{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,25]],"date-time":"2025-03-25T20:18:14Z","timestamp":1742933894034,"version":"3.40.3"},"publisher-location":"New York, NY","reference-count":17,"publisher":"Springer US","isbn-type":[{"type":"print","value":"9781071641873"},{"type":"electronic","value":"9781071641880"}],"license":[{"start":{"date-parts":[[2024,10,19]],"date-time":"2024-10-19T00:00:00Z","timestamp":1729296000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,10,19]],"date-time":"2024-10-19T00:00:00Z","timestamp":1729296000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025]]},"DOI":"10.1007\/978-1-0716-4188-0_17","type":"book-chapter","created":{"date-parts":[[2024,10,18]],"date-time":"2024-10-18T18:03:07Z","timestamp":1729274587000},"page":"395-409","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Genetic Manipulation and Extended Culture of Human Germinal Center B Cells to Model Lymphomagenesis"],"prefix":"10.1007","author":[{"given":"Rachel E.","family":"Fenner","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chun","family":"Gong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel J.","family":"Hodson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,10,19]]},"reference":[{"key":"17_CR1","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1146\/annurev-immunol-120419-022408","volume":"40","author":"GD Victora","year":"2022","unstructured":"Victora GD, Nussenzweig MC (2022) Germinal centers. Annu Rev Immunol 40:413\u2013442","journal-title":"Annu Rev Immunol"},{"key":"17_CR2","doi-asserted-by":"publisher","first-page":"240","DOI":"10.1111\/imr.12745","volume":"288","author":"L Pasqualucci","year":"2019","unstructured":"Pasqualucci L (2019) Molecular pathogenesis of germinal center-derived B cell lymphomas. Immunol Rev 288:240\u2013261","journal-title":"Immunol Rev"},{"key":"17_CR3","doi-asserted-by":"publisher","first-page":"565","DOI":"10.1146\/annurev-immunol-020711-075027","volume":"30","author":"AL Shaffer 3rd","year":"2012","unstructured":"Shaffer AL 3rd, Young RM, Staudt LM (2012) Pathogenesis of human B cell lymphomas. Annu Rev Immunol 30:565\u2013610","journal-title":"Annu Rev Immunol"},{"key":"17_CR4","doi-asserted-by":"publisher","first-page":"176","DOI":"10.1038\/ng.2856","volume":"46","author":"J Okosun","year":"2014","unstructured":"Okosun J, Bodor C, Wang J et al (2014) Integrated genomic analysis identifies recurrent mutations and evolution patterns driving the initiation and progression of follicular lymphoma. Nat Genet 46:176\u2013181","journal-title":"Nat Genet"},{"key":"17_CR5","doi-asserted-by":"publisher","first-page":"5716","DOI":"10.1182\/bloodadvances.2021005284","volume":"6","author":"S Crouch","year":"2022","unstructured":"Crouch S, Painter D, Barrans SL et al (2022) Molecular subclusters of follicular lymphoma: a report from the United Kingdom\u2019s Haematological Malignancy Research Network. Blood Adv 6:5716\u20135731","journal-title":"Blood Adv"},{"key":"17_CR6","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1182\/blood.2022018719","volume":"142","author":"K Dreval","year":"2023","unstructured":"Dreval K, Hilton LK, Cruz M et al (2023) Genetic subdivisions of follicular lymphoma defined by distinct coding and noncoding mutation patterns. Blood 142:561\u2013573","journal-title":"Blood"},{"key":"17_CR7","doi-asserted-by":"publisher","first-page":"904","DOI":"10.1182\/blood.2022016534","volume":"141","author":"N Thomas","year":"2023","unstructured":"Thomas N, Dreval K, Gerhard DS et al (2023) Genetic subgroups inform on pathobiology in adult and pediatric Burkitt lymphoma. Blood 141:904\u2013916","journal-title":"Blood"},{"key":"17_CR8","doi-asserted-by":"publisher","first-page":"1313","DOI":"10.1182\/blood-2018-09-871418","volume":"133","author":"BM Grande","year":"2019","unstructured":"Grande BM, Gerhard DS, Jiang A et al (2019) Genome-wide discovery of somatic coding and noncoding mutations in pediatric endemic and sporadic