{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,11]],"date-time":"2026-11-11T23:20:58Z","timestamp":1794439258785,"version":"4.9.1"},"publisher-location":"New York, NY","reference-count":33,"publisher":"Springer New York","isbn-type":[{"value":"9781461460923","type":"print"},{"value":"9781461460930","type":"electronic"}],"license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013]]},"DOI":"10.1007\/978-1-4614-6093-0_21","type":"book-chapter","created":{"date-parts":[[2013,2,7]],"date-time":"2013-02-07T15:36:30Z","timestamp":1360251390000},"page":"217-229","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Effects of Taurine on Myocardial cGMP\/cAMP Ratio, Antioxidant Ability, and Ultrastructure in Cardiac Hypertrophy Rats Induced by Isoproterenol"],"prefix":"10.1007","author":[{"given":"Qunhui","family":"Yang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiancheng","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaofeng","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiufeng","family":"Lv","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shumei","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianmin","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2013,1,10]]},"reference":[{"key":"21_CR00211","doi-asserted-by":"publisher","first-page":"750","DOI":"10.1161\/01.CIR.88.2.750","volume":"88","author":"JE Adams 3rd","year":"1993","unstructured":"Adams JE 3rd, Abendschein DR, Jaffe AS (1993) Biochemical markers of myocardial injury. Is MB creatine kinase the choice for the 1990s? Circulation 88:750\u2013763","journal-title":"Circulation"},{"key":"21_CR00212","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1007\/s10741-006-9195-3","volume":"1","author":"ML Allard","year":"2006","unstructured":"Allard ML, Jeejeebhoy KN, Sole MJ (2006) The management of conditioned nutritional requirements in heart failure. Heart Fail Rev 1:75\u201382","journal-title":"Heart Fail Rev"},{"key":"21_CR00213","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1016\/S0014-2999(00)00483-0","volume":"403","author":"M Azuma","year":"2000","unstructured":"Azuma M, Takahashi K, Fukuda T, Ohyabu Y, Yamamoto I, Kim S, Iwao H, Schaffer SW, Azuma J (2000) Taurine attenuates hypertrophy induced by angiotensin II in cultured neonatal rat cardiac myocytes. Eur J Pharmacol 403:181\u2013188","journal-title":"Eur J Pharmacol"},{"key":"21_CR00214","doi-asserted-by":"publisher","first-page":"607","DOI":"10.1016\/S0008-6363(99)00163-7","volume":"43","author":"JL Balligand","year":"1999","unstructured":"Balligand JL (1999) Regulation of cardiac beta-adrenergic response by nitric oxide. Cardiovasc Res 43:607\u2013620","journal-title":"Cardiovasc Res"},{"key":"21_CR00215","doi-asserted-by":"publisher","first-page":"812","DOI":"10.1172\/JCI119883","volume":"101","author":"A Calderone","year":"1998","unstructured":"Calderone A, Thaik CM, Takahashi N, Chang DF, Colucci WS (1998) Nitricoxide, atrial natriuretic peptide, and cyclic GMP inhibit the growth-promoting effects of norepinephrine in cardiac myocytes and fibroblasts. J Clin Invest 101:812\u2013818","journal-title":"J Clin Invest"},{"key":"21_CR00216","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1007\/s00726-004-0096-2","volume":"27","author":"L Chang","year":"2004","unstructured":"Chang L, Xu J, Yu F, Zhao J, Tang X, Tang C (2004) Taurine protected myocardial mitochondria injury induced by hyperhomocysteinemia in rats. Amino Acids 27:37\u201348","journal-title":"Amino Acids"},{"key":"21_CR00217","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1023\/A:1022808224917","volume":"245","author":"A Chattopadhyay","year":"2003","unstructured":"Chattopadhyay A, Biswas S, Bandyopadhyay D, Sarkar C, Datta AG (2003) Effect of isoproterenol