{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,28]],"date-time":"2025-03-28T06:46:55Z","timestamp":1743144415976,"version":"3.40.3"},"publisher-location":"New York, NY","reference-count":49,"publisher":"Springer US","isbn-type":[{"type":"print","value":"9781071631386"},{"type":"electronic","value":"9781071631393"}],"license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023]]},"DOI":"10.1007\/978-1-0716-3139-3_14","type":"book-chapter","created":{"date-parts":[[2023,5,30]],"date-time":"2023-05-30T13:02:55Z","timestamp":1685451775000},"page":"239-260","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Models and Methods for Evaluating Regeneration of Spermatogenesis After Cytotoxic Treatments"],"prefix":"10.1007","author":[{"given":"Gunapala","family":"Shetty","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2023,5,31]]},"reference":[{"issue":"5","key":"14_CR1","doi-asserted-by":"publisher","first-page":"1180","DOI":"10.1016\/j.fertnstert.2013.08.010","volume":"100","author":"ML Meistrich","year":"2013","unstructured":"Meistrich ML (2013) Effects of chemotherapy and radiotherapy on spermatogenesis in humans. Fertil Steril 100(5):1180\u20131186. https:\/\/doi.org\/10.1016\/j.fertnstert.2013.08.010","journal-title":"Fertil Steril"},{"issue":"3","key":"14_CR2","doi-asserted-by":"publisher","first-page":"545","DOI":"10.1111\/andr.12740","volume":"8","author":"ML Meistrich","year":"2020","unstructured":"Meistrich ML (2020) Risks of genetic damage in offspring conceived using spermatozoa produced during chemotherapy or radiotherapy. Andrology 8(3):545\u2013558. https:\/\/doi.org\/10.1111\/andr.12740","journal-title":"Andrology"},{"key":"14_CR3","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1046\/j.1365-2605.2003.00400.x","volume":"26","author":"ML Meistrich","year":"2003","unstructured":"Meistrich ML, Shetty G (2003) Suppression of testosterone stimulates recovery of spermatogenesis after cancer treatment. Int J Androl 26:141\u2013146","journal-title":"Int J Androl"},{"key":"14_CR4","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1093\/jncimonographs\/lgi002","volume":"34","author":"G Shetty","year":"2005","unstructured":"Shetty G, Meistrich ML (2005) Hormonal approaches to preservation and restoration of male fertility after cancer treatment. J Natl Cancer Inst Monogr 34:36\u201339","journal-title":"J Natl Cancer Inst Monogr"},{"issue":"5","key":"14_CR5","doi-asserted-by":"publisher","first-page":"1735","DOI":"10.1210\/endo.141.5.7446","volume":"141","author":"G Shetty","year":"2000","unstructured":"Shetty G, Wilson G, Huhtaniemi I, Shuttlesworth GA, Reissmann T, Meistrich ML (2000) Gonadotropin-releasing hormone analogs stimulate and testosterone inhibits the recovery of spermatogenesis in irradiated rats. Endocrinology 141(5):1735\u20131745","journal-title":"Endocrinology"},{"key":"14_CR6","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1002\/jcp.20910","volume":"211","author":"Z Zhang","year":"2007","unstructured":"Zhang Z, Shao S, Meistrich ML (2007) The radiation-induced block in spermatogonial differentiation is due to damage to the somatic environment, not the germ cells. J Cell Physiol 211:149\u2013158","journal-title":"J Cell Physiol"},{"key":"14_CR7","doi-asserted-by":"publisher","first-page":"3385","DOI":"10.1210\/en.2002-220206","volume":"143","author":"G