{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,11]],"date-time":"2026-11-11T19:05:21Z","timestamp":1794423921383,"version":"4.9.1"},"publisher-location":"New York, NY","reference-count":82,"publisher":"Springer New York","isbn-type":[{"value":"9781468494815","type":"print"},{"value":"9781461301431","type":"electronic"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2001]]},"DOI":"10.1007\/978-1-4613-0143-1_1","type":"book-chapter","created":{"date-parts":[[2012,6,18]],"date-time":"2012-06-18T05:14:33Z","timestamp":1339996473000},"page":"1-42","source":"Crossref","is-referenced-by-count":5,"title":["Mammalian Toxicity of 1,3-Dichloropropene"],"prefix":"10.1007","author":[{"given":"William T.","family":"Stott","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B. Bhaskar","family":"Gollapudi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K. S.","family":"Rao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"1_CR1","first-page":"949","volume":"35","author":"I Berenblum","year":"1978","unstructured":"Berenblum I (1978) Established principles and unresolved problems in carcinogenesis. J Natl Cancer Inst 35:949.","journal-title":"J Natl Cancer Inst"},{"key":"1_CR2","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1016\/0272-0590(89)90068-7","volume":"12","author":"WJ Breslin","year":"1989","unstructured":"Breslin WJ, Kirk HD, Streeter CM, Quast JF, Szabo JR (1989) 1,3-Dichloropropene: two-generation inhalation reproduction study in Fischer 344 rats. Fundam Appl Toxicol 12:129\u2013143.","journal-title":"Fundam Appl Toxicol"},{"key":"1_CR3","first-page":"167","volume":"48","author":"EJ Brouwer","year":"1991","unstructured":"Brouwer EJ, Evelo CTA, Verplanke AJW, van Welie RTH, Wolff FA (1991) Biological effect monitoring of occupational expolsure to 1,3-dichloropropene: effects on liver and reanl function and on glutathione conjugation. Br J Ind Med 48:167\u2013172.","journal-title":"Br J Ind Med"},{"key":"1_CR4","doi-asserted-by":"publisher","first-page":"713","DOI":"10.1016\/0272-0590(89)90003-1","volume":"12","author":"JV Bruckner","year":"1989","unstructured":"Bruckner JV, MacKenzie WF, Ramanathan R, Muralidhara S, Kim HJ, Dallas CE (1989) Oral toxicity of 1,2-dichloropropene: acute, short-term and long-term studies in rats. Fundam Appl Toxicol 12:713\u2013730.","journal-title":"Fundam Appl Toxicol"},{"key":"1_CR5","volume-title":"Chemically Induced Cell Proliferation: Implications for Risk Assessment","author":"BE Butterworth","year":"1991","unstructured":"Butterworth BE, Slaga TJ, Farland W, McClain M (1991) Chemically Induced Cell Proliferation: Implications for Risk Assessment. Wiley-Liss, New York."},{"key":"1_CR6","doi-asserted-by":"publisher","first-page":"149","DOI":"10.3109\/00498257909038715","volume":"9","author":"I Climie","year":"1979","unstructured":"Climie I, Hutson D, Morrison B, Stoydin G (1979) Glutathione conjugation in the detoxi-cation of (Z)-l,3-dichloropropene (a component of the nematocide D-D) in the rat. Xenobiotica 9:149\u2013156.","journal-title":"Xenobiotica"},{"key":"1_CR7","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1016\/0009-2797(84)90130-3","volume":"50","author":"C Creedy","year":"1984","unstructured":"Creedy C, Brooks T, Dean B, Hutson D, Wright A (1984) The protective action of glutathione on the microbial mutagenicity of the Z- and E-isomers of 1,3-dichloropro-pene. Chem-Biol Interact 50:39\u201348.","journal-title":"Chem-Biol Interact"},{"key":"1_CR8","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/0165-1110(85)90005-3","volume":"153","author":"BJ Dean","year":"1985","unstructured":"Dean BJ, Brooks TM, Hodson-Walker G, Hutson DH (1985) Genetic toxicology testing of industrial chemicals. Mutat Res 153:57\u201377.","journal-title":"Mutat Res"},{"key":"1_CR9","first-page":"1915","volume":"37","author":"F Lorenzo De","year":"1977","unstructured":"De Lorenzo F, Degtinnocenti S, Ruocco A, Silengo L, Cortese R (1977) Mutagenicity of pesticides containing 1,3-dichloropropene. Cancer Res 37:1915\u20131917.","journal-title":"Cancer