{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T10:35:52Z","timestamp":1756463752643,"version":"3.40.3"},"publisher-location":"Cham","reference-count":74,"publisher":"Springer International Publishing","isbn-type":[{"type":"print","value":"9783031153044"},{"type":"electronic","value":"9783031153051"}],"license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022]]},"DOI":"10.1007\/82_2022_255","type":"book-chapter","created":{"date-parts":[[2022,3,15]],"date-time":"2022-03-15T17:03:05Z","timestamp":1647363785000},"page":"135-161","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Humanized Severe Combined Immunodeficient (SCID) Mouse Models for Varicella-Zoster Virus Pathogenesis"],"prefix":"10.1007","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6034-0846","authenticated-orcid":false,"given":"Megan G.","family":"Lloyd","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4371-8608","authenticated-orcid":false,"given":"Jennifer F.","family":"Moffat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,3,16]]},"reference":[{"key":"255_CR1","doi-asserted-by":"crossref","unstructured":"Abeynaike S, Paust S (2021) Humanized mice for the evaluation of novel HIV-1 therapies. Front Immunol 12:636775","DOI":"10.3389\/fimmu.2021.636775"},{"key":"255_CR2","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1016\/j.virol.2012.10.007","volume":"435","author":"R Akkina","year":"2013","unstructured":"Akkina R (2013) New generation humanized mice for virus research: comparative aspects and future prospects. Virology 435:14\u201328","journal-title":"Virology"},{"key":"255_CR3","unstructured":"Anonymous (2021) Important factors for experimental success in xenograft host selection. Taconic Biosciences, Inc."},{"key":"255_CR4","doi-asserted-by":"publisher","first-page":"34164","DOI":"10.1038\/srep34164","volume":"6","author":"N Arnold","year":"2016","unstructured":"Arnold N, Girke T, Sureshchandra S, Nguyen C, Rais M, Messaoudi I (2016) Genomic and functional analysis of the host response to acute simian varicella infection in the lung. Sci Rep 6:34164","journal-title":"Sci Rep"},{"key":"255_CR5","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1007\/978-1-4939-1133-2_18","volume":"1185","author":"KE Aryee","year":"2014","unstructured":"Aryee KE, Shultz LD, Brehm MA (2014) Immunodeficient mouse model for human hematopoietic stem cell engraftment and immune system development. Methods Mol Biol 1185:267\u2013278","journal-title":"Methods Mol Biol"},{"key":"255_CR6","doi-asserted-by":"publisher","first-page":"282","DOI":"10.1073\/pnas.0912373107","volume":"107","author":"B Berarducci","year":"2010","unstructured":"Berarducci B, Rajamani J, Zerboni L, Che X, Sommer M, Arvin AM (2010) Functions of the unique N-terminal region of glycoprotein E in the pathogenesis of varicella-zoster virus infection. Proc Natl Acad Sci U S A 107:282\u2013287","journal-title":"Proc Natl Acad Sci U S A"},{"key":"255_CR7","doi-asserted-by":"publisher","first-page":"5964","DOI":"10.1128\/JVI.77.10.5964-5974.2003","volume":"77","author":"J Besser","year":"2003","unstructured":"Besser J, Sommer MH, Zerboni L, Bagowski CP, Ito H, Moffat J, Ku CC, Arvin AM (2003) Differentiation of varicella-zoster virus ORF47 protein kinase and IE62 protein binding domains and their contributions to replication in human skin xenografts in the SCID-hu mouse. J Virol 77:5964\u20135974","journal-title":"J Virol"},{"key":"255_CR8","doi-asserted-by":"publisher","first-page":"728","DOI":"10.1038\/363728a0","volume":"363","author":"ML Bonyhadi","year":"1993","unstructured":"Bonyhadi ML, Rabin L, Salimi S, Brown DA, Kosek J, McCune JM, Kaneshima H (1993) HIV induces thymus depletion in vivo. Nature 363:728\u2013732","journal-title":"Nature"},{"key":"255_CR9","doi-asserted-by":"publisher","first-page":"2935","DOI":"10.3389\/fmicb.2018.02935","volume":"9","author":"EM