Shetty","year":"2002","unstructured":"Shetty G, Wilson G, Hardy MP, Niu E, Huhtaniemi I, Meistrich ML (2002) Inhibition of recovery of spermatogenesis in irradiated rats by different androgens. Endocrinology 143:3385\u20133396","journal-title":"Endocrinology"},{"issue":"4","key":"14_CR8","doi-asserted-by":"publisher","first-page":"440","DOI":"10.2164\/jandrol.108.006635","volume":"30","author":"KL Porter","year":"2009","unstructured":"Porter KL, Shetty G, Shuttlesworth G, Weng CY, Huhtaniemi I, Pakarinen P, Meistrich ML (2009) Estrogen enhances recovery from radiation-induced spermatogonial arrest in rat testes. J Androl 30(4):440\u2013451","journal-title":"J Androl"},{"issue":"3","key":"14_CR9","doi-asserted-by":"publisher","first-page":"412","DOI":"10.1111\/andr.12168","volume":"4","author":"G Shetty","year":"2016","unstructured":"Shetty G, Zhou W, Weng CC, Shao SH, Meistrich ML (2016) Leydig cells contribute to the inhibition of spermatogonial differentiation after irradiation of the rat. Andrology 4(3):412\u2013424. https:\/\/doi.org\/10.1111\/andr.12168","journal-title":"Andrology"},{"issue":"1","key":"14_CR10","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1093\/toxsci\/kfq191","volume":"117","author":"G Wang","year":"2010","unstructured":"Wang G, Shao SH, Weng CC, Wei C, Meistrich ML (2010) Hormonal suppression restores fertility in irradiated mice from both endogenous and donor-derived stem spermatogonia. Toxicol Sci 117(1):225\u2013237","journal-title":"Toxicol Sci"},{"issue":"6","key":"14_CR11","doi-asserted-by":"publisher","first-page":"886","DOI":"10.1111\/j.2047-2927.2013.00126.x","volume":"1","author":"G Shetty","year":"2013","unstructured":"Shetty G, Uthamanthil RK, Zhou W, Shao SH, Weng CC, Tailor RC, Hermann BP, Orwig KE, Meistrich ML (2013) Hormone suppression with GnRH antagonist promotes spermatogenic recovery from transplanted spermatogonial stem cells in irradiated cynomolgus monkeys. Andrology 1(6):886\u2013898. https:\/\/doi.org\/10.1111\/j.2047-2927.2013.00126.x","journal-title":"Andrology"},{"issue":"6","key":"14_CR12","doi-asserted-by":"publisher","first-page":"1579","DOI":"10.1095\/biolreprod66.6.1579","volume":"66","author":"LB Creemers","year":"2002","unstructured":"Creemers LB, Meng X, den Ouden K, van Pelt AM, Izadyar F, Santoro M, Sariola H, de Rooij DG (2002) Transplantation of germ cells from glial cell line-derived neurotrophic factor-overexpressing mice to host testes depleted of endogenous spermatogenesis by fractionated irradiation. Biol Reprod 66(6):1579\u20131584","journal-title":"Biol Reprod"},{"key":"14_CR13","doi-asserted-by":"publisher","first-page":"349","DOI":"10.2307\/3574894","volume":"74","author":"ML Meistrich","year":"1978","unstructured":"Meistrich ML, Hunter N, Suzuki N, Trostle PK, Withers HR (1978) Gradual regeneration of mouse testicular stem cells after ionizing radiation. Radiat Res 74:349\u2013362","journal-title":"Radiat Res"},{"issue":"2","key":"14_CR14","doi-asserted-by":"publisher","first-page":"206","DOI":"10.1111\/j.2047-2927.2012.00034.x","volume":"1","author":"M Abuelhija","year":"2013","unstructured":"Abuelhija M, Weng CC, Shetty G, Meistrich ML (2013) Rat models of post-irradiation recovery of spermatogenesis: interstrain differences. Andrology 