{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,4]],"date-time":"2025-04-04T05:04:50Z","timestamp":1743743090256,"version":"3.40.3"},"publisher-location":"Berlin, Heidelberg","reference-count":111,"publisher":"Springer Berlin Heidelberg","isbn-type":[{"type":"print","value":"9783642278587"},{"type":"electronic","value":"9783642278594"}],"license":[{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011]]},"DOI":"10.1007\/7854_2011_181","type":"book-chapter","created":{"date-parts":[[2012,1,19]],"date-time":"2012-01-19T05:12:40Z","timestamp":1326949960000},"page":"615-631","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Behavioral Genetics of Neurodegenerative Disorders"],"prefix":"10.1007","author":[{"given":"Daniela","family":"Galimberti","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elio","family":"Scarpini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2012,1,20]]},"reference":[{"issue":"1","key":"181_CR1","doi-asserted-by":"crossref","first-page":"125","DOI":"10.3233\/JAD-2009-1129","volume":"18","author":"D Albani","year":"2009","unstructured":"Albani D, Prato F, Tettamanti M et al (2009) The serotonin transporter promoter polymorphic region is not a risk factor for Alzheimer\u2019s disease related behavioral disturbances. J Alzheimers Dis 18(1):125\u2013130","journal-title":"J Alzheimers Dis"},{"issue":"1","key":"181_CR2","doi-asserted-by":"crossref","first-page":"203","DOI":"10.3233\/JAD-2009-1031","volume":"17","author":"F Angelucci","year":"2009","unstructured":"Angelucci F, Bernardini S, Gravina P et al (2009). Delusion symptoms and response to antipsychotic treatment are associated with the 5-HT2A receptor polymorphism (102T\/C) in Alzheimer\u2019s disease: a 3-year follow-up longitudinal study. J Alzheimers Dis 17(1):203\u2013211","journal-title":"J Alzheimers Dis"},{"issue":"8","key":"181_CR3","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.1001\/archneur.61.8.1249","volume":"61","author":"F Assal","year":"2004","unstructured":"Assal F, Alarc\u00f3n M, Solomon EC et al (2004) Association of the serotonin transporter and receptor gene polymorphisms in neuropsychiatric symptoms in Alzheimer disease. Arch Neurol 61(8):1249\u20131253","journal-title":"Arch Neurol"},{"issue":"4","key":"181_CR4","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1093\/hmg\/8.4.711","volume":"8","author":"M Baker","year":"1999","unstructured":"Baker M, Litvan I, Houlden H et al (1999) Association of an extended haplotype in the tau gene with progressive supranuclear palsy. Hum Mol Genet 8(4):711\u2013715","journal-title":"Hum Mol Genet"},{"key":"181_CR5","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1038\/nature05016","volume":"442","author":"M Baker","year":"2006","unstructured":"Baker M, Mackenzie IR, Pickering-Brown SM et al (2006) Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17. Nature 442:916\u2013919","journal-title":"Nature"},{"key":"181_CR6","doi-asserted-by":"crossref","first-page":"2586","DOI":"10.1038\/sj.emboj.7600251","volume":"23","author":"L Baki","year":"2004","unstructured":"Baki L, Shioi J, Wen P et al (2004) PS1 activates PI3\u00a0K thus inhibiting GSK-3 activity and tau overphosphorylation: effects of FAD mutations. EMBO J 23:2586\u20132596.","journal-title":"EMBO J"},{"key":"181_CR7","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1111\/j.1471-4159.2005.03578.x","volume":"96","author":"M Bentahir","year":"2006","unstructured":"Bentahir M, Nyabi O, Verhamme J et al (2006) Presenilin clinical mutations can affect \u03b3-secretase activity by different mechanisms. J Neurochem 96:732\u2013742","journal-title":"J Neurochem"},{"issue":"5","key":"181_CR8","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1016\/j.neurobiolaging.2005.03.008","volume":"27","author":"L Bernardi","year":"2006","unstructured":"Bernardi L, Maletta RG, Tomaino C et al (2006) The effects of APOE and tau gene variability on risk of frontotemporal dementia. Neurobiol Aging 27(5):702\u2013709","journal-title":"Neurobiol Aging"},{"issue":"6","key":"181_CR9","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1172\/JCI24761","volume":"115","author":"L Bertram","year":"2005","unstructured":"Bertram L, Tanzi RE (2005) The genetic epidemiology of neurodegenerative disease. J Clin Invest 115(6):1449\u20131457","journal-title":"J Clin Invest"},{"issue":"4","key":"181_CR10","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1038\/1243","volume":"19","author":"D Blacker","year":"1998","unstructured":"Blacker D, Wilcox MA, Laird NM et al (1998) Alpha-2 macroglobulin is genetically associated with Alzheimer disease. Nat Genet 19(4):357\u2013360","journal-title":"Nat Genet"},{"key":"181_CR11","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1212\/WNL.0b013e3181d52785","volume":"74","author":"AC Bruni","year":"2010","unstructured":"Bruni AC, Bernardi L, Colao R et al (2010) Worldwide distribution of PSEN1 Met146Leu mutation. Neurology 74:798\u2013806","journal-title":"Neurology"},{"issue":"6","key":"181_CR12","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1002\/1096-8628(20001204)96:6<823::AID-AJMG26>3.0.CO;2-I","volume":"96","author":"JS Collins","year":"2000","unstructured":"Collins JS, Perry RT, Watson B Jr et al (2000) Association of a haplotype for tumor necrosis factor in siblings with late-onset Alzheimer disease: the NIMH Alzheimer Disease Genetics Initiative. Am J Med Genet 