{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T10:28:31Z","timestamp":1790677711924,"version":"4.1.0"},"publisher-location":"Cham","reference-count":76,"publisher":"Springer International Publishing","isbn-type":[{"value":"9783031096822","type":"print"},{"value":"9783031096839","type":"electronic"}],"license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022]]},"DOI":"10.1007\/7854_2022_352","type":"book-chapter","created":{"date-parts":[[2022,4,18]],"date-time":"2022-04-18T14:03:48Z","timestamp":1650290628000},"page":"255-277","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Anhedonia in Neurodegenerative Diseases"],"prefix":"10.1007","author":[{"given":"Vicky","family":"Turner","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masud","family":"Husain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,4,19]]},"reference":[{"key":"352_CR1","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1159\/000110738","volume":"24","author":"P Aalten","year":"2007","unstructured":"Aalten P, Verhey FRJ, Boziki M et al (2007) Neuropsychiatric syndromes in dementia. Dement Geriatr Cogn Disord 24:457\u2013463","journal-title":"Dement Geriatr Cogn Disord"},{"key":"352_CR2","doi-asserted-by":"publisher","first-page":"1222","DOI":"10.1212\/01.WNL.0000156519.41681.27","volume":"64","author":"S Abrahams","year":"2005","unstructured":"Abrahams S, Leigh PN, Goldstein LH (2005) Cognitive change in ALS: a prospective study. Neurology 64:1222\u20131226","journal-title":"Neurology"},{"key":"352_CR3","doi-asserted-by":"publisher","first-page":"e0169938","DOI":"10.1371\/journal.pone.0169938","volume":"12","author":"Y-S Ang","year":"2017","unstructured":"Ang Y-S, Lockwood P, Apps MAJ et al (2017) Distinct subtypes of apathy revealed by the apathy motivation index. PLoS One 12:e0169938","journal-title":"PLoS One"},{"key":"352_CR4","doi-asserted-by":"publisher","first-page":"1286","DOI":"10.1002\/acn3.626","volume":"5","author":"YS Ang","year":"2018","unstructured":"Ang YS, Lockwood PL, Kienast A et al (2018) Differential impact of behavioral, social, and emotional apathy on Parkinson\u2019s disease. Ann Clin Transl Neurol 5:1286\u20131291","journal-title":"Ann Clin Transl Neurol"},{"key":"352_CR5","doi-asserted-by":"publisher","first-page":"342","DOI":"10.1016\/j.jns.2017.02.020","volume":"375","author":"A Antosik-W\u00f3jci\u0144ska","year":"2017","unstructured":"Antosik-W\u00f3jci\u0144ska A, \u015awi\u0119cicki \u0141, Dominiak M et al (2017) Impact of STN-DBS on mood, drive, anhedonia and risk of psychiatric side-effects in the population of PD patients. J Neurol Sci 375:342\u2013347","journal-title":"J Neurol Sci"},{"key":"352_CR6","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1016\/B978-0-12-804766-8.00016-9","volume":"167","author":"MJ Armstrong","year":"2019","unstructured":"Armstrong MJ, McFarland N (2019) Recognizing and treating atypical Parkinson disorders. Handb Clin Neurol 167:301\u2013320","journal-title":"Handb Clin Neurol"},{"key":"352_CR7","doi-asserted-by":"publisher","first-page":"1825","DOI":"10.1002\/mds.23815","volume":"26","author":"F Assogna","year":"2011","unstructured":"Assogna F, Cravello L, Caltagirone C, Spalletta G (2011) Anhedonia in Parkinson\u2019s disease: a systematic review of the literature. Mov Disord 26:1825\u20131834","journal-title":"Mov Disord"},{"key":"352_CR8","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1002\/brb3.1448","volume":"9","author":"F Assogna","year":"2019","unstructured":"Assogna F, Pellicano C, Cravello L et al (2019) Alexithymia and anhedonia in early Richardson\u2019s