{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T22:06:49Z","timestamp":1773871609383,"version":"3.50.1"},"publisher-location":"New York, NY","reference-count":16,"publisher":"Springer US","isbn-type":[{"value":"9781071634240","type":"print"},{"value":"9781071634257","type":"electronic"}],"license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023]]},"DOI":"10.1007\/978-1-0716-3425-7_10","type":"book-chapter","created":{"date-parts":[[2023,9,9]],"date-time":"2023-09-09T12:02:01Z","timestamp":1694260921000},"page":"121-129","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Preparation of Human Olfactory Epithelial Biopsies for Downstream Analysis"],"prefix":"10.1007","author":[{"given":"Rhea","family":"Choi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tiffany","family":"Ko","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John B.","family":"Finlay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ralph Abi","family":"Hachem","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Jang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bradley J.","family":"Goldstein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2023,9,10]]},"reference":[{"issue":"4","key":"10_CR1","doi-asserted-by":"publisher","first-page":"1034","DOI":"10.1002\/cne.24105","volume":"525","author":"JE Schwob","year":"2017","unstructured":"Schwob JE et al (2017) Stem and progenitor cells of the mammalian olfactory epithelium: Taking poietic license. J Comp Neurol 525(4):1034\u20131054","journal-title":"J Comp Neurol"},{"issue":"3","key":"10_CR2","doi-asserted-by":"publisher","first-page":"1606","DOI":"10.1152\/jn.1997.77.3.1606","volume":"77","author":"NE Rawson","year":"1997","unstructured":"Rawson NE et al (1997) Selectivity and response characteristics of human olfactory neurons. J Neurophysiol 77(3):1606\u20131613","journal-title":"J Neurophysiol"},{"issue":"3 Pt 1","key":"10_CR3","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1097\/00005537-200003000-00016","volume":"110","author":"DA Leopold","year":"2000","unstructured":"Leopold DA et al (2000) Anterior distribution of human olfactory epithelium. Laryngoscope 110(3 Pt 1):417\u2013421","journal-title":"Laryngoscope"},{"issue":"7 Pt 1","key":"10_CR4","doi-asserted-by":"publisher","first-page":"1183","DOI":"10.1097\/00005537-200207000-00007","volume":"112","author":"AP Lane","year":"2002","unstructured":"Lane AP et al (2002) The superior turbinate as a source of functional human olfactory receptor neurons. Laryngoscope 112(7 Pt 1):1183\u20131189","journal-title":"Laryngoscope"},{"key":"10_CR5","doi-asserted-by":"publisher","DOI":"10.1002\/9781118971758","volume-title":"Handbook of Olfaction and Gustation","author":"RL Doty","year":"2015","unstructured":"Doty RL (2015) Handbook of Olfaction and Gustation, 3rd edn. John Wiley & Sons, Incorporated","edition":"3"},{"issue":"1","key":"10_CR6","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1002\/lio2.135","volume":"3","author":"R Choi","year":"2018","unstructured":"Choi R, Goldstein BJ (2018) Olfactory epithelium: Cells, clinical disorders, and insights from an adult stem cell niche. Laryngoscope Investig Otolaryngol 3(1):35\u201342","journal-title":"Laryngoscope Investig Otolaryngol"},{"issue":"8","key":"10_CR7","doi-asserted-by":"publisher","first-page":"1687","DOI":"10.1002\/lary.21856","volume":"121","author":"EH Holbrook","year":"2011","unstructured":"Holbrook EH et al (2011) Immunohistochemical characterization of human olfactory tissue. Laryngoscope 121(8):1687\u20131701","journal-title":"Laryngoscope"},{"issue":"12","key":"10_CR8","doi-asserted-by":"publisher","first-page":"2144","DOI":"10.1097\/01.MLG.0000181493.83661.CE","volume":"115","author":"EH