96(6):823\u2013830","journal-title":"Am J Med Genet"},{"issue":"1\u20132","key":"181_CR13","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.neulet.2004.01.035","volume":"360","author":"O Combarros","year":"2004","unstructured":"Combarros O, Infante J, Llorca J, Berciano J (2004a) No evidence for association of the monocyte chemoattractant protein-1 (\u20132518) gene polymorphism and Alzheimer\u2019s disease. Neurosci Lett 360(1-2):25\u201328","journal-title":"Neurosci Lett"},{"issue":"3","key":"181_CR14","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1016\/j.neulet.2004.05.058","volume":"366","author":"O Combarros","year":"2004","unstructured":"Combarros O, Infante J, Llorca J et al (2004b) The chemokine receptor CCR5-Delta32 gene mutation is not protective against Alzheimer\u2019s disease. Neurosci Lett 366(3):312\u2013314","journal-title":"Neurosci Lett"},{"issue":"2","key":"181_CR15","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1002\/ana.410410222","volume":"41","author":"C Conrad","year":"1997","unstructured":"Conrad C, Andreadis A, Trojanowski JQ et al (1997) Genetic evidence for the involvement of tau in progressive supranuclear palsy. Ann Neurol 41(2):277\u2013281","journal-title":"Ann Neurol"},{"issue":"5123","key":"181_CR16","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1126\/science.8346443","volume":"261","author":"EH Corder","year":"1993","unstructured":"Corder EH, Saunders AM, Strittmatter WJ et al (1993) Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer\u2019s disease in late onset families. Science 261(5123):921\u2013923","journal-title":"Science"},{"issue":"5","key":"181_CR17","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1002\/1531-8249(200005)47:5<687::AID-ANA30>3.0.CO;2-4","volume":"47","author":"F Crawford","year":"2000","unstructured":"Crawford F, Freeman M, Abdullah L et al (2000) No association between the NOS3 codon 298 polymorphism and Alzheimer\u2019s disease in a sample from the United States. Ann Neurol 47(5):687","journal-title":"Ann Neurol"},{"key":"181_CR18","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1111\/j.1749-6632.1990.tb16897.x","volume":"600","author":"AJ Cross","year":"1990","unstructured":"Cross AJ (1990) Serotonin in Alzheimer-type dementia and other dementing illnesses. Ann NY Acad Sci 600:405\u2013415","journal-title":"Ann NY Acad Sci"},{"key":"181_CR19","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1038\/nature05017","volume":"442","author":"M Cruts","year":"2006","unstructured":"Cruts M, Gijselinck I, van der Zee J et al (2006) Null mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21. Nature 442:920\u2013924","journal-title":"Nature"},{"issue":"4","key":"181_CR20","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1002\/1531-8249(199910)46:4<664::AID-ANA18>3.0.CO;2-J","volume":"46","author":"M Dahiyat","year":"1999","unstructured":"Dahiyat M, Cumming A, Harrington C et al (1999) Association between Alzheimer\u2019s disease and the NOS3 gene. Ann Neurol 46(4):664\u2013667","journal-title":"Ann Neurol"},{"issue":"3","key":"181_CR21","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1002\/1531-8249(200003)47:3<374::AID-ANA15>3.0.CO;2-8","volume":"47","author":"E Di Maria","year":"2000","unstructured":"Di Maria E, Tabaton M, Vigo T et al (2000) Corticobasal degeneration shares a common genetic background with progressive supranuclear palsy. Ann Neurol 47(3):374\u2013377","journal-title":"Ann Neurol"},{"issue":"4","key":"181_CR22","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1212\/WNL.55.4.480","volume":"55","author":"Y Du","year":"2000","unstructured":"Du Y, Dodel RC, Eastwood BJ et al (2000) Association of an interleukin 1 alpha polymorphism with Alzheimer\u2019s disease. Neurology 55(4):480\u2013483","journal-title":"Neurology"},{"key":"181_CR23","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1136\/jnnp.74.8.1148","volume":"74","author":"S Engelborghs","year":"2003","unstructured":"Engelborghs S, Dermaut B, Goeman J et al (2003) Prospective Belgian study of neurodegenerative and vascular dementia: APOE genotype effects. J Neurol Neurosurg Psychiatry 74: 1148\u20131151","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"181_CR24","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1006\/exnr.2000.7613","volume":"168","author":"SF Fabre","year":"2001","unstructured":"Fabre SF, Forsell C, Viitanen M et al (2001) Clinic-based cases with frontotemporal dementia show increased cerebrospinal fluid tau and high apolipoprotein E epsilon4 frequency, but no tau gene mutations. Exp Neurol 168:413\u2013418","journal-title":"Exp Neurol"},{"key":"181_CR25","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1006\/exnr.1995.1093","volume":"136","author":"LA Farrer","year":"1995","unstructured":"Farrer LA, Abraham CR, Volicer L et al (1995) Allele epsilon 4 of apolipoprotein E shows a dose effect on age at onset of Pick disease. Exp Neurol 136:162\u2013170","journal-title":"Exp Neurol"},{"issue":"9","key":"181_CR26","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1016\/j.neurobiolaging.2003.11.008","volume":"25","author":"C Fenoglio","year":"2004","unstructured":"Fenoglio C, Galimberti D, Lovati C et al (2004) MCP-1 in Alzheimer\u2019s disease patients: A-2518G polymorphism and serum levels. Neurobiol Aging 25(9):1169\u20131173","journal-title":"Neurobiol