Buckingham","year":"2018","unstructured":"Buckingham EM, Girsch J, Jackson W, Cohen JI, Grose C (2018) Autophagy quantification and STAT3 expression in a human skin organ culture model for innate immunity to herpes zoster. Front Microbiol 9:2935","journal-title":"Front Microbiol"},{"key":"255_CR10","doi-asserted-by":"publisher","first-page":"5825","DOI":"10.1128\/JVI.00303-08","volume":"82","author":"X Che","year":"2008","unstructured":"Che X, Reichelt M, Sommer MH, Rajamani J, Zerboni L, Arvin AM (2008) Functions of the ORF9-to-ORF12 gene cluster in varicella-zoster virus replication and in the pathogenesis of skin infection. J Virol 82:5825\u20135834","journal-title":"J Virol"},{"key":"255_CR11","doi-asserted-by":"publisher","first-page":"215","DOI":"10.3109\/00365540903428166","volume":"42","author":"E Chiner","year":"2010","unstructured":"Chiner E, Ballester I, Betlloch I, Blanquer J, Aguar MC, Blanquer R, Fernandez-Fabrellas E, Andreu AL, Briones M, Sanz F (2010) Varicella-zoster virus pneumonia in an adult population: has mortality decreased? Scand J Infect Dis 42:215\u2013221","journal-title":"Scand J Infect Dis"},{"key":"255_CR12","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1007\/s00403-009-0989-8","volume":"302","author":"NA Coolen","year":"2010","unstructured":"Coolen NA, Schouten KC, Middelkoop E, Ulrich MM (2010) Comparison between human fetal and adult skin. Arch Dermatol Res 302:47\u201355","journal-title":"Arch Dermatol Res"},{"key":"255_CR13","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1016\/j.antiviral.2014.07.007","volume":"110","author":"C De","year":"2014","unstructured":"De C, Liu D, Zheng B, Singh US, Chavre S, White C, Arnold RD, Hagen FK, Chu CK, Moffat JF (2014) Beta-l-1-[5-(E-2-bromovinyl)-2-(hydroxymethyl)-1,3-(dioxolan-4-yl)] uracil (l-BHDU) prevents varicella-zoster virus replication in a SCID-Hu mouse model and does not interfere with 5-fluorouracil catabolism. Antiviral Res 110:10\u201319","journal-title":"Antiviral Res"},{"key":"255_CR14","doi-asserted-by":"publisher","first-page":"1857","DOI":"10.1084\/jem.190.12.1857","volume":"190","author":"D Dittmer","year":"1999","unstructured":"Dittmer D, Stoddart C, Renne R, Linquist-Stepps V, Moreno ME, Bare C, McCune JM, Ganem D (1999) Experimental transmission of Kaposi\u2019s sarcoma-associated herpesvirus (KSHV\/HHV-8) to SCID-hu Thy\/Liv mice. J Exp Med 190:1857\u20131868","journal-title":"J Exp Med"},{"key":"255_CR15","doi-asserted-by":"publisher","first-page":"1953","DOI":"10.1084\/jem.189.12.1953","volume":"189","author":"A Gobbi","year":"1999","unstructured":"Gobbi A, Stoddart CA, Malnati MS, Locatelli G, Santoro F, Abbey NW, Bare C, Linquist-Stepps V, Moreno MB, Herndier BG, Lusso P, McCune JM (1999) Human herpesvirus 6 (HHV-6) causes severe thymocyte depletion in SCID-hu Thy\/Liv mice. J Exp Med 189:1953\u20131960","journal-title":"J Exp Med"},{"key":"255_CR16","doi-asserted-by":"publisher","first-page":"8726","DOI":"10.1128\/JVI.74.18.8726-8731.2000","volume":"74","author":"A Gobbi","year":"2000","unstructured":"Gobbi A, Stoddart CA, Locatelli G, Santoro F, Bare C, Linquist-Stepps V, Moreno ME, Abbey NW, Herndier BG, Malnati MS, McCune JM, Lusso P (2000) Coinfection of SCID-hu Thy\/Liv mice with human herpesvirus 6 and human immunodeficiency virus type 1. J Virol 74:8726\u20138731","journal-title":"J Virol"},{"key":"255_CR17","doi-asserted-by":"publisher","first-page":"12777","DOI":"10.1128\/JVI.01814-14","volume":"88","author":"K Haberthur","year":"2014","unstructured":"Haberthur K, Meyer C, Arnold N, Engelmann F, Jeske DR, Messaoudi I (2014) Intrabronchial infection of rhesus macaques with simian varicella virus results in a robust immune response in the lungs. J Virol 88:12777\u201312792","journal-title":"J Virol"},{"key":"255_CR18","first-page":"3175","volume":"100","author":"M