{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,26]],"date-time":"2025-03-26T10:11:54Z","timestamp":1742983914351,"version":"3.40.3"},"publisher-location":"New York, NY","reference-count":36,"publisher":"Springer US","isbn-type":[{"type":"print","value":"9781071619704"},{"type":"electronic","value":"9781071619711"}],"license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022]]},"DOI":"10.1007\/978-1-0716-1971-1_18","type":"book-chapter","created":{"date-parts":[[2022,5,26]],"date-time":"2022-05-26T18:12:23Z","timestamp":1653588743000},"page":"215-234","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Analysis of Salmonella Typhi Pathogenesis in a Humanized Mouse Model"],"prefix":"10.1007","author":[{"given":"Taylor A.","family":"Stepien","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen J.","family":"Libby","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joyce E.","family":"Karlinsey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael A.","family":"Brehm","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dale L.","family":"Greiner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leonard D.","family":"Shultz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thea","family":"Brabb","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ferric C.","family":"Fang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,5,27]]},"reference":[{"key":"18_CR1","doi-asserted-by":"publisher","first-page":"S59","DOI":"10.1093\/cid\/ciaa236","volume":"71","author":"N Duff","year":"2020","unstructured":"Duff N, Steele AD, Garrett D (2020) Global action for local impact: the 11th international conference on typhoid and other invasive Salmonelloses. Clin Infect Dis 71:S59\u2013S63","journal-title":"Clin Infect Dis"},{"key":"18_CR2","doi-asserted-by":"crossref","unstructured":"Santos RL, Zhang S, Tsolis RM et al (2001) Animal models of Salmonella infections: enteritis versus typhoid fever. Microbes Infect 3:1335\u20131344","DOI":"10.1016\/S1286-4579(01)01495-2"},{"key":"18_CR3","doi-asserted-by":"crossref","unstructured":"Johnson R, Ravenhall M, Pickard D et al (2018) Comparison of Salmonella enterica serovars Typhi and Typhimurium reveals typhoidal serovar-specific responses to bile. Infect Immun 86:e00490-17","DOI":"10.1128\/IAI.00490-17"},{"key":"18_CR4","doi-asserted-by":"crossref","unstructured":"Sabbagh SC, Lepage C, McClelland M et al (2012) Selection of Salmonella enterica serovar Typhi genes involved during interaction with human macrophages by screening of a transposon mutant library. PLoS One 7:e36643","DOI":"10.1371\/journal.pone.0036643"},{"key":"18_CR5","doi-asserted-by":"crossref","unstructured":"Gal-Mor O, Boyle EC, Grassl GA (2014) Same species, different diseases: how and why typhoidal and non-typhoidal Salmonella enterica serovars differ. Front Microbiol 5:391","DOI":"10.3389\/fmicb.2014.00391"},{"key":"18_CR6","doi-asserted-by":"publisher","first-page":"323","DOI":"10.1146\/annurev.iy.09.040191.001543","volume":"9","author":"MJ Bosma","year":"1991","unstructured":"Bosma MJ, Carroll AM (1991) The SCID mouse mutant: definition, characterization, and potential uses. Annu Rev Immunol 9:323\u2013350","journal-title":"Annu Rev Immunol"},{"key":"18_CR7","doi-asserted-by":"crossref","unstructured":"Mombaerts P, Iacomini J, Johnson RS et al (2018) RAG-1-deficient mice have no mature B and T lymphocytes. Cell 68(5):869\u2013877. https:\/\/pubmed.ncbi.nlm.nih.gov\/1547488\/","DOI":"10.1016\/0092-8674(92)90030-G"},{"key":"18_CR8","doi-asserted-by":"crossref","unstructured":"Shinkai Y, Rathburn G, Lam KP et al (1992) RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement. Cell 68(5):855\u2013867. https:\/\/pubmed.ncbi.nlm.nih.gov\/1547487\/","DOI":"10.1016\/0092-8674(92)90029-C"},{"key":"18_CR9","doi-asserted-by":"publisher","first-page":"2556","DOI":"10.1182\/blood.V92.7.2556","volume":"92","author":"JC van der Loo","year":"1998","unstructured":"van der Loo JC, Hanenberg H, Cooper RJ et al (1998) Nonobese diabetic\/severe combined immunodeficiency (NOD\/SCID) mouse as a model system to study the engraftment and mobilization of human peripheral blood stem cells. Blood 92:2556\u20132570","journal-title":"Blood"},{"key":"18_CR10","doi-asserted-by":"publisher","first-page":"3175","DOI":"10.1182\/blood-2001-12-0207","volume":"100","author":"M Ito","year":"2002","unstructured":"Ito M, Hiramatsu H, Kobayashi K et al (2002) NOD\/SCID\/gamma(c)(null) mouse: an excellent recipient mouse model for engraftment of human cells. Blood 