{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T14:49:42Z","timestamp":1777301382993,"version":"3.51.4"},"publisher-location":"New York, NY","reference-count":182,"publisher":"Springer New York","isbn-type":[{"value":"9781461477822","type":"print"},{"value":"9781461477839","type":"electronic"}],"license":[{"start":{"date-parts":[[2013,7,11]],"date-time":"2013-07-11T00:00:00Z","timestamp":1373500800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2013,7,11]],"date-time":"2013-07-11T00:00:00Z","timestamp":1373500800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014]]},"DOI":"10.1007\/978-1-4614-7783-9_10","type":"book-chapter","created":{"date-parts":[[2013,8,16]],"date-time":"2013-08-16T07:11:20Z","timestamp":1376637080000},"page":"151-172","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Sperm Selection: Effect on Sperm DNA Quality"],"prefix":"10.1007","author":[{"given":"Lodovico","family":"Parmegiani","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gra\u00e7iela Estela","family":"Cognigni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco","family":"Filicori","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2013,7,11]]},"reference":[{"key":"10_CR00101","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1080\/01485010701730963","volume":"53","author":"L Ahmad","year":"2007","unstructured":"Ahmad L, Jalali S, Shami SA et al (2007) Sperm preparation: DNA damage by comet assay in normo- and teratozoospermics. Arch Androl 53:325\u2013338","journal-title":"Arch Androl"},{"key":"10_CR00102","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1002\/(SICI)1097-010X(19991101)284:6<696::AID-JEZ11>3.0.CO;2-E","volume":"284","author":"A Ahmadi","year":"1999","unstructured":"Ahmadi A, Ng SC (1999a) Fertilizing ability of DNA-damaged spermatozoa. J Exp Zool 284:696\u2013704","journal-title":"J Exp Zool"},{"key":"10_CR00103","doi-asserted-by":"crossref","first-page":"2279","DOI":"10.1093\/humrep\/14.9.2279","volume":"14","author":"A Ahmadi","year":"1999","unstructured":"Ahmadi A, Ng SC (1999b) Developmental capacity of damaged spermatozoa. Hum Reprod 14:2279\u20132284","journal-title":"Hum Reprod"},{"key":"10_CR00104","doi-asserted-by":"crossref","first-page":"2365","DOI":"10.1093\/humrep\/dei014","volume":"20","author":"JG Alvarez","year":"2005","unstructured":"Alvarez JG (2005) The predictive value of sperm chromatin structure assay. Hum Reprod 20:2365\u20132367","journal-title":"Hum Reprod"},{"key":"10_CR00105","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1016\/S1472-6483(10)60150-2","volume":"16","author":"M Antinori","year":"2008","unstructured":"Antinori M, Licata E, Dani G et al (2008) Intracytoplasmic morphologically selected sperm injection: a prospective randomized trial. Reprod Biomed Online 16:835\u2013841","journal-title":"Reprod Biomed Online"},{"key":"10_CR00106","doi-asserted-by":"crossref","first-page":"356","DOI":"10.2164\/jandrol.110.012005","volume":"32","author":"C Avenda\u00f1o","year":"2011","unstructured":"Avenda\u00f1o C, Oehninger S (2011) DNA fragmentation in morphologically normal spermatozoa: how much should we be concerned in the ICSI era? J Androl 32:356\u2013363","journal-title":"J Androl"},{"key":"10_CR00107","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1016\/j.fertnstert.2009.02.050","volume":"94","author":"C Avenda\u00f1o","year":"2010","unstructured":"Avenda\u00f1o C, Franchi A, Duran H et al (2010) DNA fragmentation of normal spermatozoa negatively impacts embryo quality and intracytoplasmic sperm injection outcome. Fertil Steril 94:549\u2013557","journal-title":"Fertil Steril"},{"key":"10_CR00108","doi-asserted-by":"crossref","first-page":"1887","DOI":"10.1093\/humrep\/deg385","volume":"18","author":"B Balaban","year":"2003","unstructured":"Balaban B, Lundin K, Morrell JM et al (2003) An alternative to PVP for slowing sperm prior to ICSI. Hum Reprod 18:1887\u20131889","journal-title":"Hum Reprod"},{"key":"10_CR00109","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1016\/j.rbmo.2010.11.003","volume":"22","author":"B Balaban","year":"2011","unstructured":"Balaban B, Yakin K, Alatas C et al (2011) Clinical outcome of intracytoplasmic injection of spermatozoa morphologically selected under high magnification: a prospective randomized study. Reprod Biomed Online 22:472\u2013476","journal-title":"Reprod Biomed Online"},{"key":"10_CR001010","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1080\/1464727012000199371","volume":"4","author":"Y Barak","year":"2001","unstructured":"Barak Y, Menezo Y, Veiga A et al (2001) A physiological replacement for polyvinylpyrrolidone (PVP) in assisted reproductive technology. Hum Fertil 4:99\u2013103","journal-title":"Hum Fertil"},{"key":"10_CR001011","doi-asserted-by":"crossref","first-page":"2069","DOI":"10.1093\/oxfordjournals.humrep.a138395","volume":"9","author":"B Bartoov","year":"1994","unstructured":"Bartoov B, Eltes F, Pansky M et al (1994) Improved diagnosis of male fertility potential via a combination of quantitative ultramorphology and routine semen analyses. Hum Reprod 9:2069\u20132075","journal-title":"Hum Reprod"},{"key":"10_CR001012","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1056\/NEJM200110043451416","volume":"345","author":"B Bartoov","year":"2001","unstructured":"Bartoov B, Berkovitz A, Eltes F (2001) Selection of spermatozoa with normal nuclei to improve the pregnancy rate with intracytoplasmic sperm injection. N Engl J Med 345:1067\u20131068","journal-title":"N Engl J Med"},{"key":"10_CR001013","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/j.1939-4640.2002.tb02595.x","volume":"23","author":"B Bartoov","year":"2002","unstructured":"Bartoov B, Berkovitz A, Eltes F et al (2002) Real-time fine morphology of motile human sperm cells is associated with IVF-ICSI outcome. J Androl 23:1\u20138","journal-title":"J