Res"},{"key":"1_CR10","first-page":"A585","volume":"4","author":"F Dietz","year":"1984","unstructured":"Dietz F, Hermann E, Ramsey J (1984a) The pharmacokinetics of l4C-1,3-dichloropro-peneichloropropene in rats and mice following oral administration. Toxicologist 4: A585.","journal-title":"Toxicologist"},{"key":"1_CR11","first-page":"A586","volume":"4","author":"F Dietz","year":"1984","unstructured":"Dietz F, Dittenber D, Kirk H, Ramsey J (1984b) Non-protein sulfhydryl content and macromolecular binding in rats and mice following administration of 1,3-dichloropro-peneichloropropene. Toxicologist 4:A586.","journal-title":"Toxicologist"},{"key":"1_CR12","doi-asserted-by":"publisher","first-page":"370","DOI":"10.1007\/978-3-642-73113-6_67","volume":"12","author":"A Nucci Di","year":"1988","unstructured":"Di Nucci A, Imbriani M, Ghittori S, Baldi C, Locatelli C, Manzo L, Capodaglio E (1988) 1,2-Dichloropropene-induced liver toxicity. Clinical data and preliminary studies in rats. The target organ and the toxic process. Arch Toxicol 12(suppl):370\u2013374.","journal-title":"Arch Toxicol"},{"key":"1_CR13","doi-asserted-by":"publisher","first-page":"831","DOI":"10.3109\/00498258209038955","volume":"12","author":"E Eder","year":"1982","unstructured":"Eder E, Henschler D, Neudecker T (1982a) Mutagenic properties of allylic and \u03b1,\u03b2-unsaturated compounds: Consideration of alkylating mechanisms. Xenobiotica 12: 831\u2013848.","journal-title":"Xenobiotica"},{"key":"1_CR14","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1016\/0009-2797(82)90060-6","volume":"38","author":"E Eder","year":"1982","unstructured":"Eder E, Neudecker T, Lutz D, Henschler D (1982b) Correlation of alkylating and mutagenic activities of allyl and allylic compounds: standard alkylation test vs. kinetic investigation. Chem-Biol Interact 38:303\u2013315.","journal-title":"Chem-Biol Interact"},{"key":"1_CR15","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1002\/em.2850240307","volume":"24","author":"MC Elia","year":"1994","unstructured":"Elia MC, Storer RD, McKelvey TW, Kraynak AR, Barnum JE, Harmon LS, DeLuca JG, Nichols WW (1994) Rapid DNA degradation in primary rat hepatocytes treated with diverse cytotoxic chemicals: analysis by pulsed field gel electrophoresis and implications for alkaline elution assay. Environ Mol Mutagen 24:181\u2013191.","journal-title":"Environ Mol Mutagen"},{"key":"1_CR16","first-page":"71","volume-title":"Pathology of Fischer Rat. Reference and Atlas","author":"SL Eustis","year":"1990","unstructured":"Eustis SL, Boorman GA, Harada T, Popp JA (1990) Liver. In: Boorman GA, Eustis SL, Elwll MR, Montgomery CA Jr, Mckenzie WF, (eds) Pathology of Fischer Rat. Reference and Atlas. Academic Press, San Diego, pp 71\u201394."},{"key":"1_CR17","doi-asserted-by":"publisher","first-page":"300","DOI":"10.1016\/0272-0590(88)90155-8","volume":"11","author":"GD Fisher","year":"1988","unstructured":"Fisher GD, Kilgore WW (1988a) Mercapturic acid excretion by rats following inhalation exposure to 1,3-dichloropropene. Fundam Appl Toxicol 11:300\u2013307.","journal-title":"Fundam Appl Toxicol"},{"key":"1_CR18","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1080\/15287398809531104","volume":"23","author":"GD Fisher","year":"1988","unstructured":"Fisher GD, Kilgore WW (1988b) Tissue levels of glutathione following acute inhalation of 1,3-dichloropropene. J Toxicol Environ Health 23:171\u2013182.","journal-title":"J Toxicol Environ Health"},{"key":"1_CR19","doi-asserted-by":"publisher","first-page":"269","DOI":"10.3109\/00498258909042272","volume":"19","author":"GD Fisher","year":"1989","unstructured":"Fisher GD, Kilgore WW (1989) Pharmacokinetics of S-[3-chloroprop-2-enyl]glutathione in rats following acute inhalation exposure to 1,3-dichloropropene. Xenobiotica 19: 269\u2013278.","journal-title":"Xenobiotica"},{"key":"1_CR20","first-page":"50","volume":"27","author":"P Flessel","year":"1978","unstructured":"Flessel P, Goldsmith J, Kahn E, Wesolwski J, Maddy K, Peoples S (1978) Acute and possible long-term