100:3175\u20133182","journal-title":"Blood"},{"key":"18_CR11","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1016\/j.clim.2009.12.008","volume":"135","author":"MA Brehm","year":"2010","unstructured":"Brehm MA, Cuthbert A, Yang C et al (2010) Parameters for establishing humanized mouse models to study human immunity: analysis of human hematopoietic stem cell engraftment in three immunodeficient strains of mice bearing the IL2rgamma(null) mutation. Clin Immunol 135:84\u201398","journal-title":"Clin Immunol"},{"key":"18_CR12","doi-asserted-by":"crossref","unstructured":"Libby SJ, Brehm MA, Greiner DL et al (2010) Humanized nonobese diabetic-scid IL2r\u03b3null mice are susceptible to lethal Salmonella Typhi infection. Proc Natl Acad Sci U S A 107:15589\u201315594","DOI":"10.1073\/pnas.1005566107"},{"key":"18_CR13","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1007\/s00005-018-0506-x","volume":"66","author":"KSM Yong","year":"2018","unstructured":"Yong KSM, Her Z, Chen Q (2018) Humanized mice as unique tools for human-specific studies. Arch Immunol Ther Exp 66:245\u2013266","journal-title":"Arch Immunol Ther Exp"},{"key":"18_CR14","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1007\/s00335-019-09796-2","volume":"30","author":"LD Shultz","year":"2019","unstructured":"Shultz LD, Keck J, Burzenski L et al (2019) Humanized mouse models of immunological diseases and precision medicine. Mamm Genome 30:123\u2013142","journal-title":"Mamm Genome"},{"key":"18_CR15","doi-asserted-by":"crossref","unstructured":"Song J, Willinger T, Rongvaux A et al (2010) A mouse model for the human pathogen Salmonella Typhi. Cell Host Microbe 8:369\u2013376","DOI":"10.1016\/j.chom.2010.09.003"},{"key":"18_CR16","doi-asserted-by":"crossref","unstructured":"Firoz Mian M, Pek EA, Chenoweth MJ et al (2011) Humanized mice are susceptible to Salmonella Typhi infection. Cell Mol Immunol 8:83\u201387","DOI":"10.1038\/cmi.2010.52"},{"key":"18_CR17","doi-asserted-by":"crossref","unstructured":"Pearson T, Greiner DL, Shultz LD (2008) Creation of \u201chumanized\u201d mice to study human immunity. Curr Protoc Immunol. Chapter 15:Unit 15.21","DOI":"10.1002\/0471142735.im1521s81"},{"key":"18_CR18","doi-asserted-by":"crossref","unstructured":"Vladoianu IR, Chang HR, Pech\u00e8re JC (1990) Expression of host resistance to Salmonella typhi and Salmonella typhimurium: bacterial survival within macrophages of murine and human origin. Microb Pathog 8:83\u201390","DOI":"10.1016\/0882-4010(90)90072-X"},{"key":"18_CR19","doi-asserted-by":"crossref","unstructured":"Ishibashi Y, Arai T (1995) Salmonella typhi does not inhibit phagosome-lysosome fusion in human monocyte-derived macrophages. FEMS Immunol Med Microbiol 12:55\u201361","DOI":"10.1111\/j.1574-695X.1995.tb00175.x"},{"key":"18_CR20","doi-asserted-by":"crossref","unstructured":"Schwan WR, Huang XZ, Hu L et al (2000) Differential bacterial survival, replication, and apoptosis-inducing ability of Salmonella serovars within human and murine macrophages. Infect Immun 68:1005\u20131013","DOI":"10.1128\/IAI.68.3.1005-1013.2000"},{"key":"18_CR21","doi-asserted-by":"crossref","unstructured":"Pascopella L, Raupach B, Ghori N et al (1995) Host restriction phenotypes of Salmonella typhi and Salmonella gallinarum. Infect Immun 63:4329\u20134335","DOI":"10.1128\/iai.63.11.4329-4335.1995"},{"issue":"6","key":"18_CR22","doi-asserted-by":"publisher","first-page":"611","DOI":"10.1084\/jem.3.6.611","volume":"3","author":"FA Mallory","year":"1898","unstructured":"Mallory FA (1898) Histological study of typhoid fever. J Exp Med 3(6):611\u2013638. https:\/\/rupress.org\/jem\/article\/3\/6\/611\/7544\/A-HISTOLOGICAL-STUDY-OF-TYPHOID-FEVER","journal-title":"J Exp Med"},{"key":"18_CR23","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1159\/000204357","volume":"18","author":"S Bharadwaj","year":"2009","unstructured":"Bharadwaj S, Anim JT, Ebrahim F et al (2009) Granulomatous inflammatory response in a case of typhoid fever. Med Princ Pract 18:239\u2013241","journal-title":"Med Princ Pract"},{"key":"18_CR24","doi-asserted-by":"publisher","first-page":"786","DOI":"10.1038\/nri3311","volume":"12","author":"LD Shultz","year":"2012","unstructured":"Shultz LD, Brehm MA, Garcia JV et al (2012) Humanized mice for immune system investigation: progress, promise and challenges. Nat Rev Immunol 12:786\u2013798","journal-title":"Nat Rev Immunol"},{"key":"18_CR25","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1016\/j.stemcr.2014.12.005","volume":"4","author":"BE McIntosh","year":"2015","unstructured":"McIntosh