Ito","year":"2002","unstructured":"Ito M, Hiramatsu H, Kobayashi K, Suzue K, Kawahata M, Hioki K, Ueyama Y, Koyanagi Y, Sugamura K, Tsuji K (2002) NOD\/SCID\/\u03b3 c null mouse: an excellent recipient mouse model for engraftment of human cells. Blood, J Am Soc Hematol 100:3175\u20133182","journal-title":"Blood, J Am Soc Hematol"},{"key":"255_CR19","doi-asserted-by":"crossref","unstructured":"Jarosinski KW, Carpenter JE, Buckingham EM, Jackson W, Knudtson K, Moffat JF, Kita H, Grose C (2018) Cellular stress response to varicella-zoster virus infection of human skin includes highly elevated interleukin-6 expression. Open Forum Infect Dis 5:ofy118","DOI":"10.1093\/ofid\/ofy118"},{"key":"255_CR20","doi-asserted-by":"publisher","first-page":"1862","DOI":"10.3389\/fmicb.2020.01862","volume":"11","author":"T Keil","year":"2020","unstructured":"Keil T, Liu D, Lloyd M, Coombs W, Moffat J, Visalli R (2020) DNA encapsidation and capsid assembly are underexploited antiviral targets for the treatment of herpesviruses. Front Microbiol 11:1862","journal-title":"Front Microbiol"},{"key":"255_CR21","doi-asserted-by":"publisher","first-page":"827","DOI":"10.1016\/j.ejca.2003.11.028","volume":"40","author":"L Kelland","year":"2004","unstructured":"Kelland L (2004) \u201cOf mice and men\u201d: values and liabilities of the athymic nude mouse model in anticancer drug development. Eur J Cancer 40:827\u2013836","journal-title":"Eur J Cancer"},{"key":"255_CR22","doi-asserted-by":"publisher","first-page":"2392","DOI":"10.1128\/jvi.63.5.2392-2395.1989","volume":"63","author":"CM Koropchak","year":"1989","unstructured":"Koropchak CM, Solem SM, Diaz PS, Arvin AM (1989) Investigation of varicella-zoster virus infection of lymphocytes by in situ hybridization. J Virol 63:2392\u20132395","journal-title":"J Virol"},{"key":"255_CR23","doi-asserted-by":"publisher","first-page":"917","DOI":"10.1084\/jem.20040634","volume":"200","author":"CC Ku","year":"2004","unstructured":"Ku CC, Zerboni L, Ito H, Graham BS, Wallace M, Arvin AM (2004) Varicella-zoster virus transfer to skin by T Cells and modulation of viral replication by epidermal cell interferon-alpha. J Exp Med 200:917\u2013925","journal-title":"J Exp Med"},{"key":"255_CR24","doi-asserted-by":"publisher","first-page":"2651","DOI":"10.1128\/JVI.79.5.2651-2658.2005","volume":"79","author":"CC Ku","year":"2005","unstructured":"Ku CC, Besser J, Abendroth A, Grose C, Arvin AM (2005) Varicella-Zoster virus pathogenesis and immunobiology: new concepts emerging from investigations with the SCIDhu mouse model. J Virol 79:2651\u20132658","journal-title":"J Virol"},{"key":"255_CR25","unstructured":"Liu X (2020) Top tips on selecting the \u201cBest\u201d immunodeficient mouse model for your research. https:\/\/www.jax.org\/news-and-insights\/jax-blog\/2020\/may\/top-tips-selecting-the-best-immunodeficient-mouse-model-for-your-research"},{"key":"255_CR28","doi-asserted-by":"crossref","unstructured":"Lloyd MG, Liu D, Lyu J, Fan J, Overhulse J, Kashemirov BA, Prichard MN, McKenna CE, Moffat JF (2022a) An acyclic phosphonate prodrug of HPMPC is effective against VZV in skin organ culture and mice. Antiviral Res 199:105275","DOI":"10.1016\/j.antiviral.2022.105275"},{"key":"255_CR26","doi-asserted-by":"publisher","first-page":"1641","DOI":"10.1038\/s41598-022-05580-6","volume":"12","author":"MG Lloyd","year":"2022","unstructured":"Lloyd MG, Liu D, Legendre M, Markovitz DM, Moffat JF (2022b) H84T BanLec has broad spectrum antiviral activity against human herpesviruses in cells, skin, and mice. Sci Rep 12:1641","journal-title":"Sci Rep"},{"key":"255_CR27","doi-asserted-by":"crossref","unstructured":"Lloyd MG, Smith NA, Tighe M, Travis KL, Liu D, Upadhyaya PK, Kinchington PR, Chan GC, Moffat JF (2020) A novel human skin tissue model to study varicella-zoster virus and human cytomegalovirus. J Virol 