{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T16:03:29Z","timestamp":1757779409475,"version":"3.37.3"},"publisher-location":"Berlin, Heidelberg","reference-count":71,"publisher":"Springer Berlin Heidelberg","isbn-type":[{"type":"print","value":"9783642157561"},{"type":"electronic","value":"9783642157578"}],"license":[{"start":{"date-parts":[[2010,1,1]],"date-time":"2010-01-01T00:00:00Z","timestamp":1262304000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2010]]},"DOI":"10.1007\/7854_2010_63","type":"book-chapter","created":{"date-parts":[[2010,6,25]],"date-time":"2010-06-25T10:40:00Z","timestamp":1277462400000},"page":"89-106","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Partial Rodent Genetic Models for Bipolar Disorder"],"prefix":"10.1007","author":[{"given":"Guang","family":"Chen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ioline D.","family":"Henter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Husseini K.","family":"Manji","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2010,6,26]]},"reference":[{"key":"63_CR1","volume-title":"Diagnostic and statistical manual of mental disorders","author":"American Psychiatric Association","year":"1997","unstructured":"American Psychiatric Association (1997) Diagnostic and statistical manual of mental disorders, 4th edn. American Psychiatric Publishing, Inc., Washington, DC","edition":"4"},{"key":"63_CR2","doi-asserted-by":"publisher","first-page":"1108","DOI":"10.1176\/appi.ajp.157.7.1108","volume":"157","author":"A Anand","year":"2000","unstructured":"Anand A, Verhoeff P, Seneca N, Zoghbi SS, Seibyl JP, Charney DS, Innis RB (2000) Brain SPECT imaging of amphetamine-induced dopamine release in euthymic bipolar disorder patients. Am J Psychiatry 157:1108\u20131114","journal-title":"Am J Psychiatry"},{"key":"63_CR3","first-page":"131","volume":"33","author":"H Anisman","year":"2008","unstructured":"Anisman H, Du L, Palkovits M, Faludi G, Kovacs GG, Szontagh-Kishazi P, Merali Z, Poulter MO (2008) Serotonin receptor subtype and p11 mRNA expression in stress-relevant brain regions of suicide and control subjects. J Psychiatry Neurosci 33:131\u2013141","journal-title":"J Psychiatry Neurosci"},{"key":"63_CR4","doi-asserted-by":"publisher","first-page":"1618","DOI":"10.1111\/j.1460-9568.2008.06471.x","volume":"28","author":"A Aonurm-Helm","year":"2008","unstructured":"Aonurm-Helm A, Jurgenson M, Zharkovsky T, Sonn K, Berezin V, Bock E, Zharkovsky A (2008) Depression-like behaviour in neural cell adhesion molecule (NCAM)-deficient mice and its reversal by an NCAM-derived peptide, FGL. Eur J Neurosci 28:1618\u20131628","journal-title":"Eur J Neurosci"},{"key":"63_CR5","doi-asserted-by":"publisher","first-page":"804","DOI":"10.1016\/j.biopsych.2004.01.009","volume":"55","author":"M Arai","year":"2004","unstructured":"Arai M, Itokawa M, Yamada K, Toyota T, Arai M, Haga S, Ujike H, Sora I, Ikeda K, Yoshikawa T (2004) Association of neural cell adhesion molecule 1 gene polymorphisms with bipolar affective disorder in Japanese individuals. Biol Psychiatry 55:804\u2013810","journal-title":"Biol Psychiatry"},{"key":"63_CR6","doi-asserted-by":"publisher","first-page":"476","DOI":"10.1056\/NEJMra035354","volume":"351","author":"RH Belmaker","year":"2004","unstructured":"Belmaker RH (2004) Bipolar disorder. N Engl J Med 351:476\u2013486","journal-title":"N Engl J Med"},{"key":"63_CR7","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1016\/j.bbr.2007.09.012","volume":"187","author":"F Benedetti","year":"2008","unstructured":"Benedetti F, Fresi F, Maccioni P, Smeraldi E (2008) Behavioural sensitization to repeated sleep deprivation in a mice model of mania. Behav Brain Res 187:221\u2013227","journal-title":"Behav Brain Res"},{"key":"63_CR8","first-page":"14","volume":"14","author":"M