on lipid peroxidation and antioxidant enzymes of myocardial tissue of mice and protection by quinidine. Mol Cell Biochem 245:43\u201349","journal-title":"Mol Cell Biochem"},{"key":"21_CR00218","doi-asserted-by":"crossref","first-page":"1892","DOI":"10.1097\/00029330-200611020-00008","volume":"119","author":"XL Gan","year":"2006","unstructured":"Gan XL, Hei ZQ, Huang HQ, Chen LX, Li SR, Cai J (2006) Effect of Astragalus membranaceus injection on the activity of the intestinal mucosal mast cells after hemorrhagic shock-reperfusion in rats. Chin Med J 119:1892\u20131898","journal-title":"Chin Med J"},{"key":"21_CR00219","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s004240051121","volume":"439","author":"S Grazyna","year":"1999","unstructured":"Grazyna S, Hinrik S, Michael S, Yvonne BJ, James PM (1999) Altered phosphorylation of sarcoplasmic reticulum contributes to the diminished contractile response to isoproterenol in hypertrophied rat hearts. Eur J Physiol 439:1\u201310","journal-title":"Eur J Physiol"},{"key":"21_CR002110","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1097\/00005344-199108000-00008","volume":"18","author":"T Hamaguchi","year":"1991","unstructured":"Hamaguchi T, Azuma J, Schaffer S (1991) Interaction of taurine with methionine: inhibition of myocardial phospholipid methyltransferase. J Cardiovasc Pharmacol 18:224\u2013230","journal-title":"J Cardiovasc Pharmacol"},{"key":"21_CR002111","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1161\/01.CIR.97.2.161","volume":"97","author":"JM Hare","year":"1998","unstructured":"Hare JM, Givertz MM, Creager MA, Colucci WS (1998) Increased sensitivity to nitric oxide synthase inhibition in patients with heart failure: potentiation of beta-adrenergic inotropic responsiveness. Circulation 97:161\u2013166","journal-title":"Circulation"},{"key":"21_CR002112","doi-asserted-by":"publisher","first-page":"1370","DOI":"10.1056\/NEJMra072139","volume":"358","author":"JA Hill","year":"2008","unstructured":"Hill JA, Olson EN (2008) Cardiac plasticity. N Engl J Med 358:1370\u20131380","journal-title":"N Engl J Med"},{"key":"21_CR002113","doi-asserted-by":"publisher","first-page":"1187","DOI":"10.1126\/science.184.4142.1187","volume":"184","author":"R Huxtable","year":"1974","unstructured":"Huxtable R, Bressler R (1974) Taurine concentrations in congestive heart failure. Science 184:1187\u20131188","journal-title":"Science"},{"key":"21_CR002114","doi-asserted-by":"publisher","first-page":"927","DOI":"10.1016\/j.yjmcc.2008.03.001","volume":"44","author":"T Ito","year":"2008","unstructured":"Ito T, Kimura Y, Uozumi Y, Takai M, Muraoka S, Matsuda T, Ueki K, Yoshiyama M, Ikawa M, Okabe M, Schaffer SW, Fujio Y, Azuma J (2008) Taurine depletion caused by knocking out the taurine transporter gene leads to cardiomyopathy with cardiac atrophy. J Mol Cell Cardiol 44:927\u2013937","journal-title":"J Mol Cell Cardiol"},{"key":"21_CR002115","doi-asserted-by":"publisher","first-page":"170","DOI":"10.1007\/s11748-007-0214-7","volume":"56","author":"K Itoh","year":"2008","unstructured":"Itoh K, Minakawa M, Ono Y, Tsushima K, Fukui K, Fukuda I (2008) Role of oxidative stress in hypertrophied myoblasts stimulated by isoproterenol. Gen Thorac Cardiovasc Surg 56:170\u2013176","journal-title":"Gen Thorac Cardiovasc Surg"},{"key":"21_CR002116","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1016\/j.freeradbiomed.2008.09.025","volume":"46","author":"Y Li","year":"2009","unstructured":"Li Y, Arnold JMO, Pampillo M, Babwah AV, Peng TQ (2009) Taurine prevents cardiomyocyte death by inhibiting NADPH oxidase-mediated calpain activation. Free Radic Biol Med 46:51\u201361","journal-title":"Free Radic Biol