{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T23:07:52Z","timestamp":1778713672452,"version":"3.51.4"},"publisher-location":"New York, NY","reference-count":20,"publisher":"Springer US","isbn-type":[{"value":"9781071652992","type":"print"},{"value":"9781071653005","type":"electronic"}],"license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026]]},"DOI":"10.1007\/978-1-0716-5300-5_6","type":"book-chapter","created":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T22:12:47Z","timestamp":1778710367000},"page":"49-59","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Mild Strain Cross-Protection in Passion Fruit"],"prefix":"10.1007","author":[{"given":"Linxi","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongguang","family":"Cui","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhaoji","family":"Dai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,5,1]]},"reference":[{"key":"6_CR1","doi-asserted-by":"publisher","first-page":"592","DOI":"10.1094\/PD-73-0592A","volume":"73","author":"D Gonsalves","year":"1989","unstructured":"Gonsalves D, Garnsey SM (1989) Cross-protection techniques for control of plant virus diseases in the tropics. Plant Dis 73:592\u2013597","journal-title":"Plant Dis"},{"key":"6_CR2","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1016\/S0065-3527(10)76006-1","volume":"76","author":"H Ziebell","year":"2010","unstructured":"Ziebell H, Carr JP (2010) Cross-protection: a century of mystery. Adv Virus Res 76:211\u2013264","journal-title":"Adv Virus Res"},{"key":"6_CR3","first-page":"577","volume":"39","author":"HH McKinney","year":"1929","unstructured":"McKinney HH (1929) Mosaic diseases in the Canary Islands, West Africa and Gibraltar. J Agric Res 39:577\u2013578","journal-title":"J Agric Res"},{"key":"6_CR4","doi-asserted-by":"publisher","first-page":"76","DOI":"10.3389\/fmicb.2013.00076","volume":"4","author":"SY Folimonova","year":"2013","unstructured":"Folimonova SY (2013) Developing an understanding of cross-protection by citrus tristeza virus. Front Microbiol 4:76","journal-title":"Front Microbiol"},{"key":"6_CR5","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1094\/PHYTO-01-14-0018-R","volume":"105","author":"GM Chewachong","year":"2015","unstructured":"Chewachong GM, Miller SA, Blakeslee JJ et al (2015) Generation of an attenuated, cross-protective Pepino mosaic virus variant through alignment-guided mutagenesis of the viral capsid protein. Phytopathology 105:126\u2013134","journal-title":"Phytopathology"},{"key":"6_CR6","doi-asserted-by":"publisher","first-page":"1757","DOI":"10.1094\/PDIS-05-22-1130-RE","volume":"107","author":"HW Cheng","year":"2023","unstructured":"Cheng HW, Lin TT, Huang CH et al (2023) Modification of papaya ringspot virus HC-pro to generate effective attenuated mutants for overcoming the problem of strain-specific cross protection. Plant Dis 107:1757\u20131768","journal-title":"Plant Dis"},{"key":"6_CR7","doi-asserted-by":"publisher","first-page":"882","DOI":"10.1094\/PD-77-0882","volume":"77","author":"Y Kosaka","year":"1993","unstructured":"Kosaka Y, Fukunishi T (1993) Attenuated isolates of soybean mosaic virus derived at a low temperature. Plant Dis 77:882\u2013886","journal-title":"Plant Dis"},{"key":"6_CR8","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1094\/PHYTO-97-3-0287","volume":"97","author":"SS Lin","year":"2007","unstructured":"Lin SS, Wu HW, Jan FJ et al (2007) Modifications of the helper component-protease of zucchini yellow mosaic virus for generation of attenuated mutants for cross protection against severe infection. Phytopathology 97:287\u2013296","journal-title":"Phytopathology"},{"key":"6_CR9","doi-asserted-by":"publisher","first-page":"947","DOI":"10.1111\/mpp.13201","volume":"23","author":"JAJ Raja","year":"2022","unstructured":"Raja JAJ, Huang CH, Chen CC et al (2022) Modification of N-terminal FWKG-\u03b1H1 element of potyviral HC-Pro affects its multiple functions and generates effective attenuated mutants for cross protection. Mol Plant Pathol 23:947\u2013965","journal-title":"Mol Plant Pathol"},{"key":"6_CR10","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1094\/PHYTO-09-19-0328-R","volume":"110","author":"D Tuo","year":"2020","unstructured":"Tuo D, Zhou P, Zhao G et al (2020) A double mutation in the conserved motifs of the helper component protease of papaya leaf distortion mosaic virus for the generation of a cross-protective attenuated strain. Phytopathology 110:187\u2013193","journal-title":"Phytopathology"},{"key":"6_CR11","doi-asserted-by":"publisher","first-page":"5256","DOI":"10.1002\/ps.8252","volume":"80","author":"L