1(2):206\u2013215. https:\/\/doi.org\/10.1111\/j.2047-2927.2012.00034.x","journal-title":"Andrology"},{"key":"14_CR15","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1016\/0027-5107(87)90057-1","volume":"176","author":"LR Bucci","year":"1987","unstructured":"Bucci LR, Meistrich ML (1987) Effects of busulfan on murine spermatogenesis: cytotoxicity, sterility, sperm abnormalities, and dominant lethal mutations. Mutat Res 176:259\u2013268","journal-title":"Mutat Res"},{"issue":"3","key":"14_CR16","doi-asserted-by":"publisher","first-page":"365","DOI":"10.2164\/jandrol.05179","volume":"27","author":"Z Zhang","year":"2006","unstructured":"Zhang Z, Shao S, Meistrich ML (2006) Irradiated mouse testes efficiently support spermatogenesis derived from donor germ cells of mice and rats. J Androl 27(3):365\u2013375","journal-title":"J Androl"},{"issue":"7","key":"14_CR17","doi-asserted-by":"publisher","first-page":"8423","DOI":"10.1096\/fj.201802361R","volume":"33","author":"PA Parekh","year":"2019","unstructured":"Parekh PA, Garcia TX, Waheeb R, Jain V, Gandhi P, Meistrich ML, Shetty G, Hofmann MC (2019) Undifferentiated spermatogonia regulate Cyp26b1 expression through NOTCH signaling and drive germ cell differentiation. FASEB J 33(7):8423\u20138435. https:\/\/doi.org\/10.1096\/fj.201802361R","journal-title":"FASEB J"},{"issue":"4","key":"14_CR18","doi-asserted-by":"publisher","first-page":"395","DOI":"10.1016\/j.reprotox.2011.09.010","volume":"32","author":"AL Drumond","year":"2011","unstructured":"Drumond AL, Weng CC, Wang G, Chiarini-Garcia H, Eras-Garcia L, Meistrich ML (2011) Effects of multiple doses of cyclophosphamide on mouse testes: accessing the germ cells lost, and the functional damage of stem cells. Reprod Toxicol 32(4):395\u2013406. https:\/\/doi.org\/10.1016\/j.reprotox.2011.09.010. S0890-6238(11)00381-9 [pii]","journal-title":"Reprod Toxicol"},{"key":"14_CR19","first-page":"3575","volume":"39","author":"CC Lu","year":"1979","unstructured":"Lu CC, Meistrich ML (1979) Cytotoxic effects of chemotherapeutic drugs on mouse testis cells. Cancer Res 39:3575\u20133582","journal-title":"Cancer Res"},{"issue":"2","key":"14_CR20","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1046\/j.1365-2613.1998.00057.x","volume":"79","author":"DG de Rooij","year":"1998","unstructured":"de Rooij DG (1998) Stem cells in the testis. Int J Exp Pathol 79(2):67\u201380","journal-title":"Int J Exp Pathol"},{"issue":"9","key":"14_CR21","doi-asserted-by":"publisher","first-page":"2330","DOI":"10.1634\/stemcells.2007-0143","volume":"25","author":"BP Hermann","year":"2007","unstructured":"Hermann BP, Sukhwani M, Lin CC, Sheng Y, Tomko J, Rodriguez M, Shuttleworth JJ, McFarland D, Hobbs RM, Pandolfi PP, Schatten GP, Orwig KE (2007) Characterization, cryopreservation, and ablation of spermatogonial stem cells in adult rhesus macaques. Stem Cells 25(9):2330\u20132338","journal-title":"Stem Cells"},{"issue":"5","key":"14_CR22","doi-asserted-by":"publisher","first-page":"715","DOI":"10.1016\/j.stem.2012.07.017","volume":"11","author":"BP Hermann","year":"2012","unstructured":"Hermann BP, Sukhwani M, Winkler F, Pascarella JN, Peters KA, Sheng Y, Valli H, Rodriguez M, Ezzelarab M, Dargo G, Peterson K, Masterson K, Ramsey C, Ward T, Lienesch M, Volk A, Cooper DK, Thomson