{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T16:56:16Z","timestamp":1758819376410,"version":"3.40.3"},"publisher-location":"New York, NY","reference-count":22,"publisher":"Springer US","isbn-type":[{"type":"print","value":"9781071627716"},{"type":"electronic","value":"9781071627723"}],"license":[{"start":{"date-parts":[[2022,11,19]],"date-time":"2022-11-19T00:00:00Z","timestamp":1668816000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2022,11,19]],"date-time":"2022-11-19T00:00:00Z","timestamp":1668816000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023]]},"DOI":"10.1007\/978-1-0716-2772-3_10","type":"book-chapter","created":{"date-parts":[[2022,11,18]],"date-time":"2022-11-18T18:07:03Z","timestamp":1668794823000},"page":"165-182","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Use of Glycine to Augment Exon Skipping and Cell Therapies for Duchenne Muscular Dystrophy"],"prefix":"10.1007","author":[{"given":"Gang","family":"Han","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caorui","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"HaiFang","family":"Yin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,11,19]]},"reference":[{"issue":"6","key":"10_CR1","doi-asserted-by":"publisher","first-page":"544","DOI":"10.1161\/CIRCGENETICS.109.867242","volume":"2","author":"RW Kaspar","year":"2009","unstructured":"Kaspar RW, Allen HD, Ray WC et al (2009) Analysis of dystrophin deletion mutations predicts age of cardiomyopathy onset in Becker muscular dystrophy. Circ Cardiovasc Genet 2(6):544\u2013551. https:\/\/doi.org\/10.1161\/CIRCGENETICS.109.867242","journal-title":"Circ Cardiovasc Genet"},{"key":"10_CR2","doi-asserted-by":"publisher","unstructured":"Sheikh O, Yokota T (2021) Restoring protein expression in neuromuscular conditions: a review assessing the current state of exon skipping\/inclusion and gene therapies for Duchenne muscular dystrophy and spinal muscular atrophy. BioDrugs. https:\/\/doi.org\/10.1007\/s40259-021-00486-7","DOI":"10.1007\/s40259-021-00486-7"},{"issue":"5","key":"10_CR3","doi-asserted-by":"publisher","first-page":"637","DOI":"10.1002\/ana.23982","volume":"74","author":"JR Mendell","year":"2013","unstructured":"Mendell JR, Rodino-Klapac LR, Sahenk Z et al (2013) Eteplirsen for the treatment of Duchenne muscular dystrophy. Ann Neurol 74(5):637\u2013647. https:\/\/doi.org\/10.1002\/ana.23982","journal-title":"Ann Neurol"},{"issue":"16","key":"10_CR4","doi-asserted-by":"publisher","first-page":"1513","DOI":"10.1056\/NEJMoa1011367","volume":"364","author":"NM Goemans","year":"2011","unstructured":"Goemans NM, Tulinius M, van den Akker JT et al (2011) Systemic administration of PRO051 in Duchenne\u2019s muscular dystrophy. N Engl J Med 364(16):1513\u20131522. https:\/\/doi.org\/10.1056\/NEJMoa1011367","journal-title":"N Engl J Med"},{"issue":"11","key":"10_CR5","doi-asserted-by":"publisher","first-page":"5652","DOI":"10.1172\/JCI142031","volume":"130","author":"S Biressi","year":"2020","unstructured":"Biressi S, Filareto A, Rando TA (2020) Stem cell therapy for muscular dystrophies. J Clin Invest 130(11):5652\u20135664. https:\/\/doi.org\/10.1172\/JCI142031","journal-title":"J Clin Invest"},{"issue":"1","key":"10_CR6","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1038\/sj.mt.6300329","volume":"16","author":"H Yin","year":"2008","unstructured":"Yin H, Lu Q, Wood M (2008) Effective exon skipping and restoration of dystrophin expression by peptide nucleic acid antisense oligonucleotides in mdx mice. Mol Ther 16(1):38\u201345. https:\/\/doi.org\/10.1038\/sj.mt.6300329","journal-title":"Mol Ther"},{"issue":"22","key":"10_CR7","doi-asserted-by":"publisher","first-page":"4405","DOI":"10.1093\/hmg\/ddp395","volume":"18","author":"H