Aging"},{"issue":"1","key":"181_CR27","doi-asserted-by":"crossref","first-page":"171","DOI":"10.3233\/JAD-2010-1225","volume":"19","author":"D Galimberti","year":"2010","unstructured":"Galimberti D, Fenoglio C, Cortini F et al (2010) GRN variability contributes to sporadic frontotemporal lobar degeneration. J Alzheimers Dis 19(1):171\u2013177","journal-title":"J Alzheimers Dis"},{"issue":"1\u20132","key":"181_CR28","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.jns.2004.07.005","volume":"225","author":"D Galimberti","year":"2004","unstructured":"Galimberti D, Fenoglio C, Lovati C et al (2004) CCR2-64I polymorphism and CCR5Delta32 deletion in patients with Alzheimer\u2019s disease. J Neurol Sci 225(1\u20132):79\u201383","journal-title":"J Neurol Sci"},{"issue":"9","key":"181_CR29","doi-asserted-by":"crossref","first-page":"1359","DOI":"10.1016\/j.neurobiolaging.2007.03.003","volume":"29","author":"D Galimberti","year":"2008","unstructured":"Galimberti D, Scarpini E, Venturelli E et al (2008) Association of a NOS1 promoter repeat with Alzheimer\u2019s disease. Neurobiol Aging 29(9):1359\u20131365","journal-title":"Neurobiol Aging"},{"key":"181_CR30","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1007\/s00415-005-0783-2","volume":"252","author":"D Galimberti","year":"2005","unstructured":"Galimberti D, Venturelli E, Gatti A et al (2005) Association of neuronal nitric oxide synthase C276T polymorphism with Alzheimer\u2019s disease. J Neurol 252:985\u2013986","journal-title":"J Neurol"},{"issue":"1","key":"181_CR31","doi-asserted-by":"crossref","first-page":"125","DOI":"10.3233\/JAD-2009-1019","volume":"17","author":"D Galimberti","year":"2009","unstructured":"Galimberti D, Venturelli E, Villa C et al (2009) MCP-1 A-2518G polymorphism: effect on susceptibility for frontotemporal lobar degeneration and on cerebrospinal fluid MCP-1 levels. J Alzheimers Dis 17(1):125\u2013133","journal-title":"J Alzheimers Dis"},{"issue":"20","key":"181_CR32","doi-asserted-by":"crossref","first-page":"2988","DOI":"10.1093\/hmg\/ddl241","volume":"15","author":"J Gass","year":"2006","unstructured":"Gass J, Cannon A, Mackenzie IR et al (2006) Mutations in progranulin are a major cause of ubiquitin-positive frontotemporal lobar degeneration. Hum Mol Genet 15(20):2988\u20133001","journal-title":"Hum Mol Genet"},{"key":"181_CR33","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1002\/ana.410440122","volume":"44","author":"D Geschwind","year":"1998","unstructured":"Geschwind D, Karrim J, Nelson SF, Miller B (1998) The apolipoprotein E epsilon4 allele is not a significant risk factor for frontotemporal dementia. Ann Neurol 44:134\u2013138","journal-title":"Ann Neurol"},{"issue":"6311","key":"181_CR34","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1038\/349704a0","volume":"349","author":"A Goate","year":"1991","unstructured":"Goate A, Chartier-Harlin MC, Mullan M et al (1991) Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer\u2019s disease. Nature 349(6311):704\u2013706","journal-title":"Nature"},{"key":"181_CR35","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/j.bbadis.2004.08.007","volume":"1739","author":"M Goedert","year":"2005","unstructured":"Goedert M, Jakes R (2005) Mutations causing neurodegenerative tauopathies. Biochim Biophys Acta 1739:240\u2013250","journal-title":"Biochim Biophys Acta"},{"issue":"suppl","key":"181_CR36","doi-asserted-by":"crossref","first-page":"470S","DOI":"10.1093\/ajcn\/83.2.470S","volume":"83","author":"WS Griffin","year":"2006","unstructured":"Griffin WS (2006) Inflammation and neurodegenerative diseases. Am J Clin Nutr 83(suppl):470S\u2013474S","journal-title":"Am J Clin Nutr"},{"issue":"3","key":"181_CR37","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1002\/1531-8249(200003)47:3<361::AID-ANA12>3.0.CO;2-N","volume":"47","author":"LM Grimaldi","year":"2000","unstructured":"Grimaldi LM, Casadei VM, Ferri C et al (2000) Association of early-onset Alzheimer\u2019s disease with an interleukin-1alpha gene polymorphism. Ann Neurol 47(3):361\u2013365","journal-title":"Ann Neurol"},{"issue":"1","key":"181_CR38","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1086\/498851","volume":"78","author":"A Grupe","year":"2006","unstructured":"Grupe A, Li Y, Rowland C, Nowotny P et al (2006) A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. Am J Hum Genet 78(1):78\u201388","journal-title":"Am J Hum Genet"},{"issue":"6","key":"181_CR39","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1016\/j.neurobiolaging.2004.07.003","volume":"26","author":"I Guidi","year":"2005","unstructured":"Guidi I, Galimberti D, Venturelli E et al (2005) Influence of the Glu298Asp polymorphism of NOS3 on age at onset and homocysteine levels in AD patients. Neurobiol Aging 26(6):789\u2013794","journal-title":"Neurobiol Aging"},{"key":"181_CR40","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1159\/000106637","volume":"8","author":"L Gustafson","year":"1997","unstructured":"Gustafson L, Abrahamson M, Grubb A et al (1997) Apolipoprotein-E genotyping in Alzheimer\u2019s disease and frontotemporal dementia. Dement Geriatr Cogn Disord 8:240\u2013243","journal-title":"Dement Geriatr Cogn Disord"},{"issue":"1","key":"181_CR41","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1159\/000085071","volume":"20","author":"TM Ha","year":"2005","unstructured":"Ha TM, Cho DM, Park SW, Joo MJ, Lee BJ, Kong BG, Kim JM, Yoon JS, Kim YH (2005) Evaluating associations between 5-HTTLPR polymorphism