{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T06:11:17Z","timestamp":1776147077341,"version":"3.50.1"},"publisher-location":"New York, NY","reference-count":18,"publisher":"Springer US","isbn-type":[{"value":"9781071638453","type":"print"},{"value":"9781071638460","type":"electronic"}],"license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024]]},"DOI":"10.1007\/978-1-0716-3846-0_15","type":"book-chapter","created":{"date-parts":[[2024,4,27]],"date-time":"2024-04-27T11:01:52Z","timestamp":1714215712000},"page":"205-217","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Porcine Model of Hypertrophy-Independent Left Ventricular Stiffening via Repetitive Pressure Overload"],"prefix":"10.1007","author":[{"given":"Emily R.","family":"Hudson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian R.","family":"Weil","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,4,28]]},"reference":[{"issue":"2","key":"15_CR1","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1016\/j.jchf.2013.10.006","volume":"2","author":"J Butler","year":"2014","unstructured":"Butler J, Fonarow GC, Zile MR, Lam CS, Roessig L, Schelbert EB, Shah SJ, Ahmed A, Bonow RO, Cleland JG, Cody RJ, Chioncel O, Collins SP, Dunnmon P, Filippatos G, Lefkowitz MP, Marti CN, McMurray JJ, Misselwitz F, Nodari S, O'Connor C, Pfeffer MA, Pieske B, Pitt B, Rosano G, Sabbah HN, Senni M, Solomon SD, Stockbridge N, Teerlink JR, Georgiopoulou VV, Gheorghiade M (2014) Developing therapies for heart failure with preserved ejection fraction: current state and future directions. JACC Heart Fail 2(2):97\u2013112. https:\/\/doi.org\/10.1016\/j.jchf.2013.10.006","journal-title":"JACC Heart Fail"},{"issue":"1","key":"15_CR2","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1161\/CIRCRESAHA.115.302922","volume":"115","author":"K Sharma","year":"2014","unstructured":"Sharma K, Kass DA (2014) Heart failure with preserved ejection fraction: mechanisms, clinical features, and therapies. Circ Res 115(1):79\u201396. https:\/\/doi.org\/10.1161\/CIRCRESAHA.115.302922","journal-title":"Circ Res"},{"issue":"5","key":"15_CR3","doi-asserted-by":"publisher","first-page":"588","DOI":"10.1161\/CIRCHEARTFAILURE.109.930701","volume":"3","author":"BA Borlaug","year":"2010","unstructured":"Borlaug BA, Nishimura RA, Sorajja P, Lam CS, Redfield MM (2010) Exercise hemodynamics enhance diagnosis of early heart failure with preserved ejection fraction. Circ Heart Fail 3(5):588\u2013595. https:\/\/doi.org\/10.1161\/CIRCHEARTFAILURE.109.930701","journal-title":"Circ Heart Fail"},{"issue":"19","key":"15_CR4","doi-asserted-by":"publisher","first-page":"1868","DOI":"10.1056\/NEJMcp1511175","volume":"375","author":"MM Redfield","year":"2016","unstructured":"Redfield MM (2016) Heart failure with preserved ejection fraction. N Engl J Med 375(19):1868\u20131877. https:\/\/doi.org\/10.1056\/NEJMcp1511175","journal-title":"N Engl J Med"},{"issue":"4","key":"15_CR5","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1016\/j.jacc.2013.02.092","volume":"62","author":"WJ Paulus","year":"2013","unstructured":"Paulus WJ, Tschope C (2013) A novel paradigm for heart failure with preserved ejection fraction: comorbidities drive myocardial dysfunction and remodeling through coronary microvascular endothelial inflammation. J Am Coll Cardiol 62(4):263\u2013271. https:\/\/doi.org\/10.1016\/j.jacc.2013.02.092","journal-title":"J Am Coll Cardiol"},{"issue":"5","key":"15_CR6","doi-asserted-by":"publisher","first-page":"447","DOI":"10.1016\/j.jacc.2013.09.052","volume":"63","author":"E Kraigher-Krainer","year":"2014","unstructured":"Kraigher-Krainer E, Shah AM, Gupta