effects of 1,3-dichloropropene\u2014California. MMWR (Morb Mortal Week Rep) 27:50\u201355.","journal-title":"MMWR (Morb Mortal Week Rep)"},{"key":"1_CR21","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1006\/taap.1993.1094","volume":"120","author":"M Ghia","year":"1993","unstructured":"Ghia M, Robbiano L, Allavena A, Martelli A, Brambilla G (1993) Genotoxic activity of 1,3-dichloropropene in a battery of in vivo short-term tests. Toxicol Appl Pharmacol 120:120\u2013125.","journal-title":"Toxicol Appl Pharmacol"},{"key":"1_CR22","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1002\/(SICI)1098-2280(1998)32:4<351::AID-EM9>3.0.CO;2-M","volume":"32","author":"BB Gollapudi","year":"1998","unstructured":"Gollapudi BB, Cieszlak FS, Day SJ, Carney EW (1998) Dominant lethal test with rats exposed to 1,3-dichloropropene by inhalation. Environ Mol Mutagen 32:351\u2013359.","journal-title":"Environ Mol Mutagen"},{"key":"1_CR23","first-page":"119","volume-title":"Clinical Toxicology of Commercial Products","author":"R Gosselin","year":"1976","unstructured":"Gosselin R, Hodge H, Smith R, Gleason M (1976) Clinical Toxicology of Commercial Products, 4th Ed. Williams & Wilkins, Baltimore, pp 119\u2013121.","edition":"4"},{"key":"1_CR24","doi-asserted-by":"publisher","first-page":"562","DOI":"10.1016\/0272-0590(87)90141-2","volume":"8","author":"TR Hanley","year":"1987","unstructured":"Hanley TR, John-Greene J, Young JT, Calhoun LL, Rao KS (1987) Evaluation of the effects of inhalation exposure to 1,3-dichloropropene on fetal development in rats and rabbits. Fundam Appl Toxicol 8:562\u2013570.","journal-title":"Fundam Appl Toxicol"},{"key":"1_CR25","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1006\/faat.1996.0125","volume":"32","author":"KT Haut","year":"1996","unstructured":"Haut KT, Stebbins KE, Johnson KE, Shabrang SN, Stott WT (1996) Subchronic toxicity of ingested 1,3-dichloropropene in rats and mice. Fundam Appl Toxicol 32:224\u2013232.","journal-title":"Fundam Appl Toxicol"},{"key":"1_CR26","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1177\/096032719401300502","volume":"13","author":"AF Hernandez","year":"1994","unstructured":"Hernandez AF, Martin-Rubi JC, Ballesteros JL, Oliver M, Pia A, Villanueva E (1994) Clinical and pathological findings in fatal 1,3-dichloropropene intoxication. Hum Exp Toxicol 13:303\u2013306.","journal-title":"Hum Exp Toxicol"},{"key":"1_CR27","doi-asserted-by":"publisher","first-page":"677","DOI":"10.1016\/0015-6264(71)90157-X","volume":"9","author":"DH Hutson","year":"1971","unstructured":"Hutson DH, Moss JA, Pickering BA (1971) Components of the soil fumigant D-D* and their metabolites in the rat. Food Cosmet Toxicol 9:677\u2013680.","journal-title":"Food Cosmet Toxicol"},{"key":"1_CR28","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1016\/S0378-4274(96)03779-4","volume":"89","author":"S Kevekordes","year":"1996","unstructured":"Kevekordes S, Gebel T, Pav K, Edenharder R, Dunkelberg H (1996) Genotoxicity of selected pesticides in the mouse bone marrow micronucleus test and in the sister-chromatid exchange test with human lymphocytes in vitro. Toxicol Lett 89:35\u201342.","journal-title":"Toxicol Lett"},{"key":"1_CR29","doi-asserted-by":"publisher","first-page":"396","DOI":"10.1177\/096032719601500506","volume":"15","author":"S Kezic","year":"1996","unstructured":"Kezic S, Monster AC, Verplanke JW, de Wolff FA (1996) Dermal absorption of cis-1,3-dichloropropene vapour: human experimental exposure. Hum Exp Toxicol 15: 396\u2013399.","journal-title":"Hum Exp Toxicol"},{"key":"1_CR30","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1016\/0300-483X(94)90109-0","volume":"88","author":"KT Kitchin","year":"1994","unstructured":"Kitchin KT, Brown JL (1994) Dose-response relationship for rat liver DNA damage caused by 49 rodent carcinogens. Toxicology 88:31\u201349.","journal-title":"Toxicology"},{"key":"1_CR31","doi-asserted-by":"publisher","first-page":"214","DOI":"10.1016\/0272-0590(88)90305-3","volume":"10","author":"SL Linnett","year":"1988","unstructured":"Linnett