Beneyto","year":"2007","unstructured":"Beneyto M, Kristiansen LV, Oni-Orisan A, McCullumsmith RE, Meador-Woodruff JH (2007) Abnormal glutamate receptor expression in the medial temporal lobe in schizophrenia and mood disorders. Neuropsychopharmacology 14:14","journal-title":"Neuropsychopharmacology"},{"key":"63_CR9","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1038\/nrn1846","volume":"7","author":"O Berton","year":"2006","unstructured":"Berton O, Nestler EJ (2006) New approaches to antidepressant drug discovery: beyond monoamines. Nat Rev Neurosci 7:137\u2013151","journal-title":"Nat Rev Neurosci"},{"key":"63_CR10","doi-asserted-by":"publisher","first-page":"1319","DOI":"10.1038\/ng1479","volume":"36","author":"EB Binder","year":"2004","unstructured":"Binder EB, Salyakina D, Lichtner P, Wochnik GM, Ising M, Putz B, Papiol S, Seaman S, Lucae S, Kohli T, Kunzel HE, Fuchs B, Majer M et al (2004) Polymorphisms in FKBP5 are associated with increased recurrence of depressive episodes and rapid response to antidepressant treatment. Nat Genet 36:1319\u20131325","journal-title":"Nat Genet"},{"key":"63_CR11","doi-asserted-by":"publisher","first-page":"1291","DOI":"10.1001\/jama.299.11.1291","volume":"299","author":"EB Binder","year":"2008","unstructured":"Binder EB, Bradley RG, Liu W, Epstein MP, Deveau TC, Mercer KB, Tang Y, Gillespie CF, Heim CM, Nemeroff CB, Schwartz AC, Cubells JF, Ressler KJ (2008) Association of FKBP5 polymorphisms and childhood abuse with risk of posttraumatic stress disorder symptoms in adults. JAMA 299:1291\u20131305","journal-title":"JAMA"},{"key":"63_CR12","doi-asserted-by":"publisher","first-page":"879","DOI":"10.1046\/j.1471-4159.1999.720879.x","volume":"72","author":"G Chen","year":"1999","unstructured":"Chen G, Zeng WZ, Yuan PX, Huang LD, Jiang YM, Zhao ZH, Manji HK (1999) The mood-stabilizing agents lithium and valproate robustly increase the levels of the neuroprotective protein bcl-2 in the CNS. J Neurochem 72:879\u2013882","journal-title":"J Neurochem"},{"key":"63_CR13","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1016\/j.biopsych.2006.03.046","volume":"61","author":"L Christiansen","year":"2007","unstructured":"Christiansen L, Tan Q, Iachina M, Bathum L, Kruse TA, McGue M, Christensen K (2007) Candidate gene polymorphisms in the serotonergic pathway: influence on depression symptomatology in an elderly population. Biol Psychiatry 61:223\u2013230","journal-title":"Biol Psychiatry"},{"key":"63_CR14","doi-asserted-by":"publisher","first-page":"809","DOI":"10.1016\/j.neuron.2008.03.001","volume":"57","author":"JN Crawley","year":"2008","unstructured":"Crawley JN (2008) Behavioral phenotyping strategies for mutant mice. Neuron 57:809\u2013818","journal-title":"Neuron"},{"key":"63_CR15","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1007\/s12031-008-9122-2","volume":"37","author":"TK Creson","year":"2009","unstructured":"Creson TK, Yuan P, Manji HK, Chen G (2009) Evidence for involvement of ERK, PI3K, and RSK in induction of Bcl-2 by valproate. J Mol Neurosci 37:123\u2013134","journal-title":"J Mol Neurosci"},{"key":"63_CR16","doi-asserted-by":"publisher","first-page":"775","DOI":"10.1038\/nrd1825","volume":"4","author":"JF Cryan","year":"2005","unstructured":"Cryan JF, Holmes A (2005) The ascent of mouse: advances in modelling human depression and anxiety. Nat Rev Drug Discov 4:775\u2013790","journal-title":"Nat Rev Drug Discov"},{"key":"63_CR17","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1097\/YCO.0b013e3280117733","volume":"20","author":"JF Cryan","year":"2007","unstructured":"Cryan JF, Slattery DA (2007) Animal models of mood disorders: recent developments. Curr Opin Psychiatry 20:1\u20137","journal-title":"Curr Opin Psychiatry"},{"key":"63_CR18","doi-asserted-by":"publisher","first-page":"930","DOI":"10.1016\/j.neuron.2008.01.032","volume":"57","author":"IE