Med"},{"key":"21_CR002117","doi-asserted-by":"publisher","first-page":"1957","DOI":"10.1006\/jmcc.1996.0188","volume":"28","author":"JB Lombardini","year":"1996","unstructured":"Lombardini JB (1996) Taurine depletion in the intact animal stimulates in vitro phosphorylation of a 44-kDa protein present in the mitochondrial fraction of the rat heart. J Mol Cell Cardiol 28:1957\u20131961","journal-title":"J Mol Cell Cardiol"},{"key":"21_CR002118","doi-asserted-by":"publisher","first-page":"470","DOI":"10.1161\/01.CIR.102.4.470","volume":"102","author":"BH Lorell","year":"2000","unstructured":"Lorell BH, Carabello BA (2000) Left ventricular hypertrophy: pathogenesis, detection, and prognosis. Circulation 102:470\u2013479","journal-title":"Circulation"},{"key":"21_CR002119","doi-asserted-by":"publisher","first-page":"541","DOI":"10.1016\/0002-8703(91)90724-V","volume":"121","author":"NS Moise","year":"1991","unstructured":"Moise NS, Pacioretty LM, Kallfelz FA, Stipanuk MH, King JM, Gilmour RF Jr (1991) Dietary taurine deficiency and dilated cardiomyopathy in the fox. Am Heart J 121:541\u2013547","journal-title":"Am Heart J"},{"key":"21_CR002120","doi-asserted-by":"publisher","first-page":"1877","DOI":"10.1161\/01.CIR.0000124229.40424.80","volume":"109","author":"GY Oudit","year":"2004","unstructured":"Oudit GY, Trivieri MG, Khaper N, Husain T, Wilson GJ, Liu P, Sole MJ, Backx PH (2004) Taurine supplementation reduces oxidative stress and improves cardiovascular function in an iron-overload murine model. Circulation 109:1877\u20131885","journal-title":"Circulation"},{"key":"21_CR002121","doi-asserted-by":"publisher","first-page":"764","DOI":"10.1126\/science.3616607","volume":"237","author":"PD Pion","year":"1987","unstructured":"Pion PD, Kittleson MD, Rogers QR, Morris JG (1987) Myocardial failure in cat associated with low plasma taurine:a reversible cardiomyopathy. Science 237:764\u2013768","journal-title":"Science"},{"key":"21_CR002122","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1186\/1749-8090-6-31","volume":"6","author":"MA Sahin","year":"2011","unstructured":"Sahin MA, Yucel O, Guler A, Doganci S, Jahollari A, Cingoz F, Arslan S, Gamsizkan M, Yaman H, Demirkilic U (2011) Is there any cardioprotective role of Taurine during cold ischemic period following global myocardial ischemia? J Cardiothorac Surg 6:31\u201338","journal-title":"J Cardiothorac Surg"},{"key":"21_CR002123","doi-asserted-by":"publisher","first-page":"379","DOI":"10.1006\/jmcc.2002.1526","volume":"34","author":"DB Sawyer","year":"2002","unstructured":"Sawyer DB, Siwik DA, Xiao L, Pimentel DR, Singh K, Colucci WS (2002) Role of oxidative stress in myocardial hypertrophy and failure. J Mol Cell Cardiol 34:379\u2013388","journal-title":"J Mol Cell Cardiol"},{"key":"21_CR002124","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1139\/Y08-110","volume":"87","author":"SW Schaffer","year":"2009","unstructured":"Schaffer SW, Azuma J, Mozaffari M (2009) Role of antioxidant activity of taurine in diabetes. Can J Physiol Pharmacol 87:91\u201399","journal-title":"Can J Physiol Pharmacol"},{"issue":"10","key":"21_CR002125","first-page":"910","volume":"23","author":"YR Shi","year":"2002","unstructured":"Shi YR, Bu DF, Qi YF, Gao L, Jiang HF, Pang YZ, Tang CS, Du JB (2002) Dysfunction of myocardial taurine transport and effect of taurine supplement in rats with isoproterenol-induced myocardial injury. Acta Pharmacol Sin 23(10):910\u2013918","journal-title":"Acta Pharmacol Sin"},{"key":"21_CR002126","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1211\/jpp.57.10.0010","volume":"57","author":"KS Shiny","year":"2005","unstructured":"Shiny KS, Kumar SHS, Farvin KHS, Anandan R, Devadasan K (2005) Protective effect of taurine on myocardial antioxidant status in isoprenaline-induced myocardial