SL, Clark DG, Blair D, Cassidy SL (1988) Effects of subchronic inhalation of D-D(l,3-dichloropropene\/l,2-dichloropropane) on reproduction in male and female rats. Fundam Appl Toxicol 10:214\u2013223.","journal-title":"Fundam Appl Toxicol"},{"key":"1_CR32","doi-asserted-by":"publisher","first-page":"23","DOI":"10.3109\/10408448809040816","volume":"19","author":"EA Lock","year":"1988","unstructured":"Lock EA (1988) Studies on the mechanism of nephrotoxicity and nephrocarcinogenicity of halogenated alkenes. Crit Rev Toxicol 19:23\u201342.","journal-title":"Crit Rev Toxicol"},{"key":"1_CR33","doi-asserted-by":"publisher","first-page":"418","DOI":"10.1016\/0272-0590(89)90016-X","volume":"12","author":"LG Lomax","year":"1989","unstructured":"Lomax LG, Stott WT, Johnson KA, Calhoun LL, Yano BL, Quast JF (1989) The chronic toxicity and oncogenicity of inhaled technical grade 1,3-dichloropropene in rats and mice. Fundam Appl Toxicol 12:418\u2013431.","journal-title":"Fundam Appl Toxicol"},{"key":"1_CR34","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1002\/em.2850130108","volume":"3","author":"KS Loveday","year":"1989","unstructured":"Loveday KS, Lugo MH, Resnick MA, Anderson BE, Zeiger E (1989) Chromosome aberration and sister chromatid exchange tests in Chinese hamster ovary cells in vitro: II. Results with 20 chemicals. Environ Mol Mutagen 3:60\u201394.","journal-title":"Environ Mol Mutagen"},{"key":"1_CR35","doi-asserted-by":"publisher","first-page":"1409","DOI":"10.1001\/archinte.1984.00350190097018","volume":"144","author":"A Markovitz","year":"1984","unstructured":"Markovitz A, Crosby WH (1984) Chemical carcinogenesis. A soil fumigant, 1,3-dichloropropene, as possible cause of hematologic malignancies. Arch Intern Med 144: 1409\u20131411.","journal-title":"Arch Intern Med"},{"key":"1_CR36","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1006\/taap.1993.1093","volume":"120","author":"A Martelli","year":"1993","unstructured":"Martelli A, Allavena A, Ghia M, Robbiano L, Brambilla G (1993) Cytotoxic and geno-toxic activity of 1,3-dichlororporpene in cultured mammalian cells. Toxicol Appl Pharmacol 120:114\u2013119.","journal-title":"Toxicol Appl Pharmacol"},{"key":"1_CR37","first-page":"665","volume":"54","author":"J Meulenbelt","year":"1997","unstructured":"Meulenbelt J, de Vries I (1997) Acute work-related poisoning by pesticides in the Netherlands: a one year follow-up study. Przegl Lek 54:665\u2013669.","journal-title":"Przegl Lek"},{"key":"1_CR38","doi-asserted-by":"publisher","first-page":"419","DOI":"10.1584\/jpestics.15.419","volume":"15","author":"T Miyaoka","year":"1990","unstructured":"Miyaoka T, Yamashita E, Hasegawa T, Akiyama M, Tsuda S, Shirasu Y (1990) Mechanism of 1,3-dichloropropene-induced hepatotoxicity in mice. J Pestic Sci 15:419\u2013425.","journal-title":"J Pestic Sci"},{"key":"1_CR39","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1002\/em.2850180109","volume":"18","author":"BC Myhr","year":"1991","unstructured":"Myhr BC, Caspary WJ (1991) Chemical mutagenesis at the thymidine kinase locus in L5178Y mouse lymphoma cells: results for 31 coded compounds in the National Toxicology Program. Environ Mol Mutagen 18:51\u201383.","journal-title":"Environ Mol Mutagen"},{"key":"1_CR40","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1111\/j.1600-0536.1976.tb03031.x","volume":"2","author":"JP Nater","year":"1976","unstructured":"Nater JP, Goskens VHJ (1976) Occupational dermatosis due to a soil fumigant. Contact Dermatitis 2:227\u2013229.","journal-title":"Contact Dermatitis"},{"key":"1_CR41","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/0165-1218(86)90076-5","volume":"170","author":"T Neudecker","year":"1986","unstructured":"Neudecker T, Henschler D (1986) Mutagenicity of chloroolefins in the Salmonella\/mammalian microsome test. III. Metabolic activation of the allylic chloropropenes allyl chloride, 1,3-dichloropropene, 2,3-dichloro-l-propene, 1,2,3-trichloropropene, 1,1,2,3-tetrachloro-2-propene and hexachloropropene by S9 mix via two