Holbrook","year":"2005","unstructured":"Holbrook EH, Leopold DA, Schwob JE (2005) Abnormalities of axon growth in human olfactory mucosa. Laryngoscope 115(12):2144\u20132154","journal-title":"Laryngoscope"},{"issue":"3","key":"10_CR9","doi-asserted-by":"publisher","first-page":"323","DOI":"10.1038\/s41593-020-0587-9","volume":"23","author":"MA Durante","year":"2020","unstructured":"Durante MA et al (2020) Single-cell analysis of olfactory neurogenesis and differentiation in adult humans. Nat Neurosci 23(3):323\u2013326","journal-title":"Nat Neurosci"},{"key":"10_CR10","doi-asserted-by":"crossref","unstructured":"Oliva AD et al (2022) Aging-related olfactory loss is associated with olfactory stem cell transcriptional alterations in humans. J Clin Invest","DOI":"10.1101\/2021.08.09.455538"},{"issue":"676","key":"10_CR11","doi-asserted-by":"publisher","first-page":"eadd0484","DOI":"10.1126\/scitranslmed.add0484","volume":"14","author":"JB Finlay","year":"2022","unstructured":"Finlay JB et al (2022) Persistent post-COVID-19 smell loss is associated with immune cell infiltration and altered gene expression in olfactory epithelium. Sci Transl Med 14(676):eadd0484","journal-title":"Sci Transl Med"},{"issue":"6","key":"10_CR12","doi-asserted-by":"publisher","first-page":"519","DOI":"10.1056\/NEJMoa1315200","volume":"371","author":"CD Orru","year":"2014","unstructured":"Orru CD et al (2014) A test for Creutzfeldt-Jakob disease using nasal brushings. N Engl J Med 371(6):519\u2013529","journal-title":"N Engl J Med"},{"key":"10_CR13","doi-asserted-by":"publisher","first-page":"145","DOI":"10.3389\/fnins.2020.00145","volume":"14","author":"L Brozzetti","year":"2020","unstructured":"Brozzetti L et al (2020) Neurodegeneration-Associated Proteins in Human Olfactory Neurons Collected by Nasal Brushing. Front Neurosci 14:145","journal-title":"Front Neurosci"},{"issue":"6","key":"10_CR14","doi-asserted-by":"publisher","first-page":"646","DOI":"10.1002\/alr.21711","volume":"6","author":"EH Holbrook","year":"2016","unstructured":"Holbrook EH, Rebeiz L, Schwob JE (2016) Office-based olfactory mucosa biopsies. Int Forum Allergy Rhinol 6(6):646\u2013653","journal-title":"Int Forum Allergy Rhinol"},{"issue":"10","key":"10_CR15","doi-asserted-by":"publisher","first-page":"641","DOI":"10.1001\/archotol.1984.00800360013003","volume":"110","author":"T Nakashima","year":"1984","unstructured":"Nakashima T, Kimmelman CP, Snow JB Jr (1984) Structure of human fetal and adult olfactory neuroepithelium. Arch Otolaryngol 110(10):641\u2013646","journal-title":"Arch Otolaryngol"},{"issue":"7","key":"10_CR16","doi-asserted-by":"publisher","first-page":"731","DOI":"10.1001\/archotol.1992.01880070061012","volume":"118","author":"SI Paik","year":"1992","unstructured":"Paik SI et al (1992) Human olfactory biopsy. The influence of age and receptor distribution. Arch Otolaryngol Head Neck Surg 118(7):731\u2013738","journal-title":"Arch Otolaryngol Head Neck Surg"}],"container-title":["Methods in Molecular Biology","The Olfactory System"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/978-1-0716-3425-7_10","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,11]],"date-time":"2023-10-11T10:08:08Z","timestamp":1697018888000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/978-1-0716-3425-7_10"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023]]},"ISBN":["9781071634240","9781071634257"],"references-count":16,"URL":"https:\/\/doi.org\/10.1007\/978-1-0716-3425-7_10","relation":{},"ISSN":["1064-3745","1940-6029"],"issn-type":[{"value":"1064-3745","type":"print"},{"value":"1940-6029","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023]]},"assertion":[{"value":"10 September 2023","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}}]}}