Araujo de","year":"2008","unstructured":"de Araujo IE, Oliveira-Maia AJ, Sotnikova TD, Gainetdinov RR, Caron MG, Nicolelis MA, Simon SA (2008) Food reward in the absence of taste receptor signaling. Neuron 57:930\u2013941","journal-title":"Neuron"},{"key":"63_CR19","doi-asserted-by":"publisher","first-page":"1116","DOI":"10.1016\/j.biopsych.2006.02.013","volume":"59","author":"RS Duman","year":"2006","unstructured":"Duman RS, Monteggia LM (2006) A neurotrophic model for stress-related mood disorders. Biol Psychiatry 59:1116\u20131127","journal-title":"Biol Psychiatry"},{"key":"63_CR20","doi-asserted-by":"publisher","first-page":"714","DOI":"10.1177\/0269881106060241","volume":"20","author":"H Einat","year":"2006","unstructured":"Einat H (2006) Modelling facets of mania \u2013 new directions related to the notion of endophenotypes. J Psychopharmacol 20:714\u2013722","journal-title":"J Psychopharmacol"},{"key":"63_CR21","doi-asserted-by":"crossref","first-page":"7311","DOI":"10.1523\/JNEUROSCI.23-19-07311.2003","volume":"23","author":"H Einat","year":"2003","unstructured":"Einat H, Yuan P, Gould TD, Li J, Du J, Zhang L, Manji HK, Chen G (2003) The role of the extracellular signal-regulated kinase signaling pathway in mood modulation. J Neurosci 23:7311\u20137316","journal-title":"J Neurosci"},{"key":"63_CR22","doi-asserted-by":"publisher","first-page":"172","DOI":"10.1016\/j.bbr.2005.06.012","volume":"165","author":"H Einat","year":"2005","unstructured":"Einat H, Yuan P, Manji HK (2005) Increased anxiety-like behaviors and mitochondrial dysfunction in mice with targeted mutation of the Bcl-2 gene: further support for the involvement of mitochondrial function in anxiety disorders. Behav Brain Res 165:172\u2013180","journal-title":"Behav Brain Res"},{"key":"63_CR23","doi-asserted-by":"publisher","first-page":"448","DOI":"10.1038\/sj.mp.4002135","volume":"14","author":"SR Engel","year":"2009","unstructured":"Engel SR, Creson TK, Hao Y, Shen Y, Maeng S, Nekrasova T, Landreth GE, Manji HK, Chen G (2009) The extracellular signal-regulated kinase pathway contributes to the control of behavioral excitement. Mol Psychiatry 14:448\u2013461","journal-title":"Mol Psychiatry"},{"key":"63_CR24","doi-asserted-by":"publisher","first-page":"2660","DOI":"10.1038\/sj.npp.1301014","volume":"31","author":"SM Ferguson","year":"2006","unstructured":"Ferguson SM, Fasano S, Yang P, Brambilla R, Robinson TE (2006) Knockout of ERK1 enhances cocaine-evoked immediate early gene expression and behavioral plasticity. Neuropsychopharmacology 31:2660\u20132668","journal-title":"Neuropsychopharmacology"},{"issue":"9","key":"63_CR25","doi-asserted-by":"publisher","first-page":"1056","DOI":"10.1038\/ng.209","volume":"40","author":"MA Ferreira","year":"2008","unstructured":"Ferreira MA, O'Donovan MC, Meng YA, Jones IR, Ruderfer DM, Jones L, Fan J, Kirov G, Perlis RH, Green EK, Smoller JW, Grozeva D, Stone J, Nikolov I, Chambert K, Hamshere ML, Nimgaonkar VL, Moskvina V, Thase ME, Caesar S, Sachs GS, Franklin J, Gordon-Smith K, Ardlie KG, Gabriel SB, Fraser C, Blumenstiel B, Defelice M, Breen G, Gill M, Morris DW, Elkin A, Muir WJ, McGhee KA, Williamson R, Macintyre DJ, Maclean AW, St Clair D, Robinson M, Van Beck M, Pereira AC, Kandaswamy R, McQuillin A, Collier DA, Bass NJ, Young AH, Lawrence J, Nicol Ferrier I, Anjorin A, Farmer A, Curtis D, Scolnick EM, McGuffin P, Daly MJ, Corvin AP, Holmans PA, Blackwood DH, Gurling HM, Owen MJ, Purcell SM, Sklar P, Craddock N (2008) Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder. Nat Genet 40(9):1056\u20131058","journal-title":"Nat Genet"},{"key":"63_CR26","doi-asserted-by":"publisher","first-page":"10520","DOI":"10.1523\/JNEUROSCI.4388-06.2007","volume":"27","author":"M