AW, Kiss JE, Penedo MC, Schatten GP, Mitalipov S, Orwig KE (2012) Spermatogonial stem cell transplantation into rhesus testes regenerates spermatogenesis producing functional sperm. Cell Stem Cell 11(5):715\u2013726. https:\/\/doi.org\/10.1016\/j.stem.2012.07.017. S1934-5909(12)00475-4 [pii]","journal-title":"Cell Stem Cell"},{"issue":"5","key":"14_CR23","doi-asserted-by":"publisher","first-page":"1273","DOI":"10.1182\/blood-2003-08-2935","volume":"104","author":"K Kuramoto","year":"2004","unstructured":"Kuramoto K, Follman D, Hematti P, Sellers S, Laukkanen MO, Seggewiss R, Metzger ME, Krouse A, Donahue RE, von Kalle C, Dunbar CE (2004) The impact of low-dose busulfan on clonal dynamics in nonhuman primates. Blood 104(5):1273\u20131280. https:\/\/doi.org\/10.1182\/blood-2003-08-2935","journal-title":"Blood"},{"issue":"2","key":"14_CR24","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1016\/j.exphem.2005.10.010","volume":"34","author":"EM Kang","year":"2006","unstructured":"Kang EM, Hsieh MM, Metzger M, Krouse A, Donahue RE, Sadelain M, Tisdale JF (2006) Busulfan pharmacokinetics, toxicity, and low-dose conditioning for autologous transplantation of genetically modified hematopoietic stem cells in the rhesus macaque model. Exp Hematol 34(2):132\u2013139. https:\/\/doi.org\/10.1016\/j.exphem.2005.10.010","journal-title":"Exp Hematol"},{"issue":"6","key":"14_CR25","doi-asserted-by":"publisher","first-page":"695","DOI":"10.1089\/hum.2009.191","volume":"21","author":"J Xie","year":"2010","unstructured":"Xie J, Larochelle A, Maric I, Faulhaber M, Donahue RE, Dunbar CE (2010) Repetitive busulfan administration after hematopoietic stem cell gene therapy associated with a dominant HDAC7 clone in a nonhuman primate. Hum Gene Ther 21(6):695\u2013703. https:\/\/doi.org\/10.1089\/hum.2009.191","journal-title":"Hum Gene Ther"},{"issue":"9","key":"14_CR26","doi-asserted-by":"publisher","first-page":"1586","DOI":"10.1016\/j.ymthe.2019.05.022","volume":"27","author":"N Uchida","year":"2019","unstructured":"Uchida N, Nassehi T, Drysdale CM, Gamer J, Yapundich M, Bonifacino AC, Krouse AE, Linde N, Hsieh MM, Donahue RE, Dunbar CE, Kean LS, Tisdale JF (2019) Busulfan combined with immunosuppression allows efficient engraftment of gene-modified cells in a rhesus macaque model. Mol Ther 27(9):1586\u20131596. https:\/\/doi.org\/10.1016\/j.ymthe.2019.05.022","journal-title":"Mol Ther"},{"issue":"11","key":"14_CR27","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0206980","volume":"13","author":"N Mahmud","year":"2018","unstructured":"Mahmud N, Khanal A, Taioli S, Koca E, Gaitonde S, Petro B, Sweiss K, Halliday L, Wang X, Patel P, Rondelli D (2018) Preclinical IV busulfan dose-finding study to induce reversible myeloablation in a non-human primate model. PLoS One 13(11):e0206980. https:\/\/doi.org\/10.1371\/journal.pone.0206980","journal-title":"PLoS One"},{"key":"14_CR28","volume-title":"Current protocols in immunology","author":"RE Donahue","year":"2005","unstructured":"Donahue RE, Kuramoto K, Dunbar CE (2005) Sources and methods to obtain stem and progenitor cells. In: Current protocols in immunology, vol Unit 22A.1. Wiley, Hoboken"},{"issue":"5974","key":"14_CR29","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1126\/science.1182868","volume":"328","author":"T