{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T00:43:44Z","timestamp":1768869824547,"version":"3.49.0"},"publisher-location":"New York, NY","reference-count":24,"publisher":"Springer US","isbn-type":[{"value":"9781071614792","type":"print"},{"value":"9781071614808","type":"electronic"}],"license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021]]},"DOI":"10.1007\/978-1-0716-1480-8_9","type":"book-chapter","created":{"date-parts":[[2021,7,30]],"date-time":"2021-07-30T16:03:40Z","timestamp":1627661020000},"page":"77-85","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Laser-Induced Choroidal Neovascularization in Rats"],"prefix":"10.1007","author":[{"given":"Min","family":"Zhao","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wankun","family":"Xie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Travis W.","family":"Hein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lih","family":"Kuo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr","given":"Robert H.","family":"Rosa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,7,31]]},"reference":[{"key":"9_CR1","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1016\/j.preteyeres.2010.09.003","volume":"30","author":"E Stefansson","year":"2011","unstructured":"Stefansson E, Geirsdottir A, Sigurdsson H (2011) Metabolic physiology in age related macular degeneration. Prog Retin Eye Res 30:72\u201380","journal-title":"Prog Retin Eye Res"},{"key":"9_CR2","doi-asserted-by":"publisher","first-page":"2606","DOI":"10.1056\/NEJMra0801537","volume":"358","author":"RD Jager","year":"2008","unstructured":"Jager RD, Mieler WF, Miller JW (2008) Age-related macular degeneration. N Engl J Med 358:2606\u20132617","journal-title":"N Engl J Med"},{"key":"9_CR3","first-page":"3512","volume":"17","author":"X Wankun","year":"2011","unstructured":"Wankun X, Wenzhen Y, Min Z et al (2011) Protective effect of paeoniflorin against oxidative stress in human retinal pigment epithelium in vitro. Mol Vis 17:3512\u20133522","journal-title":"Mol Vis"},{"key":"9_CR4","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0125150","volume":"10","author":"M Zhao","year":"2015","unstructured":"Zhao M, Bai Y, Xie W et al (2015) Interleukin-1\u03b2 level is increased in vitreous of patients with neovascular age-related macular degeneration (nAMD) and polypoidal choroidal vasculopathy (PCV). PLoS One 10:e0125150","journal-title":"PLoS One"},{"key":"9_CR5","first-page":"353","volume":"58","author":"JZ Nowak","year":"2006","unstructured":"Nowak JZ (2006) Age-related macular degeneration (AMD): pathogenesis and therapy. Pharmacol Rep 58:353\u2013363","journal-title":"Pharmacol Rep"},{"key":"9_CR6","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1016\/0039-6257(88)90052-5","volume":"32","author":"NM Bressler","year":"1988","unstructured":"Bressler NM, Bressler SB, Fine SL (1988) Age-related macular degeneration. Surv Ophthalmol 32:375\u2013413","journal-title":"Surv Ophthalmol"},{"key":"9_CR7","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/3164734","volume":"2016","author":"M Nita","year":"2016","unstructured":"Nita M, Grzybowski A (2016) The role of the reactive oxygen species and oxidative stress in the pathomechanism of the age-related ocular diseases and other pathologies of the anterior and posterior eye segments in adults. Oxidative Med Cell Longev 2016:3164734","journal-title":"Oxidative Med Cell Longev"},{"key":"9_CR8","doi-asserted-by":"publisher","first-page":"2197","DOI":"10.1038\/nprot.2013.135","volume":"8","author":"V Lambert","year":"2013","unstructured":"Lambert V, Lecomte J, Hansen S et al (2013) Laser-induced choroidal neovascularization model to study age-related macular degeneration in mice. Nat Protoc 8:2197\u20132211","journal-title":"Nat Protoc"},{"key":"9_CR9","doi-asserted-by":"publisher","first-page":"500","DOI":"10.1016\/j.preteyeres.2010.05.003","volume":"29","author":"HE Grossniklaus","year":"2010","unstructured":"Grossniklaus HE, Kang SJ, Berglin L (2010) Animal models of choroidal and retinal neovascularization. Prog Retin Eye Res 29:500\u2013519","journal-title":"Prog Retin Eye Res"},{"key":"9_CR10","doi-asserted-by":"publisher","first-page":"264","DOI":"10.1001\/archopht.1989.01070010270035","volume":"107","author":"ET Dobi","year":"1989","unstructured":"Dobi ET, Puliafito CA, Destro M (1989) A new model of experimental choroidal neovascularization in the rat. Arch Ophthalmol 107:264\u2013269","journal-title":"Arch Ophthalmol"},{"key":"9_CR11","doi-asserted-by":"publisher","first-page":"200","DOI":"10.1159\/000063886","volume":"34","author":"AM Kuroki","year":"2002","unstructured":"Kuroki AM, Bhutto IA, Kitaoka T et al (2002) Natural course of experimental choroidal neovascularization: three-dimensional study with corrosion cast and scanning electron microscope. Ophthalmic Res 34:200\u2013205","journal-title":"Ophthalmic Res"},{"key":"9_CR12","doi-asserted-by":"publisher","first-page":"5349","DOI":"10.1167\/iovs.02-0732","volume":"44","author":"I Semkova","year":"2003","unstructured":"Semkova I, Peters S, Welsandt G et al (2003) Investigation of laser-induced choroidal neovascularization in the rat. Invest Ophthalmol