94","DOI":"10.1128\/JVI.01082-20"},{"key":"255_CR29","first-page":"731","volume":"54","author":"CR Lockworth","year":"2015","unstructured":"Lockworth CR, Kim S-J, Liu J, Palla SL, Craig SL (2015) Effect of enrichment devices on aggression in manipulated nude mice. J Am Assoc Lab Anim Sci 54:731\u2013736","journal-title":"J Am Assoc Lab Anim Sci"},{"key":"255_CR30","doi-asserted-by":"publisher","unstructured":"Marx A (2020) The normal thymus, pp 1\u201310. In: Jain D, Bishop JA, Wick MR (eds), Atlas of thymic pathology. https:\/\/doi.org\/10.1007\/978-981-15-3164-4_1. Springer Singapore, Singapore","DOI":"10.1007\/978-981-15-3164-4_1"},{"key":"255_CR31","doi-asserted-by":"publisher","first-page":"1632","DOI":"10.1126\/science.2971269","volume":"241","author":"JM McCune","year":"1988","unstructured":"McCune JM, Namikawa R, Kaneshima H, Shultz LD, Lieberman M, Weissman IL (1988) The SCID-hu mouse: murine model for the analysis of human hematolymphoid differentiation and function. Science 241:1632\u20131639","journal-title":"Science"},{"key":"255_CR32","doi-asserted-by":"publisher","first-page":"564","DOI":"10.1126\/science.2300816","volume":"247","author":"JM McCune","year":"1990","unstructured":"McCune JM, Namikawa R, Shih CC, Rabin L, Kaneshima H (1990) Suppression of HIV infection in AZT-treated SCID-hu mice. Science 247:564\u2013566","journal-title":"Science"},{"key":"255_CR33","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1146\/annurev.iy.09.040191.002151","volume":"9","author":"J McCune","year":"1991","unstructured":"McCune J, Kaneshima H, Krowka J, Namikawa R, Outzen H, Peault B, Rabin L, Shih CC, Yee E, Lieberman M et al (1991) The SCID-hu mouse: a small animal model for HIV infection and pathogenesis. Annu Rev Immunol 9:399\u2013429","journal-title":"Annu Rev Immunol"},{"key":"255_CR34","doi-asserted-by":"crossref","unstructured":"Messaoudi I, Barron A, Wellish M, Engelmann F, Legasse A, Planer S, Gilden D, Nikolich-Zugich J, Mahalingam R (2009) Simian varicella virus infection of rhesus macaques recapitulates essential features of varicella zoster virus infection in humans. PLoS Pathog 5:e1000657","DOI":"10.1371\/journal.ppat.1000657"},{"key":"255_CR35","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1073\/pnas.90.1.104","volume":"90","author":"ES Mocarski","year":"1993","unstructured":"Mocarski ES, Bonyhadi M, Salimi S, McCune JM, Kaneshima H (1993) Human cytomegalovirus in a SCID-hu mouse: thymic epithelial cells are prominent targets of viral replication. Proc Natl Acad Sci USA 90:104\u2013108","journal-title":"Proc Natl Acad Sci USA"},{"key":"255_CR36","doi-asserted-by":"publisher","first-page":"5236","DOI":"10.1128\/jvi.69.9.5236-5242.1995","volume":"69","author":"JF Moffat","year":"1995","unstructured":"Moffat JF, Stein MD, Kaneshima H, Arvin AM (1995) Tropism of varicella-zoster virus for human CD4+ and CD8+ T lymphocytes and epidermal cells in SCID-hu mice. J Virol 69:5236\u20135242","journal-title":"J Virol"},{"key":"255_CR37","doi-asserted-by":"publisher","first-page":"965","DOI":"10.1128\/JVI.72.2.965-974.1998","volume":"72","author":"JF Moffat","year":"1998","unstructured":"Moffat JF, Zerboni L, Kinchington PR, Grose C, Kaneshima H, Arvin AM (1998a) Attenuation of the vaccine Oka strain of varicella-zoster virus and role of glycoprotein C in alphaherpesvirus virulence demonstrated in the SCID-hu mouse. J Virol 72:965\u2013974","journal-title":"J Virol"},{"key":"255_CR38","doi-asserted-by":"publisher","first-page":"11969","DOI":"10.1073\/pnas.95.20.11969","volume":"95","author":"JF Moffat","year":"1998","unstructured":"Moffat JF, Zerboni L, Sommer MH, Heineman TC, Cohen JI, Kaneshima H, Arvin AM (1998b) The ORF47 and ORF66 putative protein kinases of varicella-zoster virus determine tropism for human T cells and skin in the SCID-hu mouse. Proc Natl Acad Sci USA 