Burkitt lymphoma. Blood 133:1313\u20131324","journal-title":"Blood"},{"key":"17_CR9","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1038\/nature11378","volume":"490","author":"R Schmitz","year":"2012","unstructured":"Schmitz R, Young RM, Ceribelli M et al (2012) Burkitt lymphoma pathogenesis and therapeutic targets from structural and functional genomics. Nature 490:116\u2013120","journal-title":"Nature"},{"key":"17_CR10","doi-asserted-by":"publisher","first-page":"1396","DOI":"10.1056\/NEJMoa1801445","volume":"378","author":"R Schmitz","year":"2018","unstructured":"Schmitz R, Wright GW, Huang DW et al (2018) Genetics and pathogenesis of diffuse large B-cell lymphoma. N Engl J Med 378:1396\u20131407","journal-title":"N Engl J Med"},{"key":"17_CR11","doi-asserted-by":"publisher","first-page":"1759","DOI":"10.1182\/blood.2019003535","volume":"135","author":"SE Lacy","year":"2020","unstructured":"Lacy SE, Barrans SL, Beer PA et al (2020) Targeted sequencing in DLBCL, molecular subtypes, and outcomes: a Haematological Malignancy Research Network report. Blood 135:1759\u20131771","journal-title":"Blood"},{"key":"17_CR12","doi-asserted-by":"publisher","first-page":"4001","DOI":"10.1038\/s41467-018-06354-3","volume":"9","author":"SE Arthur","year":"2018","unstructured":"Arthur SE, Jiang A, Grande BM et al (2018) Genome-wide discovery of somatic regulatory variants in diffuse large B-cell lymphoma. Nat Commun 9:4001","journal-title":"Nat Commun"},{"key":"17_CR13","doi-asserted-by":"publisher","first-page":"679","DOI":"10.1038\/s41591-018-0016-8","volume":"24","author":"B Chapuy","year":"2018","unstructured":"Chapuy B, Stewart C, Dunford AJ et al (2018) Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes. Nat Med 24:679\u2013690","journal-title":"Nat Med"},{"key":"17_CR14","doi-asserted-by":"publisher","first-page":"4543","DOI":"10.1038\/s41467-019-12494-x","volume":"10","author":"R Caeser","year":"2019","unstructured":"Caeser R, Di Re M, Krupka JA et al (2019) Genetic modification of primary human B cells to model high-grade lymphoma. Nat Commun 10:4543","journal-title":"Nat Commun"},{"key":"17_CR15","doi-asserted-by":"publisher","first-page":"2499","DOI":"10.1038\/s41596-021-00506-4","volume":"16","author":"R Caeser","year":"2021","unstructured":"Caeser R, Gao J, Di Re M et al (2021) Genetic manipulation and immortalized culture of ex vivo primary human germinal center B cells. Nat Protoc 16:2499\u20132519","journal-title":"Nat Protoc"},{"issue":"4059-4075","key":"17_CR16","volume":"81","author":"C Gong","year":"2021","unstructured":"Gong C, Krupka JA, Gao J et al (2021) Sequential inverse dysregulation of the RNA helicases DDX3X and DDX3Y facilitates MYC-driven lymphomagenesis. Mol Cell 81(4059-4075):e4011","journal-title":"Mol Cell"},{"key":"17_CR17","doi-asserted-by":"publisher","first-page":"6220","DOI":"10.1038\/s41467-022-33739-2","volume":"13","author":"M Mangolini","year":"2022","unstructured":"Mangolini M, Maiques-Diaz A, Charalampopoulou S et al (2022) Viral transduction of primary human lymphoma B cells reveals mechanisms of NOTCH-mediated immune escape. Nat Commun 13:6220","journal-title":"Nat Commun"}],"container-title":["Methods in Molecular Biology","Lymphoma"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/978-1-0716-4188-0_17","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,18]],"date-time":"2024-10-18T18:06:04Z","timestamp":1729274764000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/978-1-0716-4188-0_17"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,19]]},"ISBN":["9781071641873","9781071641880"],"references-count":17,"URL":"https:\/\/doi.org\/10.1007\/978-1-0716-4188-0_17","relation":{},"ISSN":["1064-3745","1940-6029"],"issn-type":[{"type":"print","value":"1064-3745"},{"type":"electronic","value":"1940-6029"}],"subject":[],"published":{"date-parts":[[2024,10,19]]},"assertion":[{"value":"19 October 2024","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}}]}}