{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T17:44:20Z","timestamp":1793382260446,"version":"4.5.0"},"publisher-location":"New York, NY","reference-count":59,"publisher":"Springer US","isbn-type":[{"value":"9781071641996","type":"print"},{"value":"9781071642009","type":"electronic"}],"license":[{"start":{"date-parts":[[2024,11,16]],"date-time":"2024-11-16T00:00:00Z","timestamp":1731715200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,11,16]],"date-time":"2024-11-16T00:00:00Z","timestamp":1731715200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025]]},"DOI":"10.1007\/978-1-0716-4200-9_2","type":"book-chapter","created":{"date-parts":[[2024,11,15]],"date-time":"2024-11-15T01:08:17Z","timestamp":1731632897000},"page":"15-36","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Personality and Psychoneuroimmunology: A Systems Biology Perspective"],"prefix":"10.1007","author":[{"given":"Qing","family":"Yan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,11,16]]},"reference":[{"key":"2_CR1","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/978-1-4939-7828-1_1","volume":"1781","author":"Q Yan","year":"2018","unstructured":"Yan Q (2018) Stress and systemic inflammation: Yin-Yang dynamics in health and diseases. Methods Mol Biol 1781:3\u201320","journal-title":"Methods Mol Biol"},{"key":"2_CR2","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1007\/978-1-4939-7828-1_5","volume":"1781","author":"Q Yan","year":"2018","unstructured":"Yan Q (2018) Neuroimmune imbalances and Yin-Yang dynamics in stress, anxiety, and depression. Methods Mol Biol 1781:77\u201385","journal-title":"Methods Mol Biol"},{"key":"2_CR3","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.jrp.2016.07.008","volume":"64","author":"GS Shields","year":"2016","unstructured":"Shields GS, Toussaint LL, Slavich GM (2016) Stress-related changes in personality: a longitudinal study of perceived stress and trait pessimism. J Res Pers 64:61\u201368","journal-title":"J Res Pers"},{"key":"2_CR4","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1159\/000288920","volume":"62","author":"M Biondi","year":"1994","unstructured":"Biondi M, Peronti M, Pacitti F et al (1994) Personality, endocrine and immune changes after eight months in healthy individuals under normal daily stress. Psychother Psychosom 62:176\u2013184","journal-title":"Psychother Psychosom"},{"key":"2_CR5","first-page":"66","volume":"24","author":"A O\u017eura","year":"2012","unstructured":"O\u017eura A, Ihan A, Musek J (2012) Can the big five factors of personality predict lymphocyte counts? Psychiatr Danub 24:66\u201372","journal-title":"Psychiatr Danub"},{"key":"2_CR6","doi-asserted-by":"crossref","unstructured":"Del Val C, D\u00edaz de la Guardia-Bol\u00edvar E, Zwir I et al (2024) Gene expression networks regulated by human personality. Mol Psychiatry 29:2241\u20132260","DOI":"10.1038\/s41380-024-02484-x"},{"key":"2_CR7","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1111\/gbb.12212","volume":"14","author":"HN Kim","year":"2015","unstructured":"Kim HN, Kim BH, Cho J et al (2015) Pathway analysis of genome-wide association datasets of personality traits. Genes Brain Behav 14:345\u2013356","journal-title":"Genes Brain Behav"},{"key":"2_CR8","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1038\/mp.2013.109","volume":"19","author":"GH Lubke","year":"2014","unstructured":"Lubke GH, Laurin C, Amin N et al (2014) Genome-wide analyses of borderline personality features. Mol Psychiatry 19:923\u2013929","journal-title":"Mol Psychiatry"},{"key":"2_CR9","doi-asserted-by":"crossref","first-page":"4839","DOI":"10.2147\/PRBM.S423802","volume":"16","author":"A Bowirrat","year":"2023","unstructured":"Bowirrat A, Elman I, Dennen CA et al (2023) Neurogenetics and epigenetics of loneliness. Psychol Res Behav Manag 16:4839\u20134857","journal-title":"Psychol Res Behav Manag"},{"key":"2_CR10","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/j.euroneuro.2017.12.010","volume":"28","author":"N