95:11969\u201311974","journal-title":"Proc Natl Acad Sci USA"},{"key":"255_CR39","doi-asserted-by":"publisher","first-page":"8468","DOI":"10.1128\/JVI.76.16.8468-8471.2002","volume":"76","author":"J Moffat","year":"2002","unstructured":"Moffat J, Ito H, Sommer M, Taylor S, Arvin AM (2002) Glycoprotein I of varicella-zoster virus is required for viral replication in skin and T cells. J Virol 76:8468\u20138471","journal-title":"J Virol"},{"key":"255_CR40","doi-asserted-by":"publisher","first-page":"27","DOI":"10.4103\/0976-0105.177703","volume":"7","author":"AB Nair","year":"2016","unstructured":"Nair AB, Jacob S (2016) A simple practice guide for dose conversion between animals and human. J Basic Clin Pharm 7:27\u201331","journal-title":"J Basic Clin Pharm"},{"key":"255_CR41","doi-asserted-by":"publisher","first-page":"1684","DOI":"10.1126\/science.3201256","volume":"242","author":"R Namikawa","year":"1988","unstructured":"Namikawa R, Kaneshima H, Lieberman M, Weissman IL, McCune JM (1988) Infection of the SCID-hu mouse by HIV-1. Science 242:1684\u20131686","journal-title":"Science"},{"key":"255_CR42","doi-asserted-by":"publisher","first-page":"6062","DOI":"10.1128\/JVI.77.10.6062-6065.2003","volume":"77","author":"T Niizuma","year":"2003","unstructured":"Niizuma T, Zerboni L, Sommer MH, Ito H, Hinchliffe S, Arvin AM (2003) Construction of varicella-zoster virus recombinants from parent Oka cosmids and demonstration that ORF65 protein is dispensable for infection of human skin and T cells in the SCID-hu mouse model. J Virol 77:6062\u20136065","journal-title":"J Virol"},{"key":"255_CR43","doi-asserted-by":"publisher","first-page":"182","DOI":"10.1016\/j.jviromet.2008.07.033","volume":"154","author":"SL Oliver","year":"2008","unstructured":"Oliver SL, Zerboni L, Sommer M, Rajamani J, Arvin AM (2008) Development of recombinant varicella-zoster viruses expressing luciferase fusion proteins for live in vivo imaging in human skin and dorsal root ganglia xenografts. J Virol Methods 154:182\u2013193","journal-title":"J Virol Methods"},{"key":"255_CR44","doi-asserted-by":"publisher","first-page":"S88","DOI":"10.1093\/infdis\/jiy420","volume":"218","author":"NP Patel","year":"2018","unstructured":"Patel NP, Vukmanovic-Stejic M, Suarez-Farinas M, Chambers ES, Sandhu D, Fuentes-Duculan J, Mabbott NA, Rustin MHA, Krueger J, Akbar AN (2018) Impact of zostavax vaccination on T-cell accumulation and cutaneous gene expression in the skin of older humans after varicella zoster virus antigen-specific challenge. J Infect Dis 218:S88\u2013S98","journal-title":"J Infect Dis"},{"key":"255_CR45","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1038\/s41586-019-1652-y","volume":"574","author":"D-M Popescu","year":"2019","unstructured":"Popescu D-M, Botting RA, Stephenson E, Green K, Webb S, Jardine L, Calderbank EF, Polanski K, Goh I, Efremova M, Acres M, Maunder D, Vegh P, Gitton Y, Park J-E, Vento-Tormo R, Miao Z, Dixon D, Rowell R, McDonald D, Fletcher J, Poyner E, Reynolds G, Mather M, Moldovan C, Mamanova L, Greig F, Young MD, Meyer KB, Lisgo S, Bacardit J, Fuller A, Millar B, Innes B, Lindsay S, Stubbington MJT, Kowalczyk MS, Li B, Ashenberg O, Tabaka M, Dionne D, Tickle TL, Slyper M, Rozenblatt-Rosen O, Filby A, Carey P, Villani A-C, Roy A, Regev A, Ch\u00e9dotal A et al (2019) Decoding human fetal liver haematopoiesis. Nature 574:365\u2013371","journal-title":"Nature"},{"key":"255_CR46","doi-asserted-by":"publisher","first-page":"3971","DOI":"10.1128\/JVI.02592-07","volume":"82","author":"M Reichelt","year":"2008","unstructured":"Reichelt M, Zerboni L, Arvin AM (2008) Mechanisms of varicella-zoster virus neuropathogenesis in human dorsal root ganglia. J Virol 82:3971\u20133983","journal-title":"J Virol"},{"key":"255_CR47","doi-asserted-by":"crossref","unstructured":"Reichelt M, Wang L, Sommer M, Perrino J, Nour AM, Sen N, Baiker