DK, Santos A, Claggett B, Pieske B, Zile MR, Voors AA, Lefkowitz MP, Packer M, McMurray JJ, Solomon SD, Investigators P (2014) Impaired systolic function by strain imaging in heart failure with preserved ejection fraction. J Am Coll Cardiol 63(5):447\u2013456. https:\/\/doi.org\/10.1016\/j.jacc.2013.09.052","journal-title":"J Am Coll Cardiol"},{"issue":"6","key":"15_CR7","doi-asserted-by":"publisher","first-page":"522","DOI":"10.1161\/CIRCULATIONAHA.114.014420","volume":"131","author":"DW Kitzman","year":"2015","unstructured":"Kitzman DW, Upadhya B, Vasu S (2015) What the dead can teach the living: systemic nature of heart failure with preserved ejection fraction. Circulation 131(6):522\u2013524. https:\/\/doi.org\/10.1161\/CIRCULATIONAHA.114.014420","journal-title":"Circulation"},{"issue":"4","key":"15_CR8","doi-asserted-by":"publisher","first-page":"527","DOI":"10.1016\/j.jacbts.2019.04.002","volume":"4","author":"BR Weil","year":"2019","unstructured":"Weil BR, Techiryan G, Suzuki G, Konecny F, Canty JM Jr (2019) Adaptive reductions in left ventricular diastolic compliance protect the heart from stretch-induced stunning. JACC Basic Transl Sci 4(4):527\u2013541. https:\/\/doi.org\/10.1016\/j.jacbts.2019.04.002","journal-title":"JACC Basic Transl Sci"},{"issue":"6","key":"15_CR9","doi-asserted-by":"publisher","first-page":"951","DOI":"10.1016\/j.yjmcc.2011.02.016","volume":"50","author":"G Heusch","year":"2011","unstructured":"Heusch G, Skyschally A, Schulz R (2011) The in-situ pig heart with regional ischemia\/reperfusion \u2013 ready for translation. J Mol Cell Cardiol 50(6):951\u2013963. https:\/\/doi.org\/10.1016\/j.yjmcc.2011.02.016","journal-title":"J Mol Cell Cardiol"},{"issue":"25","key":"15_CR10","doi-asserted-by":"publisher","first-page":"2906","DOI":"10.1016\/j.jacc.2018.04.029","volume":"71","author":"BR Weil","year":"2018","unstructured":"Weil BR, Suzuki G, Young RF, Iyer V, Canty JM Jr (2018) Troponin release and reversible left ventricular dysfunction after transient pressure overload. J Am Coll Cardiol 71(25):2906\u20132916. https:\/\/doi.org\/10.1016\/j.jacc.2018.04.029","journal-title":"J Am Coll Cardiol"},{"issue":"1","key":"15_CR11","doi-asserted-by":"publisher","first-page":"315","DOI":"10.1161\/01.CIR.83.1.315","volume":"83","author":"ET van der Velde","year":"1991","unstructured":"van der Velde ET, Burkhoff D, Steendijk P, Karsdon J, Sagawa K, Baan J (1991) Nonlinearity and load sensitivity of end-systolic pressure-volume relation of canine left ventricle in vivo. Circulation 83(1):315\u2013327","journal-title":"Circulation"},{"issue":"2","key":"15_CR12","doi-asserted-by":"publisher","first-page":"H501","DOI":"10.1152\/ajpheart.00138.2005","volume":"289","author":"D Burkhoff","year":"2005","unstructured":"Burkhoff D, Mirsky I, Suga H (2005) Assessment of systolic and diastolic ventricular properties via pressure-volume analysis: a guide for clinical, translational, and basic researchers. Am J Physiol Heart Circ Physiol 289(2):H501\u2013H512. https:\/\/doi.org\/10.1152\/ajpheart.00138.2005","journal-title":"Am J Physiol Heart Circ Physiol"},{"issue":"3","key":"15_CR13","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1093\/ehjci\/jev014","volume":"16","author":"RM Lang","year":"2015","unstructured":"Lang RM, Badano LP, Mor-Avi V, Afilalo J, Armstrong A, Ernande L, Flachskampf FA, Foster E, Goldstein SA, Kuznetsova T, Lancellotti P, Muraru D, Picard MH, Rietzschel ER, Rudski L, Spencer KT, Tsang W, Voigt JU (2015) Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. Eur Heart J Cardiovasc Imaging 16(3):233\u2013270. https:\/\/doi.org\/10.1093\/ehjci\/jev014","journal-title":"Eur