syndrome and progressive supranuclear palsy with predominant parkinsonism. Brain Behav 9:3\u20139","journal-title":"Brain Behav"},{"key":"352_CR9","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1016\/S1474-4422(10)70106-X","volume":"9","author":"P Barone","year":"2010","unstructured":"Barone P, Poewe W, Albrecht S et al (2010) Pramipexole for the treatment of depressive symptoms in patients with Parkinson\u2019s disease: a randomised, double-blind, placebo-controlled trial. Lancet Neurol 9:573\u2013580","journal-title":"Lancet Neurol"},{"key":"352_CR10","doi-asserted-by":"publisher","first-page":"294","DOI":"10.1016\/j.conb.2013.01.017","volume":"23","author":"KC Berridge","year":"2013","unstructured":"Berridge KC, Kringelbach ML (2013) Neuroscience of affect: brain mechanisms of pleasure and displeasure. Curr Opin Neurobiol 23:294\u2013303","journal-title":"Curr Opin Neurobiol"},{"key":"352_CR11","doi-asserted-by":"publisher","first-page":"646","DOI":"10.1016\/j.neuron.2015.02.018","volume":"86","author":"KC Berridge","year":"2015","unstructured":"Berridge KC, Kringelbach ML (2015) Pleasure systems in the brain. Neuron 86:646\u2013664","journal-title":"Neuron"},{"key":"352_CR12","doi-asserted-by":"publisher","first-page":"507","DOI":"10.1016\/S0166-2236(03)00233-9","volume":"26","author":"KC Berridge","year":"2003","unstructured":"Berridge KC, Robinson TE (2003) Parsing reward. Trends Neurosci 26:507\u2013513","journal-title":"Trends Neurosci"},{"key":"352_CR13","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1176\/appi.psy.50.3.239","volume":"50","author":"DM Blass","year":"2009","unstructured":"Blass DM, Rabins PV (2009) Depression in frontotemporal dementia. Psychosomatics 50:239\u2013247","journal-title":"Psychosomatics"},{"key":"352_CR14","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1080\/14660820510037863","volume":"6","author":"C Bungener","year":"2005","unstructured":"Bungener C, Piquard A, Pradat PF et al (2005) Psychopathology in amyotrophic lateral sclerosis: a preliminary study with 27 ALS patients. Amyotroph Lateral Scler Other Mot Neuron Disord 6:221\u2013225","journal-title":"Amyotroph Lateral Scler Other Mot Neuron Disord"},{"key":"352_CR15","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1037\/0021-843X.85.4.374","volume":"85","author":"LJ Chapman","year":"1976","unstructured":"Chapman LJ, Chapman JP, Raulin ML (1976) Scales for physical and social anhedonia. J Abnorm Psychol 85:374\u2013382","journal-title":"J Abnorm Psychol"},{"key":"352_CR16","doi-asserted-by":"publisher","first-page":"e0179399","DOI":"10.1371\/journal.pone.0179399","volume":"12","author":"PY Chiu","year":"2017","unstructured":"Chiu PY, Wang CW, Tsai CT et al (2017) Depression in dementia with Lewy bodies: a comparison with Alzheimer\u2019s disease. PLoS One 12:e0179399","journal-title":"PLoS One"},{"key":"352_CR17","doi-asserted-by":"publisher","first-page":"1796","DOI":"10.1002\/mds.26058","volume":"29","author":"K Dujardin","year":"2014","unstructured":"Dujardin K, Langlois C, Plomhause L et al (2014) Apathy in untreated early-stage Parkinson disease: relationship with other non-motor symptoms. Mov Disord 29:1796\u20131801","journal-title":"Mov Disord"},{"key":"352_CR18","doi-asserted-by":"publisher","first-page":"425","DOI":"10.3233\/NRE-2007-22604","volume":"22","author":"LB Elman","year":"2007","unstructured":"Elman LB, Grossman M (2007) Neuropsychiatric features of amyotrophic lateral sclerosis. NeuroRehabilitation 22:425\u2013429","journal-title":"NeuroRehabilitation"},{"key":"352_CR19","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1016\/S1474-4422(19)30411-9","volume":"19","author":"VL