and Alzheimer\u2019s disease for Korean patients. Dement Geriatr Cogn Disord 20(1):31\u201334","journal-title":"Dement Geriatr Cogn Disord"},{"issue":"5580","key":"181_CR42","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1126\/science.1072994","volume":"297","author":"J Hardy","year":"2002","unstructured":"Hardy J, Selkoe DJ (2002) The amyloid hypothesis of Alzheimer\u2019s disease: progress and problems on the road to therapeutics. Science 297(5580):353\u2013356","journal-title":"Science"},{"issue":"10","key":"181_CR43","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1038\/ng.440","volume":"41","author":"D Harold","year":"2009","unstructured":"Harold D, Abraham R, Hollingworth P et al (2009) Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer\u2019s disease. Nat Genet 41(10):1088\u20131093","journal-title":"Nat Genet"},{"key":"181_CR44","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1007\/s00109-003-0474-3","volume":"81","author":"Z He","year":"2003","unstructured":"He Z, Bateman A (2003) Progranulin (granulin-epithelin precursor, PC-cell-derived growth factor, acrogranin) mediates tissue repair and tumorigenesis. J Mol Med 81:600\u2013612","journal-title":"J Mol Med"},{"key":"181_CR45","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/0304-3940(96)12373-9","volume":"205","author":"S Helisalmi","year":"1996","unstructured":"Helisalmi S, Linnaranta K, Lehtovirta M et al (1996) Apolipoprotein E polymorphism in patients with different neurodegenerative disorders. Neurosci Lett 205:61\u201364","journal-title":"Neurosci Lett"},{"key":"181_CR46","doi-asserted-by":"crossref","first-page":"1664","DOI":"10.1001\/jama.284.13.1664","volume":"284","author":"BA Hosler","year":"2000","unstructured":"Hosler BA, Siddique T, Sapp PC et al (2000) Linkage of familial amyotrophic lateral sclerosis with frontotemporal dementia to chromosome 9q21\u2212q22. JAMA 284:1664\u20131669","journal-title":"JAMA"},{"issue":"3","key":"181_CR47","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1177\/070674370404900303","volume":"49","author":"CE Hou","year":"2004","unstructured":"Hou CE, Carlin D, Miller BL (2004) Non-Alzheimer\u2019s disease dementias: anatomic, clinical, and molecular correlates. Can J Psychiatry 49(3):164\u2013171","journal-title":"Can J Psychiatry"},{"issue":"2\u20133","key":"181_CR48","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.neulet.2004.08.016","volume":"370","author":"C Huerta","year":"2004","unstructured":"Huerta C, Alvarez V, Mata IF et al (2004) Chemokines (RANTES and MCP-1) and chemokine-receptors (CCR2 and CCR5) gene polymorphisms in Alzheimer\u2019s and Parkinson\u2019s disease. Neurosci Lett 370(2\u20133):151\u2013154","journal-title":"Neurosci Lett"},{"key":"181_CR49","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1016\/j.devcel.2005.02.019","volume":"8","author":"SS Huppert","year":"2005","unstructured":"Huppert SS, Ilagan MX, De Strooper B, Kopan R (2005) Analysis of Notch function in presomitic mesoderm suggests a \u03b3-secretase-independent role for presenilins in somite differentiation. Dev Cell 8:677\u2013688","journal-title":"Dev Cell"},{"key":"181_CR50","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1038\/31508","volume":"393","author":"M Hutton","year":"1998","unstructured":"Hutton M, Lendon CL, Rizzu P et al (1998) Association of missense and 5\u2032-splice-site mutations in tau with the inherited dementia FTDP-17. Nature 393:702\u2013705","journal-title":"Nature"},{"issue":"10","key":"181_CR51","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.1038\/ng.439","volume":"41","author":"JC Lambert","year":"2009","unstructured":"Lambert JC, Heath S, Even G et al (2009) Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer\u2019s disease. Nat Genet 41(10):1094\u20131099","journal-title":"Nat Genet"},{"issue":"2","key":"181_CR52","doi-asserted-by":"crossref","first-page":"259","DOI":"10.3233\/JAD-2009-1042","volume":"17","author":"AJ Larner","year":"2009","unstructured":"Larner AJ, Doran M (2009) Genotype-phenotype relationships of presenilin-1 mutations in Alzheimer\u2019s disease: an update. J Alzheimers Dis 17(2):259\u2013265","journal-title":"J Alzheimers Dis"},{"key":"181_CR53","doi-asserted-by":"crossref","first-page":"1669","DOI":"10.1212\/WNL.0b013e3181a55f1c","volume":"72","author":"I Le Ber","year":"2009","unstructured":"Le Ber I, Camuzat A, Berger E et al (2009) Chromosome 9p-linked families with frontotemporal dementia associated with motor neuron disease. Neurology 72:1669\u20131676","journal-title":"Neurology"},{"key":"181_CR54","doi-asserted-by":"crossref","first-page":"1546","DOI":"10.1212\/WNL.50.6.1546","volume":"50","author":"CL Lendon","year":"1998","unstructured":"Lendon CL, Lynch T, Norton J et al (1998) Hereditary dysphasic disinhibition dementia: a frontotemporal dementia linked to 17q21\u201322. Neurology 50:1546\u20131555","journal-title":"Neurology"},{"issue":"2","key":"181_CR55","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1007\/BF01276434","volume":"95","author":"KP Lesch","year":"1994","unstructured":"Lesch KP, Balling U, Gross J et al (1994) Organization of the human serotonin transporter gene. J Neural Transm Gen Sect 95(2):157\u2013162","journal-title":"J Neural Transm Gen Sect"},{"issue":"5226","key":"181_CR56","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1126\/science.7638622","volume":"269","author":"E