Heart J Cardiovasc Imaging"},{"issue":"3","key":"15_CR14","doi-asserted-by":"publisher","first-page":"718","DOI":"10.1148\/radiol.09090527","volume":"254","author":"M Carlsson","year":"2010","unstructured":"Carlsson M, Saloner D, Martin AJ, Ursell PC, Saeed M (2010) Heterogeneous microinfarcts caused by coronary microemboli: evaluation with multidetector CT and MR imaging in a swine model. Radiology 254(3):718\u2013728. https:\/\/doi.org\/10.1148\/radiol.09090527","journal-title":"Radiology"},{"issue":"2","key":"15_CR15","doi-asserted-by":"publisher","first-page":"H345","DOI":"10.1152\/ajpheart.00124.2019","volume":"317","author":"G Suzuki","year":"2019","unstructured":"Suzuki G, Weil BR, Young RF, Fallavollita JA, Canty JM Jr (2019) Nonocclusive multivessel intracoronary infusion of allogeneic cardiosphere-derived cells early after reperfusion prevents remote zone myocyte loss and improves global left ventricular function in swine with myocardial infarction. Am J Physiol Heart Circ Physiol 317(2):H345\u2013H356. https:\/\/doi.org\/10.1152\/ajpheart.00124.2019","journal-title":"Am J Physiol Heart Circ Physiol"},{"issue":"3","key":"15_CR16","doi-asserted-by":"publisher","first-page":"H696","DOI":"10.1152\/ajpheart.00502.2019","volume":"318","author":"BR Weil","year":"2020","unstructured":"Weil BR, Suzuki G, Canty JM Jr (2020) Transmural variation in microvascular remodeling following percutaneous revascularization of a chronic coronary stenosis in swine. Am J Physiol Heart Circ Physiol 318(3):H696\u2013H705. https:\/\/doi.org\/10.1152\/ajpheart.00502.2019","journal-title":"Am J Physiol Heart Circ Physiol"},{"issue":"7","key":"15_CR17","doi-asserted-by":"publisher","first-page":"634","DOI":"10.1161\/CIRCRESAHA.115.306850","volume":"117","author":"BR Weil","year":"2015","unstructured":"Weil BR, Suzuki G, Leiker MM, Fallavollita JA, Canty JM Jr (2015) Comparative efficacy of intracoronary allogeneic mesenchymal stem cells and cardiosphere-derived cells in swine with hibernating myocardium. Circ Res 117(7):634\u2013644. https:\/\/doi.org\/10.1161\/CIRCRESAHA.115.306850","journal-title":"Circ Res"},{"issue":"9","key":"15_CR18","doi-asserted-by":"publisher","first-page":"H1407","DOI":"10.1152\/ajpheart.00542.2015","volume":"309","author":"M Schwarzl","year":"2015","unstructured":"Schwarzl M, Hamdani N, Seiler S, Alogna A, Manninger M, Reilly S, Zirngast B, Kirsch A, Steendijk P, Verderber J, Zweiker D, Eller P, Hofler G, Schauer S, Eller K, Maechler H, Pieske BM, Linke WA, Casadei B, Post H (2015) A porcine model of hypertensive cardiomyopathy: implications for heart failure with preserved ejection fraction. Am J Physiol Heart Circ Physiol 309(9):H1407\u2013H1418. https:\/\/doi.org\/10.1152\/ajpheart.00542.2015","journal-title":"Am J Physiol Heart Circ Physiol"}],"container-title":["Methods in Molecular Biology","Experimental Models of Cardiovascular Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/978-1-0716-3846-0_15","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,27]],"date-time":"2024-04-27T11:05:13Z","timestamp":1714215913000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/978-1-0716-3846-0_15"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024]]},"ISBN":["9781071638453","9781071638460"],"references-count":18,"URL":"https:\/\/doi.org\/10.1007\/978-1-0716-3846-0_15","relation":{},"ISSN":["1064-3745","1940-6029"],"issn-type":[{"value":"1064-3745","type":"print"},{"value":"1940-6029","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024]]},"assertion":[{"value":"28 April 2024","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}}]}}