{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,16]],"date-time":"2025-07-16T13:41:32Z","timestamp":1752673292893,"version":"3.40.3"},"publisher-location":"New York, NY","reference-count":9,"publisher":"Springer US","isbn-type":[{"type":"print","value":"9781071627396"},{"type":"electronic","value":"9781071627402"}],"license":[{"start":{"date-parts":[[2022,11,15]],"date-time":"2022-11-15T00:00:00Z","timestamp":1668470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2022,11,15]],"date-time":"2022-11-15T00:00:00Z","timestamp":1668470400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023]]},"DOI":"10.1007\/978-1-0716-2740-2_17","type":"book-chapter","created":{"date-parts":[[2022,11,14]],"date-time":"2022-11-14T10:38:56Z","timestamp":1668422336000},"page":"283-292","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Ultrasound-Guided Intra-thymic Cell Injection"],"prefix":"10.1007","author":[{"given":"Hristo","family":"Georgiev","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura B.","family":"Chopp","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristin A.","family":"Hogquist","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,11,15]]},"reference":[{"key":"17_CR1","doi-asserted-by":"publisher","first-page":"8633","DOI":"10.1073\/pnas.85.22.8633","volume":"85","author":"J Nikoli\u0107-Zugi\u0107","year":"1988","unstructured":"Nikoli\u0107-Zugi\u0107 J, Bevan MJ (1988) Thymocytes expressing CD8 differentiate into CD4+ cells following intrathymic injection. Proc Natl Acad Sci U S A 85:8633\u20138637","journal-title":"Proc Natl Acad Sci U S A"},{"key":"17_CR2","doi-asserted-by":"publisher","first-page":"971","DOI":"10.1038\/ni710","volume":"2","author":"L Gapin","year":"2001","unstructured":"Gapin L, Matsuda JL, Surh CD, Kronenberg M (2001) NKT cells derive from double-positive thymocytes that are positively selected by CD1d. Nat Immunol 2:971\u2013978","journal-title":"Nat Immunol"},{"key":"17_CR3","doi-asserted-by":"publisher","first-page":"13116","DOI":"10.1038\/ncomms13116","volume":"7","author":"H Georgiev","year":"2016","unstructured":"Georgiev H, Ravens I, Benarafa C, F\u00f6rster R, Bernhardt G (2016) Distinct gene expression patterns correlate with developmental and functional traits of iNKT subsets. Nat Commun 7:13116","journal-title":"Nat Commun"},{"key":"17_CR4","doi-asserted-by":"publisher","first-page":"993","DOI":"10.1002\/eji.201546073","volume":"46","author":"H Georgiev","year":"2016","unstructured":"Georgiev H, Ravens I, Shibuya A, F\u00f6rster R, Bernhardt G (2016) CD155\/CD226-interaction impacts on the generation of innate CD8(+) thymocytes by regulating iNKT-cell differentiation. Eur J Immunol 46:993\u20131003","journal-title":"Eur J Immunol"},{"key":"17_CR5","doi-asserted-by":"publisher","first-page":"248","DOI":"10.1038\/laban0810-248","volume":"39","author":"R Blair-Handon","year":"2010","unstructured":"Blair-Handon R, Mueller K, Hoogstraten-Miller S (2010) An alternative method for intrathymic injections in mice. Lab Anim (NY) 39:248\u2013252","journal-title":"Lab Anim (NY)"},{"key":"17_CR6","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.34793","volume":"7","author":"H Wang","year":"2018","unstructured":"Wang H, Hogquist KA (2018) CCR7 defines a precursor for murine iNKT cells in thymus and periphery. elife 7:e34793","journal-title":"elife"},{"key":"17_CR7","doi-asserted-by":"publisher","first-page":"1","DOI":"10.21769\/BioProtoc.3107","volume":"8","author":"H Wang","year":"2018","unstructured":"Wang H, Owen D, Qian LJ, Chopp Laura B (2018) Ultrasound guided intra-thymic injection to track recent thymic emigrants and investigate T cell development. Bio-Protoc 8:1\u20139","journal-title":"Bio-Protoc"},{"key":"17_CR8","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1038\/s41590-018-0289-6","volume":"20","author":"DL Owen","year":"2019","unstructured":"Owen DL, Mahmud SA, Sjaastad LE et al (2019) Thymic regulatory T cells arise via two distinct developmental programs. Nat Immunol 20:195\u2013205","journal-title":"Nat Immunol"},{"key":"17_CR9","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1034\/j.1600-065X.2003.00077.x","volume":"195","author":"J Gill","year":"2003","unstructured":"Gill J, Malin M, Sutherland J, Gray D, Hollander G, Boyd R (2003) Thymic generation and regeneration. Immunol Rev 195:28\u201350","journal-title":"Immunol Rev"}],"container-title":["Methods in Molecular Biology","T-Cell Development"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/978-1-0716-2740-2_17","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,11,14]],"date-time":"2022-11-14T10:48:33Z","timestamp":1668422913000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/978-1-0716-2740-2_17"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11,15]]},"ISBN":["9781071627396","9781071627402"],"references-count":9,"URL":"https:\/\/doi.org\/10.1007\/978-1-0716-2740-2_17","relation":{},"ISSN":["1064-3745","1940-6029"],"issn-type":[{"type":"print","value":"1064-3745"},{"type":"electronic","value":"1940-6029"}],"subject":[],"published":{"date-parts":[[2022,11,15]]},"assertion":[{"value":"15 November 2022","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}}]}}