A, Zerboni L, Arvin AM (2011) Entrapment of viral capsids in nuclear PML cages is an intrinsic antiviral host defense against varicella-zoster virus. PLoS Pathog 7:e1001266","DOI":"10.1371\/journal.ppat.1001266"},{"key":"255_CR48","doi-asserted-by":"publisher","first-page":"276","DOI":"10.1016\/j.antiviral.2010.03.007","volume":"86","author":"J Rowe","year":"2010","unstructured":"Rowe J, Greenblatt RJ, Liu D, Moffat JF (2010) Compounds that target host cell proteins prevent varicella-zoster virus replication in culture, ex vivo, and in SCID-Hu mice. Antiviral Res 86:276\u2013285","journal-title":"Antiviral Res"},{"key":"255_CR49","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1002\/jnr.490260110","volume":"26","author":"C Sadzot-Delvaux","year":"1990","unstructured":"Sadzot-Delvaux C, Merville-Louis MP, Delree P, Marc P, Piette J, Moonen G, Rentier B (1990) An in vivo model of varicella-zoster virus latent infection of dorsal root ganglia. J Neurosci Res 26:83\u201389","journal-title":"J Neurosci Res"},{"key":"255_CR50","doi-asserted-by":"publisher","first-page":"306","DOI":"10.1006\/viro.2000.0507","volume":"275","author":"RA Santos","year":"2000","unstructured":"Santos RA, Hatfield CC, Cole NL, Padilla JA, Moffat JF, Arvin AM, Ruyechan WT, Hay J, Grose C (2000) Varicella-zoster virus gE escape mutant VZV-MSP exhibits an accelerated cell-to-cell spread phenotype in both infected cell cultures and SCID-hu mice. Virology 275:306\u2013317","journal-title":"Virology"},{"key":"255_CR51","doi-asserted-by":"publisher","first-page":"3284","DOI":"10.1128\/JVI.03375-14","volume":"90","author":"N Sen","year":"2016","unstructured":"Sen N, Arvin AM (2016) Dissecting the molecular mechanisms of the tropism of varicella-zoster virus for human T cells. J Virol 90:3284\u20133287","journal-title":"J Virol"},{"key":"255_CR52","doi-asserted-by":"crossref","unstructured":"Shibata S, Asano T, Ogura A, Hashimoto N, Hayakawa J, Uetsuka K, Nakayama H, Doi K (1997) SCID-bg mice as xenograft recipients. Lab Anim 31:163\u2013168","DOI":"10.1258\/002367797780600107"},{"key":"255_CR53","doi-asserted-by":"publisher","first-page":"1875","DOI":"10.1086\/379835","volume":"188","author":"K Shiraki","year":"2003","unstructured":"Shiraki K, Yoshida Y, Asano Y, Yamanishi K, Takahashi M (2003) Pathogenetic tropism of varicella-zoster virus to primary human hepatocytes and attenuating tropism of Oka varicella vaccine strain to neonatal dermal fibroblasts. J Infect Dis 188:1875\u20131877","journal-title":"J Infect Dis"},{"key":"255_CR54","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1038\/nri2017","volume":"7","author":"LD Shultz","year":"2007","unstructured":"Shultz LD, Ishikawa F, Greiner DL (2007) Humanized mice in translational biomedical research. Nat Rev Immunol 7:118\u2013130","journal-title":"Nat Rev Immunol"},{"key":"255_CR55","doi-asserted-by":"publisher","first-page":"786","DOI":"10.1038\/nri3311","volume":"12","author":"LD Shultz","year":"2012","unstructured":"Shultz LD, Brehm MA, Garcia-Martinez JV, Greiner DL (2012) Humanized mice for immune system investigation: progress, promise and challenges. Nat Rev Immunol 12:786\u2013798","journal-title":"Nat Rev Immunol"},{"key":"255_CR56","first-page":"211","volume":"342","author":"M Steain","year":"2010","unstructured":"Steain M, Slobedman B, Abendroth A (2010) Experimental models to study varicella-zoster virus infection of neurons. Curr Top Microbiol Immunol 342:211\u2013228","journal-title":"Curr Top Microbiol Immunol"},{"key":"255_CR57","doi-asserted-by":"crossref","unstructured":"Stoddart CA, Bales CA, Bare JC, Chkhenkeli G, Galkina SA, Kinkade AN, Moreno ME, Rivera JM, Ronquillo RE, Sloan B, Black PL (2007) Validation of the SCID-hu Thy\/Liv mouse model with four classes of licensed antiretrovirals. PLoS One 