Fukui","year":"2007","unstructured":"Fukui M, Rodriguiz RM, Zhou J, Jiang SX, Phillips LE, Caron MG, Wetsel WC (2007) Vmat2 heterozygous mutant mice display a depressive-like phenotype. J Neurosci 27:10520\u201310529","journal-title":"J Neurosci"},{"key":"63_CR27","volume-title":"Manic-depressive illness: bipolar and recurrent unipolar disorders","author":"FK Goodwin","year":"2007","unstructured":"Goodwin FK, Jamison KR (2007) Manic-depressive illness: bipolar and recurrent unipolar disorders, 2nd edn. Oxford University Press, New York","edition":"2"},{"key":"63_CR28","doi-asserted-by":"publisher","first-page":"6590","DOI":"10.1523\/JNEUROSCI.5747-03.2004","volume":"24","author":"Y Hao","year":"2004","unstructured":"Hao Y, Creson T, Zhang L, Li P, Du F, Yuan P, Gould TD, Manji HK, Chen G (2004) Mood stabilizer valproate promotes ERK pathway-dependent cortical neuronal growth and neurogenesis. J Neurosci 24:6590\u20136599","journal-title":"J Neurosci"},{"key":"63_CR29","doi-asserted-by":"crossref","first-page":"333","DOI":"10.31887\/DCNS.2009.11.3\/jhunsberger","volume":"11","author":"J Hunsberger","year":"2009","unstructured":"Hunsberger J, Austin DR, Henter ID, Chen G (2009a) The neurotrophic and neuroprotective effects of psychotropic agents. Dialogues Clin Neurosci 11:333\u2013348","journal-title":"Dialogues Clin Neurosci"},{"key":"63_CR30","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1016\/j.brainres.2009.06.103","volume":"1293","author":"JG Hunsberger","year":"2009","unstructured":"Hunsberger JG, Austin DR, Chen G, Manji HK (2009b) Cellular mechanisms underlying affective resiliency: the role of glucocorticoid receptor- and mitochondrially-mediated plasticity. Brain Res 1293:76\u201384","journal-title":"Brain Res"},{"key":"63_CR31","doi-asserted-by":"publisher","first-page":"915","DOI":"10.1016\/j.neuroscience.2005.10.006","volume":"137","author":"R Izawa","year":"2006","unstructured":"Izawa R, Jaber M, Deroche-Gamonet V, Sillaber I, Kellendonk C, Le Moal M, Tronche F, Piazza PV (2006) Gene expression regulation following behavioral sensitization to cocaine in transgenic mice lacking the glucocorticoid receptor in the brain. Neuroscience 137:915\u2013924","journal-title":"Neuroscience"},{"key":"63_CR32","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1111\/j.1600-0447.1988.tb08565.x","volume":"345","author":"OS Jorgensen","year":"1988","unstructured":"Jorgensen OS (1988) Neural cell adhesion molecule (NCAM) and prealbumin in cerebrospinal fluid from depressed patients. Acta Psychiatr Scand Suppl 345:29\u201337","journal-title":"Acta Psychiatr Scand Suppl"},{"issue":"577\u201393","key":"63_CR33","doi-asserted-by":"publisher","first-page":"523","DOI":"10.1038\/sj.mp.4001843","volume":"11","author":"T Kasahara","year":"2006","unstructured":"Kasahara T, Kubota M, Miyauchi T, Noda Y, Mouri A, Nabeshima T, Kato T (2006) Mice with neuron-specific accumulation of mitochondrial DNA mutations show mood disorder-like phenotypes. Mol Psychiatry 11(577\u201393):523","journal-title":"Mol Psychiatry"},{"key":"63_CR34","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1111\/j.1440-1819.2007.01604.x","volume":"61","author":"T Kato","year":"2007","unstructured":"Kato T (2007) Molecular genetics of bipolar disorder and depression. Psychiatry Clin Neurosci 61:3\u201319","journal-title":"Psychiatry Clin Neurosci"},{"key":"63_CR35","doi-asserted-by":"publisher","first-page":"832","DOI":"10.1016\/j.neubiorev.2007.03.003","volume":"31","author":"T Kato","year":"2007","unstructured":"Kato T, Kubota M, Kasahara T (2007) Animal models of bipolar disorder. Neurosci Biobehav Rev 31:832\u2013842","journal-title":"Neurosci Biobehav Rev"},{"key":"63_CR36","doi-asserted-by":"crossref","unstructured":"Kim HW, Rapoport SI, Rao JS (2009) Altered expression of apoptotic