Nakagawa","year":"2010","unstructured":"Nakagawa T, Sharma M, Nabeshima Y, Braun RE, Yoshida S (2010) Functional hierarchy and reversibility within the murine spermatogenic stem cell compartment. Science 328(5974):62\u201367. https:\/\/doi.org\/10.1126\/science.1182868","journal-title":"Science"},{"issue":"1","key":"14_CR30","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1210\/endo.141.1.7272","volume":"141","author":"GA Shuttlesworth","year":"2000","unstructured":"Shuttlesworth GA, de Rooij DG, Huhtaniemi I, Reissmann T, Russell LD, Shetty G, Wilson G, Meistrich ML (2000) Enhancement of a spermatogonial proliferation and differentiation in irradiated rats by GnRH antagonist administration. Endocrinology 141(1):37\u201349","journal-title":"Endocrinology"},{"issue":"1","key":"14_CR31","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1016\/j.stem.2018.11.013","volume":"24","author":"Y Kitadate","year":"2019","unstructured":"Kitadate Y, Jorg DJ, Tokue M, Maruyama A, Ichikawa R, Tsuchiya S, Segi-Nishida E, Nakagawa T, Uchida A, Kimura-Yoshida C, Mizuno S, Sugiyama F, Azami T, Ema M, Noda C, Kobayashi S, Matsuo I, Kanai Y, Nagasawa T, Sugimoto Y, Takahashi S, Simons BD, Yoshida S (2019) Competition for mitogens regulates spermatogenic stem cell homeostasis in an open niche. Cell Stem Cell 24(1):79\u201392. e76. https:\/\/doi.org\/10.1016\/j.stem.2018.11.013","journal-title":"Cell Stem Cell"},{"key":"14_CR32","doi-asserted-by":"publisher","first-page":"88","DOI":"10.2307\/3573759","volume":"57","author":"HR Withers","year":"1974","unstructured":"Withers HR, Hunter N, Barkley HT, Reid BO (1974) Radiation survival and regeneration characteristics of spermatogenic stem cell of mouse testis. Radiat Res 57:88\u2013103","journal-title":"Radiat Res"},{"issue":"9","key":"14_CR33","doi-asserted-by":"publisher","first-page":"3504","DOI":"10.1210\/en.2011-0251","volume":"152","author":"G Shetty","year":"2011","unstructured":"Shetty G, Porter KL, Zhou W, Shao SH, Weng CC, Meistrich ML (2011) Androgen suppression-induced stimulation of spermatogonial differentiation in juvenile spermatogonial depletion mice acts by elevating the testicular temperature. Endocrinology 152(9):3504\u20133514. https:\/\/doi.org\/10.1210\/en.2011-0251. en.2011-0251 [pii]","journal-title":"Endocrinology"},{"issue":"3","key":"14_CR34","doi-asserted-by":"publisher","first-page":"1297","DOI":"10.1210\/en.2005-0890","volume":"147","author":"KL Porter","year":"2006","unstructured":"Porter KL, Shetty G, Meistrich ML (2006) Testicular edema is associated with spermatogonial arrest in irradiated rats. Endocrinology 147(3):1297\u20131305","journal-title":"Endocrinology"},{"key":"14_CR35","doi-asserted-by":"publisher","first-page":"478","DOI":"10.2307\/3576138","volume":"97","author":"ML Meistrich","year":"1984","unstructured":"Meistrich ML, Finch M, Lu CC, De Ruiter-Bootsma AL, de Rooij DG, Davids JAG (1984) Strain differences in the response of mouse testicular stem cells to fractionated radiation. Radiat Res 97:478\u2013487","journal-title":"Radiat Res"},{"issue":"2","key":"14_CR36","doi-asserted-by":"publisher","first-page":"545","DOI":"10.1093\/toxsci\/kfs021","volume":"126","author":"M Abuelhija","year":"2012","unstructured":"Abuelhija M, Weng CC, Shetty G, Meistrich ML (2012) Differences