{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T15:07:49Z","timestamp":1790348869776,"version":"4.1.0"},"publisher-location":"New York, NY","reference-count":12,"publisher":"Springer US","isbn-type":[{"value":"9781071620175","type":"print"},{"value":"9781071620182","type":"electronic"}],"license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021]]},"DOI":"10.1007\/7651_2021_398","type":"book-chapter","created":{"date-parts":[[2022,1,14]],"date-time":"2022-01-14T04:49:48Z","timestamp":1642135788000},"page":"157-165","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Tracheal In Vitro Reconstruction Using a Decellularized Bio-Scaffold in Combination with a Rotating Bioreactor"],"prefix":"10.1007","author":[{"given":"Georgia","family":"Pennarossa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matteo","family":"Ghiringhelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fulvio","family":"Gandolfi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiziana A. L.","family":"Brevini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,5,6]]},"reference":[{"key":"398_CR1","doi-asserted-by":"publisher","first-page":"437","DOI":"10.1016\/j.jtcvs.2009.10.002","volume":"139","author":"T Go","year":"2010","unstructured":"Go T, Jungebluth P, Baiguero S et al (2010) Both epithelial cells and mesenchymal stem cell-derived chondrocytes contribute to the survival of tissue-engineered airway transplants in pigs. J Thorac Cardiovasc Surg 139:437\u2013443","journal-title":"J Thorac Cardiovasc Surg"},{"key":"398_CR2","doi-asserted-by":"publisher","first-page":"1995","DOI":"10.1016\/S0003-4975(02)03564-6","volume":"73","author":"HC Grillo","year":"2002","unstructured":"Grillo HC (2002) Tracheal replacement: a critical review. Ann Thorac Surg 73:1995\u20132004","journal-title":"Ann Thorac Surg"},{"key":"398_CR3","doi-asserted-by":"crossref","unstructured":"Aoki FG, Varma R, Marin-Araujo AE et al (2019) De-epithelialization of porcine tracheal allografts as an approach for tracheal tissue engineering. Sci Rep 9","DOI":"10.1038\/s41598-019-48450-4"},{"key":"398_CR4","doi-asserted-by":"crossref","unstructured":"Birchall M, Macchiarini P (2008) Airway transplantation: a debate worth having? https:\/\/pubmed.ncbi.nlm.nih.gov\/18431223\/","DOI":"10.1097\/TP.0b013e31816a10e4"},{"key":"398_CR5","doi-asserted-by":"crossref","unstructured":"Macchiarini P (2004) Trachea-guided generation: D\u00e9j\u00e0 vu all over again? https:\/\/pubmed.ncbi.nlm.nih.gov\/15224015\/","DOI":"10.1016\/j.jtcvs.2003.11.069"},{"key":"398_CR6","doi-asserted-by":"crossref","unstructured":"Pennarossa G, Ghiringhelli M, Gandolfi F et al (2020) Whole-ovary decellularization generates an effective 3D bioscaffold for ovarian bioengineering. J Assist Reprod Genet:1\u201311","DOI":"10.1007\/s10815-020-01784-9"},{"key":"398_CR7","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1007\/978-1-0716-1246-0_9","volume":"2273","author":"G Pennarossa","year":"2021","unstructured":"Pennarossa G, Ghiringhelli M, Gandolfi F et al (2021) Creation of a bioengineered ovary: isolation of female germline stem cells for the repopulation of a decellularized ovarian bioscaffold. Methods Mol Biol 2273:139\u2013149","journal-title":"Methods Mol Biol"},{"issue":"Pt B","key":"398_CR8","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1016\/j.ijsu.2015.06.066","volume":"23","author":"B Ekser","year":"2015","unstructured":"Ekser B, Cooper DKC, Tector AJ (2015) The need for xenotransplantation as a source of organs and cells for clinical transplantation. Int J Surg 23(Pt B):199\u2013204","journal-title":"Int J Surg"},{"key":"398_CR9","doi-asserted-by":"crossref","unstructured":"Michel SG, Madariaga MLL, Villani V, et al (2015) Current progress in xenotransplantation and organ bioengineering. https:\/\/pubmed.ncbi.nlm.nih.gov\/25496853\/","DOI":"10.1016\/j.ijsu.2014.12.011"},{"key":"398_CR10","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1111\/j.1399-3089.2009.00532.x","volume":"16","author":"HC Shi","year":"2009","unstructured":"Shi HC, Deng WJ, Pei C et al (2009) Biomechanical properties of adult-excised porcine trachea for tracheal xenotransplantation. Xenotransplantation 16:181\u2013186","journal-title":"Xenotransplantation"},{"key":"398_CR11","doi-asserted-by":"publisher","first-page":"4117","DOI":"10.1016\/j.biomaterials.2009.04.028","volume":"30","author":"CH Lin","year":"2009","unstructured":"Lin CH, Hsu S-h, Huang CE et al (2009) A scaffold-bioreactor system for a tissue-engineered trachea. Biomaterials 30:4117\u20134126","journal-title":"Biomaterials"},{"key":"398_CR12","doi-asserted-by":"publisher","first-page":"823","DOI":"10.1096\/fj.02-0462com","volume":"17","author":"K Kojima","year":"2003","unstructured":"Kojima K, Bonassar LJ, Roy AK et al (2003) A composite tissue-engineered trachea using sheep nasal chondrocyte and epithelial cells. FASEB J 17:823\u2013828","journal-title":"FASEB J"}],"container-title":["Methods in Molecular Biology","Bioreactors in Stem Cell Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/7651_2021_398","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,20]],"date-time":"2022-01-20T14:03:51Z","timestamp":1642687431000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/7651_2021_398"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021]]},"ISBN":["9781071620175","9781071620182"],"references-count":12,"URL":"https:\/\/doi.org\/10.1007\/7651_2021_398","relation":{},"ISSN":["1064-3745","1940-6029"],"issn-type":[{"value":"1064-3745","type":"print"},{"value":"1940-6029","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021]]},"assertion":[{"value":"6 May 2021","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}}]}}