Feigin","year":"2020","unstructured":"Feigin VL, Vos T, Nichols E et al (2020) The global burden of neurological disorders: translating evidence into policy. Lancet Neurol 19:255\u2013265","journal-title":"Lancet Neurol"},{"key":"352_CR20","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1111\/j.1447-0594.2010.00678.x","volume":"11","author":"S Fujiwara","year":"2011","unstructured":"Fujiwara S, Kimura F, Hosokawa T et al (2011) Anhedonia in Japanese patients with Parkinson\u2019s disease. Geriatr Gerontol Int 11:275\u2013281","journal-title":"Geriatr Gerontol Int"},{"key":"352_CR21","doi-asserted-by":"publisher","first-page":"1135","DOI":"10.1016\/j.neuropsychologia.2006.10.015","volume":"45","author":"CJ Hayes","year":"2007","unstructured":"Hayes CJ, Stevenson RJ, Coltheart M (2007) Disgust and Huntington\u2019s disease. Neuropsychologia 45:1135\u20131151","journal-title":"Neuropsychologia"},{"key":"352_CR22","doi-asserted-by":"publisher","first-page":"1467","DOI":"10.3233\/JAD-171087","volume":"62","author":"JR Hodges","year":"2018","unstructured":"Hodges JR, Piguet O (2018) Progress and challenges in frontotemporal dementia research: a 20-year review. J Alzheimers Dis 62:1467\u20131480","journal-title":"J Alzheimers Dis"},{"key":"352_CR23","doi-asserted-by":"publisher","first-page":"470","DOI":"10.1038\/s41583-018-0029-9","volume":"19","author":"M Husain","year":"2018","unstructured":"Husain M, Roiser JP (2018) Neuroscience of apathy and anhedonia: a transdiagnostic approach. Nat Rev Neurosci 19:470\u2013484","journal-title":"Nat Rev Neurosci"},{"key":"352_CR24","doi-asserted-by":"publisher","first-page":"1308","DOI":"10.1136\/jnnp.74.9.1308","volume":"74","author":"V Isella","year":"2003","unstructured":"Isella V, Iurlaro S, Piolti R et al (2003) Physical anhedonia in Parkinson\u2019s disease. J Neurol Neurosurg Psychiatry 74:1308\u20131311","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"352_CR25","doi-asserted-by":"publisher","first-page":"1301","DOI":"10.1002\/mds.25496","volume":"28","author":"LL Jordan","year":"2013","unstructured":"Jordan LL, Zahodne LB, Okun MS, Bowers D (2013) Hedonic and behavioral deficits associated with apathy in Parkinson\u2019s disease: potential treatment implications. Mov Disord 28:1301\u20131304","journal-title":"Mov Disord"},{"key":"352_CR26","doi-asserted-by":"publisher","first-page":"219427","DOI":"10.5402\/2011\/219427","volume":"2011","author":"Y Kaji","year":"2011","unstructured":"Kaji Y, Hirata K (2011) Apathy and anhedonia in Parkinson\u2019s disease. ISRN Neurol 2011:219427","journal-title":"ISRN Neurol"},{"key":"352_CR27","first-page":"1","volume-title":"Anhedonia and affect deficit states","author":"D Klein","year":"1984","unstructured":"Klein D (1984) Depression and anhedonia. In: Clark DC, Fawcett J (eds) Anhedonia and affect deficit states. PMA Publishing, New York, pp 1\u201314"},{"key":"352_CR28","doi-asserted-by":"publisher","first-page":"1792","DOI":"10.1093\/brain\/awx101","volume":"140","author":"CJ Lansdall","year":"2017","unstructured":"Lansdall CJ, Coyle-Gilchrist ITS, Jones PS et al (2017) Apathy and impulsivity in frontotemporal lobar degeneration syndromes. Brain 140:1792\u20131807","journal-title":"Brain"},{"key":"352_CR29","doi-asserted-by":"publisher","first-page":"1040","DOI":"10.1002\/gps.2030","volume":"23","author":"H Lavretsky","year":"2008","unstructured":"Lavretsky H, Zheng L, Weiner MW et al (2008) The MRI brain correlates of depressed mood, anhedonia, apathy, and anergia in older