transmission electron microscopy: still useful for diagnosis and a plus for biosafety. Rev Med Virol 29(1):1\u20139. https:\/\/doi.org\/10.1002\/rmv.2019","journal-title":"Rev Med Virol"},{"key":"659_CR15","doi-asserted-by":"publisher","unstructured":"Shahani L (2016) Fulminant hepatic failure secondary to acyclovir-resistant herpes simplex virus. BMJ Case Rep 2016. https:\/\/doi.org\/10.1136\/bcr-2016-216322","DOI":"10.1136\/bcr-2016-216322"},{"key":"659_CR16","doi-asserted-by":"publisher","unstructured":"Then EO, Gayam V, Are VS, Sunkara T, Gaduputi V (2019) Herpes simplex virus hepatitis: a brief review of an oft-overlooked pathology. Cureus 11(3). https:\/\/doi.org\/10.7759\/cureus.4313","DOI":"10.7759\/cureus.4313"},{"issue":"4","key":"659_CR17","doi-asserted-by":"publisher","first-page":"480","DOI":"10.23736\/S0026-4784.17.04107-7","volume":"70","author":"G Tosone","year":"2018","unstructured":"Tosone G, Simeone D, Spera AM, Viceconte G, Bianco V, Orlando R (2018) Epidemiology and pathogenesis of fulminant viral hepatitis in pregnant women. Minerva Ginecol 70(4):480\u2013486. https:\/\/doi.org\/10.23736\/S0026-4784.17.04107-7","journal-title":"Minerva Ginecol"},{"issue":"7","key":"659_CR18","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1111\/petr.13021","volume":"21","author":"R Vincenzi","year":"2017","unstructured":"Vincenzi R, Fonseca EA, Roda KMO, Porta G, Candido HL, Benavides MR, Leite KRM, Afonso RC, Turine-Neto P, Ribeiro CMF, Chapchap P, Seda-Neto J (2017) Living donor liver transplantation for neonatal fulminant hepatitis due to herpes simplex virus infection. Pediatr Transplant 21(7):1\u20134. https:\/\/doi.org\/10.1111\/petr.13021","journal-title":"Pediatr Transplant"}],"updated-by":[{"DOI":"10.1007\/5584_2021_688","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2021,11,26]],"date-time":"2021-11-26T00:00:00Z","timestamp":1637884800000}}],"container-title":["Advances in Experimental Medicine and Biology","Advances in Microbiology, Infectious Diseases and Public Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/5584_2021_659","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,4]],"date-time":"2022-05-04T22:04:15Z","timestamp":1651701855000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/5584_2021_659"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021]]},"ISBN":["9783031019944","9783031019951"],"references-count":18,"URL":"https:\/\/doi.org\/10.1007\/5584_2021_659","relation":{"correction":[{"id-type":"doi","id":"10.1007\/5584_2021_688","asserted-by":"object"}]},"ISSN":["0065-2598","2214-8019"],"issn-type":[{"value":"0065-2598","type":"print"},{"value":"2214-8019","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021]]},"assertion":[{"value":"24 July 2021","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}}]}}