Levy-Lahad","year":"1995","unstructured":"Levy-Lahad E, Wasco W, Poorkaj P et al (1995) Candidate gene for the chromosome 1 familial Alzheimer\u2019s disease locus. Science 269(5226):973\u2013977","journal-title":"Science"},{"issue":"17","key":"181_CR57","doi-asserted-by":"crossref","first-page":"2560","DOI":"10.1093\/hmg\/ddl178","volume":"15","author":"Y Li","year":"2006","unstructured":"Li Y, Grupe A, Rowland C et al (2006) DAPK1 variants are associated with Alzheimer\u2019s disease and allele-specific expression. Hum Mol Genet 15(17):2560\u20132568","journal-title":"Hum Mol Genet"},{"key":"181_CR58","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1016\/S0047-6374(03)00034-4","volume":"124","author":"F Licastro","year":"2003","unstructured":"Licastro F, Chiappelli M (2003) Brain immune responses cognitive decline and dementia: relationship with phenotype expression and genetic background. Mech Ageing Dev 124:539\u2013548","journal-title":"Mech Ageing Dev"},{"key":"181_CR59","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1002\/ajmg.10670","volume":"114","author":"YJ Liou","year":"2002","unstructured":"Liou YJ, Hong CJ, Liu HC et al (2002) No association between the neuronal nitric oxide synthase gene polymorphism and Alzheimer\u2019s disease. Am J Med Gen 114:687\u2013688","journal-title":"Am J Med Gen"},{"issue":"3","key":"181_CR60","doi-asserted-by":"crossref","first-page":"153","DOI":"10.2165\/00129785-200101030-00001","volume":"1","author":"FE Lotrich","year":"2001","unstructured":"Lotrich FE, Pollock BG, Ferrell RE (2001) Polymorphism of the serotonin transporter: implications for the use of selective serotonin reuptake inhibitors. Am J Pharmacogenomics 1(3):153\u2013164","journal-title":"Am J Pharmacogenomics"},{"key":"181_CR61","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1093\/brain\/awh724","volume":"129","author":"IR Mackenzie","year":"2006","unstructured":"Mackenzie IR, Baker M, West G et al (2006) A family with tau-negative frontotemporal dementia and neuronal intranuclear inclusions linked to chromosome 17. Brain 129:853\u2013867","journal-title":"Brain"},{"key":"181_CR62","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/S0304-3940(03)00210-6","volume":"341","author":"R Monastero","year":"2003","unstructured":"Monastero R, Cefalu AB, Camarda C et al (2003) No association between Glu298Asp endothelial nitric oxide synthase polymorphism and Italian sporadic Alzheimer\u2019s disease. Neurosci Lett 341:229\u2013232","journal-title":"Neurosci Lett"},{"issue":"6","key":"181_CR63","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1212\/01.wnl.0000200048.53766.b4","volume":"66","author":"M Morita","year":"2006","unstructured":"Morita M, Al-Chalabi A, Andersen PM et al (2006) A locus on chromosome 9p confers susceptibility to ALS and frontotemporal dementia. Neurology 66(6):839\u2013844","journal-title":"Neurology"},{"key":"181_CR64","doi-asserted-by":"crossref","first-page":"1546","DOI":"10.1212\/WNL.51.6.1546","volume":"51","author":"D Neary","year":"1998","unstructured":"Neary D, Snowden JS, Gustafson L et al (1998) Frontotemporal lobar degeneration: a consensus on clinical diagnostic criteria. Neurology 51:1546\u20131554","journal-title":"Neurology"},{"key":"181_CR65","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1126\/science.1134108","volume":"314","author":"M Neumann","year":"2006","unstructured":"Neumann M, Sampathu DM, Kwong LK et al (2006) Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Science 314:130\u2013133","journal-title":"Science"},{"issue":"3","key":"181_CR66","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1002\/1531-8249(200003)47:3<365::AID-ANA13>3.0.CO;2-G","volume":"47","author":"JA Nicoll","year":"2000","unstructured":"Nicoll JA, Mrak RE, Graham DI et al (2000) Association of interleukin-1 gene polymorphisms with Alzheimer\u2019s disease. Ann Neurol 47(3):365\u2013368","journal-title":"Ann Neurol"},{"key":"181_CR67","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1006\/neur.1996.0051","volume":"5","author":"AM Palmer","year":"1996","unstructured":"Palmer AM (1996) Neurochemical studies of Alzheimer\u2019s disease. Neurodegeneration 5:381\u2013391","journal-title":"Neurodegeneration"},{"issue":"5","key":"181_CR68","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1002\/1531-8249(199905)45:5<666::AID-ANA18>3.0.CO;2-3","volume":"45","author":"A Papassotiropoulos","year":"1999","unstructured":"Papassotiropoulos A, Bagli M, Jessen F et al (1999) A genetic variation of the inflammatory cytokine interleukin-6 delays the initial onset and reduces the risk for sporadic Alzheimer\u2019s disease. Ann Neurol 45(5):666-668","journal-title":"Ann Neurol"},{"issue":"6","key":"181_CR69","first-page":"1034","volume":"48","author":"MA Pericak-Vance","year":"1991","unstructured":"Pericak-Vance MA, Bebout JL, Gaskell PC Jr et al (1991) Linkage studies in familial Alzheimer disease: evidence for chromosome 19 linkage. Am J Hum Genet 48(6):1034\u20131050","journal-title":"Am J Hum Genet"},{"issue":"2","key":"181_CR70","doi-asserted-by":"crossref","first-page":"R156","DOI":"10.1093\/hmg\/ddp303","volume":"18","author":"G Pesiridis","year":"2009","unstructured":"Pesiridis G, Lee VMY, Trojanowski JQ (2009) Mutations in TDP-43 link glycine-rich domain functions to amyotrophic lateral sclerosis. Hum Mol Gen 18(2):R156\u2013162","journal-title":"Hum Mol