Yin","year":"2009","unstructured":"Yin H, Moulton HM, Betts C et al (2009) A fusion peptide directs enhanced systemic dystrophin exon skipping and functional restoration in dystrophin-deficient mdx mice. Hum Mol Genet 18(22):4405\u20134414. https:\/\/doi.org\/10.1093\/hmg\/ddp395","journal-title":"Hum Mol Genet"},{"issue":"24","key":"10_CR8","doi-asserted-by":"publisher","first-page":"3909","DOI":"10.1093\/hmg\/ddn293","volume":"17","author":"H Yin","year":"2008","unstructured":"Yin H, Moulton HM, Seow Y et al (2008) Cell-penetrating peptide-conjugated antisense oligonucleotides restore systemic muscle and cardiac dystrophin expression and function. Hum Mol Genet 17(24):3909\u20133918. https:\/\/doi.org\/10.1093\/hmg\/ddn293","journal-title":"Hum Mol Genet"},{"issue":"7","key":"10_CR9","doi-asserted-by":"publisher","first-page":"1295","DOI":"10.1038\/mt.2011.79","volume":"19","author":"H Yin","year":"2011","unstructured":"Yin H, Saleh AF, Betts C et al (2011) Pip5 transduction peptides direct high efficiency oligonucleotide-mediated dystrophin exon skipping in heart and phenotypic correction in mdx mice. Mol Ther 19(7):1295\u20131303. https:\/\/doi.org\/10.1038\/mt.2011.79","journal-title":"Mol Ther"},{"issue":"7","key":"10_CR10","doi-asserted-by":"publisher","first-page":"1333","DOI":"10.1038\/mt.2014.63","volume":"22","author":"X Gao","year":"2014","unstructured":"Gao X, Zhao J, Han G et al (2014) Effective dystrophin restoration by a novel muscle-homing peptide-morpholino conjugate in dystrophin-deficient mdx mice. Mol Ther 22(7):1333\u20131341. https:\/\/doi.org\/10.1038\/mt.2014.63","journal-title":"Mol Ther"},{"issue":"39","key":"10_CR11","doi-asserted-by":"publisher","first-page":"10962","DOI":"10.1073\/pnas.1605731113","volume":"113","author":"SM Hammond","year":"2016","unstructured":"Hammond SM, Hazell G, Shabanpoor F et al (2016) Systemic peptide-mediated oligonucleotide therapy improves long-term survival in spinal muscular atrophy. Proc Natl Acad Sci U S A 113(39):10962\u201310967. https:\/\/doi.org\/10.1073\/pnas.1605731113","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"5","key":"10_CR12","doi-asserted-by":"publisher","first-page":"715","DOI":"10.1007\/s00018-009-0186-0","volume":"67","author":"F Said Hassane","year":"2010","unstructured":"Said Hassane F, Saleh AF, Abes R et al (2010) Cell penetrating peptides: overview and applications to the delivery of oligonucleotides. Cell Mol Life Sci 67(5):715\u2013726. https:\/\/doi.org\/10.1007\/s00018-009-0186-0","journal-title":"Cell Mol Life Sci"},{"key":"10_CR13","doi-asserted-by":"publisher","unstructured":"Biswas S (2021) Polymeric micelles as drug delivery systems in cancer: challenges and opportunities. Nanomedicine (London). https:\/\/doi.org\/10.2217\/nnm-2021-0081","DOI":"10.2217\/nnm-2021-0081"},{"issue":"1","key":"10_CR14","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1007\/s40820-020-00561-8","volume":"13","author":"H Yang","year":"2021","unstructured":"Yang H, Liu R, Xu Y et al (2021) Photosensitizer nanoparticles boost photodynamic therapy for pancreatic cancer treatment. Nano-Micro Lett 13(1):35. https:\/\/doi.org\/10.1007\/s40820-020-00561-8","journal-title":"Nano-Micro Lett"},{"issue":"2","key":"10_CR15","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1016\/j.jconrel.2008.10.020","volume":"134","author":"Y Kim","year":"2009","unstructured":"Kim Y, Tewari M, Pajerowski JD et al (2009) Polymersome delivery of siRNA and antisense oligonucleotides. J Control Release 134(2):132\u2013140. https:\/\/doi.org\/10.1016\/j.jconrel.2008.10.020","journal-title":"J Control