infarction in rats. J Pharm Pharmacol 57:1\u20135","journal-title":"J Pharm Pharmacol"},{"key":"21_CR002127","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1097\/00005344-199908000-00008","volume":"34","author":"M Straznicka","year":"1999","unstructured":"Straznicka M, Gong G, Yan L, Scholz PM, Weiss HR (1999) Cyclic GMP protein kinase mediates negative metabolic and functional effects of cyclic GMP in control and hypertrophied rabbit cardiac myocytes. J Cardiovasc Pharmacol 34:229\u2013236","journal-title":"J Cardiovasc Pharmacol"},{"issue":"6","key":"21_CR002128","doi-asserted-by":"publisher","first-page":"1467","DOI":"10.1172\/JCI28884","volume":"116","author":"JC Tardiff","year":"2006","unstructured":"Tardiff JC (2006) Cardiac hypertrophy: stressing out the heart. J Clin Invest 116(6):1467\u20131470","journal-title":"J Clin Invest"},{"key":"21_CR002129","doi-asserted-by":"publisher","first-page":"1020","DOI":"10.1161\/01.RES.84.9.1020","volume":"84","author":"MG Vila-Petroff","year":"1999","unstructured":"Vila-Petroff MG, Younes A, Egan J, Lakatta EG, Sollott SJ (1999) Activation of distinct cAMP-dependent and cGMP-dependent pathways by nitric oxide in cardiac myocytes. Circ Res 84:1020\u20131031","journal-title":"Circ Res"},{"key":"21_CR002130","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1042\/bj2810021","volume":"281","author":"T Wallimann","year":"1992","unstructured":"Wallimann T, Wyss M, Brdiczka D, Nicolay K, Eppenberger HM (1992) Intracellular compartmentation, structure and function of creatine kinase isoenzymes in tissues with high and fluctuating energy demands: the \u201cphosphocreatine circuit\u201d for cellular energy homeostasis. Biochem J 281:21\u201340","journal-title":"Biochem J"},{"issue":"2","key":"21_CR002131","first-page":"57","volume":"13","author":"YJ Xu","year":"2008","unstructured":"Xu YJ, Arneja AS, Tappia PS, Dhalla NS (2008) The potential health benefits of taurine in cardiovascular disease. Exp Clin Cardiol 13(2):57\u201365","journal-title":"Exp Clin Cardiol"},{"issue":"4","key":"21_CR002132","doi-asserted-by":"publisher","first-page":"453","DOI":"10.1291\/hypres.24.453","volume":"24","author":"Y Yamori","year":"2001","unstructured":"Yamori Y, Liu L, Ikeda K, Miura A, Mizushima S, Miki T, Nara Y (2001) Distribution of twenty-four hour urinary taurine excretion and association with ischemic heart disease mortality in 24 populations of 16 countries: results from the WHOCARDIAC study. Hypertens Res 24(4):453","journal-title":"Hypertens Res"},{"issue":"Suppl 1","key":"21_CR002133","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1186\/1423-0127-17-S1-S9","volume":"17","author":"JC Yang","year":"2010","unstructured":"Yang JC, Wu GF, Feng Y, Lu QF, Lin SM, Hu JM (2010) Effects of taurine on male reproduction in rats of different ages. J Biomed Sci 17(Suppl 1):59\u201366","journal-title":"J Biomed Sci"}],"container-title":["Advances in Experimental Medicine and Biology","Taurine 8"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/978-1-4614-6093-0_21","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,30]],"date-time":"2023-01-30T15:18:20Z","timestamp":1675091900000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/978-1-4614-6093-0_21"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013]]},"ISBN":["9781461460923","9781461460930"],"references-count":33,"URL":"https:\/\/doi.org\/10.1007\/978-1-4614-6093-0_21","relation":{"is-part-of":[{"id-type":"doi","id":"https:\/\/doi.org\/10.1007\/978-1-4614-6093-0","asserted-by":"object"}]},"ISSN":["0065-2598"],"issn-type":[{"value":"0065-2598","type":"print"}],"subject":[],"published":{"date-parts":[[2013]]},"assertion":[{"value":"10 January 2013","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}}]}}