factors and synaptic markers in postmortem brain from bipolar disorder patients. Neurobiol Dis 37:596\u2013603","DOI":"10.1016\/j.nbd.2009.11.010"},{"key":"63_CR37","doi-asserted-by":"publisher","first-page":"1103","DOI":"10.1016\/j.biopsych.2007.10.026","volume":"63","author":"M Lekman","year":"2008","unstructured":"Lekman M, Laje G, Charney D, Rush AJ, Wilson AF, Sorant AJ, Lipsky R, Wisniewski SR, Manji HK, McMahon FJ, Paddock S (2008) The FKBP5-gene in depression and treatment response \u2013 an association study in the sequenced treatment alternatives to relieve depression (STAR*D) cohort. Biol Psychiatry 63:1103\u20131110","journal-title":"Biol Psychiatry"},{"key":"63_CR38","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1006\/appe.1999.0274","volume":"34","author":"BT Lett","year":"2000","unstructured":"Lett BT, Grant VL, Byrne MJ, Koh MT (2000) Pairings of a distinctive chamber with the aftereffect of wheel running produce conditioned place preference. Appetite 34:87\u201394","journal-title":"Appetite"},{"key":"63_CR39","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1016\/S0091-3057(01)00722-5","volume":"72","author":"BT Lett","year":"2002","unstructured":"Lett BT, Grant VL, Koh MT, Flynn G (2002) Prior experience with wheel running produces cross-tolerance to the rewarding effect of morphine. Pharmacol Biochem Behav 72:101\u2013105","journal-title":"Pharmacol Biochem Behav"},{"key":"63_CR40","first-page":"490","volume":"60","author":"R Lien","year":"2008","unstructured":"Lien R, Flaisher-Grinberg S, Cleary C, Hejny M, Einat H (2008) Behavioral effects of Bcl-2 deficiency: implications for affective disorders. Pharmacol Rep 60:490\u2013498","journal-title":"Pharmacol Rep"},{"key":"63_CR41","doi-asserted-by":"publisher","first-page":"8766","DOI":"10.1073\/pnas.0803736105","volume":"105","author":"S Maeng","year":"2008","unstructured":"Maeng S, Hunsberger JG, Pearson B, Yuan P, Wang Y, Wei Y, McCammon J, Schloesser RJ, Zhou R, Du J, Chen G, McEwen B, Reed JC, Manji HK (2008) BAG1 plays a critical role in regulating recovery from both manic-like and depression-like behavioral impairments. Proc Natl Acad Sci USA 105:8766\u20138771","journal-title":"Proc Natl Acad Sci USA"},{"key":"63_CR42","unstructured":"Malkesman O, Scattoni ML, Paredes D, Tragon T, Pearson B, Shaltiel G, Chen G, Crawley JN, Manji HK (2009) The female urine sniffing test: a novel approach for assessing reward-seeking behavior in rodents. Biol Psychiatry124:164\u2013169"},{"key":"63_CR43","doi-asserted-by":"publisher","first-page":"807","DOI":"10.1016\/S0896-6273(02)00716-X","volume":"34","author":"C Mazzucchelli","year":"2002","unstructured":"Mazzucchelli C, Vantaggiato C, Ciamei A, Fasano S, Pakhotin P, Krezel W, Welzl H, Wolfer DP, Pages G, Valverde O, Marowsky A, Porrazzo A, Orban PC, Maldonado R, Ehrengruber MU, Cestari V, Lipp HP, Chapman PF, Pouyssegur J, Brambilla R (2002) Knockout of ERK1 MAP kinase enhances synaptic plasticity in the striatum and facilitates striatal-mediated learning and memory. Neuron 34:807\u2013820","journal-title":"Neuron"},{"key":"63_CR44","doi-asserted-by":"publisher","first-page":"637","DOI":"10.1101\/sqb.2007.72.031","volume":"72","author":"CA McClung","year":"2007","unstructured":"McClung CA (2007) Role for the Clock gene in bipolar disorder. Cold Spring Harb Symp Quant Biol 72:637\u2013644","journal-title":"Cold Spring Harb Symp Quant Biol"},{"key":"63_CR45","doi-asserted-by":"publisher","first-page":"9377","DOI":"10.1073\/pnas.0503584102","volume":"102","author":"CA McClung","year":"2005","unstructured":"McClung CA, Sidiropoulou K, Vitaterna M, Takahashi JS, White FJ, Cooper DC, Nestler EJ (2005) Regulation of dopaminergic transmission and cocaine reward by the Clock gene. Proc Natl Acad Sci USA 102:9377\u20139381","journal-title":"Proc