Androl"},{"key":"10_CR001014","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.1016\/j.fertnstert.2003.05.016","volume":"80","author":"B Bartoov","year":"2003","unstructured":"Bartoov B, Berkovitz A, Eltes F et al (2003) Pregnancy rates are higher with intracytoplasmic morphologically selected sperm injection than with conventional intracytoplasmic injection. Fertil Steril 80:1413\u20131419","journal-title":"Fertil Steril"},{"key":"10_CR001015","doi-asserted-by":"crossref","first-page":"1713","DOI":"10.1093\/humrep\/deq098","volume":"25","author":"J Bellver","year":"2010","unstructured":"Bellver J, Meseguer M, Muriel L et al (2010) Chromosome microdeletions, sperm DNA fragmentation and sperm oxidative stress as causes of recurrent spontaneous abortion of unknown etiology. Hum Reprod 25:1713\u20131721","journal-title":"Hum Reprod"},{"key":"10_CR001016","doi-asserted-by":"crossref","first-page":"1752","DOI":"10.1093\/humrep\/der121","volume":"7","author":"F Belva","year":"2011","unstructured":"Belva F, De Schrijver F, Tournaye H et al (2011) Neonatal outcome of 724 children born after ICSI using non-ejaculated sperm. Hum Reprod 7:1752\u20131758","journal-title":"Hum Reprod"},{"key":"10_CR001017","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1093\/humrep\/deg228","volume":"18","author":"M Benchaib","year":"2003","unstructured":"Benchaib M, Braun V, Lornage J et al (2003) Sperm DNA fragmentation decreases the pregnancy rate in an assisted reproductive technique. Hum Reprod 18:1023\u20131028","journal-title":"Hum Reprod"},{"key":"10_CR001018","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1093\/humrep\/deh545","volume":"20","author":"A Berkovitz","year":"2005","unstructured":"Berkovitz A, Eltes F, Yaari S et al (2005) The morphological normalcy of the sperm nucleus and pregnancy rate of intracytoplasmic injection with morphologically selected sperm. Hum Reprod 20:185\u2013190","journal-title":"Hum Reprod"},{"key":"10_CR001019","doi-asserted-by":"crossref","first-page":"1787","DOI":"10.1093\/humrep\/del049","volume":"21","author":"A Berkovitz","year":"2006","unstructured":"Berkovitz A, Eltes F, Ellenbogen A et al (2006a) Does the presence of nuclear vacuoles in human sperm selected for ICSI affect pregnancy outcome? Hum Reprod 21:1787\u20131790","journal-title":"Hum Reprod"},{"key":"10_CR001020","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1016\/S1472-6483(10)61191-1","volume":"12","author":"A Berkovitz","year":"2006","unstructured":"Berkovitz A, Eltes F, Lederman H et al (2006b) How to improve IVF-ICSI outcome by sperm selection. Reprod Biomed Online 12:634\u2013638","journal-title":"Reprod Biomed Online"},{"key":"10_CR001021","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1093\/humupd\/2.2.103","volume":"2","author":"H Billig","year":"1996","unstructured":"Billig H, Chun SY, Eisenhauer K et al (1996) Gonadal cell apoptosis: hormone-regulated cell demise. Hum Reprod Update 2:103\u2013117","journal-title":"Hum Reprod Update"},{"key":"10_CR001022","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1016\/j.fertnstert.2009.08.063","volume":"93","author":"M Black","year":"2010","unstructured":"Black M, de Liu Y, Bourne H H et al (2010) Comparison of outcomes of conventional intracytoplasmic sperm injection and intracytoplasmic sperm injection using sperm bound to the zona pellucida of immature oocytes. Fertil Steril 93:672\u2013674","journal-title":"Fertil Steril"},{"key":"10_CR001023","doi-asserted-by":"crossref","first-page":"360","DOI":"10.2164\/jandrol.04056","volume":"26","author":"GB Boe-Hansen","year":"2005","unstructured":"Boe-Hansen GB, Ersboll AK, Christensen P (2005) Variability and laboratory factors affecting the sperm chromatin structure assay in human semen. J Androl 26:360\u2013368","journal-title":"J Androl"},{"key":"10_CR001024","doi-asserted-by":"crossref","first-page":"1650","DOI":"10.1093\/humrep\/der129","volume":"7","author":"F Boitrelle","year":"2011","unstructured":"Boitrelle F, Ferfouri F, Petit JM et al (2011) Large human sperm vacuoles observed in motile spermatozoa under high magnification: nuclear thumbprints linked to failure of chromatin condensation. Hum Reprod 7:1650\u20131658","journal-title":"Hum Reprod"},{"key":"10_CR001025","doi-asserted-by":"crossref","first-page":"2600","DOI":"10.1093\/humrep\/17.10.2600","volume":"17","author":"M Bonduelle","year":"2002","unstructured":"Bonduelle M, Van Assche E, Joris H et al (2002) Prenatal testing in ICSI pregnancies: incidence of chromosomal anomalies in 1586 karyotypes and relation to sperm parameters. Hum Reprod 17:2600\u20132614","journal-title":"Hum Reprod"},{"key":"10_CR001026","doi-asserted-by":"crossref","first-page":"2876","DOI":"10.1093\/humrep\/del251","volume":"21","author":"A Borini","year":"2006","unstructured":"Borini A, Tarozzi N, Bizzaro D et al (2006) Sperm DNA fragmentation: paternal effect on early post-implantation embryo development in ART. Hum Reprod 21:2876\u20132881","journal-title":"Hum Reprod"},{"key":"10_CR001027","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.1093\/humrep\/deh280","volume":"19","author":"M Bungum","year":"2004","unstructured":"Bungum M, Humaidan P, Span\u00f2 M et al (2004) The predictive value of sperm chromatin structure assay (SCSA) parameters for the outcome of intrauterine insemination, IVF and ICSI. Hum Reprod 19:1401\u20131408","journal-title":"Hum Reprod"},{"key":"10_CR001028","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1093\/humrep\/del326","volume":"22","author":"M Bungum","year":"2007","unstructured":"Bungum M, Humaidan P, Axmon A et al (2007) Sperm DNA integrity assessment in prediction of assisted reproduction technology outcome. Hum Reprod 22:174\u2013179","journal-title":"Hum Reprod"},{"key":"10_CR001029","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1093\/humrep\/dem353","volume":"23","author":"M