Gen"},{"key":"181_CR71","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1002\/ana.410430617","volume":"43","author":"P Poorkaj","year":"1998","unstructured":"Poorkaj P, Bird TD, Wijsman E et al (1998) Tau is a candidate gene for chromosome 17 frontotemporal dementia. Ann Neurol 43:815\u2013825","journal-title":"Ann Neurol"},{"issue":"5","key":"181_CR72","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1016\/j.neurobiolaging.2003.12.023","volume":"25","author":"J Raber","year":"2004","unstructured":"Raber J, Huang Y, Ashford JW (2004) ApoE genotype accounts for the vast majority of AD risk and AD pathology. Neurobiol Aging 25(5):641\u2013650","journal-title":"Neurobiol Aging"},{"key":"181_CR73","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.1038\/sj.mp.4001198","volume":"7","author":"R Rademakers","year":"2002","unstructured":"Rademakers R, Cruts M, Dermaut B et al (2002) Tau negative frontal lobe dementia at 17q21: significant finemapping of the candidate region to a 4.8\u00a0cM interval. Mol Psychiatry 7:1064\u20131074","journal-title":"Mol Psychiatry"},{"issue":"4","key":"181_CR74","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1002\/humu.20086","volume":"24","author":"R Rademakers","year":"2004","unstructured":"Rademakers R, Cruts M, van Broeckhoven C (2004) The role of tau (MAPT) in frontotemporal dementia and related tauopathies. Hum Mutat 24(4):277\u2013295","journal-title":"Hum Mutat"},{"issue":"3","key":"181_CR76","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1038\/sj.mp.4001779","volume":"11","author":"A Reif","year":"2006","unstructured":"Reif A, Herterich S, Strobel A et al (2006) A neuronal nitric oxide synthase (NOS-I) haplotype associated with schizophrenia modifies prefrontal cortex function. Mol Psychiatry 11(3):286\u2013300","journal-title":"Mol Psychiatry"},{"issue":"4","key":"181_CR77","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1002\/jnr.490270419","volume":"27","author":"KJ Reinikainen","year":"1990","unstructured":"Reinikainen KJ, Soininen H, Riekkinen PJ (1990) Neurotransmitter changes in Alzheimer\u2019s disease: implications to diagnostics and therapy. J Neurosci Res 27(4):576\u2013586","journal-title":"J Neurosci Res"},{"key":"181_CR78","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1136\/jnnp.72.5.639","volume":"72","author":"M Riemenschneider","year":"2002","unstructured":"Riemenschneider M, Diehl J, Muller U et al (2002) Apolipoprotein E polymorphism in German patients with frontotemporal degeneration. J Neurol Neurosurg Psychiatry 72:639\u2013641","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"4","key":"181_CR79","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1089\/109065703322783662","volume":"7","author":"A Rocchi","year":"2003","unstructured":"Rocchi A, Micheli D, Ceravolo R et al (2003) Serotoninergic polymorphisms (5-HTTLPR and 5-HT2A): association studies with psychosis in Alzheimer disease. Genet Test 7(4):309\u2013314","journal-title":"Genet Test"},{"key":"181_CR80","doi-asserted-by":"crossref","first-page":"1608","DOI":"10.1212\/WNL.58.11.1608","volume":"58","author":"HJ Rosen","year":"2002","unstructured":"Rosen HJ, Hartikainen KM, Jagust W et al (2002) Utility of clinical criteria in differentiating frontotemporal lobar degeneration (FTLD) from AD. Neurology 58:1608\u20131615","journal-title":"Neurology"},{"key":"181_CR81","doi-asserted-by":"crossref","first-page":"1948","DOI":"10.1093\/brain\/124.10.1948","volume":"124","author":"SM Rosso","year":"2001","unstructured":"Rosso SM, Kamphorst W, de Graaf B et al (2001) Familial frontotemporal dementia with ubiquitin-positive inclusions is linked to chromosome 17q21\u201322. Brain 124:1948\u20131957","journal-title":"Brain"},{"key":"181_CR82","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1038\/ng1718","volume":"38","author":"A Rovelet-Lecrux","year":"2006","unstructured":"Rovelet-Lecrux A, Hannequin D, Raux G et al (2006) APP locus duplication causes autosomal dominant early-onset Alzheimer disease with cerebral amyloid angiopathy. Nat Genet 38:24\u201326","journal-title":"Nat Genet"},{"key":"181_CR83","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1136\/jnnp.70.4.566","volume":"70","author":"M S\u00e1nchez-Guerra","year":"2001","unstructured":"S\u00e1nchez-Guerra M, Combarros O, Alvarez-Arcaya A et al (2001) The Glu298Asp polymorphism in the NOS3 gene is not associated with sporadic Alzheimer\u2019s disease. J Neurol Neurosurg Psychiatry 70:566\u2013567","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"2","key":"181_CR84","doi-asserted-by":"crossref","first-page":"441","DOI":"10.3233\/JAD-2009-1054","volume":"17","author":"N Sato","year":"2009","unstructured":"Sato N, Ueki A, Ueno H et al (2009) Dopamine D3 receptor gene polymorphism influences on behavioral and psychological symptoms of dementia (BPSD) in mild dementia of Alzheimer\u2019s type. J Alzheimers Dis 17(2):441\u2013448","journal-title":"J Alzheimers Dis"},{"issue":"6","key":"181_CR85","doi-asserted-by":"crossref","first-page":"1662","DOI":"10.1073\/pnas.0305473101","volume":"101","author":"D Saur","year":"2004","unstructured":"Saur D, Vanderwinden JM, Seidler B et al (2004) Single-nucleotide promoter polymorphism alters transcription of neuronal nitric oxide synthase exon 1c in infantile hypertrophic pyloric stenosis. Proc Natl Acad Sci 101(6):1662\u20131667","journal-title":"Proc Natl Acad