Natl Acad Sci USA"},{"key":"63_CR46","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1037\/0735-7044.120.2.241","volume":"120","author":"AN Mead","year":"2006","unstructured":"Mead AN, Morris HV, Dixon CI, Rulten SL, Mayne LV, Zamanillo D, Stephens DN (2006) AMPA receptor GluR2, but not GluR1, subunit deletion impairs emotional response conditioning in mice. Behav Neurosci 120:241\u2013248","journal-title":"Behav Neurosci"},{"key":"63_CR47","doi-asserted-by":"publisher","first-page":"932","DOI":"10.1016\/j.neubiorev.2007.04.002","volume":"31","author":"KC O\u2019Donnell","year":"2007","unstructured":"O\u2019Donnell KC, Gould TD (2007) The behavioral actions of lithium in rodent models: leads to develop novel therapeutics. Neurosci Biobehav Rev 31:932\u2013962","journal-title":"Neurosci Biobehav Rev"},{"key":"63_CR48","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1176\/ajp.149.8.999","volume":"149","author":"RM Post","year":"1992","unstructured":"Post RM (1992) Transduction of psychosocial stress into the neurobiology of recurrent affective disorder. Am J Psychiatry 149:999\u20131010","journal-title":"Am J Psychiatry"},{"key":"63_CR49","doi-asserted-by":"publisher","first-page":"425","DOI":"10.1016\/S0278-5846(84)80031-7","volume":"8","author":"RM Post","year":"1984","unstructured":"Post RM, Weiss SR, Pert A (1984) Differential effects of carbamazepine and lithium on sensitization and kindling. Prog Neuropsychopharmacol Biol Psychiatry 8:425\u2013434","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"63_CR50","doi-asserted-by":"publisher","first-page":"9022","DOI":"10.1523\/JNEUROSCI.5216-05.2006","volume":"26","author":"J Prickaerts","year":"2006","unstructured":"Prickaerts J, Moechars D, Cryns K, Lenaerts I, van Craenendonck H, Goris I, Daneels G, Bouwknecht JA, Steckler T (2006) Transgenic mice overexpressing glycogen synthase kinase 3beta: a putative model of hyperactivity and mania. J Neurosci 26:9022\u20139029","journal-title":"J Neurosci"},{"key":"63_CR51","doi-asserted-by":"publisher","first-page":"6406","DOI":"10.1073\/pnas.0609625104","volume":"104","author":"K Roybal","year":"2007","unstructured":"Roybal K, Theobold D, Graham A, DiNieri JA, Russo SJ, Krishnan V, Chakravarty S, Peevey J, Oehrlein N, Birnbaum S, Vitaterna MH, Orsulak P, Takahashi JS, Nestler EJ, Carlezon WA Jr, McClung CA (2007) Mania-like behavior induced by disruption of CLOCK. Proc Natl Acad Sci USA 104:6406\u20136411","journal-title":"Proc Natl Acad Sci USA"},{"key":"63_CR52","doi-asserted-by":"publisher","first-page":"331","DOI":"10.1038\/sj.mp.4001949","volume":"12","author":"HG Ruhe","year":"2007","unstructured":"Ruhe HG, Mason NS, Schene AH (2007) Mood is indirectly related to serotonin, norepinephrine and dopamine levels in humans: a meta-analysis of monoamine depletion studies. Mol Psychiatry 12:331\u2013359","journal-title":"Mol Psychiatry"},{"key":"63_CR53","doi-asserted-by":"publisher","first-page":"804","DOI":"10.1016\/j.biopsych.2009.05.025","volume":"66","author":"G Salvadore","year":"2009","unstructured":"Salvadore G, Nugent AC, Chen G, Akula N, Yuan P, Cannon DM, Zarate CA Jr, McMahon FJ, Manji HK, Drevets WC (2009) Bcl-2 polymorphism influences gray matter volume in the ventral striatum in healthy humans. Biol Psychiatry 66:804\u2013807","journal-title":"Biol Psychiatry"},{"key":"63_CR54","doi-asserted-by":"publisher","first-page":"158","DOI":"10.1159\/000101535","volume":"85","author":"C Sandi","year":"2007","unstructured":"Sandi C, Bisaz R (2007) A model for the involvement of neural cell adhesion molecules in stress-related mood disorders. Neuroendocrinology 85:158\u2013176","journal-title":"Neuroendocrinology"},{"key":"63_CR55","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1101\/lm.37001","volume":"8","author":"JC