{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,2]],"date-time":"2026-01-02T01:07:41Z","timestamp":1767316061060,"version":"3.48.0"},"publisher-location":"New York, NY","reference-count":18,"publisher":"Springer US","isbn-type":[{"value":"9781071650189","type":"print"},{"value":"9781071650196","type":"electronic"}],"license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026]]},"DOI":"10.1007\/978-1-0716-5019-6_5","type":"book-chapter","created":{"date-parts":[[2026,1,2]],"date-time":"2026-01-02T01:04:05Z","timestamp":1767315845000},"page":"67-74","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Infectious Models in Mice for Study of Gut Inflammation: Primary Cultures of Myenteric Neurons"],"prefix":"10.1007","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2074-1204","authenticated-orcid":false,"given":"Mayra Fernanda","family":"Ricci","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9272-5209","authenticated-orcid":false,"given":"Fabiana Sim\u00e3o","family":"Machado","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,1,2]]},"reference":[{"key":"5_CR1","doi-asserted-by":"publisher","DOI":"10.1017\/9781108778411","volume-title":"The integrative action of the autonomic nervous system","author":"W J\u00e4nig","year":"2006","unstructured":"J\u00e4nig W (2006) The integrative action of the autonomic nervous system. Neurobiology of Homeostasis, Cambridge. https:\/\/doi.org\/10.1017\/9781108778411"},{"key":"5_CR2","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1113\/expphysiol.2007.041178","volume":"93","author":"JA Armour","year":"2008","unstructured":"Armour JA (2008) Potential clinical relevance of the \u201clittle brain\u201d on the mammalian heart. Exp Physiol 93:165\u2013176. https:\/\/doi.org\/10.1113\/expphysiol.2007.041178","journal-title":"Exp Physiol"},{"key":"5_CR3","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1016\/0165-1838(81)90059-X","volume":"3","author":"WC de Groat","year":"1981","unstructured":"de Groat WC, Nadelhaft I, Milne RJ, Booth AM, Morgan C, Thor K (1981) Organization of the sacral parasympathetic reflex pathways to the urinary bladder and large intestine. J Auton Nerv Syst 3:135\u2013160. https:\/\/doi.org\/10.1016\/0165-1838(81)90059-X","journal-title":"J Auton Nerv Syst"},{"key":"5_CR4","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950x.1977.tb01640.x","volume-title":"Physiology of gastric motility and gastric emptying","author":"W Hasler","year":"2003","unstructured":"Hasler W (2003) Physiology of gastric motility and gastric emptying. Lippincott, Philadelphia. https:\/\/doi.org\/10.1111\/j.1532-950x.1977.tb01640.x"},{"key":"5_CR5","doi-asserted-by":"publisher","DOI":"10.1002\/9780470988756","volume-title":"The enteric nervous system","author":"J Furness","year":"2006","unstructured":"Furness J (2006) The enteric nervous system. Blackwell, Oxford. https:\/\/doi.org\/10.1002\/9780470988756"},{"key":"5_CR6","doi-asserted-by":"publisher","first-page":"1842","DOI":"10.1053\/j.gastro.2008.05.021","volume":"134","author":"ML Schubert","year":"2008","unstructured":"Schubert ML, Peura DA (2008) Control of gastric acid secretion in health and disease. Gastroenterology 134:1842\u20131860. https:\/\/doi.org\/10.1053\/j.gastro.2008.05.021","journal-title":"Gastroenterology"},{"key":"5_CR7","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1038\/s41577-019-0247-z","volume":"20","author":"JR Huh","year":"2020","unstructured":"Huh JR, Veiga-Fernandes H (2020) Neuroimmune circuits in inter-organ communication. Nat Rev Immunol 20:217\u2013228. https:\/\/doi.org\/10.1038\/s41577-019-0247-z","journal-title":"Nat Rev Immunol"},{"key":"5_CR8","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1056\/NEJM200007063430107","volume":"343","author":"PJ Delves","year":"2000","unstructured":"Delves PJ, Roitt IM (2000) The immune system. N Engl J Med 343:37\u201349. https:\/\/doi.org\/10.1056\/NEJM200007063430107","journal-title":"N Engl J Med"},{"key":"5_CR9","doi-asserted-by":"publisher","first-page":"1777","DOI":"10.1016\/S0140-6736(00)04904-7","volume":"357","author":"J Parkin","year":"2001","unstructured":"Parkin J, Cohen B (2001) An overview of the immune system. Lancet 357:1777\u20131789. https:\/\/doi.org\/10.1016\/S0140-6736(00)04904-7","journal-title":"Lancet"},{"key":"5_CR10","doi-asserted-by":"publisher","first-page":"298","DOI":"10.1038\/nature10208","volume":"474","author":"KJ Maloy","year":"2011","unstructured":"Maloy