2:e655","DOI":"10.1371\/journal.pone.0000655"},{"key":"255_CR58","doi-asserted-by":"publisher","first-page":"11501","DOI":"10.1128\/JVI.79.17.11501-11506.2005","volume":"79","author":"SL Taylor","year":"2005","unstructured":"Taylor SL, Moffat JF (2005) Replication of varicella-zoster virus in human skin organ culture. J Virol 79:11501\u201311506","journal-title":"J Virol"},{"key":"255_CR59","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1128\/JVI.01338-09","volume":"84","author":"SE Vleck","year":"2010","unstructured":"Vleck SE, Oliver SL, Reichelt M, Rajamani J, Zerboni L, Jones C, Zehnder J, Grose C, Arvin AM (2010) Anti-glycoprotein H antibody impairs the pathogenicity of varicella-zoster virus in skin xenografts in the SCID mouse model. J Virol 84:141\u2013152","journal-title":"J Virol"},{"key":"255_CR60","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1002\/jmv.1890210108","volume":"21","author":"A Vonsover","year":"1987","unstructured":"Vonsover A, Leventon-Kriss S, Langer A, Smetana Z, Zaizov R, Potaznick D, Cohen IJ, Gotlieb-Stematsky T (1987) Detection of varicella-zoster virus in lymphocytes by DNA hybridization. J Med Virol 21:57\u201366","journal-title":"J Med Virol"},{"key":"255_CR61","doi-asserted-by":"publisher","first-page":"977","DOI":"10.4049\/jimmunol.1201331","volume":"190","author":"M Vukmanovic-Stejic","year":"2013","unstructured":"Vukmanovic-Stejic M, Sandhu D, Sobande TO, Agius E, Lacy KE, Riddell N, Montez S, Dintwe OB, Scriba TJ, Breuer J, Nikolich-Zugich J, Ogg G, Rustin MH, Akbar AN (2013) Varicella zoster-specific CD4+Foxp3+ T cells accumulate after cutaneous antigen challenge in humans. J Immunol 190:977\u2013986","journal-title":"J Immunol"},{"key":"255_CR62","doi-asserted-by":"publisher","first-page":"1752","DOI":"10.1038\/jid.2015.63","volume":"135","author":"M Vukmanovic-Stejic","year":"2015","unstructured":"Vukmanovic-Stejic M, Sandhu D, Seidel JA, Patel N, Sobande TO, Agius E, Jackson SE, Fuentes-Duculan J, Suarez-Farinas M, Mabbott NA, Lacy KE, Ogg G, Nestle FO, Krueger JG, Rustin MHA, Akbar AN (2015) The characterization of varicella zoster virus-specific T cells in skin and blood during Aging. J Invest Dermatol 135:1752\u20131762","journal-title":"J Invest Dermatol"},{"key":"255_CR63","doi-asserted-by":"publisher","first-page":"844","DOI":"10.1016\/j.jaci.2017.10.032","volume":"142","author":"M Vukmanovic-Stejic","year":"2018","unstructured":"Vukmanovic-Stejic M, Chambers ES, Suarez-Farinas M, Sandhu D, Fuentes-Duculan J, Patel N, Agius E, Lacy KE, Turner CT, Larbi A, Birault V, Noursadeghi M, Mabbott NA, Rustin MHA, Krueger JG, Akbar AN (2018) Enhancement of cutaneous immunity during aging by blocking p38 mitogen-activated protein (MAP) kinase-induced inflammation. J Allergy Clin Immunol 142:844\u2013856","journal-title":"J Allergy Clin Immunol"},{"key":"255_CR64","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1016\/j.antiviral.2017.08.012","volume":"146","author":"W Wang","year":"2017","unstructured":"Wang W, Pan D, Fu W, Cai L, Ye J, Liu J, Liu C, Huang X, Lin Y, Xia N, Cheng T, Zhu H (2017) A SCID mouse-human lung xenograft model of varicella-zoster virus infection. Antiviral Res 146:45\u201353","journal-title":"Antiviral Res"},{"key":"255_CR65","doi-asserted-by":"publisher","first-page":"340","DOI":"10.3181\/00379727-83-20354","volume":"83","author":"TH Weller","year":"1953","unstructured":"Weller TH (1953) Serial propagation in vitro of agents producing inclusion bodies derived from varicella and herpes zoster. Proc Soc Exp Biol Med 83:340\u2013346","journal-title":"Proc Soc Exp Biol Med"},{"key":"255_CR66","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1016\/j.virol.2004.10.047","volume":"332","author":"L Zerboni","year":"2005","unstructured":"Zerboni L, Hinchliffe S, Sommer MH, Ito H, Besser J, Stamatis S, Cheng J, Distefano D, Kraiouchkine N, Shaw A, Arvin AM (2005a) Analysis of varicella