Knoblich","year":"2018","unstructured":"Knoblich N, Gundel F, Br\u00fcckmann C et al (2018) DNA methylation of APBA3 and MCF2 in borderline personality disorder: potential biomarkers for response to psychotherapy. Eur Neuropsychopharmacol 28:252\u2013263","journal-title":"Eur Neuropsychopharmacol"},{"key":"2_CR11","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.psyneuen.2014.08.014","volume":"50","author":"M Luchetti","year":"2014","unstructured":"Luchetti M, Barkley JM, Stephan Y et al (2014) Five-factor model personality traits and inflammatory markers: new data and a meta-analysis. Psychoneuroendocrinology 50:181\u2013193","journal-title":"Psychoneuroendocrinology"},{"key":"2_CR12","doi-asserted-by":"crossref","first-page":"205031211877499","DOI":"10.1177\/2050312118774990","volume":"6","author":"EK Graham","year":"2018","unstructured":"Graham EK, Bastarache ED, Milad E et al (2018) Physical activity mediates the association between personality and biomarkers of inflammation. SAGE Open Med 6:2050312118774990","journal-title":"SAGE Open Med"},{"key":"2_CR13","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.jpsychores.2011.10.001","volume":"72","author":"IHE Korenromp","year":"2012","unstructured":"Korenromp IHE, Grutters JC, van den Bosch JMM et al (2012) Post-inflammatory fatigue in sarcoidosis: personality profiles, psychological symptoms and stress hormones. J Psychosom Res 72:97\u2013102","journal-title":"J Psychosom Res"},{"key":"2_CR14","volume":"3","author":"C Gerritsen","year":"2020","unstructured":"Gerritsen C, Iyengar Y, DaSilva T et al (2020) Personality traits in psychosis and psychosis risk linked to TSPO expression: a neuroimmune marker. Pers Neurosci 3:e14","journal-title":"Pers Neurosci"},{"key":"2_CR15","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0176014","volume":"12","author":"VK Jandackova","year":"2017","unstructured":"Jandackova VK, Koenig J, Jarczok MN et al (2017) Potential biological pathways linking Type-D personality and poor health: a cross-sectional investigation. PLoS One 12:e0176014","journal-title":"PLoS One"},{"key":"2_CR16","doi-asserted-by":"crossref","first-page":"848","DOI":"10.5114\/aoms.2019.83146","volume":"16","author":"ME Talarowska","year":"2020","unstructured":"Talarowska ME, Kowalczyk M, Maes M et al (2020) Immune to happiness\u2014inflammatory process indicators and depressive personality traits. Arch Med Sci 16:848\u2013857","journal-title":"Arch Med Sci"},{"key":"2_CR17","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.biopsycho.2015.09.003","volume":"112","author":"JR Fanning","year":"2015","unstructured":"Fanning JR, Lee R, Gozal D et al (2015) Childhood trauma and parental style: relationship with markers of inflammation, oxidative stress, and aggression in healthy and personality disordered subjects. Biol Psychol 112:56\u201365","journal-title":"Biol Psychol"},{"key":"2_CR18","doi-asserted-by":"crossref","first-page":"pyv001","DOI":"10.1093\/ijnp\/pyv001","volume":"18","author":"EF Coccaro","year":"2015","unstructured":"Coccaro EF, Lee R, Coussons-Read M (2015) Cerebrospinal fluid inflammatory cytokines and aggression in personality disordered subjects. Int J Neuropsychopharmacol 18:pyv001","journal-title":"Int J Neuropsychopharmacol"},{"key":"2_CR19","first-page":"38","volume":"59","author":"G Ta\u015fci","year":"2022","unstructured":"Ta\u015fci G, Kaya \u015e, Korkmaz S et al (2022) Peripheral inflammatory parameters in patients with antisocial personality disorder. Noro Psikiyatr Ars 59:38\u201343","journal-title":"Noro Psikiyatr Ars"},{"key":"2_CR20","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.pharep.2014.08.006","volume":"67","author":"EA Og\u0142odek","year":"2015","unstructured":"Og\u0142odek EA, Szota AM, Just MJ et al (2015) The MCP-1, CCL-5 and SDF-1 chemokines as pro-inflammatory markers in generalized anxiety disorder and personality disorders. Pharmacol Rep 67:85\u201389","journal-title":"Pharmacol