adults with and without cognitive impairment or dementia. Int J Geriatr Psychiatry 23:1040\u20131050","journal-title":"Int J Geriatr Psychiatry"},{"key":"352_CR30","doi-asserted-by":"publisher","first-page":"575","DOI":"10.30773\/pi.2019.06.07","volume":"16","author":"JR Lee","year":"2019","unstructured":"Lee JR, Suh SW, Han JW et al (2019) Anhedonia and dysphoria are differentially associated with the risk of dementia in the cognitively normal elderly individuals: a prospective cohort study. Psychiatry Investig 16:575\u2013580","journal-title":"Psychiatry Investig"},{"key":"352_CR31","doi-asserted-by":"publisher","first-page":"214","DOI":"10.1176\/jnp.17.2.214","volume":"17","author":"MR Lemke","year":"2005","unstructured":"Lemke MR (2005) Anhedonia, depression, and motor functioning in Parkinson\u2019s disease during treatment with pramipexole. J Neuropsychiatry Clin Neurosci 17:214\u2013220","journal-title":"J Neuropsychiatry Clin Neurosci"},{"key":"352_CR32","doi-asserted-by":"publisher","first-page":"214","DOI":"10.1176\/jnp.17.2.214","volume":"17","author":"MR Lemke","year":"2005","unstructured":"Lemke MR, Brecht HM, Koester J et al (2005) Anhedonia, depression, and motor functioning in Parkinson\u2019s disease during treatment with pramipexole. J Neuropsychiatry Clin Neurosci 17:214\u2013220","journal-title":"J Neuropsychiatry Clin Neurosci"},{"key":"352_CR33","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1016\/j.jns.2006.05.024","volume":"248","author":"MR Lemke","year":"2006","unstructured":"Lemke MR, Brecht HM, Koester J, Reichmann H (2006) Effects of the dopamine agonist pramipexole on depression, anhedonia and motor functioning in Parkinson\u2019s disease. J Neurol Sci 248:266\u2013270","journal-title":"J Neurol Sci"},{"key":"352_CR34","doi-asserted-by":"publisher","first-page":"916","DOI":"10.1093\/cercor\/bhj043","volume":"16","author":"R Levy","year":"2006","unstructured":"Levy R, Dubois B (2006) Apathy and the functional anatomy of the prefrontal cortex-basal ganglia circuits. Cereb Cortex 16:916\u2013928","journal-title":"Cereb Cortex"},{"key":"352_CR35","doi-asserted-by":"publisher","first-page":"24","DOI":"10.3389\/fneur.2014.00024","volume":"5","author":"G Loas","year":"2014","unstructured":"Loas G, Duru C, Godefroy O, Krystkowiak P (2014) Hedonic deficits in Parkinson\u2019s disease: is consummatory anhedonia specific? Front Neurol 5:24","journal-title":"Front Neurol"},{"key":"352_CR36","doi-asserted-by":"publisher","first-page":"346","DOI":"10.1176\/jnp.15.3.346","volume":"15","author":"OL Lopez","year":"2003","unstructured":"Lopez OL, Becker JT, Sweet RA et al (2003) Psychiatric symptoms vary with the severity of dementia in probable Alzheimer\u2019s disease. J Neuropsychiatry Clin Neurosci 15:346\u2013353","journal-title":"J Neuropsychiatry Clin Neurosci"},{"key":"352_CR37","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1080\/13554790490896893","volume":"11","author":"OL Lopez","year":"2005","unstructured":"Lopez OL, Becker JT, Sweet RA (2005) Non-cognitive symptoms in mild cognitive impairment subjects. Neurocase 11:65\u201371","journal-title":"Neurocase"},{"key":"352_CR38","doi-asserted-by":"publisher","first-page":"971","DOI":"10.1016\/0092-8674(93)90585-E","volume":"72","author":"M MacDonald","year":"1993","unstructured":"MacDonald M (1993) A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington\u2019s disease chromosomes. Cell 72:971\u2013983","journal-title":"Cell"},{"key":"352_CR39","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1176\/jnp.3.3.243","volume":"3","author":"RS