Bungum","year":"2008","unstructured":"Bungum M, Span\u00f2 M, Humaidan P et al (2008) Sperm chromatin structure assay parameters measured after density gradient centrifugation are not predictive for the outcome of ART. Hum Reprod 23:4\u201310","journal-title":"Hum Reprod"},{"key":"10_CR001030","doi-asserted-by":"crossref","first-page":"2298","DOI":"10.1093\/humrep\/deh438","volume":"19","author":"N Burrello","year":"2004","unstructured":"Burrello N, Arcidiacono G, Vicari E et al (2004) Morphologically normal spermatozoa of patients with secretory oligo-astheno-teratozoospermia have an increased aneuploidy rate. Hum Reprod 19:2298\u20132302","journal-title":"Hum Reprod"},{"key":"10_CR001031","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1080\/01485010290099390","volume":"49","author":"DT Carrell","year":"2003","unstructured":"Carrell DT, Liu L, Peterson CM et al (2003) Sperm DNA fragmentation is increased in couples with unexplained recurrent pregnancy loss. Arch Androl 49:49\u201355","journal-title":"Arch Androl"},{"key":"10_CR001032","doi-asserted-by":"crossref","first-page":"1616","DOI":"10.1016\/j.fertnstert.2008.08.088","volume":"92","author":"NG Cassuto","year":"2009","unstructured":"Cassuto NG, Bouret D, Plouchart JM et al (2009) A new real-time morphology classification for human spermatozoa: a link for fertilization and improved embryo quality. Fertil Steril 92:1616\u20131625","journal-title":"Fertil Steril"},{"key":"10_CR001033","doi-asserted-by":"crossref","first-page":"324","DOI":"10.2164\/jandrol.110.011015","volume":"32","author":"J Castillo","year":"2011","unstructured":"Castillo J, Simon L, de Mateo S et al (2011) Protamine\/DNA ratios and DNA damage in native and density gradient centrifugated sperm from infertile patients. J Androl 32:324\u2013332","journal-title":"J Androl"},{"key":"10_CR001034","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1016\/S1472-6483(10)61891-3","volume":"7","author":"S Cayli","year":"2003","unstructured":"Cayli S, Jakab A, Ovari L et al (2003) Biochemical markers of sperm function: male fertility and sperm selection for ICSI. Reprod Biomed Online 7:462\u2013468","journal-title":"Reprod Biomed Online"},{"key":"10_CR001035","doi-asserted-by":"crossref","first-page":"2052","DOI":"10.1093\/humrep\/deh361","volume":"19","author":"C Celik-Ozenci","year":"2004","unstructured":"Celik-Ozenci C, Jakab A, Kovacs T et al (2004) Sperm selection for ICSI: shape properties do not predict the absence or presence of numerical chromosomal aberrations. Hum Reprod 19:2052\u20132059","journal-title":"Hum Reprod"},{"key":"10_CR001036","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1016\/j.fertnstert.2005.07.1302","volume":"85","author":"PJ Chan","year":"2006","unstructured":"Chan PJ, Jacobson JD, Corselli JU et al (2006) A simple zeta method for sperm selection based on membrane charge. Fertil Steril 85:481\u2013486","journal-title":"Fertil Steril"},{"key":"10_CR001037","doi-asserted-by":"crossref","first-page":"53","DOI":"10.2164\/jandrol.05068","volume":"27","author":"KR Chohan","year":"2006","unstructured":"Chohan KR, Griffin JT, Lafromboise M et al (2006) Comparison of chromatin assays for DNA fragmentation evaluation in human sperm. J Androl 27:53\u201359","journal-title":"J Androl"},{"key":"10_CR001038","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1016\/j.fertnstert.2007.04.055","volume":"89","author":"JA Collins","year":"2008","unstructured":"Collins JA, Barnhart KT, Schlegel PN (2008) Do sperm DNA integrity tests predict pregnancy with in vitro fertilization. Fertil Steril 89:823\u2013831","journal-title":"Fertil Steril"},{"key":"10_CR001039","doi-asserted-by":"crossref","first-page":"1443","DOI":"10.1016\/j.fertnstert.2004.04.053","volume":"82","author":"LH Dalzell","year":"2004","unstructured":"Dalzell LH, McVicar CM, McClure N et al (2004) Effects of short and long incubations on DNA fragmentation of testicular sperm. Fertil Steril 82:1443\u20131445","journal-title":"Fertil Steril"},{"key":"10_CR001040","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1016\/j.fertnstert.2010.11.018","volume":"95","author":"RC de Figueira","year":"2011","unstructured":"de Figueira RC, Braga DP, Setti AS et al (2011) Morphological nuclear integrity of sperm cells is associated with preimplantation genetic aneuploidy screening cycle outcomes. Fertil Steril 95:990\u2013993","journal-title":"Fertil Steril"},{"key":"10_CR001041","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1016\/j.rbmo.2009.09.020","volume":"19","author":"BD de Paes Almeida Ferreira","year":"2009","unstructured":"de Paes Almeida Ferreira BD, Iaconelli A Jr, de Cassia Savio FR et al (2009) Outcome of ICSI using zona pellucida-bound spermatozoa and conventionally selected spermatozoa. Reprod Biomed Online 19:802\u2013807","journal-title":"Reprod Biomed Online"},{"issue":"1","key":"10_CR001042","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/S0015-0282(02)04571-5","volume":"79","author":"A De Vos","year":"2003","unstructured":"De Vos A, Van De Velde H, Joris H et al (2003) Influence of individual sperm morphology on fertilization, embryo morphology, and pregnancy outcome of intracytoplasmic sperm injection. Fertil Steril 79(1):42\u201348","journal-title":"Fertil Steril"},{"key":"10_CR001043","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1093\/humrep\/des435","volume":"28","author":"A De Vos","year":"2013","unstructured":"De Vos A, Van de Velde H, Bocken G et al (2013) Does intracytoplasmic morphologically selected sperm injection improve embryo development? A randomized sibling-oocyte study. Hum Reprod 28:617\u2013626","journal-title":"Hum Reprod"},{"key":"10_CR001044","doi-asserted-by":"crossref","first-page":"1552","DOI":"10.1093\/humrep\/15.7.1552","volume":"15","author":"ET Donnelly","year":"2000","unstructured":"Donnelly