Rep"},{"key":"2_CR21","volume":"56","author":"ARCC Forte","year":"2023","unstructured":"Forte ARCC, Lessa PHC, Chaves Filho AJM et al (2023) Oxidative stress and inflammatory process in borderline personality disorder (BPD): a narrative review. Braz J Med Biol Res 56:e12484","journal-title":"Braz J Med Biol Res"},{"key":"2_CR22","doi-asserted-by":"crossref","first-page":"1610","DOI":"10.1016\/j.jpsychires.2012.09.009","volume":"46","author":"M D\u00edaz-Mars\u00e1","year":"2012","unstructured":"D\u00edaz-Mars\u00e1 M, Macdowell KS, Guemes I et al (2012) Activation of the cholinergic anti-inflammatory system in peripheral blood mononuclear cells from patients with borderline personality disorder. J Psychiatr Res 46:1610\u20131617","journal-title":"J Psychiatr Res"},{"key":"2_CR23","doi-asserted-by":"crossref","DOI":"10.1016\/j.psychres.2020.112782","volume":"284","author":"KS MacDowell","year":"2020","unstructured":"MacDowell KS, Mars\u00e1 MD, Buenache E et al (2020) Inflammatory and antioxidant pathway dysfunction in borderline personality disorder. Psychiatry Res 284:112782","journal-title":"Psychiatry Res"},{"key":"2_CR24","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1080\/15622975.2023.2183254","volume":"24","author":"JM L\u00f3pez-Villatoro","year":"2023","unstructured":"L\u00f3pez-Villatoro JM, D\u00edaz-Mars\u00e1 M, De la Torre-Luque A et al (2023) Inflammatory and oxidative endophenotypes in borderline personality disorder: a biomarker cluster analysis. World J Biol Psychiatry 24:587\u2013594","journal-title":"World J Biol Psychiatry"},{"key":"2_CR25","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1007\/s40519-019-00820-7","volume":"26","author":"LM Gonz\u00e1lez","year":"2021","unstructured":"Gonz\u00e1lez LM, Mota-Zamorano S, Garc\u00eda-Herr\u00e1iz A et al (2021) Genetic variants in dopamine pathways affect personality dimensions displayed by patients with eating disorders. Eat Weight Disord 26:93\u2013101","journal-title":"Eat Weight Disord"},{"key":"2_CR26","doi-asserted-by":"crossref","DOI":"10.1016\/j.psyneuen.2023.106383","volume":"158","author":"F Ruiz-Guerrero","year":"2023","unstructured":"Ruiz-Guerrero F, Gomez Del Barrio A, de la Torre-Luque A et al (2023) Oxidative stress and inflammatory pathways in female eating disorders and borderline personality disorders with emotional dysregulation as linking factors with impulsivity and trauma. Psychoneuroendocrinology 158:106383","journal-title":"Psychoneuroendocrinology"},{"key":"2_CR27","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1016\/j.biopsych.2005.08.001","volume":"59","author":"KG Kahl","year":"2006","unstructured":"Kahl KG, Bens S, Ziegler K et al (2006) Cortisol, the cortisol-dehydroepiandrosterone ratio, and pro-inflammatory cytokines in patients with current major depressive disorder comorbid with borderline personality disorder. Biol Psychiatry 59:667\u2013671","journal-title":"Biol Psychiatry"},{"key":"2_CR28","doi-asserted-by":"crossref","first-page":"1140","DOI":"10.1111\/jopy.12788","volume":"91","author":"MS Stendel","year":"2023","unstructured":"Stendel MS, Chavez RS (2023) Beyond the brain localization of complex traits: distributed white matter markers of personality. J Pers 91:1140\u20131151","journal-title":"J Pers"},{"key":"2_CR29","doi-asserted-by":"crossref","DOI":"10.1038\/tp.2015.188","volume":"5","author":"SM Shadli","year":"2015","unstructured":"Shadli SM, Glue P, McIntosh J et al (2015) An improved human anxiety process biomarker: characterization of frequency band, personality and pharmacology. Transl Psychiatry 5:e699","journal-title":"Transl Psychiatry"},{"key":"2_CR30","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.ebiom.2017.11.025","volume":"27","author":"MA Shakra","year":"2018","unstructured":"Shakra MA, Leyton M, Moghnieh H et al (2018) Neurobiological correlates and predictors of two distinct personality trait pathways to escalated alcohol use. EBioMedicine 