{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,12]],"date-time":"2025-06-12T04:12:22Z","timestamp":1749701542669,"version":"3.41.0"},"publisher-location":"New York, NY","reference-count":13,"publisher":"Springer US","isbn-type":[{"value":"9781071645338","type":"print"},{"value":"9781071645345","type":"electronic"}],"license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025]]},"DOI":"10.1007\/978-1-0716-4534-5_18","type":"book-chapter","created":{"date-parts":[[2025,6,11]],"date-time":"2025-06-11T14:45:25Z","timestamp":1749653125000},"page":"249-257","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Quantification of Melatonin with Immunoassay and Liquid Chromatography-Tandem Mass Spectrometry"],"prefix":"10.1007","author":[{"given":"Jonah","family":"Kutell","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Avani","family":"Singal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xing","family":"Du","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Krishna","family":"Kishor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,6,12]]},"reference":[{"issue":"3","key":"18_CR1","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1016\/j.biocel.2005.08.020","volume":"38","author":"R Hardeland","year":"2006","unstructured":"Hardeland R, Pandi-Perumal SR, Cardinali DP (2006) Melatonin. Int J Biochem Cell Biol 38(3):313\u2013316. https:\/\/doi.org\/10.1016\/j.biocel.2005.08.020","journal-title":"Int J Biochem Cell Biol"},{"issue":"1","key":"18_CR2","doi-asserted-by":"publisher","first-page":"66","DOI":"10.5664\/jcsm.27083","volume":"4","author":"S Benloucif","year":"2008","unstructured":"Benloucif S, Burgess HJ, Klerman EB, Lewy AJ, Middleton B, Murphy PJ et al (2008) Measuring melatonin in humans. J Clin Sleep Med 4(1):66\u201369. https:\/\/doi.org\/10.5664\/jcsm.27083","journal-title":"J Clin Sleep Med"},{"issue":"1","key":"18_CR3","doi-asserted-by":"publisher","DOI":"10.1111\/jpi.12657","volume":"69","author":"DJ Kennaway","year":"2020","unstructured":"Kennaway DJ (2020) Measuring melatonin by immunoassay. J Pineal Res 69(1):e12657. https:\/\/doi.org\/10.1111\/jpi.12657","journal-title":"J Pineal Res"},{"issue":"9","key":"18_CR4","doi-asserted-by":"publisher","first-page":"1167","DOI":"10.1111\/jpi.12794","volume":"36","author":"DJ Kennaway","year":"2019","unstructured":"Kennaway DJ (2019) Melatonin research in mice: a review. Chronobiol Int 36(9):1167\u20131183. https:\/\/doi.org\/10.1111\/jpi.12794","journal-title":"Chronobiol Int"},{"key":"18_CR5","doi-asserted-by":"publisher","first-page":"1142","DOI":"10.1007\/s12161-015-0288-2","volume":"9","author":"B Yin","year":"2016","unstructured":"Yin B, Li T, Li Z, Dang T, He P (2016) Determination of melatonin and its metabolites in biological fluids and eggs using high-performance liquid chromatography with fluorescence and quadrupole-orbitrap high-resolution mass spectrometry. Food Anal Methods 9:1142\u20131149. https:\/\/doi.org\/10.1007\/s12161-015-0288-2","journal-title":"Food Anal Methods"},{"key":"18_CR6","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2022.134606","volume":"404","author":"S Yao","year":"2023","unstructured":"Yao S, Liu X, Fu Y, Guan S, Liu Y, Yan L et al (2023) A rapid method to measure melatonin in biological fluids (milk and serum) with liquid chromatography-tandem mass spectrometry. Food Chem 404:134606. https:\/\/doi.org\/10.1016\/j.foodchem.2022.134606","journal-title":"Food Chem"},{"issue":"6","key":"18_CR7","doi-asserted-by":"publisher","first-page":"1916","DOI":"10.3390\/ijerph17061916","volume":"17","author":"B Rzepka-Migut","year":"2020","unstructured":"Rzepka-Migut B, Paprocka J (2020) Melatonin-measurement methods and the factors modifying the results. A systematic review of the literature. Int J Environ Res Public Health 17(6):1916. https:\/\/doi.org\/10.3390\/ijerph17061916","journal-title":"Int J Environ Res Public Health"},{"key":"18_CR8","doi-asserted-by":"publisher","first-page":"879","DOI":"10.1007\/s00381-010-1278-8","volume":"27","author":"EA De Almeida","year":"2011","unstructured":"De Almeida EA, Di Mascio P, Harumi T, Warren Spence D, Moscovitch A, Hardeland R et al (2011) Measurement of melatonin in body fluids: standards, protocols and procedures. Childs Nerv Syst 27:879\u2013891. https:\/\/doi.org\/10.1007\/s00381-010-1278-8","journal-title":"Childs Nerv Syst"},{"key":"18_CR9","unstructured":"Blood sampling: mouse. NC3Rs. (2013, December 11). https:\/\/nc3rs.org.uk\/3rs-resources\/blood-sampling\/blood-sampling-mouse#general-principles"},{"issue":"2","key":"18_CR10","doi-asserted-by":"publisher","first-page":"87","DOI":"10.4103\/0976-500X.72350","volume":"1","author":"S Parasuraman","year":"2010","unstructured":"Parasuraman S, Raveendran R, Kesavan R (2010) Blood sample collection in small laboratory animals. J Pharmacol Pharmacother 1(2):87. https:\/\/doi.org\/10.4103\/0976-500X.72350","journal-title":"J Pharmacol Pharmacother"},{"key":"18_CR11","unstructured":"Novolytix. (n.d.). https:\/\/www.novolytix.ch\/en\/RIA_melatonin"},{"issue":"42","key":"18_CR12","doi-asserted-by":"publisher","first-page":"12","DOI":"10.30744\/brjac.2179-3425.rv-143-2022","volume":"11","author":"G Monga","year":"2024","unstructured":"Monga G, Yerram S, Koppula S, Sindhu RK, Kumar S (2024) A brief assessment of the bioanalytical methods by using LC-MS\/MS for the quantitation of melatonin: a potential biomarker for sleep-related disorders. Braz J Anal Chem 11(42):12\u201332. https:\/\/doi.org\/10.30744\/brjac.2179-3425.rv-143-2022","journal-title":"Braz J Anal Chem"},{"key":"18_CR13","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1016\/j.jchromb.2019.01.002","volume":"1108","author":"C Domenech-Coca","year":"2019","unstructured":"Domenech-Coca C, Marin\u00e9-Casad\u00f3 R, Caimari A, Arola L, Del Bas JM, Blad\u00e9 C, Rodriguez-Naranjo MI (2019) Dual liquid-liquid extraction followed by LC-MS\/MS method for the simultaneous quantification of melatonin, cortisol, triiodothyronine, thyroxine and testosterone levels in serum: applications to a photoperiod study in rats. J Chromatogr B 1108:11\u201316. https:\/\/doi.org\/10.1016\/j.jchromb.2019.01.002","journal-title":"J Chromatogr B"}],"container-title":["Methods in Molecular Biology","Metabolomics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/978-1-0716-4534-5_18","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,11]],"date-time":"2025-06-11T14:45:26Z","timestamp":1749653126000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/978-1-0716-4534-5_18"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"ISBN":["9781071645338","9781071645345"],"references-count":13,"URL":"https:\/\/doi.org\/10.1007\/978-1-0716-4534-5_18","relation":{},"ISSN":["1064-3745","1940-6029"],"issn-type":[{"value":"1064-3745","type":"print"},{"value":"1940-6029","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025]]},"assertion":[{"value":"12 June 2025","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}}]}}