Marin","year":"1991","unstructured":"Marin RS (1991) Apathy: a neuropsychiatric syndrome. J Neuropsychiatry Clin Neurosci 3:243\u2013254","journal-title":"J Neuropsychiatry Clin Neurosci"},{"key":"352_CR40","doi-asserted-by":"publisher","first-page":"474","DOI":"10.1016\/j.nrl.2016.05.002","volume":"33","author":"HR Mart\u00ednez","year":"2018","unstructured":"Mart\u00ednez HR, Escamilla-Oca\u00f1as CE, Hern\u00e1ndez-Torre M (2018) Non-motor neurological symptoms in patients with amyotrophic lateral sclerosis. Neurologia 33:474\u2013476","journal-title":"Neurologia"},{"key":"352_CR41","doi-asserted-by":"publisher","first-page":"A55","DOI":"10.1136\/jnnp-2016-314597.154","volume":"87","author":"F Marxreiter","year":"2016","unstructured":"Marxreiter F, Mrochen A, Kozay C et al (2016) G3 hedonic olfaction in huntington\u2019s disease. J Neurol Neurosurg Psychiatry 87:A55\u2013A55","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"352_CR42","doi-asserted-by":"publisher","first-page":"611","DOI":"10.3389\/fnhum.2015.00611","volume":"9","author":"L Massimo","year":"2015","unstructured":"Massimo L, Powers JP, Evans LK et al (2015) Apathy in frontotemporal degeneration: neuroanatomical evidence of impaired goal-directed behavior. Front Hum Neurosci 9:611","journal-title":"Front Hum Neurosci"},{"key":"352_CR43","doi-asserted-by":"publisher","first-page":"2524","DOI":"10.1016\/j.clineuro.2013.10.013","volume":"115","author":"K Matsui","year":"2013","unstructured":"Matsui K, Tachibana H, Yamanishi T et al (2013) Clinical correlates of anhedonia in patients with Parkinson\u2019s disease. Clin Neurol Neurosurg 115:2524\u20132527","journal-title":"Clin Neurol Neurosurg"},{"key":"352_CR44","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1212\/WNL.0000000000004058","volume":"89","author":"IG McKeith","year":"2017","unstructured":"McKeith IG, Boeve BF, Dickson DW et al (2017) Diagnosis and management of dementia with Lewy bodies. Neurology 89:88\u2013100","journal-title":"Neurology"},{"key":"352_CR45","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1097\/01.wnn.0000191292.17964.bb","volume":"18","author":"MF Mendez","year":"2005","unstructured":"Mendez MF, Anderson E, Shapira JS (2005) An investigation of moral judgement in frontotemporal dementia. Cogn Behav Neurol 18:193\u2013197","journal-title":"Cogn Behav Neurol"},{"key":"352_CR46","doi-asserted-by":"publisher","first-page":"352","DOI":"10.1016\/j.clineuro.2011.11.008","volume":"114","author":"S Miura","year":"2012","unstructured":"Miura S, Kida H, Nakajima J et al (2012) Anhedonia in Japanese patients with Parkinson\u2019s disease: analysis using the Snaith-Hamilton pleasure scale. Clin Neurol Neurosurg 114:352\u2013355","journal-title":"Clin Neurol Neurosurg"},{"key":"352_CR47","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1016\/j.parkreldis.2015.09.035","volume":"22","author":"A Mrochen","year":"2016","unstructured":"Mrochen A, Marxreiter F, Kohl Z et al (2016) From sweet to sweat: hedonic olfactory range is impaired in Parkinson\u2019s disease. Park Relat Disord 22:9\u201314","journal-title":"Park Relat Disord"},{"key":"352_CR48","doi-asserted-by":"publisher","first-page":"865","DOI":"10.2169\/internalmedicine.51.6718","volume":"51","author":"H Nagayama","year":"2012","unstructured":"Nagayama H, Kubo S, Hatano T et al (2012) Validity and reliability assessment of a Japanese version of the Snaith-Hamilton pleasure scale. Intern Med 51:865\u2013869","journal-title":"Intern Med"},{"key":"352_CR49","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1016\/j.jns.2016.10.051","volume":"372","author":"H