27:86\u201393","journal-title":"EBioMedicine"},{"key":"2_CR31","doi-asserted-by":"crossref","DOI":"10.1016\/j.pnpbp.2020.110115","volume":"111","author":"AC Ruocco","year":"2021","unstructured":"Ruocco AC, Rodrigo AH, Lam J et al (2021) Neurophysiological biomarkers of response inhibition and the familial risk for borderline personality disorder. Prog Neuro-Psychopharmacol Biol Psychiatry 111:110115","journal-title":"Prog Neuro-Psychopharmacol Biol Psychiatry"},{"key":"2_CR32","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1111\/acps.12234","volume":"130","author":"E B\u00f8en","year":"2014","unstructured":"B\u00f8en E, Westlye LT, Elvs\u00e5shagen T et al (2014) Regional cortical thinning may be a biological marker for borderline personality disorder. Acta Psychiatr Scand 130:193\u2013204","journal-title":"Acta Psychiatr Scand"},{"key":"2_CR33","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1192\/bjp.bp.110.078485","volume":"197","author":"A Raine","year":"2010","unstructured":"Raine A, Lee L, Yang Y et al (2010) Neurodevelopmental marker for limbic maldevelopment in antisocial personality disorder and psychopathy. Br J Psychiatry 197:186\u2013192","journal-title":"Br J Psychiatry"},{"key":"2_CR34","doi-asserted-by":"crossref","first-page":"1797","DOI":"10.1038\/npp.2009.1","volume":"34","author":"LM Williams","year":"2009","unstructured":"Williams LM, Gatt JM, Kuan SA et al (2009) A polymorphism of the MAOA gene is associated with emotional brain markers and personality traits on an antisocial index. Neuropsychopharmacology 34:1797\u20131809","journal-title":"Neuropsychopharmacology"},{"key":"2_CR35","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1111\/j.1467-9450.2010.00844.x","volume":"52","author":"A Sandstr\u00f6m","year":"2011","unstructured":"Sandstr\u00f6m A, Peterson J, Sandstr\u00f6m E et al (2011) Cognitive deficits in relation to personality type and hypothalamic-pituitary-adrenal (HPA) axis dysfunction in women with stress-related exhaustion. Scand J Psychol 52:71\u201382","journal-title":"Scand J Psychol"},{"key":"2_CR36","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1007\/s00737-022-01241-9","volume":"25","author":"JA Monreal","year":"2022","unstructured":"Monreal JA, Salvat-Pujol N, Gonz\u00e1lez-Rodr\u00edguez A et al (2022) The relationship between sex, personality traits, and the hypothalamic-pituitary-adrenocortical axis. Arch Womens Ment Health 25:693\u2013703","journal-title":"Arch Womens Ment Health"},{"key":"2_CR37","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1080\/1354750X.2021.1919762","volume":"26","author":"H Roshanmehr","year":"2021","unstructured":"Roshanmehr H, Tavakoli R, Khaledi M et al (2021) Evaluating the activity of salivary enzymes as stress biomarkers under psychological stress and their relationship with rumination and personality traits. Biomarkers 26:477\u2013482","journal-title":"Biomarkers"},{"key":"2_CR38","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1111\/j.1601-183X.2006.00259.x","volume":"6","author":"D Wasserman","year":"2007","unstructured":"Wasserman D, Geijer T, Sokolowski M et al (2007) Genetic variation in the hypothalamic-pituitary-adrenocortical axis regulatory factor, T-box 19, and the angry\/hostility personality trait. Genes Brain Behav 6:321\u2013328","journal-title":"Genes Brain Behav"},{"key":"2_CR39","doi-asserted-by":"crossref","first-page":"2601","DOI":"10.2147\/NDT.S198804","volume":"15","author":"N Thomas","year":"2019","unstructured":"Thomas N, Gurvich C, Kulkarni J (2019) Borderline personality disorder, trauma, and the hypothalamus-pituitary-adrenal axis. Neuropsychiatr Dis Treat 15:2601\u20132612","journal-title":"Neuropsychiatr Dis Treat"},{"key":"2_CR40","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1016\/j.neubiorev.2018.11.008","volume":"96","author":"E Drews","year":"2019","unstructured":"Drews E, Fertuck EA, Koenig J et al (2019) Hypothalamic-pituitary-adrenal axis functioning in borderline personality disorder: a meta-analysis. Neurosci Biobehav Rev 