{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T00:08:45Z","timestamp":1790208525574,"version":"4.1.0"},"publisher-location":"New York, NY","reference-count":21,"publisher":"Springer US","isbn-type":[{"value":"9781071631980","type":"print"},{"value":"9781071631997","type":"electronic"}],"license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023]]},"DOI":"10.1007\/978-1-0716-3199-7_4","type":"book-chapter","created":{"date-parts":[[2023,5,5]],"date-time":"2023-05-05T12:02:18Z","timestamp":1683288138000},"page":"47-69","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Zebrafish Larvae as an Experimental Model of Cryptococcal Meningitis"],"prefix":"10.1007","author":[{"given":"Z. P.","family":"Chalakova","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. A.","family":"Johnston","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,5,6]]},"reference":[{"key":"4_CR1","doi-asserted-by":"publisher","first-page":"873","DOI":"10.1016\/S1473-3099(17)30243-8","volume":"17","author":"R Rajasingham","year":"2017","unstructured":"Rajasingham R, Smith RM, Park BJ et al (2017) Global burden of disease of HIV-associated cryptococcal meningitis: an updated analysis. Lancet Infect Dis 17:873\u2013881","journal-title":"Lancet Infect Dis"},{"key":"4_CR2","doi-asserted-by":"publisher","first-page":"839","DOI":"10.1016\/S0046-8177(96)90459-1","volume":"27","author":"SC Lee","year":"1996","unstructured":"Lee SC, Dickson DW, Casadevall A et al (1996) Pathology of cryptococcal meningoencephalitis: analysis of 27 patients with pathogenetic implications. Hum Pathol 27:839\u2013847","journal-title":"Hum Pathol"},{"key":"4_CR3","doi-asserted-by":"publisher","first-page":"736","DOI":"10.1093\/cid\/cit794","volume":"58","author":"JN Jarvis","year":"2014","unstructured":"Jarvis JN, Bicanic T, Loyse A et al (2014) Determinants of mortality in a combined cohort of 501 patients with HIV-associated Cryptococcal meningitis: implications for improving outcomes. Clin Infect Dis 58:736\u2013745","journal-title":"Clin Infect Dis"},{"key":"4_CR4","doi-asserted-by":"publisher","first-page":"306","DOI":"10.1002\/cmr.a.21249","volume":"40A","author":"E Van Reeth","year":"2012","unstructured":"Van Reeth E, Tham IWK, Tan CH et al (2012) Super-resolution in magnetic resonance imaging: a review. Concepts Magn Reson 40A:306\u2013325","journal-title":"Concepts Magn Reson"},{"key":"4_CR5","doi-asserted-by":"crossref","unstructured":"Mukaremera L, McDonald TR, Nielsen JN et al (2019) The mouse inhalation model of Cryptococcus neoformans infection recapitulates strain virulence in humans and shows that closely related strains can possess differential virulence. Infect Immun 87(5)","DOI":"10.1128\/IAI.00046-19"},{"issue":"5","key":"4_CR6","doi-asserted-by":"publisher","first-page":"e01425","DOI":"10.1128\/mBio.01425-15","volume":"6","author":"JL Tenor","year":"2015","unstructured":"Tenor JL, Oehlers SH, Yang JL et al (2015) Live imaging of host-parasite interactions in a zebrafish infection model reveals Cryptococcal determinants of virulence and central nervous system invasion. MBio 6(5):e01425\u2013e01415","journal-title":"MBio"},{"issue":"10","key":"4_CR7","doi-asserted-by":"publisher","first-page":"3047","DOI":"10.1128\/IAI.00506-16","volume":"84","author":"JM Davis","year":"2016","unstructured":"Davis JM, Huang M, Botts MR et al (2016) A zebrafish model of Cryptococcal infection reveals roles for macrophages, endothelial cells, and neutrophils in the establishment and control of sustained Fungemia. Infect Immun 84(10):3047\u20133062","journal-title":"Infect Immun"},{"issue":"6","key":"4_CR8","doi-asserted-by":"publisher","first-page":"21489","DOI":"10.1038\/srep21489","volume":"18","author":"A Bojarczuk","year":"2016","unstructured":"Bojarczuk A, Miller KA, Hotham R et al (2016) Cryptococcus neoformans intracellular proliferation and capsule size determines early macrophage control of infection. Sci Rep 18(6):21489","journal-title":"Sci Rep"},{"issue":"3","key":"4_CR9","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1007597","volume":"15","author":"RJ Evans","year":"2019","unstructured":"Evans RJ, Pline K, Loynes CA et al (2019) 15-keto-prostaglandin E2 activates host peroxisome proliferator-activated receptor gamma (PPAR-\u03b3) to promote Cryptococcus neoformans growth during infection. PLoS Pathog 15(3):e1007597","journal-title":"PLoS Pathog"},{"key":"4_CR10","doi-asserted-by":"crossref","unstructured":"Singulani JL, Oliveira LT, Ramos MD et al (2021) The antimicrobial peptide MK58911-NH2 acts on planktonic, biofilm, and Intramacrophage cells of Cryptococcus