Sci"},{"issue":"1\u20132","key":"181_CR86","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.jns.2005.09.006","volume":"240","author":"E Scarpini","year":"2006","unstructured":"Scarpini E, Galimberti D, Guidi I et al (2006) Progressive, isolated language disturbance: its significance in a 65-year-old-man. A case report with implications for treatment and review of literature. J Neurol Sci 240(1\u20132):45\u201351","journal-title":"J Neurol Sci"},{"key":"181_CR87","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1056\/NEJMoa011613","volume":"346","author":"S Seshadri","year":"2002","unstructured":"Seshadri S, Beiser A, Selhub J et al (2002) Plasma homocysteine as a risk factor for dementia and Alzheimer\u2019s disease. New Engl J Med 346:476-483","journal-title":"New Engl J Med"},{"issue":"6534","key":"181_CR88","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1038\/375754a0","volume":"375","author":"R Sherrington","year":"1995","unstructured":"Sherrington R, Rogaev EI, Liang Y et al (1995) Cloning of a gene bearing missense mutations in early-onset familial Alzheimer\u2019s disease. Nature 375(6534):754\u2013760","journal-title":"Nature"},{"key":"181_CR89","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1001\/archneur.59.4.611","volume":"59","author":"RA Short","year":"2002","unstructured":"Short RA, Graff-Radford NR, Adamson J et al (2002) Differences in tau and apolipoprotein E polymorphism frequencies in sporadic frontotemporal lobar degeneration syndromes. Arch Neurol 59:611\u2013615","journal-title":"Arch Neurol"},{"key":"181_CR90","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1038\/ng1609","volume":"37","author":"G Skibinski","year":"2005","unstructured":"Skibinski G, Parkinson NJ, Brown JM et al (2005) Mutations in the endosomal ESCRTIII-complex subunit CHMP2B in frontotemporal dementia. Nat Genet 37:806\u2013808","journal-title":"Nat Genet"},{"key":"181_CR91","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1192\/bjp.180.2.140","volume":"180","author":"JS Snowden","year":"2002","unstructured":"Snowden JS, Neary D, Mann DM (2002) Frontotemporal dementia. Br J Psychiatry 180:140\u2013143","journal-title":"Br J Psychiatry"},{"key":"181_CR92","doi-asserted-by":"crossref","first-page":"3091","DOI":"10.1093\/brain\/awl267","volume":"129","author":"JS Snowden","year":"2006","unstructured":"Snowden JS, Pickering-Brown SM, Mackenzie IR et al (2006) Progranulin gene mutations associated with frontotemporal dementia and progressive non-fluent aphasia. Brain 129:3091\u20133102","journal-title":"Brain"},{"key":"181_CR93","doi-asserted-by":"crossref","first-page":"7737","DOI":"10.1073\/pnas.95.13.7737","volume":"95","author":"MG Spillantini","year":"1998","unstructured":"Spillantini MG, Murrell JR, Goedert M et al (1998) Mutation in the tau gene in familial multiple system tauopathy with presenile dementia. Proc Natl Acad Sci USA 95:7737\u20137741","journal-title":"Proc Natl Acad Sci USA"},{"key":"181_CR94","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1136\/jnnp.2005.063966","volume":"77","author":"R Srinivasan","year":"2006","unstructured":"Srinivasan R, Davidson Y, Gibbons L et al (2006) The apolipoprotein E epsilon4 allele selectively increases the risk of frontotemporal lobar degeneration in males. J Neurol Neurosurg Psychiatry 77:154\u2013158","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"181_CR95","doi-asserted-by":"crossref","first-page":"7615","DOI":"10.1074\/jbc.274.12.7615","volume":"274","author":"H Steiner","year":"1999","unstructured":"Steiner H, Romig H, Grim MG et al (1999) The biological and pathological function of the presenilin-1 dExon 9 mutation is independent of its defect to undergo proteolytic processing. J Biol Chem 274:7615\u20137618","journal-title":"J Biol Chem"},{"key":"181_CR96","doi-asserted-by":"crossref","first-page":"1526","DOI":"10.1212\/WNL.48.6.1526","volume":"48","author":"M Stevens","year":"1997","unstructured":"Stevens M, van Duijn CM, de Knijff P et al (1997) Apolipoprotein E gene and sporadic frontal lobe dementia. Neurology 48:1526\u20131529","journal-title":"Neurology"},{"issue":"9","key":"181_CR97","doi-asserted-by":"crossref","first-page":"1425","DOI":"10.1001\/archneur.58.9.1425","volume":"58","author":"DL Sukonick","year":"2001","unstructured":"Sukonick DL, Pollock BG, Sweet RA et al (2001) The 5-HTTPR*S\/*L polymorphism and aggressive behavior in Alzheimer disease. Arch Neurol 58(9):1425\u20131428","journal-title":"Arch Neurol"},{"issue":"4","key":"181_CR98","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1017\/S1041610201007827","volume":"13","author":"RA Sweet","year":"2001","unstructured":"Sweet RA, Pollock BG, Sukonick DL et al (2001) The 5-HTTPR polymorphism confers liability to a combined phenotype of psychotic and aggressive behavior in Alzheimer disease. Int Psychogeriatr 13(4):401\u2013409","journal-title":"Int Psychogeriatr"},{"issue":"4791","key":"181_CR99","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1126\/science.2949367","volume":"235","author":"RE Tanzi","year":"1987","unstructured":"Tanzi RE, Gusella JF et al (1987) Amyloid beta protein gene: cDNA, mRNA distribution, and genetic linkage near the Alzheimer locus. Science 235(4791):880\u2013884","journal-title":"Science"},{"key":"181_CR100","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1007\/PL00007839","volume":"249","author":"A Tedde","year":"2002","unstructured":"Tedde A, Nacmias B, Cellini E et al (2002) Lack of association between NOS3 polymorphism and Italian sporadic and familial Alzheimer\u2019s disease. J Neurol 249:110\u2013111","journal-title":"J Neurol"},{"issue":"3","key":"181_CR101","doi-asserted-by":"crossref","first-page":"245","DOI":"10.3233\/JAD-2007-12306","volume":"12","author":"A Ueki","year":"2007","unstructured":"Ueki A, Ueno H, Sato N, Shinjo H, Morita Y (2007) Serotonin transporter gene polymorphism and BPSD in mild Alzheimer\u2019s disease. J Alzheimers Dis 12(3):245\u2013253","journal-title":"J Alzheimers Dis"},{"key":"181_CR102","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1093\/brain\/awl029","volume":"129","author":"J van der Zee","year":"2006","unstructured":"van der Zee J, Rademakers R, Engelborghs S et al (2006) A Belgian ancestral haplotype harbours a highly prevalent mutation for 17q21-linked tau-negative FTLD. Brain 129:841\u2013852","journal-title":"Brain"},{"key":"181_CR103","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1093\/brain\/awl030","volume":"129","author":"C Vance","year":"2006","unstructured":"Vance C, Al-Chalabi A, Ruddy D et al (2006) Familial amyotrophic lateral sclerosis with frontotemporal dementia is linked to a locus on chromosome 9p13.2\u201321.3. Brain 129:868\u2013876","journal-title":"Brain"},{"issue":"1\u20132","key":"181_CR104","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.neulet.2006.05.054","volume":"404","author":"E Venturelli","year":"2006","unstructured":"Venturelli E, Galimberti D, Fenoglio C et al (2006) Candidate gene analysis of IP-10 gene in patients with Alzheimer\u2019s disease. Neurosci Lett 404(1\u20132):217\u2013221","journal-title":"Neurosci Lett"},{"issue":"3","key":"181_CR105","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/j.neulet.2005.03.032","volume":"382","author":"E Venturelli","year":"2005","unstructured":"Venturelli E, Galimberti D, Lovati C et al (2005) The T-786C NOS3 polymorphism in Alzheimer\u2019s disease: association and influence on gene expression. Neurosci Lett 382(3):300\u2013303","journal-title":"Neurosci Lett"},{"issue":"1","key":"181_CR106","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1111\/j.1468-1331.2008.02335.x","volume":"16","author":"E Venturelli","year":"2009","unstructured":"Venturelli E, Villa C, Fenoglio C et al (2009) The NOS3 G894T (Glu298Asp) polymorphism is a risk factor for frontotemporal lobar degeneration. Eur J Neurol 16(1):37\u201342","journal-title":"Eur J Neurol"},{"issue":"1","key":"181_CR107","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1111\/j.1468-1331.2007.02007.x","volume":"15","author":"E Venturelli","year":"2008","unstructured":"Venturelli E, Villa C, Scarpini E et al (2008) Neuronal nitric oxide synthase C276T polymorphism increases the risk for frontotemporal lobar degeneration. Eur J Neurol 15(1):77\u201381","journal-title":"Eur J Neurol"},{"key":"181_CR108","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1038\/sj.ejhg.5200820","volume":"10","author":"P Verpillat","year":"2002","unstructured":"Verpillat P, Camuzat A, Hannequin D et al (2002) Apolipoprotein E gene in frontotemporal dementia: an association study and meta-analysis. Eur J Hum Genet 10:399\u2013405","journal-title":"Eur J Hum Genet"},{"issue":"21","key":"181_CR109","doi-asserted-by":"crossref","first-page":"121505","DOI":"10.1073\/pnas.96.21.12150","volume":"96","author":"Y Wang","year":"1999","unstructured":"Wang Y, Newton DC, Robb GB et al (1999) RNA diversity has profound effects on the translation of neuronal nitric oxide synthase. Proc Natl Acad Sci USA 96(21):121505\u201312155","journal-title":"Proc Natl Acad Sci USA"},{"key":"181_CR110","first-page":"1159","volume":"55","author":"KC Wilhelmsen","year":"1994","unstructured":"Wilhelmsen KC, Lynch T, Pavlou E et al (1994) Localization of disinhibition\u2013dementia\u2013parkinsonism\u2013amyotrophy complex to 17q21\u201322. Am J Hum Genet 55:1159\u20131165","journal-title":"Am J Hum Genet"},{"issue":"2","key":"181_CR111","first-page":"161","volume":"67","author":"CE Yu","year":"2010","unstructured":"Yu CE, Bird TD, Bekris LM et al (2010) The spectrum of mutations in progranulin: a collaborative study screening 545 cases of neurodegeneration. Arch Neurol 67(2):161\u2013170","journal-title":"Arch Neurol"},{"key":"181_CR112","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1016\/S0092-8674(02)01141-8","volume":"111","author":"J Zhu","year":"2002","unstructured":"Zhu J, Nathan C, Jin W et al (2002) Conversion of proepithelin to epithelins: roles of SLPI and elastase in host defence and wound repair. Cell 111:867\u2013878","journal-title":"Cell"}],"container-title":["Current Topics in Behavioral Neurosciences","Behavioral Neurogenetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/7854_2011_181","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,18]],"date-time":"2024-04-18T00:16:36Z","timestamp":1713399396000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/7854_2011_181"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011]]},"ISBN":["9783642278587","9783642278594"],"references-count":111,"URL":"https:\/\/doi.org\/10.1007\/7854_2011_181","relation":{},"ISSN":["1866-3370","1866-3389"],"issn-type":[{"type":"print","value":"1866-3370"},{"type":"electronic","value":"1866-3389"}],"subject":[],"published":{"date-parts":[[2011]]},"assertion":[{"value":"20 January 2012","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}}]}}