zoster virus attenuation by evaluation of chimeric parent Oka\/vaccine Oka recombinant viruses in skin xenografts in the SCIDhu mouse model. Virology 332:337\u2013346","journal-title":"Virology"},{"key":"255_CR67","doi-asserted-by":"publisher","first-page":"6490","DOI":"10.1073\/pnas.0501045102","volume":"102","author":"L Zerboni","year":"2005","unstructured":"Zerboni L, Ku CC, Jones CD, Zehnder JL, Arvin AM (2005b) Varicella-zoster virus infection of human dorsal root ganglia in vivo. Proc Natl Acad Sci U S A 102:6490\u20136495","journal-title":"Proc Natl Acad Sci U S A"},{"key":"255_CR68","doi-asserted-by":"publisher","first-page":"14086","DOI":"10.1073\/pnas.0706023104","volume":"104","author":"L Zerboni","year":"2007","unstructured":"Zerboni L, Reichelt M, Jones CD, Zehnder JL, Ito H, Arvin AM (2007) Aberrant infection and persistence of varicella-zoster virus in human dorsal root ganglia in vivo in the absence of glycoprotein I. Proc Natl Acad Sci USA 104:14086\u201314091","journal-title":"Proc Natl Acad Sci USA"},{"key":"255_CR69","first-page":"255","volume":"342","author":"L Zerboni","year":"2010","unstructured":"Zerboni L, Reichelt M, Arvin A (2010) Varicella-zoster virus neurotropism in SCID mouse-human dorsal root ganglia xenografts. Curr Top Microbiol Immunol 342:255\u2013276","journal-title":"Curr Top Microbiol Immunol"},{"key":"255_CR70","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1128\/JVI.01902-10","volume":"85","author":"L Zerboni","year":"2011","unstructured":"Zerboni L, Berarducci B, Rajamani J, Jones CD, Zehnder JL, Arvin A (2011) Varicella-zoster virus glycoprotein E is a critical determinant of virulence in the SCID mouse-human model of neuropathogenesis. J Virol 85:98\u2013111","journal-title":"J Virol"},{"key":"255_CR71","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1038\/nrmicro3215","volume":"12","author":"L Zerboni","year":"2014","unstructured":"Zerboni L, Sen N, Oliver SL, Arvin AM (2014) Molecular mechanisms of varicella zoster virus pathogenesis. Nat Rev Microbiol 12:197\u2013210","journal-title":"Nat Rev Microbiol"},{"key":"255_CR72","doi-asserted-by":"crossref","unstructured":"Zerboni L, Arvin A (2015) Neuronal subtype and satellite cell tropism are determinants of varicella-zoster virus virulence in human dorsal root ganglia xenografts in vivo. PLoS Pathog 11:e1004989","DOI":"10.1371\/journal.ppat.1004989"},{"key":"255_CR73","doi-asserted-by":"crossref","unstructured":"Zerboni L, Sung P, Lee G, Arvin A (2018) Age-associated differences in infection of human skin in the SCID mouse model of varicella-zoster virus pathogenesis. J Virol 92","DOI":"10.1128\/JVI.00002-18"},{"key":"255_CR74","doi-asserted-by":"publisher","first-page":"9024","DOI":"10.1128\/JVI.02666-06","volume":"81","author":"Z Zhang","year":"2007","unstructured":"Zhang Z, Rowe J, Wang W, Sommer M, Arvin A, Moffat J, Zhu H (2007) Genetic analysis of varicella-zoster virus ORF0 to ORF4 by use of a novel luciferase bacterial artificial chromosome system. J Virol 81:9024\u20139033","journal-title":"J Virol"}],"container-title":["Current Topics in Microbiology and Immunology","Varicella-zoster Virus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/82_2022_255","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,11,11]],"date-time":"2022-11-11T15:33:34Z","timestamp":1668180814000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/82_2022_255"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022]]},"ISBN":["9783031153044","9783031153051"],"references-count":74,"URL":"https:\/\/doi.org\/10.1007\/82_2022_255","relation":{},"ISSN":["0070-217X","2196-9965"],"issn-type":[{"type":"print","value":"0070-217X"},{"type":"electronic","value":"2196-9965"}],"subject":[],"published":{"date-parts":[[2022]]},"assertion":[{"value":"16 March 2022","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}}]}}