Nagayama","year":"2017","unstructured":"Nagayama H, Maeda T, Uchiyama T et al (2017) Anhedonia and its correlation with clinical aspects in Parkinson\u2019s disease. J Neurol Sci 372:403\u2013407","journal-title":"J Neurol Sci"},{"key":"352_CR50","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1016\/j.jns.2018.11.005","volume":"396","author":"H Nagayama","year":"2019","unstructured":"Nagayama H, Kano O, Murakami H et al (2019) Effect of istradefylline on mood disorders in Parkinson\u2019s disease. J Neurol Sci 396:78\u201383","journal-title":"J Neurol Sci"},{"key":"352_CR51","doi-asserted-by":"publisher","first-page":"S78","DOI":"10.1016\/j.jagp.2012.12.102","volume":"21","author":"LE Natta","year":"2013","unstructured":"Natta LE, Melrose RJ, Harwood DG, Sultzer DL (2013) An examination of anhedonia separate from depression in Alzheimer\u2019s disease: a preliminary study. Am J Geriatr Psychiatry 21:S78\u2013S79","journal-title":"Am J Geriatr Psychiatry"},{"key":"352_CR52","doi-asserted-by":"publisher","first-page":"636","DOI":"10.1136\/jnnp.73.6.636","volume":"73","author":"GC Pluck","year":"2002","unstructured":"Pluck GC, Brown RG (2002) Apathy in Parkinson\u2019s disease. J Neurol Neurosurg Psychiatry 73:636\u2013642","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"352_CR53","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1016\/j.baga.2014.03.004","volume":"4","author":"M Pomponi","year":"2014","unstructured":"Pomponi M, Loria G, Salvati S et al (2014) DHA effects in Parkinson disease depression. Basal Ganglia 4:61\u201366","journal-title":"Basal Ganglia"},{"key":"352_CR54","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1212\/01.wnl.0000167187.14501.0c","volume":"65","author":"JG Rabkin","year":"2005","unstructured":"Rabkin JG, Albert SM, Del BML et al (2005) Prevalence of depressive disorders and change over time in late-stage ALS. Neurology 65:62\u201367","journal-title":"Neurology"},{"key":"352_CR55","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1177\/089198879500800203","volume":"8","author":"WE Reichman","year":"1995","unstructured":"Reichman WE, Coyne AC (1995) Depressive symptoms in Alzheimer\u2019s disease and multi-infarct dementia. J Geriatr Psychiatry Neurol 8:96\u201399","journal-title":"J Geriatr Psychiatry Neurol"},{"key":"352_CR56","volume-title":"La Psychologie des sentiment [The psychology of feelings]","author":"T Ribot","year":"1896","unstructured":"Ribot T (1896) La Psychologie des sentiment [The psychology of feelings]. Felix Alcan, Paris"},{"key":"352_CR57","doi-asserted-by":"publisher","first-page":"819","DOI":"10.1002\/1099-1166(200009)15:9<819::AID-GPS206>3.0.CO;2-1","volume":"15","author":"E Rockwell","year":"2000","unstructured":"Rockwell E, Choure J, Galasko D et al (2000) Psychopathology at initial diagnosis in dementia with Lewy bodies versus Alzheimer disease: comparison of matched groups with autopsy-confirmed diagnoses. Int J Geriatr Psychiatry 15:819\u2013823","journal-title":"Int J Geriatr Psychiatry"},{"key":"352_CR58","doi-asserted-by":"publisher","first-page":"576","DOI":"10.1016\/j.parkreldis.2009.02.004","volume":"15","author":"G Santangelo","year":"2009","unstructured":"Santangelo G, Morgante L, Savica R et al (2009a) Anhedonia and cognitive impairment in Parkinson\u2019s disease: Italian validation of the Snaith-Hamilton pleasure scale and its application in the clinical routine practice during the PRIAMO study. Park Relat Disord 15:576\u2013581","journal-title":"Park Relat Disord"},{"key":"352_CR59","doi-asserted-by":"publisher","first-page":"632","DOI":"10.1007\/s00415-009-0146-5","volume":"256","author":"G