{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,27]],"date-time":"2025-03-27T05:47:57Z","timestamp":1743054477898,"version":"3.40.3"},"publisher-location":"New York, NY","reference-count":22,"publisher":"Springer US","isbn-type":[{"type":"print","value":"9781071631782"},{"type":"electronic","value":"9781071631799"}],"license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023]]},"DOI":"10.1007\/978-1-0716-3179-9_10","type":"book-chapter","created":{"date-parts":[[2023,7,10]],"date-time":"2023-07-10T03:09:03Z","timestamp":1688958543000},"page":"135-144","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Culture of Three-Dimensional Madin\u2013Darby Canine Kidney (MDCK) Cysts for In Vitro Drug Testing in Polycystic Kidney Disease"],"prefix":"10.1007","author":[{"given":"Sayanthooran","family":"Saravanabavan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gopala K.","family":"Rangan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2023,7,11]]},"reference":[{"issue":"3","key":"10_CR1","doi-asserted-by":"publisher","first-page":"340","DOI":"10.1097\/00041552-199405000-00017","volume":"3","author":"JP Calvet","year":"1994","unstructured":"Calvet JP (1994) Injury and development in polycystic kidney disease. Curr Opin Nephrol Hypertens 3(3):340\u2013348","journal-title":"Curr Opin Nephrol Hypertens"},{"issue":"15","key":"10_CR2","doi-asserted-by":"publisher","first-page":"6007","DOI":"10.1073\/pnas.86.15.6007","volume":"86","author":"R Mangoo-Karim","year":"1989","unstructured":"Mangoo-Karim R, Uchic M, Lechene C, Grantham JJ (1989) Renal epithelial cyst formation and enlargement in vitro: dependence on cAMP. Proc Natl Acad Sci U S A 86(15):6007\u20136011","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"7","key":"10_CR3","doi-asserted-by":"publisher","first-page":"1300","DOI":"10.1681\/ASN.2007070828","volume":"19","author":"B Yang","year":"2008","unstructured":"Yang B, Sonawane ND, Zhao D, Somlo S, Verkman AS (2008) Small-molecule CFTR inhibitors slow cyst growth in polycystic kidney disease. J Am Soc Nephrol 19(7):1300\u20131310","journal-title":"J Am Soc Nephrol"},{"issue":"Suppl 2","key":"10_CR4","first-page":"S109","volume":"2","author":"O Ibraghimov-Beskrovnaya","year":"2006","unstructured":"Ibraghimov-Beskrovnaya O, Bukanov NO (2006) In vitro cystogenesis: the search for drugs antagonizing cyst development. Nephrol Ther 2(Suppl 2):S109\u2013S114","journal-title":"Nephrol Ther"},{"issue":"1","key":"10_CR5","doi-asserted-by":"publisher","first-page":"38","DOI":"10.3390\/antiox11010038","volume":"11","author":"Z Qiu","year":"2021","unstructured":"Qiu Z, He J, Shao G, Hu J, Li X, Zhou H, Li M, Yang B (2021) Obacunone retards renal cyst development in autosomal dominant polycystic kidney disease by activating NRF2. Antioxidants (Basel) 11(1):38","journal-title":"Antioxidants (Basel)"},{"issue":"3","key":"10_CR6","doi-asserted-by":"publisher","first-page":"931","DOI":"10.3181\/00379727-122-31293","volume":"122","author":"CR Gaush","year":"1966","unstructured":"Gaush CR, Hard WL, Smith TF (1966) Characterization of an established line of canine kidney cells (MDCK). Proc Soc Exp Biol Med 122(3):931\u2013935","journal-title":"Proc Soc Exp Biol Med"},{"issue":"6","key":"10_CR7","doi-asserted-by":"publisher","first-page":"1379","DOI":"10.1038\/ki.1989.137","volume":"35","author":"JJ Grantham","year":"1989","unstructured":"Grantham JJ, Uchic M, Cragoe EJ Jr, Kornhaus J, Grantham