different metabolic pathways. Mutat Res 170:1\u20139.","journal-title":"Mutat Res"},{"key":"1_CR42","doi-asserted-by":"publisher","first-page":"1084","DOI":"10.1007\/BF01945985","volume":"33","author":"T Neudecker","year":"1977","unstructured":"Neudecker T, Stefani A, Henschler D (1977) In vitro mutagenicity of soil nematocide 1,3-dichloropropene. Experientia (Basel) 33:1084\u20131085.","journal-title":"Experientia (Basel)"},{"key":"1_CR43","doi-asserted-by":"publisher","first-page":"2611","DOI":"10.1016\/0006-2952(80)90075-1","volume":"29","author":"T Neudecker","year":"1980","unstructured":"Neudecker T, Lutz D, Eder E, Henschler D (1980) Structure-activity relationship in halogen and alkyl substituted allyl and allylic compounds: correlation of alkating and mutagenic properties. Biochem Pharmacol 29:2611\u20132617.","journal-title":"Biochem Pharmacol"},{"key":"1_CR44","volume-title":"Carcinogenesis studies of TELONE II in F344\/N rats and B6C3F1 mice (gavage studies)","author":"NTP (National Toxicology Program)","year":"1985","unstructured":"NTP (National Toxicology Program) (1985) Carcinogenesis studies of TELONE II in F344\/N rats and B6C3F1 mice (gavage studies). Technical Rep 269, National Toxicology Program, Washington, DC."},{"key":"1_CR45","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1007\/BF00290544","volume":"59","author":"W Onkenhout","year":"1986","unstructured":"Onkenhout W, Mulder PPJ, Boogaard PJ, Buijs W, Vermeulen PE (1986) Identification and quantitative determination of mercapturic acids formed from Z-and E-1,3-dichloropropene by the rat, using gas chromatography with three different detection techniques. Arch Toxicol 59:235\u2013241.","journal-title":"Arch Toxicol"},{"key":"1_CR46","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1006\/enrs.1993.1138","volume":"63","author":"JD Osterloh","year":"1993","unstructured":"Osterloh JD, Feldman BJ (1993) Urinary protein markers in pesticide applicators during a chlorinated hydrocarbon exposure. Environ Res 63:171\u2013181.","journal-title":"Environ Res"},{"key":"1_CR47","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1080\/15287399009531388","volume":"28","author":"JD Osterloh","year":"1990","unstructured":"Osterloh JD, Xiwen H (1990) Effects of 1,3-dichloropropene on the kidney of Fisher 344 rats after pretreatment with diethylmaleate, buthionine sulfoximine, and amino-oxyacetic acid. J Toxicol Environ Health 28:247\u2013255.","journal-title":"J Toxicol Environ Health"},{"key":"1_CR48","doi-asserted-by":"publisher","first-page":"407","DOI":"10.1016\/0165-1218(83)90079-4","volume":"116","author":"J Osterloh","year":"1983","unstructured":"Osterloh J, Letz G, Pond S, Becker C (1983) An assessment of the potential testicular toxicity of 10 pesticides using the mouse-sperm morphology assay. Mutat Res 116: 407\u2013415.","journal-title":"Mutat Res"},{"key":"1_CR49","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1080\/00039896.1984.10545848","volume":"39","author":"JD Osterloh","year":"1984","unstructured":"Osterloh JD, Cohen BS, Popendorf W, Pond SM (1984) Urinary excretion of the N-acetyl cysteine conjugate of cis-1,3-dichloropropene by exposed individuals. Arch Environ Health 39:271\u2013275.","journal-title":"Arch Environ Health"},{"key":"1_CR50","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1080\/00039896.1989.9935885","volume":"44","author":"JD Osterloh","year":"1989","unstructured":"Osterloh JD, Wang R, Schneider F, Maddy K (1989) Biological monitoring of dichloro-propene: air concentrations, urinary metabolite and renal enzyme excretion. Arch Environ Health 44:207\u2013213.","journal-title":"Arch Environ Health"},{"key":"1_CR51","doi-asserted-by":"publisher","first-page":"899","DOI":"10.1080\/15287398209530212","volume":"9","author":"CM Parker","year":"1982","unstructured":"Parker CM, Coate WB, Voelker RW (1982) Subchronic inhalation toxicity of 1,3-di-chloropropene\/1,2-dichloropropane (D-D) in mice and rats. J Toxicol Environ Health 9:899\u2013910.","journal-title":"J Toxicol Environ Health"},{"key":"1_CR52","volume-title":"1,3-Dichloro-propene: in vitro cytogenetics test","author":"YF Sasaki","year":"1988","unstructured":"Sasaki YF, Imanishi H, Matsumoto K, Watanabe M, Watanabe K (1988) 1,3-Dichloro-propene: in vitro cytogenetics test. Institute of Environmental Toxicology, Kodaira, Tokyo."},{"key":"1_CR53","doi-asserted-by":"publisher","first-page":"1137","DOI":"10.1021\/tx980126y","volume":"11","author":"M Schneider","year":"1998","unstructured":"Schneider M, Quistad GB, Casida JE (1998a) 1,3-Dichloropropene epoxides: intermediates in bioactivation of the promutagen 1,3-dichloropropene. Chem Res Toxicol 11: 1137\u20131144.","journal-title":"Chem Res Toxicol"},{"key":"1_CR54","doi-asserted-by":"publisher","first-page":"1536","DOI":"10.1021\/tx9801256","volume":"11","author":"M Schneider","year":"1998","unstructured":"Schneider M, Quistad G, Casida JE (1998b) N2,7-bis(l-hydroxy-2-oxopropyl)-2\u2019-deoxy-guanosine: identical noncyclic adducts with 1,3-dichloropropene epoxides and meth-ylglyoxal. Chem Res Toxicol 11:1536\u20131542.","journal-title":"Chem Res Toxicol"},{"key":"1_CR55","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1002\/em.2850210210","volume":"21","author":"MD Shelby","year":"1993","unstructured":"Shelby MD, Erexson GL, Hook GJ, Tice RR (1993) Evaluation of a three-exposure mouse bone marrow micronucleus protocol: results with 49 chemicals. Environ Mol Mutagen 21:160\u2013179.","journal-title":"Environ Mol Mutagen"},{"key":"1_CR56","first-page":"331","volume":"21\u201327","author":"Y Shirasu","year":"1981","unstructured":"Shirasu Y, Moriya M, Tequka H, Teramoto S, Ohata T, Inoue T (1981) Mutagenicity Screening Studies on Pesticides. In, Environmental Mutagens and Carcinogens: Proc Third International Conference on Environmental Mutagens, Tokyo, Mishima, and Kyoto, September 21\u201327, pp 331\u2013335.","journal-title":"September"},{"key":"1_CR57","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1006\/rtph.1999.1352","volume":"30","author":"KE Stebbins","year":"1999","unstructured":"Stebbins KE, Quast JF, Haut KT, Stott WT (1999) Subchronic and chronic toxicity of ingested 1,3-dichloropropene in dogs. Regul Pharmacol Toxicol 30:233\u2013243.","journal-title":"Regul Pharmacol Toxicol"},{"key":"1_CR58","doi-asserted-by":"crossref","unstructured":"Stebbins KE, Johnson KA, Jeffries TK, Redmond JM, Haut KT, Shabrang SN, Stott WT (2000) Chronic toxicity and oncogenicity studies of ingested 1,3-dichloropropene in rats and mice. Regul Pharmacol Toxicol (in press).","DOI":"10.1006\/rtph.2000.1398"},{"key":"1_CR59","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1002\/em.2860020109","volume":"2","author":"SJ Stolzenberg","year":"1980","unstructured":"Stolzenberg SJ, Hine CH (1980) Mutagenicity of 2-and 3-carbon halogenated compounds in the Salmonella\/mammalian-microsome test. Environ Mutagen 2:59\u201366.","journal-title":"Environ Mutagen"},{"key":"1_CR60","doi-asserted-by":"publisher","first-page":"332","DOI":"10.1016\/0041-008X(86)90340-6","volume":"85","author":"WT Stott","year":"1986","unstructured":"Stott WT, Kastl PL (1986) Inhalation pharmacokinetics of technical grade 1,3-dichloro-propene in rats. Toxicol Appl Pharmacol 85:332\u2013341.","journal-title":"Toxicol Appl Pharmacol"},{"key":"1_CR61","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1016\/0272-0590(88)90145-5","volume":"11","author":"WT Stott","year":"1988","unstructured":"Stott WT, Young JT, Calhoun LL, Battjes JE (1988) Subchronic toxicity of inhaled technical-grade 1,3-dichloropropene in rats and mice. Fundam Appl Toxicol 11:207\u2013220.","journal-title":"Fundam Appl Toxicol"},{"key":"1_CR62","first-page":"250","volume":"45","author":"WT Stott","year":"1990","unstructured":"Stott WT, Waechter JM, Quast JT (1990) Letter to the editor. Arch Environ Health 45: 250\u2013253.","journal-title":"Arch Environ Health"},{"key":"1_CR63","first-page":"A415","volume":"12","author":"WT Stott","year":"1992","unstructured":"Stott WT, Mendrala AL, Redmond JM, Nwosu AF, Lomax LG (1992) Mechanism of 1,3-dichloropropene (1,3-D) induced toxicity in urinary bladder epithelium of mice. Toxicologist 12:A415.","journal-title":"Toxicologist"},{"key":"1_CR64","volume-title":"1,3-Dichloropropene: mechanism of tumorigenicity studies in Male B6C3F1 and Fischer 344 rats","author":"WT Stott","year":"1997","unstructured":"Stott WT, Gollapudi BB, Clements CM, Linscombe VA, Dittenber DA, Lick SJ, Johnson KA (1997) 1,3-Dichloropropene: mechanism of tumorigenicity studies in Male B6C3F1 and Fischer 344 rats. Dow Chemical Company, Midland, MI."