ET, O'Connell M, McClure N et al (2000) Differences in nuclear DNA fragmentation and mitochondrial integrity of semen and prepared human spermatozoa. Hum Reprod 15:1552\u20131561","journal-title":"Hum Reprod"},{"key":"10_CR001045","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1093\/humrep\/16.6.1191","volume":"16","author":"ET Donnelly","year":"2001","unstructured":"Donnelly ET, Steele EK, McClure N et al (2001) Assessment of DNA integrity and morphology of ejaculated spermatozoa from fertile and infertile men before and after cryopreservation. Hum Reprod 16:1191\u20131199","journal-title":"Hum Reprod"},{"key":"10_CR001046","doi-asserted-by":"crossref","first-page":"3122","DOI":"10.1093\/humrep\/17.12.3122","volume":"17","author":"EH Duran","year":"2002","unstructured":"Duran EH, Morshedi M, Taylor S et al (2002) Sperm DNA quality predicts intrauterine insemination outcome: a prospective cohort study. Hum Reprod 17:3122\u20133128","journal-title":"Hum Reprod"},{"key":"10_CR001047","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.rbmo.2010.09.004","volume":"22","author":"T Ebner","year":"2011","unstructured":"Ebner T, Shebl O, Moser M et al (2011) Easy sperm processing technique allowing exclusive accumulation and later usage of DNA-strandbreak-free spermatozoa. Reprod Biomed Online 22:37\u201343","journal-title":"Reprod Biomed Online"},{"issue":"1","key":"10_CR001048","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1111\/j.1439-0272.2011.01266.x","volume":"44","author":"T Ebner","year":"2012","unstructured":"Ebner T, Filicori M, Tews G, Parmegiani L (2012) A plea for a more physiological ICSI. Andrologia 44(1):2\u201319","journal-title":"Andrologia"},{"key":"10_CR001049","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/S1472-6483(10)60003-X","volume":"18","author":"M Enciso","year":"2009","unstructured":"Enciso M, Sarasa J, Agarwal A et al (2009) A two-tailed Comet assay for assessing DNA damage in spermatozoa. Reprod Biomed Online 18:609\u2013616","journal-title":"Reprod Biomed Online"},{"key":"10_CR001050","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1093\/humrep\/14.4.1039","volume":"14","author":"DP Evenson","year":"1999","unstructured":"Evenson DP, Jost LK, Marshall D et al (1999) Utility of the sperm chromatin structure assay as a diagnostic and prognostic tool in the human fertility clinic. Hum Reprod 14:1039\u20131049","journal-title":"Hum Reprod"},{"key":"10_CR001051","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1002\/j.1939-4640.2002.tb02599.x","volume":"23","author":"DP Evenson","year":"2002","unstructured":"Evenson DP, Larson KL, Jost LK (2002) Sperm chromatin structure assay: its clinical use for detecting sperm DNA fragmentation in male infertility and comparisons with other techniques. J Androl 23:25\u201343","journal-title":"J Androl"},{"key":"10_CR001052","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1002\/j.1939-4640.2003.tb02748.x","volume":"24","author":"JL Fernandez","year":"2003","unstructured":"Fernandez JL, Muriel L, Rivero MT et al (2003) The sperm chromatin dispersion test: a simple method for the determination of sperm DNA fragmentation. J Androl 24:59\u201366","journal-title":"J Androl"},{"key":"10_CR001053","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1095\/biolreprod.107.065623","volume":"78","author":"R Fernandez-Gonzalez","year":"2008","unstructured":"Fernandez-Gonzalez R, Moreira PN, Perez-Crespo M (2008) Long-term effects of mouse intracytoplasmic sperm injection with DNA-fragmented sperm on health and behavior of adult offspring. Biol Reprod 78:761\u2013772","journal-title":"Biol Reprod"},{"key":"10_CR001054","doi-asserted-by":"crossref","first-page":"2646","DOI":"10.1093\/humrep\/den330","volume":"23","author":"SD Fleming","year":"2008","unstructured":"Fleming SD, Ilad RS, Griffin AM et al (2008) Prospective controlled trial of an electrophoretic method of sperm preparation for assisted reproduction: comparison with density gradient centrifugation. Hum Reprod 23:2646\u20132651","journal-title":"Hum Reprod"},{"key":"10_CR001055","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/S1472-6483(10)60291-X","volume":"17","author":"JG Franco Jr","year":"2008","unstructured":"Franco JG Jr, Baruffi RL, Mauri AL et al (2008) Significance of large nuclear vacuoles in human spermatozoa: implications for ICSI. Reprod Biomed Online 17:42\u201345","journal-title":"Reprod Biomed Online"},{"key":"10_CR001056","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1016\/j.fertnstert.2008.10.051","volume":"93","author":"DB French","year":"2010","unstructured":"French DB, Sabanegh ES Jr, Goldfarb J et al (2010) Does severe teratozoospermia affect blastocyst formation, live birth rate, and other clinical outcome parameters in ICSI cycles? Fertil Steril 93:1097\u20131103","journal-title":"Fertil Steril"},{"key":"10_CR001057","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.fertnstert.2007.02.022","volume":"89","author":"N Frydman","year":"2008","unstructured":"Frydman N, Prisant N, Hesters L et al (2008) Adequate ovarian follicular status does not prevent the decrease in pregnancy rates associated with high sperm DNA fragmentation. Fertil Steril 89:92\u201397","journal-title":"Fertil Steril"},{"key":"10_CR001058","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.1093\/humrep\/deh233","volume":"19","author":"L Gandini","year":"2004","unstructured":"Gandini L, Lombardo F, Paoli D et al (2004) Full-term pregnancies achieved with ICSI despite high levels of sperm chromatin damage. Hum Reprod 19:1409\u20131417","journal-title":"Hum Reprod"},{"key":"10_CR001059","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1016\/S1472-6483(10)60307-0","volume":"17","author":"A Garolla","year":"2008","unstructured":"Garolla A, Fortini D, Menegazzo M et al (2008) High-power microscopy for selecting