{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,27]],"date-time":"2025-05-27T04:09:08Z","timestamp":1748318948222,"version":"3.41.0"},"publisher-location":"New York, NY","reference-count":12,"publisher":"Springer US","isbn-type":[{"value":"9781071645734","type":"print"},{"value":"9781071645741","type":"electronic"}],"license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025]]},"DOI":"10.1007\/978-1-0716-4574-1_13","type":"book-chapter","created":{"date-parts":[[2025,5,26]],"date-time":"2025-05-26T09:36:40Z","timestamp":1748252200000},"page":"93-97","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["HPRT Mutation Assay for Chinese Hamster Ovary Cells"],"prefix":"10.1007","author":[{"given":"Takamitsu A.","family":"Kato","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,5,27]]},"reference":[{"key":"13_CR1","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1016\/S0092-8674(00)81683-9","volume":"100","author":"D Hanahan","year":"2000","unstructured":"Hanahan D, Weinberg RA (2000) The hallmarks of cancer. Cell 100:57\u201370","journal-title":"Cell"},{"key":"13_CR2","doi-asserted-by":"publisher","first-page":"18545","DOI":"10.1073\/pnas.1010978107","volume":"107","author":"I Bozic","year":"2010","unstructured":"Bozic I, Antal T, Ohtsuki H, Carter H, Kim D, Chen S et al (2010) Accumulation of driver and passenger mutations during tumor progression. Proc Natl Acad Sci U S A 107:18545\u201318550","journal-title":"Proc Natl Acad Sci U S A"},{"key":"13_CR3","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1016\/0027-5107(75)90258-4","volume":"30","author":"AG Knaap","year":"1975","unstructured":"Knaap AG, Simons JW (1975) A mutational assay system for L5178Y mouse lymphoma cells, using hypoxanthine-guanine-phosphoribosyl-transferase (HGPRT) -deficiency as marker. The occurrence of a long expression time for mutations induced by X-rays and EMS. Mutat Res 30:97\u2013110","journal-title":"Mutat Res"},{"key":"13_CR4","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/0092-8674(79)90182-X","volume":"16","author":"CT Caskey","year":"1979","unstructured":"Caskey CT, Kruh GD (1979) The HPRT locus. Cell 16:1\u20139","journal-title":"Cell"},{"key":"13_CR5","doi-asserted-by":"publisher","first-page":"1306","DOI":"10.1073\/pnas.61.4.1306","volume":"61","author":"EH Chu","year":"1968","unstructured":"Chu EH, Malling HV (1968) Mammalian cell genetics. II. Chemical induction of specific locus mutations in Chinese hamster cells in vitro. Proc Natl Acad Sci U S A 61:1306\u20131312","journal-title":"Proc Natl Acad Sci U S A"},{"key":"13_CR6","doi-asserted-by":"publisher","first-page":"1275","DOI":"10.1073\/pnas.60.4.1275","volume":"60","author":"FT Kao","year":"1968","unstructured":"Kao FT, Puck TT (1968) Genetics of somatic mammalian cells, VII. Induction and isolation of nutritional mutants in Chinese hamster cells. Proc Natl Acad Sci U S A 60:1275\u20131281","journal-title":"Proc Natl Acad Sci U S A"},{"key":"13_CR7","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1016\/0888-7543(90)90545-6","volume":"7","author":"RA Gibbs","year":"1990","unstructured":"Gibbs RA, Nguyen PN, Edwards A, Civitello AB, Caskey CT (1990) Multiplex DNA deletion detection and exon sequencing of the hypoxanthine phosphoribosyltransferase gene in Lesch-Nyhan families. Genomics 7:235\u2013244","journal-title":"Genomics"},{"key":"13_CR8","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1016\/0888-7543(91)90249-E","volume":"9","author":"BJ Rossiter","year":"1991","unstructured":"Rossiter BJ, Fuscoe JC, Muzny DM, Fox M, Caskey CT (1991) The Chinese hamster HPRT gene: restriction map, sequence analysis, and multiplex PCR deletion screen. Genomics 9:247\u2013256","journal-title":"Genomics"},{"key":"13_CR9","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1016\/0165-1161(80)90188-0","volume":"74","author":"LH Thompson","year":"1980","unstructured":"Thompson LH, Fong S, Brookman K (1980) Validation of conditions for efficient detection of HPRT and APRT mutations in suspension-cultured Chinese hamster ovary cells. Mutat Res 74:21\u201336","journal-title":"Mutat Res"},{"key":"13_CR10","doi-asserted-by":"crossref","unstructured":"Buglewicz DJ, Mussallem JT, Haskins AH, Su C, Maeda J, Kato TA (2020) Cytotoxicity and mutagenicity of narrowband UVB to mammalian cells. Genes (Basel):11","DOI":"10.3390\/genes11060646"},{"key":"13_CR11","doi-asserted-by":"crossref","unstructured":"Haskins JS, Su C, Maeda J, Walsh KD, Haskins AH, Allum AJ et al (2020) Evaluating the genotoxic and cytotoxic effects of thymidine analogs, 5-ethynyl-2\u2032-deoxyuridine and 5-bromo-2\u2032-deoxyurdine to mammalian cells. Int J Mol Sci:21","DOI":"10.3390\/ijms21186631"},{"key":"13_CR12","doi-asserted-by":"publisher","DOI":"10.1016\/j.mrgentox.2021.503416","volume":"872","author":"KD Walsh","year":"2021","unstructured":"Walsh KD, Burkhart EM, Nagai A, Aizawa Y, Kato TA (2021) Cytotoxicity and genotoxicity of blue LED light and protective effects of AA2G in mammalian cells and associated DNA repair deficient cell lines. Mutat Res Genet Toxicol Environ Mutagen 872:503416","journal-title":"Mutat Res Genet Toxicol Environ Mutagen"}],"container-title":["Methods in Molecular Biology","DNA Damage Detection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/978-1-0716-4574-1_13","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,26]],"date-time":"2025-05-26T09:36:41Z","timestamp":1748252201000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/978-1-0716-4574-1_13"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"ISBN":["9781071645734","9781071645741"],"references-count":12,"URL":"https:\/\/doi.org\/10.1007\/978-1-0716-4574-1_13","relation":{},"ISSN":["1064-3745","1940-6029"],"issn-type":[{"value":"1064-3745","type":"print"},{"value":"1940-6029","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025]]},"assertion":[{"value":"27 May 2025","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}}]}}