KJ, Powrie F (2011) Intestinal homeostasis and its breakdown in inflammatory bowel disease. Nature 474:298\u2013306. https:\/\/doi.org\/10.1038\/nature10208","journal-title":"Nature"},{"key":"5_CR11","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1016\/s0065-308x(08)60472-8","volume":"6","author":"F Koberle","year":"1968","unstructured":"Koberle F (1968) Chagas\u2019 disease and Chagas\u2019 syndromes: the pathology of American Trypanosomiasis. Adv Parasitol 6:63\u2013116. https:\/\/doi.org\/10.1016\/s0065-308x(08)60472-8","journal-title":"Adv Parasitol"},{"key":"5_CR12","doi-asserted-by":"publisher","first-page":"884","DOI":"10.1111\/j.1572-0241.1998.270_r.x","volume":"93","author":"RB De Oliveira","year":"1998","unstructured":"De Oliveira RB, Troncon LEA, Dantas RO, Meneghelli UG (1998) Gastrointestinal manifestations of Chagas\u2019 disease. Am J Gastroenterol 93:884\u2013889. https:\/\/doi.org\/10.1111\/j.1572-0241.1998.270_r.x","journal-title":"Am J Gastroenterol"},{"key":"5_CR13","doi-asserted-by":"publisher","first-page":"286","DOI":"10.1038\/nrgastro.2012.32","volume":"9","author":"J Furness","year":"2012","unstructured":"Furness J (2012) The enteric nervous system and neurogastroenterology. Nat Rev Gastroenterol Hepatol 9:286\u2013294. https:\/\/doi.org\/10.1038\/nrgastro.2012.32","journal-title":"Nat Rev Gastroenterol Hepatol"},{"key":"5_CR14","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1016\/j.schres.2012.02.025","volume":"138","author":"EG Severance","year":"2012","unstructured":"Severance EG, Alaedini A, Yang S et al (2012) Gastrointestinal inflammation and associated immune activation in schizophrenia. Schizophr Res 138:48\u201353. https:\/\/doi.org\/10.1016\/j.schres.2012.02.025","journal-title":"Schizophr Res"},{"key":"5_CR15","doi-asserted-by":"publisher","first-page":"230","DOI":"10.1111\/bdi.12159","volume":"16","author":"EG Severance","year":"2014","unstructured":"Severance EG, Gressitt KL, Yang S, Stallings CR, Origoni AE, Vaughan C, Khushalani S, Alaedini A, Dickerson FB, Yolken RH (2014) Seroreactive marker for inflammatory bowel disease and associations with antibodies to dietary proteins in bipolar disorder. Bipolar Disord 16:230\u2013240. https:\/\/doi.org\/10.1111\/bdi.12159","journal-title":"Bipolar Disord"},{"key":"5_CR16","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1016\/S0006-8993(00)02867-5","volume":"883","author":"T Takahashi","year":"2000","unstructured":"Takahashi T, Qoubaitary A, Owyang C, Wiley JW (2000) Decreased expression of nitric oxide synthase in the colonic myenteric plexus of aged rats. Brain Res 883:15\u201321. https:\/\/doi.org\/10.1016\/S0006-8993(00)02867-5","journal-title":"Brain Res"},{"key":"5_CR17","doi-asserted-by":"publisher","first-page":"G896","DOI":"10.1152\/ajpgi.00259.2009","volume":"298","author":"A-M Pelletier","year":"2010","unstructured":"Pelletier A-M, Venkataramana S, Miller KG, Bennett BM, Nair DG, Lourenssen S, Blennerhassett MG (2010) Neuronal nitric oxide inhibits intestinal smooth muscle growth. Am J Physiol Gastrointest Liver Physiol 298:G896\u2013G907. https:\/\/doi.org\/10.1152\/ajpgi.00259.2009","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"5_CR18","doi-asserted-by":"publisher","first-page":"73","DOI":"10.3389\/fncel.2016.00073","volume":"10","author":"RK Bubenheimer","year":"2016","unstructured":"Bubenheimer RK, Brown IAM, Fried DE, McClain JL, Gulbransen BD (2016) Sirtuin-3 is expressed by enteric neurons but it does not play a major role in their regulation of oxidative stress. Front Cell Neurosci 10:73. https:\/\/doi.org\/10.3389\/fncel.2016.00073","journal-title":"Front Cell Neurosci"}],"container-title":["Methods in Molecular Biology","Models in Inflammation and Immunopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/978-1-0716-5019-6_5","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,2]],"date-time":"2026-01-02T01:04:05Z","timestamp":1767315845000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/978-1-0716-5019-6_5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"ISBN":["9781071650189","9781071650196"],"references-count":18,"URL":"https:\/\/doi.org\/10.1007\/978-1-0716-5019-6_5","relation":{},"ISSN":["1064-3745","1940-6029"],"issn-type":[{"value":"1064-3745","type":"print"},{"value":"1940-6029","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]},"assertion":[{"value":"2 January 2026","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}}]}}