spermatozoa for ICSI by physiological status. Reprod Biomed Online 17:610\u2013616","journal-title":"Reprod Biomed Online"},{"key":"10_CR001060","doi-asserted-by":"crossref","first-page":"1404","DOI":"10.1016\/S0015-0282(03)02212-X","volume":"80","author":"A Giwercman","year":"2003","unstructured":"Giwercman A, Richthoff J, Hj\u00f8llund H et al (2003) Correlation between sperm motility and sperm chromatin structure assay parameters. Fertil Steril 80:1404\u20131412","journal-title":"Fertil Steril"},{"key":"10_CR001061","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1006\/excr.1993.1182","volume":"207","author":"W Gorczyca","year":"1993","unstructured":"Gorczyca W, Traganos F, Jesionowska H et al (1993) Presence of DNA strand breaks and increased sensitivity of DNA in situ to denaturation in abnormal human sperm cells: analogy to apoptosis of somatic cells. Exp Cell Res 207:202\u2013205","journal-title":"Exp Cell Res"},{"key":"10_CR001062","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1093\/humrep\/deh590","volume":"20","author":"E Greco","year":"2005","unstructured":"Greco E, Scarselli F, Iacobelli M et al (2005) Efficient treatment of infertility due to sperm DNA damage by ICSI with testicular spermatozoa. Hum Reprod 20:226\u2013230","journal-title":"Hum Reprod"},{"key":"10_CR001063","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/S1472-6483(10)60975-3","volume":"12","author":"A Hazout","year":"2006","unstructured":"Hazout A, Dumont-Hassan M, Junca AM et al (2006) High-magnification ICSI overcomes paternal effect resistant to conventional ICSI. Reprod Biomed Online 12:19\u201325","journal-title":"Reprod Biomed Online"},{"key":"10_CR001064","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1016\/j.fertnstert.2003.09.044","volume":"81","author":"R Henkel","year":"2004","unstructured":"Henkel R, Hajimohammad M, Stalf T et al (2004) Influence of deoxyribonucleic acid damage on fertilization and pregnancy. Fertil Steril 81:965\u2013972","journal-title":"Fertil Steril"},{"key":"10_CR001065","doi-asserted-by":"crossref","first-page":"2417","DOI":"10.1093\/humrep\/dep207","volume":"24","author":"E Heytens","year":"2009","unstructured":"Heytens E, Parrington J, Coward K et al (2009) Reduced amounts and abnormal forms of phospholipase C zeta (PLC\u03b6) in spermatozoa from infertile men. Hum Reprod 24:2417\u20132428","journal-title":"Hum Reprod"},{"key":"10_CR001066","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1034\/j.1600-0412.1999.780412.x","volume":"78","author":"E H\u00f8st","year":"1999","unstructured":"H\u00f8st E, Lindenberg S, Kahn JA et al (1999) DNA strand breaks in human sperm cells: a comparison between men with normal and oligozoospermic sperm samples. Acta Obstet Gynecol Scand 78:336\u2013339","journal-title":"Acta Obstet Gynecol Scand"},{"key":"10_CR001067","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1034\/j.1600-0412.2000.079003189.x","volume":"79","author":"E H\u00f8st","year":"2000","unstructured":"H\u00f8st E, Lindenberg S, Smidt-Jensen S (2000a) DNA strand breaks in human spermatozoa: correlation with fertilization in vitro in oligozoospermic men and in men with unexplained infertility. Acta Obstet Gynecol Scand 79:189\u2013193","journal-title":"Acta Obstet Gynecol Scand"},{"key":"10_CR001068","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1034\/j.1600-0412.2000.079003189.x","volume":"79","author":"E H\u00f8st","year":"2000","unstructured":"H\u00f8st E, Lindenberg S, Smidt-Jensen S (2000b) The role of DNA strand breaks in human spermatozoa used for IVF and ICSI. Acta Obstet Gynecol Scand 79:559\u2013563","journal-title":"Acta Obstet Gynecol Scand"},{"key":"10_CR001069","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.fertnstert.2004.08.042","volume":"84","author":"CC Huang","year":"2005","unstructured":"Huang CC, Lin DP, Tsao HM et al (2005) Sperm DNA fragmentation negatively correlates with velocity and fertilization rates but might not affect pregnancy rates. Fertil Steril 84:130\u2013140","journal-title":"Fertil Steril"},{"key":"10_CR001070","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1093\/molehr\/2.8.613","volume":"2","author":"CM Hughes","year":"1996","unstructured":"Hughes CM, Lewis SE, McKelvey-Martin VJ et al (1996) A comparison of baseline and induced DNA damage in human spermatozoa from fertile and infertile men, using a modified comet assay. Mol Hum Reprod 2:613\u2013619","journal-title":"Mol Hum Reprod"},{"issue":"1","key":"10_CR001071","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.fertnstert.2012.11.024","volume":"99","author":"CK Humm","year":"2013","unstructured":"Humm CK, Sakkas D (2013) Role of increased male age in IVF and egg donation: is sperm DNA fragmentation responsible? Fertil Steril 99(1):30\u201336","journal-title":"Fertil Steril"},{"key":"10_CR001072","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1095\/biolreprod55.1.80","volume":"55","author":"GR Hunnicutt","year":"1996","unstructured":"Hunnicutt GR, Primakoff P, Myles DG (1996) Sperm surface protein PH-20 is bifunctional: one activity is a hyaluronidase and a second, distinct activity is required in secondary sperm-zona binding. Biol Reprod 55:80\u201386","journal-title":"Biol Reprod"},{"key":"10_CR001073","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1002\/mrd.1080340309","volume":"34","author":"G Huszar","year":"1993","unstructured":"Huszar G, Vigue L (1993) Incomplete development of human spermatozoa is associated with increased creatine phosphokinase concentration and abnormal head morphology. Mol Reprod Dev 34:292\u2013298","journal-title":"Mol Reprod Dev"},{"key":"10_CR001074","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1095\/biolreprod63.3.925","volume":"63","author":"G Huszar","year":"2000","unstructured":"Huszar G, Stone K, Dix D et al (2000) Putative creatine kinase