Santangelo","year":"2009","unstructured":"Santangelo G, Vitale C, Trojano L et al (2009b) Relationship between depression and cognitive dysfunctions in Parkinson\u2019s disease without dementia. J Neurol 256:632\u2013638","journal-title":"J Neurol"},{"key":"352_CR60","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1111\/j.1600-0447.2008.01280.x","volume":"119","author":"P Saz","year":"2009","unstructured":"Saz P, L\u00f3pez-Ant\u00f3n R, Dewey ME et al (2009) Prevalence and implications of psychopathological non-cognitive symptoms in dementia. Acta Psychiatr Scand 119:107\u2013116","journal-title":"Acta Psychiatr Scand"},{"key":"352_CR61","doi-asserted-by":"publisher","first-page":"998","DOI":"10.3390\/brainsci11080998","volume":"11","author":"SR Shaw","year":"2021","unstructured":"Shaw SR, El-Omar H, Ramanan S et al (2021a) Anhedonia in semantic dementia\u2014exploring right hemispheric contributions to the loss of pleasure. Brain Sci 11:998","journal-title":"Brain Sci"},{"key":"352_CR62","doi-asserted-by":"publisher","first-page":"1551","DOI":"10.1093\/brain\/awab032","volume":"144","author":"SR Shaw","year":"2021","unstructured":"Shaw SR, El-Omar H, Roquet D et al (2021b) Uncovering the prevalence and neural substrates of anhedonia in frontotemporal dementia. Brain 144:1551\u20131564","journal-title":"Brain"},{"key":"352_CR63","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1192\/bjp.167.1.99","volume":"167","author":"RP Snaith","year":"1995","unstructured":"Snaith RP, Hamilton M, Morley S et al (1995) A scale for the assessment of hedonic tone the Snaith\u2013Hamilton pleasure scale. Br J Psychiatry 167:99\u2013103","journal-title":"Br J Psychiatry"},{"key":"352_CR64","doi-asserted-by":"publisher","first-page":"382","DOI":"10.1007\/s00415-013-7207-5","volume":"261","author":"P Solla","year":"2014","unstructured":"Solla P, Cannas A, Mulas CS et al (2014) Association between fatigue and other motor and non-motor symptoms in Parkinson\u2019s disease patients. J Neurol 261:382\u2013391","journal-title":"J Neurol"},{"key":"352_CR65","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1002\/da.22036","volume":"30","author":"G Spalletta","year":"2013","unstructured":"Spalletta G, Fagioli S, Meco G et al (2013) Hedonic tone and its mood and cognitive correlates in Parkinson\u2019s disease. Depress Anxiety 30:85\u201391","journal-title":"Depress Anxiety"},{"key":"352_CR66","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1007\/s11940-011-0118-9","volume":"13","author":"SE Starkstein","year":"2011","unstructured":"Starkstein SE, Brockman S (2011) Apathy and Parkinson\u2019s disease. Curr Treat Options Neurol 13:267\u2013273","journal-title":"Curr Treat Options Neurol"},{"key":"352_CR67","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1038\/s41582-018-0014-y","volume":"14","author":"A ter Telgte","year":"2018","unstructured":"ter Telgte A, van Leijsen EMC, Wiegertjes K et al (2018) Cerebral small vessel disease: from a focal to a global perspective. Nat Rev Neurol 14:387\u2013398","journal-title":"Nat Rev Neurol"},{"key":"352_CR68","doi-asserted-by":"publisher","first-page":"1568","DOI":"10.1093\/brain\/awt067","volume":"136","author":"S Thobois","year":"2013","unstructured":"Thobois S, Lhomm\u00e9e E, Klinger H et al (2013) Parkinsonian apathy responds to dopaminergic stimulation of D2\/D3 receptors with piribedil. Brain 136:1568\u20131577","journal-title":"Brain"},{"key":"352_CR69","doi-asserted-by":"publisher","first-page":"537","DOI":"10.1016\/j.neubiorev.2010.06.006","volume":"35","author":"MT