in radiation sensitivity of recovery of spermatogenesis between rat strains. Toxicol Sci 126(2):545\u2013553. https:\/\/doi.org\/10.1093\/toxsci\/kfs021. kfs021 [pii]","journal-title":"Toxicol Sci"},{"key":"14_CR37","doi-asserted-by":"publisher","first-page":"1200","DOI":"10.1095\/biolreprod54.6.1200","volume":"54","author":"M Kangasniemi","year":"1996","unstructured":"Kangasniemi M, Huhtaniemi I, Meistrich ML (1996) Failure of spermatogenesis to recover despite the presence of a spermatogonia in the irradiated LBNF1 rat. Biol Reprod 54:1200\u20131208","journal-title":"Biol Reprod"},{"issue":"8","key":"14_CR38","doi-asserted-by":"publisher","first-page":"1945","DOI":"10.1093\/humrep\/der160","volume":"26","author":"K Jahnukainen","year":"2011","unstructured":"Jahnukainen K, Ehmcke J, Quader MA, Saiful Huq M, Epperly MW, Hergenrother S, Nurmio M, Schlatt S (2011) Testicular recovery after irradiation differs in prepubertal and pubertal non-human primates, and can be enhanced by autologous germ cell transplantation. Hum Reprod 26(8):1945\u20131954. https:\/\/doi.org\/10.1093\/humrep\/der160. der160 [pii]","journal-title":"Hum Reprod"},{"issue":"1","key":"14_CR39","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1093\/humrep\/17.1.55","volume":"17","author":"S Schlatt","year":"2002","unstructured":"Schlatt S, Foppiani L, Rolf C, Weinbauer GF, Nieschlag E (2002) Germ cell transplantation into X-irradiated monkey testes. Hum Reprod 17(1):55\u201362","journal-title":"Hum Reprod"},{"issue":"2","key":"14_CR40","doi-asserted-by":"publisher","first-page":"222","DOI":"10.1002\/j.1939-4640.2005.tb01089.x","volume":"26","author":"K Boekelheide","year":"2005","unstructured":"Boekelheide K, Schoenfeld H, Hall SJ, Weng CCY, Shetty G, Leith J, Harper J, Sigman M, Hess DL, Meistrich ML (2005) Gonadotropin-releasing hormone antagonist (cetrorelix) therapy fails to protect non-human primates (macaca arctoides) from radiation-induced spermatogenic failure. J Androl 26(2):222\u2013234","journal-title":"J Androl"},{"key":"14_CR41","doi-asserted-by":"publisher","first-page":"423","DOI":"10.1002\/jemt.1070320505","volume":"32","author":"NG Wreford","year":"1995","unstructured":"Wreford NG (1995) Theory and practice of stereological techniques applied to the estimation of cell number and nuclear volume in the testis. Microsc Res Tech 32:423\u2013436","journal-title":"Microsc Res Tech"},{"issue":"1","key":"14_CR42","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1016\/j.aanat.2012.07.008","volume":"196","author":"A Noorafshan","year":"2014","unstructured":"Noorafshan A (2014) Stereology as a valuable tool in the toolbox of testicular research. Ann Anat 196(1):57\u201366. https:\/\/doi.org\/10.1016\/j.aanat.2012.07.008","journal-title":"Ann Anat"},{"issue":"8","key":"14_CR43","doi-asserted-by":"publisher","first-page":"3677","DOI":"10.1210\/endo.136.8.7628410","volume":"136","author":"M Kangasniemi","year":"1995","unstructured":"Kangasniemi M, Wilson G, Huhtaniemi I, Meistrich ML (1995) Protection against procarbazine-induced testicular damage by GnRH-agonist and antiandrogen treatment in the rat. Endocrinology 136(8):3677\u20133680","journal-title":"Endocrinology"},{"issue":"5","key":"14_CR44","doi-asserted-by":"publisher","first-page":"583","DOI":"10.1016\/S0040-8166(98)80039-6","volume":"30","author":"T