M-isoform in human sperm is identified as the 70-kilodalton heat shock protein HspA2. Biol Reprod 63:925\u2013932","journal-title":"Biol Reprod"},{"issue":"3","key":"10_CR001075","doi-asserted-by":"crossref","first-page":"1616","DOI":"10.1016\/S0015-0282(03)00402-3","volume":"79","author":"G Huszar","year":"2003","unstructured":"Huszar G, Ozenci CC, Cayli S et al (2003) Hyaluronic acid binding by human sperm indicates cellular maturity, viability, and unreacted acrosomal status. Fertil Steril 79(3):1616\u20131624","journal-title":"Fertil Steril"},{"key":"10_CR001076","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1016\/S1472-6483(10)61060-7","volume":"14","author":"G Huszar","year":"2007","unstructured":"Huszar G, Jakab A, Sakkas D et al (2007) Fertility testing and ICSI sperm selection by hyaluronic acid binding: clinical and genetic aspects. Reprod Biomed Online 14:650\u2013663","journal-title":"Reprod Biomed Online"},{"key":"10_CR001077","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1002\/j.1939-4640.2000.tb03273.x","volume":"21","author":"DS Irvine","year":"2000","unstructured":"Irvine DS, Twigg JP, Gordon EL, Fulton N, Milne PA, Aitken RJ (2000) DNA integrity in human spermatozoa: relationships with semen quality. J Androl 21:33\u201344","journal-title":"J Androl"},{"key":"10_CR001078","doi-asserted-by":"crossref","first-page":"2626","DOI":"10.1016\/j.fertnstert.2010.04.049","volume":"94","author":"RE Jackson","year":"2010","unstructured":"Jackson RE, Bormann CL, Hassun PA et al (2010) Effects of semen storage and separation techniques on sperm DNA fragmentation. Fertil Steril 94:2626\u20132630","journal-title":"Fertil Steril"},{"key":"10_CR001079","doi-asserted-by":"crossref","first-page":"1665","DOI":"10.1016\/j.fertnstert.2005.05.068","volume":"84","author":"A Jakab","year":"2005","unstructured":"Jakab A, Sakkas D, Delpiano E et al (2005) Intracytoplasmic sperm injection: a novel selection method for sperm with normal frequency of chromosomal aneuploidies. Fertil Steril 84: 1665\u20131673","journal-title":"Fertil Steril"},{"key":"10_CR001080","doi-asserted-by":"crossref","first-page":"1292","DOI":"10.1093\/humrep\/del507","volume":"22","author":"G Joly- Helas","year":"2007","unstructured":"Joly- Helas G, de La Rochebrochard C, Mousset-Sim\u00e9on N et al (2007) Complex chromosomal rearrangement and intracytoplasmic sperm injection: a case report. Hum Reprod 22:1292\u20131297","journal-title":"Hum Reprod"},{"key":"10_CR001081","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1007\/s10815-012-9710-5","volume":"29","author":"A Junca","year":"2012","unstructured":"Junca A, Marti BG, Tosti E et al (2012) Sperm nucleus decondensation, hyaluronic acid (HA) binding and oocyte activation capacity: different markers of sperm immaturity? Case reports. J Assist Reprod Genet 29:353\u2013365","journal-title":"J Assist Reprod Genet"},{"key":"10_CR001082","first-page":"97","volume":"4","author":"T Kasai","year":"2002","unstructured":"Kasai T, Ogawa K, Mizuno K et al (2002) Relationship between sperm mitochondrial membrane potential, sperm motility, and fertility potential. Asian J Androl 4:97\u2013103","journal-title":"Asian J Androl"},{"key":"10_CR001083","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/j.rbmo.2010.11.020","volume":"22","author":"C Kennedy","year":"2011","unstructured":"Kennedy C, Ahlering P, Rodriguez H et al (2011) Sperm chromatin structure correlates with spontaneous abortion and multiple pregnancy rates in assisted reproduction. Reprod Biomed Online 22:272\u2013276","journal-title":"Reprod Biomed Online"},{"key":"10_CR001084","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/j.fertnstert.2010.08.014","volume":"95","author":"JW Kim","year":"2011","unstructured":"Kim JW, Chang EM, Song SH et al (2011) Complex chromosomal rearrangements in infertile males: complexity of rearrangement affects spermatogenesis. Fertil Steril 95:349\u2013352","journal-title":"Fertil Steril"},{"key":"10_CR001085","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1007\/s10815-010-9479-3","volume":"28","author":"P Kovacs","year":"2011","unstructured":"Kovacs P, Kovats T, Sajgo A et al (2011) The role of hyaluronic acid binding assay in choosing the fertilization method for patients undergoing IVF for unexplained infertility. J Assist Reprod Genet 28:49\u201354","journal-title":"J Assist Reprod Genet"},{"key":"10_CR001086","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1093\/humrep\/16.6.1209","volume":"16","author":"E Kovanci","year":"2001","unstructured":"Kovanci E, Kovacs T, Moretti E et al (2001) FISH assessment of aneuploidy frequencies in mature and immature human spermatozoa classified by the absence or presence of cytoplasmic retention. Hum Reprod 16:1209\u20131217","journal-title":"Hum Reprod"},{"key":"10_CR001087","doi-asserted-by":"crossref","first-page":"1118","DOI":"10.1016\/S0015-0282(16)49891-2","volume":"46","author":"TF Kruger","year":"1986","unstructured":"Kruger TF, Menkveld R, Stander FS et al (1986) Sperm morphologic features as a prognostic factor in in vitro fertilization. Fertil Steril 46:1118\u20131123","journal-title":"Fertil Steril"},{"key":"10_CR001088","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/S0015-0282(16)59660-5","volume":"49","author":"TF Kruger","year":"1988","unstructured":"Kruger TF, Acosta AA, Simmons KF et al (1988) Predictive value of abnormal sperm morphology in in vitro fertilization. Fertil Steril 49:112\u2013117","journal-title":"Fertil Steril"},{"key":"10_CR001089","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1016\/S0015-0282(03)01116-6","volume":"80","author":"KL Larson-Cook","year":"2003","unstructured":"Larson-Cook KL, Brannian JD, Hansen KA et al (2003) Relationship between the outcomes of assisted reproductive techniques and sperm DNA fragmentation as measured by the sperm chromatin