BE, Brown ME, Duffin BM et al (2015) Nonirradiated NOD,B6.SCID Il2r\u03b3\u2212\/\u2212 KitW41\/W41 (NBSGW) mice support multilineage engraftment of human hematopoietic cells. Stem Cell Rep 4:171\u2013180","journal-title":"Stem Cell Rep"},{"key":"18_CR26","doi-asserted-by":"crossref","unstructured":"Robbins JD, Robbins JB (1984) Reexamination of the protective role of the capsular polysaccharide (Vi antigen) of Salmonella typhi. J Infect Dis 150:436\u2013449","DOI":"10.1093\/infdis\/150.3.436"},{"key":"18_CR27","unstructured":"Looney RJ, Steigbigel RT (1986) Role of the Vi antigen of Salmonella typhi in resistance to host defense in vitro. J Lab Clin Med 108:506\u2013516"},{"key":"18_CR28","doi-asserted-by":"publisher","first-page":"848","DOI":"10.1038\/35101607","volume":"413","author":"J Parkhill","year":"2001","unstructured":"Parkhill J, Dougan G, James KD et al (2001) Complete genome sequence of a multiple drug resistant Salmonella enterica serovar Typhi CT18. Nature 413:848\u2013852","journal-title":"Nature"},{"key":"18_CR29","doi-asserted-by":"crossref","unstructured":"Richardson AR, Payne EC, Younger N et al (2011) Multiple targets of nitric oxide in the tricarboxylic acid cycle of Salmonella enterica serovar Typhimurium. Cell Host Microbe 10:33\u201343","DOI":"10.1016\/j.chom.2011.06.004"},{"key":"18_CR30","doi-asserted-by":"publisher","first-page":"6640","DOI":"10.1073\/pnas.120163297","volume":"97","author":"KA Datsenko","year":"2000","unstructured":"Datsenko KA, Wanner BL (2000) One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products. Proc Natl Acad Sci U S A 97:6640\u20136645","journal-title":"Proc Natl Acad Sci U S A"},{"key":"18_CR31","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1016\/0378-1119(91)90366-J","volume":"100","author":"RF Wang","year":"1991","unstructured":"Wang RF, Kushner SR (1991) Construction of versatile low-copy-number vectors for cloning, sequencing and gene expression in Escherichia coli. Gene 100:195\u2013199","journal-title":"Gene"},{"key":"18_CR32","doi-asserted-by":"publisher","first-page":"1141","DOI":"10.1128\/jb.134.3.1141-1156.1978","volume":"134","author":"AC Chang","year":"1978","unstructured":"Chang AC, Cohen SN (1978) Construction and characterization of amplifiable multicopy DNA cloning vehicles derived from the P15A cryptic miniplasmid. J Bacteriol 134:1141\u20131156","journal-title":"J Bacteriol"},{"key":"18_CR33","doi-asserted-by":"crossref","unstructured":"Berggren RE, Wunderlich A, Ziegler E et al (1995) HIV gp120-specific cell-mediated immune responses in mice after oral immunization with recombinant Salmonella. J Acquir Immune Defic Syndr Hum Retrovirol 10:489\u2013495","DOI":"10.1097\/00042560-199510050-00001"},{"key":"18_CR34","doi-asserted-by":"crossref","unstructured":"Karlinsey JE, Stepien TA, Mayho M et al (2019) Genome-wide analysis of Salmonella enterica serovar Typhi in humanized mice reveals key virulence features. Cell Host Microbe 26:426\u2013434.e6","DOI":"10.1016\/j.chom.2019.08.001"},{"key":"18_CR35","doi-asserted-by":"publisher","first-page":"526","DOI":"10.1038\/s41576-020-0244-x","volume":"21","author":"AK Cain","year":"2020","unstructured":"Cain AK, Barquist L, Goodman AL et al (2020) A decade of advances in transposon-insertion sequencing. Nat Rev Genet 21:526\u2013540","journal-title":"Nat Rev Genet"},{"key":"18_CR36","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1016\/S0076-6879(06)21012-7","volume":"421","author":"L Gallagher","year":"2007","unstructured":"Gallagher L, Turner C, Ramage E et al (2007) Creating recombination-activated genes and sequence-defined mutant libraries using transposons. Meth Enzymol 421:126\u2013140","journal-title":"Meth Enzymol"}],"container-title":["Methods in Molecular Biology","Bacterial Virulence"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/978-1-0716-1971-1_18","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,26]],"date-time":"2022-05-26T18:13:09Z","timestamp":1653588789000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/978-1-0716-1971-1_18"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022]]},"ISBN":["9781071619704","9781071619711"],"references-count":36,"URL":"https:\/\/doi.org\/10.1007\/978-1-0716-1971-1_18","relation":{},"ISSN":["1064-3745","1940-6029"],"issn-type":[{"type":"print","value":"1064-3745"},{"type":"electronic","value":"1940-6029"}],"subject":[],"published":{"date-parts":[[2022]]},"assertion":[{"value":"27 May 2022","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}}]}}