96:316\u2013334","journal-title":"Neurosci Biobehav Rev"},{"key":"2_CR41","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1192\/bjp.bp.106.022590","volume":"190","author":"JL Carrasco","year":"2007","unstructured":"Carrasco JL, D\u00edaz-Mars\u00e1 M, Pastrana JI et al (2007) Hypothalamic-pituitary-adrenal axis response in borderline personality disorder without post-traumatic features. Br J Psychiatry 190:357\u2013358","journal-title":"Br J Psychiatry"},{"key":"2_CR42","doi-asserted-by":"crossref","first-page":"1102","DOI":"10.1016\/S0006-3223(02)01395-1","volume":"52","author":"T Rinne","year":"2002","unstructured":"Rinne T, de Kloet ER, Wouters L et al (2002) Hyperresponsiveness of hypothalamic-pituitary-adrenal axis to combined dexamethasone\/corticotropin-releasing hormone challenge in female borderline personality disorder subjects with a history of sustained childhood abuse. Biol Psychiatry 52:1102\u20131112","journal-title":"Biol Psychiatry"},{"key":"2_CR43","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1002\/hup.297","volume":"16","author":"I Schweitzer","year":"2001","unstructured":"Schweitzer I, Tuckwell V, Maguire K et al (2001) Personality pathology, depression and HPA axis functioning. Hum Psychopharmacol 16:303\u2013308","journal-title":"Hum Psychopharmacol"},{"key":"2_CR44","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.schres.2003.10.008","volume":"70","author":"V Mitropoulou","year":"2004","unstructured":"Mitropoulou V, Goodman M, Sevy S et al (2004) Effects of acute metabolic stress on the dopaminergic and pituitary-adrenal axis activity in patients with schizotypal personality disorder. Schizophr Res 70:27\u201331","journal-title":"Schizophr Res"},{"key":"2_CR45","doi-asserted-by":"crossref","first-page":"327","DOI":"10.3389\/fnhum.2019.00327","volume":"13","author":"V Zakopoulou","year":"2019","unstructured":"Zakopoulou V, Vlaikou AM, Darsinou M et al (2019) Linking early life hypothalamic-pituitary-adrenal axis functioning, brain asymmetries, and personality traits in dyslexia: an informative case study. Front Hum Neurosci 13:327","journal-title":"Front Hum Neurosci"},{"key":"2_CR46","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.psyneuen.2017.10.023","volume":"87","author":"A Piskunov","year":"2018","unstructured":"Piskunov A, Fust\u00e9 A, Teryaeva N et al (2018) The hypothalamic-pituitary-thyroid axis and personality in a sample of healthy subjects. Psychoneuroendocrinology 87:181\u2013187","journal-title":"Psychoneuroendocrinology"},{"key":"2_CR47","doi-asserted-by":"crossref","unstructured":"Sinai C, Hirvikoski T, Nordstr\u00f6m AL et al (2014) Hypothalamic pituitary thyroid axis and exposure to interpersonal violence in childhood among women with borderline personality disorder. Eur J Psychotraumatol:5","DOI":"10.3402\/ejpt.v5.23911"},{"key":"2_CR48","doi-asserted-by":"crossref","DOI":"10.1016\/j.pnpbp.2021.110345","volume":"111","author":"E Flach","year":"2021","unstructured":"Flach E, Koenig J, van der Venne P et al (2021) Hypothalamic-pituitary-thyroid axis function in female adolescent nonsuicidal self-injury and its association with comorbid borderline personality disorder and depression. Prog Neuro-Psychopharmacol Biol Psychiatry 111:110345","journal-title":"Prog Neuro-Psychopharmacol Biol Psychiatry"},{"key":"2_CR49","doi-asserted-by":"crossref","first-page":"131","DOI":"10.3390\/jpm12020131","volume":"12","author":"K Hayakawa","year":"2022","unstructured":"Hayakawa K, Watabe M, Horikawa H et al (2022) Low-density lipoprotein cholesterol is a possible blood biomarker of schizoid personality traits among females. J Pers Med 12:131","journal-title":"J Pers Med"},{"key":"2_CR50","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.2217\/fmb-2019-0143","volume":"15","author":"M Afzal","year":"2020","unstructured":"Afzal M, Mazhar SF, Sana S et al (2020) Neurological and cognitive significance of probiotics: a holy grail deciding individual personality. Future Microbiol 