Release"},{"issue":"5","key":"10_CR16","doi-asserted-by":"publisher","first-page":"820","DOI":"10.1038\/mt.2009.8","volume":"17","author":"P Rimessi","year":"2009","unstructured":"Rimessi P, Sabatelli P, Fabris M et al (2009) Cationic PMMA nanoparticles bind and deliver antisense oligoribonucleotides allowing restoration of dystrophin expression in the mdx mouse. Mol Ther 17(5):820\u2013827. https:\/\/doi.org\/10.1038\/mt.2009.8","journal-title":"Mol Ther"},{"key":"10_CR17","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/1477-3155-7-1","volume":"7","author":"SR Sirsi","year":"2009","unstructured":"Sirsi SR, Schray RC, Wheatley MA et al (2009) Formulation of polylactide-co-glycolic acid nanospheres for encapsulation and sustained release of poly(ethylene imine)-poly(ethylene glycol) copolymers complexed to oligonucleotides. J Nanobiotechnol 7:1. https:\/\/doi.org\/10.1186\/1477-3155-7-1","journal-title":"J Nanobiotechnol"},{"key":"10_CR18","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1186\/1472-6750-8-35","volume":"8","author":"JH Williams","year":"2008","unstructured":"Williams JH, Schray RC, Sirsi SR et al (2008) Nanopolymers improve delivery of exon skipping oligonucleotides and concomitant dystrophin expression in skeletal muscle of mdx mice. BMC Biotechnol 8:35. https:\/\/doi.org\/10.1186\/1472-6750-8-35","journal-title":"BMC Biotechnol"},{"key":"10_CR19","doi-asserted-by":"publisher","unstructured":"Gao X, Ran N, Dong X et al (2018) Anchor peptide captures, targets, and loads exosomes of diverse origins for diagnostics and therapy. Sci Transl Med 10(444). https:\/\/doi.org\/10.1126\/scitranslmed.aat0195","DOI":"10.1126\/scitranslmed.aat0195"},{"key":"10_CR20","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1016\/j.omtn.2019.09.012","volume":"18","author":"G Han","year":"2019","unstructured":"Han G, Gu B, Lin C et al (2019) Hexose potentiates peptide-conjugated Morpholino oligomer efficacy in cardiac muscles of dystrophic mice in an age-dependent manner. Mol Ther Nucl Acids 18:341\u2013350. https:\/\/doi.org\/10.1016\/j.omtn.2019.09.012","journal-title":"Mol Ther Nucl Acids"},{"key":"10_CR21","doi-asserted-by":"publisher","first-page":"10981","DOI":"10.1038\/ncomms10981","volume":"7","author":"G Han","year":"2016","unstructured":"Han G, Gu B, Cao L et al (2016) Hexose enhances oligonucleotide delivery and exon skipping in dystrophin-deficient mdx mice. Nat Commun 7:10981. https:\/\/doi.org\/10.1038\/ncomms10981","journal-title":"Nat Commun"},{"issue":"5","key":"10_CR22","doi-asserted-by":"publisher","first-page":"1339","DOI":"10.1016\/j.ymthe.2020.03.003","volume":"28","author":"C Lin","year":"2020","unstructured":"Lin C, Han G, Ning H et al (2020) Glycine enhances satellite cell proliferation, cell transplantation, and oligonucleotide efficacy in dystrophic muscle. Mol Ther 28(5):1339\u20131358. https:\/\/doi.org\/10.1016\/j.ymthe.2020.03.003","journal-title":"Mol Ther"}],"container-title":["Methods in Molecular Biology","Muscular Dystrophy Therapeutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/978-1-0716-2772-3_10","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T07:07:25Z","timestamp":1677654445000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/978-1-0716-2772-3_10"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11,19]]},"ISBN":["9781071627716","9781071627723"],"references-count":22,"URL":"https:\/\/doi.org\/10.1007\/978-1-0716-2772-3_10","relation":{},"ISSN":["1064-3745","1940-6029"],"issn-type":[{"type":"print","value":"1064-3745"},{"type":"electronic","value":"1940-6029"}],"subject":[],"published":{"date-parts":[[2022,11,19]]},"assertion":[{"value":"19 November 2022","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}}]}}