Selcher","year":"2001","unstructured":"Selcher JC, Nekrasova T, Paylor R, Landreth GE, Sweatt JD (2001) Mice lacking the ERK1 isoform of MAP kinase are unimpaired in emotional learning. Learn Mem 8:11\u201319","journal-title":"Learn Mem"},{"issue":"9","key":"63_CR56","doi-asserted-by":"publisher","first-page":"858","DOI":"10.1038\/mp.2008.20","volume":"13","author":"G Shaltiel","year":"2008","unstructured":"Shaltiel G, Maeng S, Malkesman O, Pearson B, Schloesser RJ, Tragon T, Rogawski M, Gasior M, Luckenbaugh D, Chen G, Manji HK (2008) Evidence for the involvement of the kainate receptor subunit GluR6 (GRIK2) in mediating behavioral displays related to behavioral symptoms of mania. Mol Psychiatry 13(9):858\u2013872","journal-title":"Mol Psychiatry"},{"key":"63_CR57","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1523\/JNEUROSCI.3825-06.2007","volume":"27","author":"T Shinoda","year":"2007","unstructured":"Shinoda T, Taya S, Tsuboi D, Hikita T, Matsuzawa R, Kuroda S, Iwamatsu A, Kaibuchi K (2007) DISC1 regulates neurotrophin-induced axon elongation via interaction with Grb2. J Neurosci 27:4\u201314","journal-title":"J Neurosci"},{"key":"63_CR58","doi-asserted-by":"publisher","first-page":"3291","DOI":"10.1046\/j.1460-9568.2000.00197.x","volume":"12","author":"O Stork","year":"2000","unstructured":"Stork O, Welzl H, Wolfer D, Schuster T, Mantei N, Stork S, Hoyer D, Lipp H, Obata K, Schachner M (2000) Recovery of emotional behaviour in neural cell adhesion molecule (NCAM) null mutant mice through transgenic expression of NCAM180. Eur J Neurosci 12:3291\u20133306","journal-title":"Eur J Neurosci"},{"key":"63_CR59","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1126\/science.1117571","volume":"311","author":"P Svenningsson","year":"2006","unstructured":"Svenningsson P, Chergui K, Rachleff I, Flajolet M, Zhang X, El Yacoubi M, Vaugeois JM, Nomikos GG, Greengard P (2006) Alterations in 5-HT1B receptor function by p11 in depression-like states. Science 311:77\u201380","journal-title":"Science"},{"key":"63_CR60","doi-asserted-by":"publisher","first-page":"1097","DOI":"10.1002\/ajmg.b.30246","volume":"144B","author":"SJ Tsai","year":"2007","unstructured":"Tsai SJ, Hong CJ, Chen TJ, Yu YW (2007) Lack of supporting evidence for a genetic association of the FKBP5 polymorphism and response to antidepressant treatment. Am J Med Genet B Neuropsychiatr Genet 144B:1097\u20131098","journal-title":"Am J Med Genet B Neuropsychiatr Genet"},{"key":"63_CR61","doi-asserted-by":"publisher","first-page":"1937","DOI":"10.1523\/JNEUROSCI.5343-08.2009","volume":"29","author":"JL Warner-Schmidt","year":"2009","unstructured":"Warner-Schmidt JL, Flajolet M, Maller A, Chen EY, Qi H, Svenningsson P, Greengard P (2009) Role of p11 in cellular and behavioral effects of 5-HT4 receptor stimulation. J Neurosci 29:1937\u20131946","journal-title":"J Neurosci"},{"key":"63_CR62","doi-asserted-by":"publisher","first-page":"11851","DOI":"10.1073\/pnas.0402208101","volume":"101","author":"Q Wei","year":"2004","unstructured":"Wei Q, Lu XY, Liu L, Schafer G, Shieh KR, Burke S, Robinson TE, Watson SJ, Seasholtz AF, Akil H (2004) Glucocorticoid receptor overexpression in forebrain: a mouse model of increased emotional lability. Proc Natl Acad Sci USA 101:11851\u201311856","journal-title":"Proc Natl Acad Sci USA"},{"key":"63_CR63","doi-asserted-by":"crossref","first-page":"8133","DOI":"10.1523\/JNEUROSCI.22-18-08133.2002","volume":"22","author":"M Werme","year":"2002","unstructured":"Werme M, Messer C, Olson L, Gilden L, Thoren P, Nestler EJ, Brene S (2002) Delta FosB regulates wheel running. J Neurosci 22:8133\u20138138","journal-title":"J Neurosci"},{"key":"63_CR64","doi-asserted-by":"publisher","first-page":"631","DOI":"10.1038\/sj.mp.4002056","volume":"13","author":"LM Wiedholz","year":"2008","unstructured":"Wiedholz