Ogawa","year":"1998","unstructured":"Ogawa T, Dobrinski I, Avarbock MR, Brinster RL (1998) Leuprolide, a gonadotropin-releasing hormone agonist, enhances colonization after spermatogonial transplantation into mouse testes. Tissue Cell 30(5):583\u2013588","journal-title":"Tissue Cell"},{"key":"14_CR45","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1111\/andr.12571","volume":"7","author":"G Shetty","year":"2018","unstructured":"Shetty G, Wu Z, Lam TNA, Phan TT, Orwig KE, Meistrich ML (2018) Effect of hormone modulations on donor-derived spermatogenesis or colonization after syngeneic and xenotransplantation in mice. Andrology 7:257. https:\/\/doi.org\/10.1111\/andr.12571","journal-title":"Andrology"},{"issue":"5","key":"14_CR46","doi-asserted-by":"publisher","first-page":"1428","DOI":"10.1111\/andr.12807","volume":"8","author":"G Shetty","year":"2020","unstructured":"Shetty G, Mitchell JM, Meyer JM, Wu Z, Lam TNA, Phan TT, Zhang J, Hill L, Tailor RC, Peters KA, Penedo MC, Hanna C, Orwig KE, Meistrich ML (2020) Restoration of functional sperm production in irradiated pubertal rhesus monkeys by spermatogonial stem cell transplantation. Andrology 8(5):1428\u20131441. https:\/\/doi.org\/10.1111\/andr.12807","journal-title":"Andrology"},{"issue":"3","key":"14_CR47","doi-asserted-by":"publisher","first-page":"400","DOI":"10.1007\/BF00455597","volume":"92","author":"DG de Rooij","year":"1968","unstructured":"de Rooij DG, Kramer MF (1968) Spermatogonial stem cell renewal in the rat, mouse and golden hamster. A study with the alkylating agent myleran. Z Zellforsch Mikrosk Anat 92(3):400\u2013405","journal-title":"Z Zellforsch Mikrosk Anat"},{"issue":"4","key":"14_CR48","first-page":"276","volume":"4","author":"MF Kramer","year":"1970","unstructured":"Kramer MF, de Rooij DG (1970) The effect of three alkylating agents on the seminiferous epithelium of rodents. II Cytotoxic effect. Virchows Arch B Cell Pathol 4(4):276\u2013282","journal-title":"Virchows Arch B Cell Pathol"},{"issue":"5","key":"14_CR49","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1016\/j.stem.2008.08.002","volume":"3","author":"M Kanatsu-Shinohara","year":"2008","unstructured":"Kanatsu-Shinohara M, Takehashi M, Takashima S, Lee J, Morimoto H, Chuma S, Raducanu A, Nakatsuji N, Fassler R, Shinohara T (2008) Homing of mouse spermatogonial stem cells to germline niche depends on beta1-integrin. Cell Stem Cell 3(5):533\u2013542","journal-title":"Cell Stem Cell"}],"container-title":["Methods in Molecular Biology","Spermatogonial Stem Cells"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/978-1-0716-3139-3_14","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,30]],"date-time":"2023-05-30T13:04:06Z","timestamp":1685451846000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/978-1-0716-3139-3_14"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023]]},"ISBN":["9781071631386","9781071631393"],"references-count":49,"URL":"https:\/\/doi.org\/10.1007\/978-1-0716-3139-3_14","relation":{},"ISSN":["1064-3745","1940-6029"],"issn-type":[{"type":"print","value":"1064-3745"},{"type":"electronic","value":"1940-6029"}],"subject":[],"published":{"date-parts":[[2023]]},"assertion":[{"value":"31 May 2023","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}}]}}