structure assay. Fertil Steril 80:895\u2013902","journal-title":"Fertil Steril"},{"key":"10_CR001090","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1093\/humrep\/deq009","volume":"25","author":"TH Lee","year":"2010","unstructured":"Lee TH, Liu CH, Shih YT et al (2010) Magnetic-activated cell sorting for sperm preparation reduces spermatozoa with apoptotic markers and improves the acrosome reaction in couples with unexplained infertility. Hum Reprod 25:839\u2013846","journal-title":"Hum Reprod"},{"key":"10_CR001091","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1093\/humrep\/dem257","volume":"23","author":"L Leunens","year":"2008","unstructured":"Leunens L, Celestin-Westreich S, Bonduelle M et al (2008) Follow-up of cognitive and motor development of 10-year-old singleton children born after ICSI compared with spontaneously conceived children. Hum Reprod 23:105\u2013111","journal-title":"Hum Reprod"},{"key":"10_CR001092","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1007\/s10815-006-9066-9","volume":"23","author":"Z Li","year":"2006","unstructured":"Li Z, Wang L, Cai J et al (2006) Correlation of sperm DNA damage with IVF and ICSI outcomes: a systematic review and meta-analysis. J Assist Reprod Genet 23:367\u2013376","journal-title":"J Assist Reprod Genet"},{"key":"10_CR001093","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1016\/j.fertnstert.2007.06.018","volume":"90","author":"MH Lin","year":"2008","unstructured":"Lin MH, Kuo-Kuang Lee R et al (2008) Sperm chromatin structure assay parameters are not related to fertilization rates, embryo quality, and pregnancy rates in in vitro fertilization and intracytoplasmic sperm injection, but might be related to spontaneous abortion rates. Fertil Steril 90:352\u2013359","journal-title":"Fertil Steril"},{"key":"10_CR001094","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1016\/j.fertnstert.2010.09.015","volume":"95","author":"F Liu","year":"2011","unstructured":"Liu F, Qiu Y, Zou Y et al (2011) Use of zona pellucida-bound sperm for intracytoplasmic sperm injection produces higher embryo quality and implantation than conventional intracytoplasmic sperm injection. Fertil Steril 95:815\u2013818","journal-title":"Fertil Steril"},{"key":"10_CR001095","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1093\/humrep\/deg202","volume":"18","author":"S Loft","year":"2003","unstructured":"Loft S, Kold-Jensen T, Hjollund NH et al (2003) Oxidative DNA damage in human sperm influences time to pregnancy. Hum Reprod 18:1265\u20131272","journal-title":"Hum Reprod"},{"key":"10_CR001096","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1016\/S0015-0282(97)00536-0","volume":"69","author":"S Lopes","year":"1998","unstructured":"Lopes S, Sun JG, Jurisicova A et al (1998) Sperm deoxyribonucleic acid fragmentation is increased in poor-quality semen samples and correlates with failed fertilization in intracytoplasmic sperm injection. Fertil Steril 69:528\u2013532","journal-title":"Fertil Steril"},{"key":"10_CR001097","doi-asserted-by":"crossref","first-page":"2141","DOI":"10.1016\/j.fertnstert.2009.12.030","volume":"94","author":"R Mahfouz","year":"2010","unstructured":"Mahfouz R, Sharma R, Thiyagarajan A et al (2010) Semen characteristics and sperm DNA fragmentation in infertile men with low and high levels of seminal reactive oxygen species. Fertil Steril 94:2141\u20132146","journal-title":"Fertil Steril"},{"key":"10_CR001098","doi-asserted-by":"crossref","first-page":"481","DOI":"10.2164\/jandrol.106.002105","volume":"28","author":"DE Marchesi","year":"2007","unstructured":"Marchesi DE, Feng HL (2007) Sperm DNA integrity from sperm to egg. J Androl 28:481\u2013489","journal-title":"J Androl"},{"key":"10_CR001099","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.ejogrb.2010.05.003","volume":"151","author":"DE Marchesi","year":"2010","unstructured":"Marchesi DE, Biederman H, Ferrara S et al (2010) The effect of semen processing on sperm DNA integrity: comparison of two techniques using the novel Toluidine Blue Assay. Eur J Obstet Gynecol Reprod Biol 151:176\u2013180","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"10_CR00100183","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.ejogrb.2010.01.004","volume":"150","author":"AL Mauri","year":"2010","unstructured":"Mauri AL, Petersen CG, Oliveire JB et al (2010) Comparison of day 2 embryo quality after conventional ICSI versus intracytoplasmic morphologically selected sperm injection (IMSI) using sibling oocytes. Eur J Obstet Gynecol Reprod Biol 150:42\u201346","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"10_CR0010100","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1023\/B:JARG.0000040237.47026.0f","volume":"21","author":"JM Morrell","year":"2004","unstructured":"Morrell JM, Moffatt O, Sakkas D et al (2004) Reduced senescence and retained nuclear DNA integrity in human spermatozoa prepared by density gradient centrifugation. J Assist Reprod Genet 21:217\u2013222","journal-title":"J Assist Reprod Genet"},{"key":"10_CR0010101","first-page":"109","volume":"37","author":"S McPherson","year":"1993","unstructured":"McPherson S, Longo FJ (1993) Chromatin structure-function alterations during mammalian spermatogenesis: DNA nicking and repair in elongating spermatids. Eur J Histochem 37:109\u2013128","journal-title":"Eur J Histochem"},{"key":"10_CR0010102","unstructured":"Menezo Y, Nicollet B (2004) Replacement of PVP by hyaluronate (SpermSlow\u2122) in ICSI \u2013 impact on outcome. Abstract of 18th world congress on fertility and sterility IFFS"},{"issue":"1","key":"10_CR0010103","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/j.fertnstert.2010.07.900","volume":"94","author":"Y Menezo","year":"2010","unstructured":"Menezo Y, Junca AM, Dumont-Hassan M et al (2010) \u201cPhysiologic\u201d' (hyaluronic acid-carried) ICSI results