{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T20:46:33Z","timestamp":1776458793362,"version":"3.51.2"},"publisher-location":"New York, NY","reference-count":14,"publisher":"Springer New York","isbn-type":[{"value":"9781461447719","type":"print"},{"value":"9781461449898","type":"electronic"}],"license":[{"start":{"date-parts":[[2012,7,21]],"date-time":"2012-07-21T00:00:00Z","timestamp":1342828800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013]]},"DOI":"10.1007\/978-1-4614-4989-8_48","type":"book-chapter","created":{"date-parts":[[2012,8,9]],"date-time":"2012-08-09T14:46:00Z","timestamp":1344523560000},"page":"343-349","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Imaging the Redox States of Human Breast Cancer Core Biopsies"],"prefix":"10.1007","author":[{"given":"H. N.","family":"Xu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Tchou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Chance","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L. Z.","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2012,7,21]]},"reference":[{"key":"48_CR1","doi-asserted-by":"publisher","first-page":"4764","DOI":"10.1016\/S0021-9258(17)30079-0","volume":"254","author":"B Chance","year":"1979","unstructured":"Chance B, Schoener B, Oshino R et al (1979) Oxidation-reduction ratio studies of mitochondria in freeze-trapped samples. NADH and flavoprotein fluorescence signals. J Biol Chem 254:4764\u20134771","journal-title":"J Biol Chem"},{"key":"48_CR2","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1016\/0003-2697(85)90244-1","volume":"148","author":"B Quistorff","year":"1985","unstructured":"Quistorff B, Haselgrove JC, Chance B (1985) High spatial resolution readout of 3-D metabolic organ structure: an automated, low-temperature redox ratio-scanning instrument. Anal Biochem 148:389\u2013400","journal-title":"Anal Biochem"},{"key":"48_CR3","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1007\/978-0-387-71764-7_10","volume":"599","author":"LZ Li","year":"2007","unstructured":"Li LZ, Zhou R, Zhong T et al (2007) Predicting melanoma metastatic potential by optical and magnetic resonance imaging. Adv Exp Med Biol 599:67\u201378","journal-title":"Adv Exp Med Biol"},{"key":"48_CR4","doi-asserted-by":"publisher","first-page":"6608","DOI":"10.1073\/pnas.0901807106","volume":"106","author":"LZ Li","year":"2009","unstructured":"Li LZ, Zhou R, Xu HN et al (2009) Quantitative magnetic resonance and optical imaging biomarkers of melanoma metastatic potential. Proc Natl Acad Sci U S A 106:6608\u20136613","journal-title":"Proc Natl Acad Sci U S A"},{"key":"48_CR5","doi-asserted-by":"publisher","first-page":"036010","DOI":"10.1117\/1.3431714","volume":"15","author":"HN Xu","year":"2010","unstructured":"Xu HN, Nioka S, Glickson JD et al (2010) Quantitative mitochondrial redox imaging of breast cancer metastatic potential. J Biomed Opt 15:036010","journal-title":"J Biomed Opt"},{"key":"48_CR6","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1142\/S1793545809000735","volume":"2","author":"LZ Li","year":"2009","unstructured":"Li LZ, Xu HN, Ranji M et al (2009) Mitochondrial redox imaging for cancer diagnostic and therapeutic studies. J Innov Opt Health Sci 2:325\u2013341","journal-title":"J Innov Opt Health Sci"},{"key":"48_CR7","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1007\/978-1-4419-7756-4_28","volume":"201","author":"HN Xu","year":"2011","unstructured":"Xu HN, Nioka S, Chance B et al (2011) Heterogeneity of mitochondrial redox state in premalignant pancreas in a PTEN null transgenic mouse model. Adv Exp Med Biol 201:207\u2013213","journal-title":"Adv Exp Med Biol"},{"key":"48_CR8","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1142\/S1793545809000681","volume":"2","author":"HN Xu","year":"2009","unstructured":"Xu HN, Wu B, Nioka S et al (2009) Quantitative redox scanning of tissue samples using a calibration procedure. J Innov Opt Health Sci 2:375\u2013385","journal-title":"J Innov Opt Health Sci"},{"key":"48_CR9","doi-asserted-by":"crossref","unstructured":"Xu HN, Wu B, Nioka S et al (2009) Calibration of redox scanning for tissue samples. Proceedings of Biomedical Optics in San Jose, CA, Jan. 24, Ed. SPIE 7174:71742F","DOI":"10.1117\/12.809778"},{"key":"48_CR10","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1016\/0034-5687(81)90100-6","volume":"43","author":"NTS Evans","year":"1981","unstructured":"Evans NTS, Naylor PFD, Quinton TH (1981) The diffusion coefficient of oxygen in respiring kidney and tumour tissue. Respir Physiol 43:179","journal-title":"Respir Physiol"},{"key":"48_CR11","doi-asserted-by":"publisher","first-page":"691","DOI":"10.1016\/0360-3016(88)90313-6","volume":"15","author":"K Groebe","year":"1988","unstructured":"Groebe K, Vaupel P (1988) Evaluation of oxygen diffusion distances in human breast cancer xenografts using tumor-specific in vivo data: role of various mechanisms in the development of tumor hypoxia. Int J Radiat Oncol Biol Phys 15:691","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"48_CR12","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1113\/jphysiol.1919.sp001838","volume":"52","author":"A Krogh","year":"1919","unstructured":"Krogh A (1919) The rate of diffusion of gases through animal tissues, with some remarks on the coefficient of invasion. J Physiol 52:391\u2013408","journal-title":"J Physiol"},{"key":"48_CR13","doi-asserted-by":"publisher","first-page":"1173","DOI":"10.1038\/2151173a0","volume":"215","author":"JDB Macdougall","year":"1967","unstructured":"Macdougall JDB, McCabe M (1967) Diffusion coefficient of oxygen through tissues. Nature 215:1173","journal-title":"Nature"},{"key":"48_CR14","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1007\/0-387-26206-7_44","volume":"566","author":"P Vaupel","year":"2005","unstructured":"Vaupel P, Mayer A, Briest S et al (2005) Hypoxia in breast cancer: role of blood flow, oxygen diffusion distances, and anemia in the development of oxygen depletion. Adv Exp Med Biol 566:333\u2013342","journal-title":"Adv Exp Med Biol"}],"container-title":["Advances in Experimental Medicine and Biology","Oxygen Transport to Tissue XXXIV"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/978-1-4614-4989-8_48","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,13]],"date-time":"2025-02-13T17:17:13Z","timestamp":1739467033000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/978-1-4614-4989-8_48"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,7,21]]},"ISBN":["9781461447719","9781461449898"],"references-count":14,"URL":"https:\/\/doi.org\/10.1007\/978-1-4614-4989-8_48","relation":{},"ISSN":["0065-2598","2214-8019"],"issn-type":[{"value":"0065-2598","type":"print"},{"value":"2214-8019","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,7,21]]},"assertion":[{"value":"21 July 2012","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}}]}}