JA, Donoso V, Mangoo-Karim R, Evan A, McAteer J (1989) Chemical modification of cell proliferation and fluid secretion in renal cysts. Kidney Int 35(6):1379\u20131389","journal-title":"Kidney Int"},{"key":"10_CR8","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1186\/1471-2121-12-43","volume":"12","author":"JD Dukes","year":"2011","unstructured":"Dukes JD, Whitley P, Chalmers AD (2011) The MDCK variety pack: choosing the right strain. BMC Cell Biol 12:43","journal-title":"BMC Cell Biol"},{"issue":"4","key":"10_CR9","doi-asserted-by":"publisher","first-page":"1327","DOI":"10.1038\/ki.1996.445","volume":"50","author":"DP Wallace","year":"1996","unstructured":"Wallace DP, Grantham JJ, Sullivan LP (1996) Chloride and fluid secretion by cultured human polycystic kidney cells. Kidney Int 50(4):1327\u20131336","journal-title":"Kidney Int"},{"issue":"5","key":"10_CR10","doi-asserted-by":"publisher","first-page":"1222","DOI":"10.1038\/ki.1992.184","volume":"41","author":"TK Neufeld","year":"1992","unstructured":"Neufeld TK, Douglass D, Grant M, Ye M, Silva F, Nadasdy T, Grantham JJ (1992) In vitro formation and expansion of cysts derived from human renal cortex epithelial cells. Kidney Int 41(5):1222\u20131236","journal-title":"Kidney Int"},{"issue":"2","key":"10_CR11","doi-asserted-by":"publisher","first-page":"495","DOI":"10.1007\/s00441-007-0521-4","volume":"331","author":"G Elberg","year":"2008","unstructured":"Elberg G, Guruswamy S, Logan CJ, Chen L, Turman MA (2008) Plasticity of epithelial cells derived from human normal and ADPKD kidneys in primary cultures. Cell Tissue Res 331(2):495\u2013508","journal-title":"Cell Tissue Res"},{"issue":"1","key":"10_CR12","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1039\/C7FO01253E","volume":"9","author":"Y Zhu","year":"2018","unstructured":"Zhu Y, Teng T, Wang H, Guo H, Du L, Yang B, Yin X, Sun Y (2018) Quercetin inhibits renal cyst growth in vitro and via parenteral injection in a polycystic kidney disease mouse model. Food Funct 9(1):389\u2013396","journal-title":"Food Funct"},{"issue":"2","key":"10_CR13","doi-asserted-by":"publisher","first-page":"404","DOI":"10.1016\/j.kint.2020.02.012","volume":"98","author":"M Lannoy","year":"2020","unstructured":"Lannoy M, Valluru MK, Chang L, Abdela-Ali F, Peters DJM, Streets AJ, Ong ACM (2020) The positive effect of selective prostaglandin E2 receptor EP2 and EP4 blockade on cystogenesis in vitro is counteracted by increased kidney inflammation in vivo. Kidney Int 98(2):404\u2013419","journal-title":"Kidney Int"},{"issue":"19","key":"10_CR14","doi-asserted-by":"publisher","first-page":"10512","DOI":"10.3390\/ijms221910512","volume":"22","author":"AN Chandra","year":"2021","unstructured":"Chandra AN, Saravanabavan S, Rangan GK (2021) Role of DNA-dependent protein kinase in mediating cyst growth in autosomal dominant polycystic kidney disease. Int J Mol Sci 22(19):10512","journal-title":"Int J Mol Sci"},{"issue":"3","key":"10_CR15","doi-asserted-by":"publisher","first-page":"195","DOI":"10.3892\/mmr.2021.11834","volume":"23","author":"Y Li","year":"2021","unstructured":"Li Y, Gao J, Yang X, Li T, Yang B, Aili A (2021) Combination of curcumin and ginkgolide B inhibits cystogenesis by regulating multiple signaling pathways. Mol Med Rep 23(3):195","journal-title":"Mol Med Rep"},{"issue":"4","key":"10_CR16","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0248400","volume":"16","author":"JQJ Zhang","year":"2021","unstructured":"Zhang JQJ, Saravanabavan S, Cheng KM, Raghubanshi A, Chandra AN, Munt A, Rayner B, Zhang Y, Chau K, Wong ATY, Rangan GK (2021) Long-term dietary nitrate supplementation does not reduce renal cyst growth in experimental autosomal dominant polycystic kidney disease. PLoS One 16(4):e0248400","journal-title":"PLoS One"},{"issue":"3","key":"10_CR17","doi-asserted-by":"publisher","first-page":"532","DOI":"10.3390\/cells10030532","volume":"10","author":"JQJ Zhang","year":"2021","unstructured":"Zhang JQJ, Saravanabavan S, Rangan GK (2021) Effect of reducing ataxia-telangiectasia mutated (ATM) in experimental autosomal dominant polycystic kidney disease. Cell 10(3):532","journal-title":"Cell"},{"issue":"1","key":"10_CR18","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1016\/j.kint.2016.01.026","volume":"90","author":"L Cebotaru","year":"2016","unstructured":"Cebotaru L, Liu Q, Yanda MK, Boinot C, Outeda P, Huso DL, Watnick T, Guggino WB, Cebotaru V (2016) Inhibition of histone deacetylase 6 activity reduces cyst growth in polycystic kidney disease. Kidney Int 90(1):90\u201399","journal-title":"Kidney Int"},{"issue":"3","key":"10_CR19","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1007\/BF01540656","volume":"16","author":"MC Kibbey","year":"1994","unstructured":"Kibbey MC (1994) Maintenance of the EHS sarcoma and Matrigel preparation. J Tissue Cult Methods 16(3):227\u2013230","journal-title":"J Tissue Cult Methods"},{"issue":"7","key":"10_CR20","doi-asserted-by":"publisher","first-page":"507","DOI":"10.1016\/j.cub.2008.02.076","volume":"18","author":"F Martin-Belmonte","year":"2008","unstructured":"Martin-Belmonte F, Yu W, Rodriguez-Fraticelli AE, Ewald AJ, Werb Z, Alonso MA, Mostov K (2008) Cell-polarity dynamics controls the mechanism of lumen formation in epithelial morphogenesis. Curr Biol 18(7):507\u2013513","journal-title":"Curr Biol"},{"issue":"7","key":"10_CR21","doi-asserted-by":"publisher","first-page":"671","DOI":"10.1038\/nmeth.2089","volume":"9","author":"CA Schneider","year":"2012","unstructured":"Schneider CA, Rasband WS, Eliceiri KW (2012) NIH Image to ImageJ: 25 years of image analysis. Nat Methods 9(7):671\u2013675","journal-title":"Nat Methods"},{"issue":"4","key":"10_CR22","doi-asserted-by":"publisher","first-page":"488","DOI":"10.1038\/nm.3092","volume":"19","author":"I Rowe","year":"2013","unstructured":"Rowe I, Chiaravalli M, Mannella V, Ulisse V, Quilici G, Pema M, Song XW, Xu H, Mari S, Qian F, Pei Y, Musco G, Boletta A (2013) Defective glucose metabolism in polycystic kidney disease identifies a new therapeutic strategy. Nat Med 19(4):488\u2013493","journal-title":"Nat Med"}],"container-title":["Methods in Molecular Biology","Kidney Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/978-1-0716-3179-9_10","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,10]],"date-time":"2023-07-10T03:09:28Z","timestamp":1688958568000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/978-1-0716-3179-9_10"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023]]},"ISBN":["9781071631782","9781071631799"],"references-count":22,"URL":"https:\/\/doi.org\/10.1007\/978-1-0716-3179-9_10","relation":{},"ISSN":["1064-3745","1940-6029"],"issn-type":[{"type":"print","value":"1064-3745"},{"type":"electronic","value":"1940-6029"}],"subject":[],"published":{"date-parts":[[2023]]},"assertion":[{"value":"11 July 2023","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}}]}}