},{"key":"1_CR65","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1093\/toxsci\/41.1.21","volume":"41","author":"WT Stott","year":"1998","unstructured":"Stott WT, Gilbert JR, McGuirk RJ, Brzak KA, Alexander LM, Dryzga MD, Mendrala AL, Bartels MJ (1998) Bioavailability and pharmacokinetics of microencapsulated 1,3-dichloropropene in rats. Toxicol Sci 41:21\u201328.","journal-title":"Toxicol Sci"},{"key":"1_CR66","volume-title":"The mutagenicity test on 1,3-dichloropropene in bacteria test system","author":"S Sudo","year":"1979","unstructured":"Sudo S, Kimura Y, Yamamoto K, Ichihara S (1979) The mutagenicity test on 1,3-dichloropropene in bacteria test system. Dow Chemical Company, Midland, MI."},{"key":"1_CR67","first-page":"1113","volume":"72","author":"R Talcott","year":"1984","unstructured":"Talcott R, King J (1984) Mutagenic impurities in 1,3-dichloropropene preparations. J Natl Cancer Inst 72:1113\u20131116.","journal-title":"J Natl Cancer Inst"},{"key":"1_CR68","first-page":"4007","volume-title":"Patty\u2019s Industrial Hygiene and Toxicology","author":"TR Torkelson","year":"1994","unstructured":"Torkelson TR (1994) Halogenated aliphatic hydrocarbons containing chlorine, bromine, and iodine. In: Clayton GD, Clayton FE (eds) Patty\u2019s Industrial Hygiene and Toxicology, 4th Ed., Vol. 2, Part E. Wiley, New York, pp 4007\u20134251.","edition":"4"},{"key":"1_CR69","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1080\/0002889778507603","volume":"38","author":"T Torkelson","year":"1977","unstructured":"Torkelson T, Oyen F (1977) The toxicity of 1,3-dichloropropene as determined by repeated exposure of laboratory animals. Am Ind Hyg Assoc J 38:217\u2013223.","journal-title":"Am Ind Hyg Assoc J"},{"key":"1_CR70","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1002\/em.2860070309","volume":"7","author":"R Valencia","year":"1985","unstructured":"Valencia R, Mason JM, Woodruff RC, Zimmering S (1985) Chemical mutagenesis testing in Drosophila. III. Results of 48 coded compounds tested for the national toxicology program. Environ Mutagen 7:325\u2013348.","journal-title":"Environ Mutagen"},{"key":"1_CR71","first-page":"1433","volume":"63","author":"BL Duuren Van","year":"1979","unstructured":"Van Duuren BL, Goldschmidt BM, Loewengart G, Smith AC, Melchionne S, Seidman I, Roth D (1979) Carcinogenicity of halogenated olefinic and aliphatic hydrocarbons in mice. J Natl Cancer Inst 63:1433\u20131439.","journal-title":"J Natl Cancer Inst"},{"key":"1_CR72","first-page":"646","volume":"48","author":"NJ Sittert van","year":"1991","unstructured":"van Sittert NJ, Veenstra GE, Dumas EP, Tordoir EF (1991) Letter to the editor. Br J Med 48:646\u2013648.","journal-title":"Br J Med"},{"key":"1_CR73","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1007\/BF01065321","volume":"20","author":"RTH Welie van","year":"1991","unstructured":"van Welie RTH, van Duyn P, Brouwer DH, van Hemmen JJ, Brouwer EJ, Vermeulen NPE (1991) Inhalation exposure to 1,3-dichloropropene in the Dutch flower-bulb culture. Part II. Biological monitoring by measurement of urinary excretion of two mer-capturic acid metabolites. Arch Environ Contam Toxicol 20:6\u201312.","journal-title":"Arch Environ Contam Toxicol"},{"key":"1_CR74","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1097\/00043764-198002000-00005","volume":"22","author":"JR Venable","year":"1980","unstructured":"Venable JR, McClimans CD, Flake RE, Dimick DB (1980) A fertility study of male employees engaged in the manufacture of glycerine. J Occup Med 22:87\u201391.","journal-title":"J Occup Med"},{"key":"1_CR75","volume-title":"Monitoring of occupational exposure to cis-1,3-dichloropropene and effects on liver and kidney, Part 2. Effects on liver and kidney","author":"AJW Verplanke","year":"1995","unstructured":"Verplanke AJW, Bloemen L, Brouwer EJ, Van Sittert NJ, Boogaard PJ, De Wolff FA (1995) Monitoring of occupational exposure to cis-1,3-dichloropropene and effects on liver and kidney, Part 2. Effects on liver and kidney. Universiteit van Amsterdam, Netherlands."