15:1059\u20131074","journal-title":"Future Microbiol"},{"key":"2_CR51","doi-asserted-by":"crossref","unstructured":"Johnson KVA (2020) Gut microbiome composition and diversity are related to human personality traits. Hum Microbiome J 15:None","DOI":"10.1016\/j.humic.2019.100069"},{"key":"2_CR52","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1016\/j.bbi.2017.12.012","volume":"69","author":"HN Kim","year":"2018","unstructured":"Kim HN, Yun Y, Ryu S et al (2018) Correlation between gut microbiota and personality in adults: a cross-sectional study. Brain Behav Immun 69:374\u2013385","journal-title":"Brain Behav Immun"},{"key":"2_CR53","doi-asserted-by":"crossref","DOI":"10.1016\/j.jpsychores.2022.110942","volume":"158","author":"H R\u00f6ssler","year":"2022","unstructured":"R\u00f6ssler H, Flasbeck V, Gatermann S et al (2022) Alterations of the gut microbiota in borderline personality disorder. J Psychosom Res 158:110942","journal-title":"J Psychosom Res"},{"key":"2_CR54","doi-asserted-by":"crossref","DOI":"10.1016\/j.pnpbp.2019.109782","volume":"98","author":"G Anderson","year":"2020","unstructured":"Anderson G (2020) Pathoetiology and pathophysiology of borderline personality: role of prenatal factors, gut microbiome, mu- and kappa-opioid receptors in amygdala-PFC interactions. Prog Neuro-Psychopharmacol Biol Psychiatry 98:109782","journal-title":"Prog Neuro-Psychopharmacol Biol Psychiatry"},{"key":"2_CR55","first-page":"611","volume":"30","author":"KM Fock","year":"2001","unstructured":"Fock KM, Chew CN, Tay LK et al (2001) Psychiatric illness, personality traits and the irritable bowel syndrome. Ann Acad Med Singap 30:611\u2013614","journal-title":"Ann Acad Med Singap"},{"key":"2_CR56","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1007\/s00535-022-01902-7","volume":"57","author":"SBU Jordi","year":"2022","unstructured":"Jordi SBU, Lang BM, Wyss J et al (2022) The personality traits activity, self-reproach, and negative affect jointly predict clinical recurrence, depressive symptoms, and low quality of life in inflammatory bowel disease patients. J Gastroenterol 57:848\u2013866","journal-title":"J Gastroenterol"},{"key":"2_CR57","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/978-1-62703-071-7_1","volume":"934","author":"Q Yan","year":"2012","unstructured":"Yan Q (2012) The role of psychoneuroimmunology in personalized and systems medicine. Methods Mol Biol 934:3\u201319","journal-title":"Methods Mol Biol"},{"key":"2_CR58","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1007\/978-1-0716-2573-6_11","volume":"2547","author":"Q Yan","year":"2022","unstructured":"Yan Q (2022) The Yin-Yang dynamics in cardiovascular pharmacogenomics and personalized medicine. Methods Mol Biol 2547:255\u2013266","journal-title":"Methods Mol Biol"},{"key":"2_CR59","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1016\/j.psyneuen.2012.11.014","volume":"38","author":"E Altmaier","year":"2013","unstructured":"Altmaier E, Emeny RT, Krumsiek J et al (2013) Metabolomic profiles in individuals with negative affectivity and social inhibition: a population-based study of type D personality. Psychoneuroendocrinology 38:1299\u20131309","journal-title":"Psychoneuroendocrinology"}],"container-title":["Methods in Molecular Biology","Psychoneuroimmunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/978-1-0716-4200-9_2","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,24]],"date-time":"2025-02-24T14:04:03Z","timestamp":1740405843000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/978-1-0716-4200-9_2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,16]]},"ISBN":["9781071641996","9781071642009"],"references-count":59,"URL":"https:\/\/doi.org\/10.1007\/978-1-0716-4200-9_2","relation":{},"ISSN":["1064-3745","1940-6029"],"issn-type":[{"value":"1064-3745","type":"print"},{"value":"1940-6029","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,16]]},"assertion":[{"value":"16 November 2024","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}}]}}