Wang","year":"2024","unstructured":"Wang L, Shi W, Aziz A et al (2024) Mutating the arginine residue within the FRNK motif of telosma mosaic virus (TelMV) HC-Pro protein attenuates viral infection and confers effective protection against TelMV in passion fruit (Passiflora edulis). Pest Manag Sci 80:5256\u20135265","journal-title":"Pest Manag Sci"},{"key":"6_CR12","doi-asserted-by":"publisher","first-page":"839","DOI":"10.3390\/biology13100839","volume":"13","author":"W Wu","year":"2024","unstructured":"Wu W, Ma F, Zhang X et al (2024) Research progress on viruses of Passiflora edulis. Biology 13:839","journal-title":"Biology"},{"key":"6_CR13","doi-asserted-by":"publisher","first-page":"242","DOI":"10.1111\/ppa.13811","volume":"73","author":"C Zhang","year":"2024","unstructured":"Zhang C, Jiang J, Chen S et al (2024) Telosma mosaic virus: an emerging plant RNA virus causing production loss in passion fruit across Asia. Plant Pathol 73:242\u2013249","journal-title":"Plant Pathol"},{"key":"6_CR14","doi-asserted-by":"publisher","first-page":"2583","DOI":"10.1007\/s00705-018-3885-8","volume":"163","author":"K Yang","year":"2018","unstructured":"Yang K, Yan H, Song L et al (2018) Analysis of the complete genome sequence of a potyvirus from passion fruit suggests its taxonomic classification as a member of a new species. Arch Virol 163:2583\u20132586","journal-title":"Arch Virol"},{"key":"6_CR15","doi-asserted-by":"publisher","first-page":"744","DOI":"10.1111\/mpp.12553","volume":"19","author":"AA Valli","year":"2018","unstructured":"Valli AA, Gallo A, Rodamilans B et al (2018) The HCPro from the Potyviridae family: an enviable multitasking helper component that every virus would like to have. Mol Plant Pathol 19:744\u2013763","journal-title":"Mol Plant Pathol"},{"key":"6_CR16","doi-asserted-by":"publisher","first-page":"13135","DOI":"10.1128\/JVI.01031-07","volume":"81","author":"YM Shiboleth","year":"2007","unstructured":"Shiboleth YM, Haronsky E, Leibman D et al (2007) The conserved FRNK box in HC-Pro, a plant viral suppressor of gene silencing, is required for small RNA binding and mediates symptom development. J Virol 81:13135\u201313148","journal-title":"J Virol"},{"key":"6_CR17","doi-asserted-by":"publisher","first-page":"944","DOI":"10.1094\/MPMI-04-14-0116-R","volume":"27","author":"YJ Kung","year":"2014","unstructured":"Kung YJ, Lin PC, Yeh SD et al (2014) Genetic analyses of the FRNK motif function of Turnip mosaic virus uncover multiple and potentially interactive pathways of cross-protection. Mol Plant-Microbe Interact 27:944\u2013955","journal-title":"Mol Plant-Microbe Interact"},{"key":"6_CR18","doi-asserted-by":"publisher","first-page":"467","DOI":"10.1094\/PHYTO.2000.90.5.467","volume":"90","author":"A Gal-On","year":"2000","unstructured":"Gal-On A (2000) A point mutation in the FRNK motif of the potyvirus helper component-protease gene alters symptom expression in cucurbits and elicits protection against the severe homologous virus. Phytopathology 90:467\u2013473","journal-title":"Phytopathology"},{"key":"6_CR19","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2020.01279","volume":"11","author":"XJ Xu","year":"2020","unstructured":"Xu XJ, Li HG, Cheng DJ et al (2020) A spontaneous complementary mutation restores the RNA silencing suppression activity of HC-pro and the virulence of sugarcane mosaic virus. Front Plant Sci 11:549767","journal-title":"Front Plant Sci"},{"key":"6_CR20","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.01444-22","volume":"97","author":"B Gou","year":"2023","unstructured":"Gou B, Dai Z, Qin L et al (2023) A zinc finger motifin the P1 N terminus, highly conserved in a subset of potyviruses, is associated with the host range and fitness of Telosma mosaic virus. J Virol 97:e0144422","journal-title":"J Virol"}],"container-title":["Methods in Molecular Biology","Plant Antiviral Resistance"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/978-1-0716-5300-5_6","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T22:12:48Z","timestamp":1778710368000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/978-1-0716-5300-5_6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"ISBN":["9781071652992","9781071653005"],"references-count":20,"URL":"https:\/\/doi.org\/10.1007\/978-1-0716-5300-5_6","relation":{},"ISSN":["1064-3745","1940-6029"],"issn-type":[{"value":"1064-3745","type":"print"},{"value":"1940-6029","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]},"assertion":[{"value":"1 May 2026","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}}]}}