},{"key":"1_CR76","doi-asserted-by":"publisher","first-page":"401","DOI":"10.1002\/em.2860090406","volume":"9","author":"W Hude von der","year":"1987","unstructured":"von der Hude W, Scheutwinkel M, Gramlich U, Fibler B, Basier A (1987) Genotoxicity of three-carbon compounds evaluated in the SCE test in vitro. Environ Mutagen 9: 401\u2013410.","journal-title":"Environ Mutagen"},{"key":"1_CR77","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/0165-1161(88)90023-4","volume":"203","author":"W Hude von der","year":"1988","unstructured":"von der Hude W, Behm C, Grtler R, Basier A (1988) Evaluation of the SOS chromotest. Mutat Res 203:81\u201394.","journal-title":"Mutat Res"},{"key":"1_CR78","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1007\/BF02034933","volume":"65","author":"RME Vos","year":"1991","unstructured":"Vos RME, van Welie RTH, Peters WHM, Evelo CTA, Boogaards JJP, Vermeulen NPE, van Bladeren PJ (1991) Genetic deficiency of human class mu glutathione S-transfer-ase isoenzymes in relation to the urinary excretion of the mercapturic acids of Z- and E-l,3-dichloropropene. Arch Toxicol 65:95\u201399.","journal-title":"Arch Toxicol"},{"key":"1_CR79","first-page":"A1090","volume":"13","author":"JM Waechter","year":"1992","unstructured":"Waechter JM, Brzak KA, McCarty LP, LaPack MA, Brownson PJ (1992) Cis-\/trans-1,3-dichloropropene: inhalation pharmacokinetics and metabolism in human volunteers. Toxicologist 13:A1090.","journal-title":"Toxicologist"},{"key":"1_CR80","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1016\/0009-2797(87)90016-0","volume":"61","author":"WP Watson","year":"1987","unstructured":"Watson WP, Brooks TM, Huckle KR, Hutson DH, Land KL, Smith RJ, Wright AS (1987) Microbial mutagenicity studies with (Z)-1,3-dichloropropene. Chem-Biol Interact 61:17\u201330.","journal-title":"Chem-Biol Interact"},{"key":"1_CR81","series-title":"Environmental Health Criteria","volume-title":"International Programme on Chemical Safety, 1,3-Dichloropropene, 1,2-Dichloropropane and Mixtures","author":"WHO (World Health Organization)","year":"1993","unstructured":"WHO (World Health Organization) (1993) International Programme on Chemical Safety, 1,3-Dichloropropene, 1,2-Dichloropropane and Mixtures. Environmental Health Criteria No. 146. World Health Organization, Geneva."},{"key":"1_CR82","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1080\/15287398609530879","volume":"18","author":"RSH Yang","year":"1986","unstructured":"Yang RSH, Huff JE, Boorman GA, Haseman JK, Kornreich M, Stookey JL (1986) Chronic toxicology and carcinogenesis studies of TELONE II by gavage in Fischer 344 rats and B6C3F1 mice. J Toxicol Environ Health 18:377\u2013392.","journal-title":"J Toxicol Environ Health"}],"container-title":["Reviews of Environmental Contamination and Toxicology"],"original-title":[],"link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/978-1-4613-0143-1_1.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,30]],"date-time":"2021-04-30T22:15:36Z","timestamp":1619820936000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/978-1-4613-0143-1_1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001]]},"ISBN":["9781468494815","9781461301431"],"references-count":82,"URL":"https:\/\/doi.org\/10.1007\/978-1-4613-0143-1_1","relation":{"is-part-of":[{"id-type":"doi","id":"https:\/\/doi.org\/10.1007\/978-1-4613-0143-1","asserted-by":"object"}]},"ISSN":["0179-5953"],"issn-type":[{"value":"0179-5953","type":"print"}],"subject":[],"published":{"date-parts":[[2001]]}}}