LM, Owens WA, Horton RE, Feyder M, Karlsson RM, Hefner K, Sprengel R, Celikel T, Daws LC, Holmes A (2008) Mice lacking the AMPA GluR1 receptor exhibit striatal hyperdopaminergia and \u2018schizophrenia-related\u2019 behaviors. Mol Psychiatry 13:631\u2013640","journal-title":"Mol Psychiatry"},{"key":"63_CR65","first-page":"19","volume":"49","author":"P Willner","year":"1995","unstructured":"Willner P (1995) Animal models of depression: validity and applications. Adv Biochem Psychopharmacol 49:19\u201341","journal-title":"Adv Biochem Psychopharmacol"},{"key":"63_CR66","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1007\/s002130050456","volume":"134","author":"P Willner","year":"1997","unstructured":"Willner P (1997) Validity, reliability and utility of the chronic mild stress model of depression: a 10-year review and evaluation. Psychopharmacology (Berl) 134:319\u2013329","journal-title":"Psychopharmacology (Berl)"},{"key":"63_CR67","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1097\/00008877-200205000-00001","volume":"13","author":"P Willner","year":"2002","unstructured":"Willner P, Mitchell PJ (2002) The validity of animal models of predisposition to depression. Behav Pharmacol 13:169\u2013188","journal-title":"Behav Pharmacol"},{"key":"63_CR68","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1038\/sj.mp.4002141","volume":"14","author":"VL Willour","year":"2009","unstructured":"Willour VL, Chen H, Toolan J, Belmonte P, Cutler DJ, Goes FS, Zandi PP, Lee RS, MacKinnon DF, Mondimore FM, Schweizer B, DePaulo JR, Gershon ES, McMahon FJ, Potash JB, Bipolar Disorder Phenome Group, NIMH Genetics Initiative Bipolar Disorder Consortium (2009) Family-based association of FKBP5 in bipolar disorder. Mol Psychiatry 14:261\u2013268","journal-title":"Mol Psychiatry"},{"key":"63_CR69","doi-asserted-by":"publisher","first-page":"31674","DOI":"10.1074\/jbc.M104309200","volume":"276","author":"PX Yuan","year":"2001","unstructured":"Yuan PX, Huang LD, Jiang YM, Gutkind JS, Manji HK, Chen G (2001) The mood stabilizer valproic acid activates mitogen-activated protein kinases and promotes neurite growth. J Biol Chem 276:31674\u201331683","journal-title":"J Biol Chem"},{"key":"63_CR70","unstructured":"Yuan P, Zhou R, Wang Y, Li X, Li J, Chen G, Guitart X, Manji HK (2009) Altered levels of extracellular signal-regulated kinase signaling proteins in postmortem frontal cortex of individuals with mood disorders and schizophrenia. J Affect Disord 67:864\u2013871"},{"key":"63_CR71","doi-asserted-by":"publisher","first-page":"4493","DOI":"10.1523\/JNEUROSCI.4530-04.2005","volume":"25","author":"R Zhou","year":"2005","unstructured":"Zhou R, Gray NA, Yuan P, Li X, Chen J, Chen G, Damschroder-Williams P, Du J, Zhang L, Manji HK (2005) The anti-apoptotic, glucocorticoid receptor cochaperone protein BAG-1 is a long-term target for the actions of mood stabilizers. J Neurosci 25:4493\u20134502","journal-title":"J Neurosci"}],"container-title":["Current Topics in Behavioral Neurosciences","Behavioral Neurobiology of Bipolar Disorder and its Treatment"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/7854_2010_63","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,22]],"date-time":"2025-02-22T06:59:00Z","timestamp":1740207540000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/7854_2010_63"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010]]},"ISBN":["9783642157561","9783642157578"],"references-count":71,"URL":"https:\/\/doi.org\/10.1007\/7854_2010_63","relation":{},"ISSN":["1866-3370","1866-3389"],"issn-type":[{"type":"print","value":"1866-3370"},{"type":"electronic","value":"1866-3389"}],"subject":[],"published":{"date-parts":[[2010]]},"assertion":[{"value":"26 June 2010","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}}]}}