Treadway","year":"2011","unstructured":"Treadway MT, Zald DH (2011) Reconsidering anhedonia in depression: lessons from translational neuroscience. Neurosci Biobehav Rev 35:537\u2013555","journal-title":"Neurosci Biobehav Rev"},{"key":"352_CR70","doi-asserted-by":"publisher","first-page":"e2013233","DOI":"10.1001\/jamanetworkopen.2020.13233","volume":"3","author":"M Tr\u00f8stheim","year":"2020","unstructured":"Tr\u00f8stheim M, Eikemo M, Meir R et al (2020) Assessment of anhedonia in adults with and without mental illness: a systematic review and meta-analysis. JAMA Netw Open 3:e2013233","journal-title":"JAMA Netw Open"},{"key":"352_CR71","first-page":"1","volume":"4","author":"WM van der Flier","year":"2018","unstructured":"van der Flier WM, Skoog I, Schneider JA et al (2018) Vascular cognitive impairment. Nat Rev Dis Prim 4:1\u201316","journal-title":"Nat Rev Dis Prim"},{"key":"352_CR72","doi-asserted-by":"publisher","first-page":"1411","DOI":"10.1136\/jnnp-2013-307343","volume":"85","author":"E van Duijn","year":"2014","unstructured":"van Duijn E, Craufurd D, Hubers AAM et al (2014) Neuropsychiatric symptoms in a European Huntington\u2019s disease cohort (REGISTRY). J Neurol Neurosurg Psychiatry 85:1411\u20131418","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"352_CR73","doi-asserted-by":"publisher","first-page":"218","DOI":"10.1016\/S0140-6736(07)60111-1","volume":"369","author":"FO Walker","year":"2007","unstructured":"Walker FO (2007) Huntington\u2019s disease. Lancet 369:218\u2013228","journal-title":"Lancet"},{"key":"352_CR74","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1097\/YCO.0000000000000122","volume":"28","author":"AE Whitton","year":"2015","unstructured":"Whitton AE, Treadway MT, Pizzagalli DA (2015) Reward processing dysfunction in major depression, bipolar disorder and schizophrenia. Curr Opin Psychiatry 28:7\u201312","journal-title":"Curr Opin Psychiatry"},{"key":"352_CR75","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1176\/jnp.2006.18.3.397","volume":"18","author":"K Witt","year":"2006","unstructured":"Witt K, Daniels C, Herzog J et al (2006) Differential effects of l-dopa and subthalamic stimulation on depressive symptoms and hedonic tone in Parkinson\u2019s disease. J Neuropsychiatry Clin Neurosci 18:397\u2013401","journal-title":"J Neuropsychiatry Clin Neurosci"},{"key":"352_CR76","doi-asserted-by":"publisher","first-page":"264","DOI":"10.1016\/j.jad.2015.09.069","volume":"190","author":"QF Zhao","year":"2016","unstructured":"Zhao QF, Tan L, Wang HF et al (2016) The prevalence of neuropsychiatric symptoms in Alzheimer\u2019s disease: systematic review and meta-analysis. J Affect Disord 190:264\u2013271","journal-title":"J Affect Disord"}],"container-title":["Current Topics in Behavioral Neurosciences","Anhedonia: Preclinical, Translational, and Clinical Integration"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/7854_2022_352","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,8]],"date-time":"2022-08-08T20:03:48Z","timestamp":1659989028000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/7854_2022_352"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022]]},"ISBN":["9783031096822","9783031096839"],"references-count":76,"URL":"https:\/\/doi.org\/10.1007\/7854_2022_352","relation":{},"ISSN":["1866-3370","1866-3389"],"issn-type":[{"value":"1866-3370","type":"print"},{"value":"1866-3389","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022]]},"assertion":[{"value":"19 April 2022","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}}]}}