Vis Sci 44:5349\u20135354","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"9_CR13","first-page":"e53502","volume":"106","author":"RS Shah","year":"2015","unstructured":"Shah RS, Soetikno BT, Lajko M et al (2015) A mouse model for laser-induced choroidal neovascularization. J Vis Exp 106:e53502","journal-title":"J Vis Exp"},{"key":"9_CR14","doi-asserted-by":"publisher","first-page":"697","DOI":"10.1111\/j.1600-0420.2005.00566.x","volume":"83","author":"JF Kiilgaard","year":"2005","unstructured":"Kiilgaard JF, Andersen MV, Wiencke AK et al (2005) A new animal model of choroidal neovascularization. Acta Ophthalmol Scand 83:697\u2013704","journal-title":"Acta Ophthalmol Scand"},{"key":"9_CR15","doi-asserted-by":"publisher","first-page":"464","DOI":"10.1016\/j.exer.2011.03.006","volume":"92","author":"RJ Goody","year":"2011","unstructured":"Goody RJ, Hu W, Shafiee A et al (2011) Optimization of laser-induced choroidal neovascularization in African green monkeys. Exp Eye Res 92:464\u2013472","journal-title":"Exp Eye Res"},{"key":"9_CR16","first-page":"707","volume":"77","author":"SJ Ryan","year":"1979","unstructured":"Ryan SJ (1979) The development of an experimental model of subretinal neovascularization in disciform macular degeneration. Trans Am Ophthalmol Soc 77:707\u2013745","journal-title":"Trans Am Ophthalmol Soc"},{"key":"9_CR17","first-page":"37","volume":"14","author":"M Zhang","year":"2008","unstructured":"Zhang M, Zhang J, Yan M et al (2008) Recombinant anti-vascular endothelial growth factor fusion protein efficiently suppresses choridal neovasularization in monkeys. Mol Vis 14:37\u201349","journal-title":"Mol Vis"},{"key":"9_CR18","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1001\/archopht.118.1.78","volume":"118","author":"MJ Tolentino","year":"2000","unstructured":"Tolentino MJ, Husain D, Theodosiadis P et al (2000) Angiography of fluoresceinated anti-vascular endothelial growth factor antibody and dextrans in experimental choroidal neovascularization. Arch Ophthalmol 118:78\u201384","journal-title":"Arch Ophthalmol"},{"key":"9_CR19","doi-asserted-by":"publisher","first-page":"353","DOI":"10.1001\/archopht.122.3.353","volume":"122","author":"WY Shen","year":"2004","unstructured":"Shen WY, Lee SY, Yeo I et al (2004) Predilection of the macular region to high incidence of choroidal neovascularization after intense laser photocoagulation in the monkey. Arch Ophthalmol 122:353\u2013360","journal-title":"Arch Ophthalmol"},{"key":"9_CR20","doi-asserted-by":"publisher","first-page":"1019","DOI":"10.1016\/j.dib.2018.10.123","volume":"21","author":"W Xie","year":"2018","unstructured":"Xie W, Zhao M, Tsai SH et al (2018) Data on SD-OCT image acquisition, ultrastructural features, and horizontal tissue shrinkage in the porcine retina. Data Brief 21:1019\u20131025","journal-title":"Data Brief"},{"key":"9_CR21","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1016\/j.exer.2018.08.003","volume":"177","author":"W Xie","year":"2018","unstructured":"Xie W, Zhao M, Tsai SH et al (2018) Correlation of spectral domain optical coherence tomography with histology and electron microscopy in the porcine retina. Exp Eye Res 177:181\u2013190","journal-title":"Exp Eye Res"},{"key":"9_CR22","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1046\/j.1463-5224.1999.00077.x","volume":"2","author":"MJ Chandler","year":"1999","unstructured":"Chandler MJ, Smith PJ, Samuelson DA et al (1999) Photoreceptor density of the domestic pig retina. Vet Ophthalmol 2:179\u2013184","journal-title":"Vet Ophthalmol"},{"key":"9_CR23","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1007\/s004170000205","volume":"239","author":"T Fukuchi","year":"2001","unstructured":"Fukuchi T, Takahashi K, Shou K et al (2001) Optical coherence tomography (OCT) findings in normal retina and laser-induced choroidal neovascularization in rats. Graefes Arch Clin Exp Ophthalmol 239:41\u201346","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"9_CR24","doi-asserted-by":"publisher","first-page":"1125","DOI":"10.1167\/iovs.17-23083","volume":"59","author":"M Zhao","year":"2018","unstructured":"Zhao M, Xie W, Tsai SH et al (2018) Intravitreal stanniocalcin-1 enhances new blood vessel growth in a rat model of laser-induced choroidal neovascularization. Invest Ophthalmol Vis Sci 59:1125\u20131133","journal-title":"Invest Ophthalmol Vis Sci"}],"container-title":["Methods in Molecular Biology","Cardiovascular Development"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/978-1-0716-1480-8_9","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,30]],"date-time":"2021-07-30T16:04:03Z","timestamp":1627661043000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/978-1-0716-1480-8_9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021]]},"ISBN":["9781071614792","9781071614808"],"references-count":24,"URL":"https:\/\/doi.org\/10.1007\/978-1-0716-1480-8_9","relation":{},"ISSN":["1064-3745","1940-6029"],"issn-type":[{"value":"1064-3745","type":"print"},{"value":"1940-6029","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021]]},"assertion":[{"value":"31 July 2021","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}}]}}