{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T08:15:36Z","timestamp":1778919336664,"version":"3.51.4"},"publisher-location":"New York, NY","reference-count":6,"publisher":"Springer US","isbn-type":[{"value":"9781071647370","type":"print"},{"value":"9781071647387","type":"electronic"}],"license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026]]},"DOI":"10.1007\/978-1-0716-4738-7_4","type":"book-chapter","created":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T22:28:59Z","timestamp":1759271339000},"page":"67-78","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Splice Modulation Studies Using Urine-Derived Cells"],"prefix":"10.1007","author":[{"given":"Katsuhiko","family":"Kunitake","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshitsugu","family":"Aoki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,10,1]]},"reference":[{"key":"4_CR1","doi-asserted-by":"publisher","first-page":"919","DOI":"10.1016\/0092-8674(87)90579-4","volume":"51","author":"EP Hoffman","year":"1987","unstructured":"Hoffman EP et al (1987) Dystrophin: the protein product of the Duchenne muscular dystrophy locus. Cell 51:919\u2013928","journal-title":"Cell"},{"key":"4_CR2","doi-asserted-by":"publisher","first-page":"595","DOI":"10.1016\/S0140-6736(11)60756-3","volume":"378","author":"S Cirak","year":"2011","unstructured":"Cirak S et al (2011) Exon skipping and dystrophin restoration in patients with Duchenne muscular dystrophy after systemic phosphorodiamidate morpholino oligomer treatment: an open-label, phase 2, dose-escalation study. Lancet 378:595\u2013605","journal-title":"Lancet"},{"issue":"437","key":"4_CR3","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.aan0713","volume":"10","author":"H Komaki","year":"2018","unstructured":"Komaki H et al (2018) Systemic administration of the antisense oligonucleotide NS-065\/NCNP-01 for skipping of exon 53 in patients with Duchenne muscular dystrophy. Sci Transl Med 10(437):eaan0713","journal-title":"Sci Transl Med"},{"key":"4_CR4","doi-asserted-by":"publisher","first-page":"3906","DOI":"10.1038\/s41467-018-06206-0","volume":"9","author":"L Antoury","year":"2018","unstructured":"Antoury L et al (2018) Analysis of extracellular mRNA in human urine reveals splice variant biomarkers of muscular dystrophies. Nat Commun 9:3906","journal-title":"Nat Commun"},{"key":"4_CR5","doi-asserted-by":"publisher","first-page":"3807","DOI":"10.1038\/s41598-019-40421-z","volume":"9","author":"H Takizawa","year":"2019","unstructured":"Takizawa H et al (2019) Modelling Duchenne muscular dystrophy in MYOD1-converted urine-derived cells treated with 3-deazaneplanocin a hydrochloride. Sci Rep 9:3807","journal-title":"Sci Rep"},{"issue":"1","key":"4_CR6","doi-asserted-by":"publisher","first-page":"2329","DOI":"10.1038\/s41598-024-52530-5","volume":"14","author":"K Kunitake","year":"2024","unstructured":"Kunitake K et al (2024) Characterization of CD90\/Thy-1 as a crucial molecular signature for myogenic differentiation in human urine-derived cells through single-cell RNA sequencing. Sci Rep 14(1):2329","journal-title":"Sci Rep"}],"container-title":["Methods in Molecular Biology","Splice Switching"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/978-1-0716-4738-7_4","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T07:58:42Z","timestamp":1778918322000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/978-1-0716-4738-7_4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,1]]},"ISBN":["9781071647370","9781071647387"],"references-count":6,"URL":"https:\/\/doi.org\/10.1007\/978-1-0716-4738-7_4","relation":{},"ISSN":["1064-3745","1940-6029"],"issn-type":[{"value":"1064-3745","type":"print"},{"value":"1940-6029","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,1]]},"assertion":[{"value":"1 October 2025","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}}]}}