neoformans. Antimicrob Agents Chemother","DOI":"10.1128\/AAC.00904-21"},{"key":"4_CR11","doi-asserted-by":"crossref","unstructured":"Gibson JF, Bojarczuk A, Evans RJ et al (2017) Dissemination of Cryptococcus neoformans via localised proliferation and blockage of blood vessels. PLoS Pathog","DOI":"10.1101\/184200"},{"issue":"2","key":"4_CR12","doi-asserted-by":"publisher","first-page":"bio030494","DOI":"10.1242\/bio.030494","volume":"7","author":"LM van Leeuwen","year":"2018","unstructured":"van Leeuwen LM, Evans RJ, Jim KK et al (2018) A transgenic zebrafish model for the in vivo study of the blood and choroid plexus brain barriers using claudin 5. Biol Open 7(2):bio030494","journal-title":"Biol Open"},{"issue":"68","key":"4_CR13","doi-asserted-by":"publisher","first-page":"1531","DOI":"10.1002\/glia.23829","volume":"2020","author":"N Hamilton","year":"2020","unstructured":"Hamilton N, Rutherford HA, Petts JJ et al (2020) The failure of microglia to digest developmental apoptotic cells contributes to the pathology of RNASET2-deficient leukoencephalopathy. Glia 2020(68):1531\u20131545","journal-title":"Glia"},{"key":"4_CR14","doi-asserted-by":"crossref","DOI":"10.1093\/oso\/9780199638086.001.0001","volume-title":"Zebrafish: a practical approach","author":"C N\u00fcsslein-Volhard","year":"2002","unstructured":"N\u00fcsslein-Volhard C, Dahm R (2002) Zebrafish: a practical approach. Oxford University Press"},{"key":"4_CR15","doi-asserted-by":"publisher","first-page":"e00310","DOI":"10.1128\/mBio.00310-11","volume":"3","author":"CA Morrow","year":"2012","unstructured":"Morrow CA, Lee IR, Chow EW et al (2012) A unique chromosomal rearrangement in the Cryptococcus neoformans var. grubii type strain enhances key phenotypes associated with virulence. MBio 3:e00310\u2013e00311","journal-title":"MBio"},{"issue":"1","key":"4_CR16","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1006\/dbio.1996.8495","volume":"183","author":"B Fouquet","year":"1997","unstructured":"Fouquet B, Weinstein BM, Serluca FC et al (1997) Vessel patterning in the embryo of the zebrafish: guidance by notochord. Dev Biol 183(1):37\u201348","journal-title":"Dev Biol"},{"key":"4_CR17","doi-asserted-by":"crossref","unstructured":"Kugler E, Snodgrass R, Bowley G et al (2021) The effect of absent blood flow on the zebrafish cerebral and trunk vasculature. Vasc Biol 3(1)","DOI":"10.1530\/VB-21-0009"},{"issue":"21","key":"4_CR18","doi-asserted-by":"publisher","first-page":"5281","DOI":"10.1242\/dev.00733","volume":"130","author":"S Isogai","year":"2003","unstructured":"Isogai S, Lawson ND, Torrealday S et al (2003) Angiogenic network formation in the developing vertebrate trunk. Development 130(21):5281\u20135290","journal-title":"Development"},{"issue":"2","key":"4_CR19","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1016\/j.ydbio.2019.03.005","volume":"457","author":"C Qui\u00f1onez-Silvero","year":"2020","unstructured":"Qui\u00f1onez-Silvero C, H\u00fcbner K, Herzog W et al (2020) Development of the brain vasculature and the blood-brain barrier in zebrafish. Dev Biol 457(2):181\u2013190","journal-title":"Dev Biol"},{"key":"4_CR20","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1016\/bs.ctdb.2015.07.001","volume":"115","author":"L Mork","year":"2015","unstructured":"Mork L, Crump G (2015) Zebrafish craniofacial development. A window into early patterning. Curr Top Dev Biol 115:235\u2013269","journal-title":"Curr Top Dev Biol"},{"issue":"10","key":"4_CR21","doi-asserted-by":"publisher","first-page":"2111","DOI":"10.1242\/dev.063933","volume":"138","author":"J Krueger","year":"2011","unstructured":"Krueger J, Liu D, Scholz K et al (2011) Flt1 acts as a negative regulator of tip cell formation and branching morphogenesis in the zebrafish embryo. Development 138(10):2111\u20132120","journal-title":"Development"}],"container-title":["Methods in Molecular Biology","Antifungal Immunity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/978-1-0716-3199-7_4","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,12]],"date-time":"2023-12-12T05:09:14Z","timestamp":1702357754000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/978-1-0716-3199-7_4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023]]},"ISBN":["9781071631980","9781071631997"],"references-count":21,"URL":"https:\/\/doi.org\/10.1007\/978-1-0716-3199-7_4","relation":{},"ISSN":["1064-3745","1940-6029"],"issn-type":[{"value":"1064-3745","type":"print"},{"value":"1940-6029","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023]]},"assertion":[{"value":"6 May 2023","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}}]}}