in the same embryo quality and pregnancy rates as with the use of potentially toxic polyvinylpyrrolidone (PVP). Fertil Steril 94(1):232","journal-title":"Fertil Steril"},{"key":"10_CR0010104","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.fertnstert.2010.05.055","volume":"95","author":"M Meseguer","year":"2011","unstructured":"Meseguer M, Santiso R, Garrido N et al (2011) Effect of sperm DNA fragmentation on pregnancy outcome depends on oocyte quality. Fertil Steril 95:124\u2013128","journal-title":"Fertil Steril"},{"key":"10_CR0010105","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1093\/humrep\/17.4.990","volume":"17","author":"ID Morris","year":"2002","unstructured":"Morris ID, Ilott S, Dixon L et al (2002) The spectrum of DNA damage in human sperm assessed by single cell gel electrophoresis (Comet assay) and its relationship to fertilization and embryo development. Hum Reprod 17:990\u2013998","journal-title":"Hum Reprod"},{"key":"10_CR0010106","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1002\/j.1939-4640.2003.tb02670.x","volume":"24","author":"M Muratori","year":"2003","unstructured":"Muratori M, Maggi M, Spinelli S et al (2003) Spontaneous DNA fragmentation in swim-up selected human spermatozoa during long term incubation. J Androl 24:253\u2013262","journal-title":"J Androl"},{"key":"10_CR0010107","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/j.fertnstert.2005.07.1327","volume":"85","author":"L Muriel","year":"2006","unstructured":"Muriel L, Garrido N, Fern\u00e1ndez JL et al (2006) Value of the sperm deoxyribonucleic acid fragmentation level, as measured by the sperm chromatin dispersion test, in the outcome of in vitro fertilization and intracytoplasmic sperm injection. Fertil Steril 85:371\u2013383","journal-title":"Fertil Steril"},{"issue":"l3","key":"10_CR0010108","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/S1472-6483(10)60283-0","volume":"19","author":"M Nadalini","year":"2009","unstructured":"Nadalini M, Tarozzi N, Distratis V et al (2009) Impact of intracytoplasmic morphologically selected sperm injection on assisted reproduction outcome a review. Reprod Biomed Online 19(l3):45\u201355","journal-title":"Reprod Biomed Online"},{"key":"10_CR0010109","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1007\/s10815-008-9223-4","volume":"25","author":"MH Nasr-Esfahani","year":"2008","unstructured":"Nasr-Esfahani MH, Razavi S, Vahdati AA et al (2008) Evaluation of sperm selection procedure based on hyaluronic acid binding ability on ICSI outcome. J Assist Reprod Genet 25:197\u2013203","journal-title":"J Assist Reprod Genet"},{"key":"10_CR0010110","doi-asserted-by":"crossref","first-page":"2647","DOI":"10.1093\/humrep\/deq200","volume":"25","author":"P Navarro-Costa","year":"2010","unstructured":"Navarro-Costa P, Nogueira P, Carvalho M et al (2010) Incorrect DNA methylation of the DAZL promoter CpG island associates with defective human sperm. Hum Reprod 25:2647\u20132654","journal-title":"Hum Reprod"},{"key":"10_CR0010111","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1016\/j.rbmo.2009.07.002","volume":"19","author":"M Nijs","year":"2009","unstructured":"Nijs M, Creemers E, Cox A et al (2009) Chromomycin A3 staining, sperm chromatin structure assay and hyaluronic acid binding assay as predictors for assisted reproductive outcome. Reprod Biomed Online 19:671\u2013684","journal-title":"Reprod Biomed Online"},{"key":"10_CR0010112","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1111\/j.1439-0272.2009.00992.x","volume":"42","author":"M Nijs","year":"2010","unstructured":"Nijs M, Creemers E, Cox A et al (2010) Relationship between hyaluronic acid binding assay and outcome in ART: a pilot study. Andrologia 42:291\u2013296","journal-title":"Andrologia"},{"key":"10_CR0010113","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1016\/S1472-6483(10)60088-0","volume":"18","author":"JB Oliveira","year":"2009","unstructured":"Oliveira JB, Massaro FC, Mauri AL et al (2009) Motile sperm organelle morphology examination is stricter than Tygerberg criteria. Reprod Biomed Online 18:320\u2013326","journal-title":"Reprod Biomed Online"},{"key":"10_CR0010114","doi-asserted-by":"crossref","first-page":"1912","DOI":"10.1093\/humrep\/16.9.1912","volume":"16","author":"M Ollero","year":"2001","unstructured":"Ollero M, Gil-Guzman E, Lopez MC et al (2001) Characterization of subsets of human spermatozoa at different stages of maturation: implications in the diagnosis and treatment of male infertility. Hum Reprod 16:1912\u20131921","journal-title":"Hum Reprod"},{"key":"10_CR0010115","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/S1472-6483(10)60710-9","volume":"15","author":"B Ozmen","year":"2007","unstructured":"Ozmen B, Caglar GS, Koster F et al (2007) Relationship between sperm DNA damage, induced acrosome reaction and viability in ICSI patients. Reprod Biomed Online 15:208\u2013214","journal-title":"Reprod Biomed Online"},{"issue":"8810","key":"10_CR0010116","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/0140-6736(92)92425-F","volume":"340","author":"G Palermo","year":"1992","unstructured":"Palermo G, Joris H, Devroey P et al (1992) Pregnancies after intracytoplasmic injection of single spermatozoon into an oocyte. Lancet 340(8810):17\u201318","journal-title":"Lancet"},{"key":"10_CR0010117","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1016\/j.fertnstert.2009.03.033","volume":"93","author":"L Parmegiani","year":"2010","unstructured":"Parmegiani L, Cognigni GE, Bernardi S et al (2010a) \u201cPhysiologic ICSI\u201d: hyaluronic acid (HA) favors selection of spermatozoa without DNA fragmentation and with normal nucleus, resulting in improvement of embryo quality. Fertil Steril 93:598\u2013604","journal-title":"Fertil Steril"},{"key":"10_CR0010118","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1007\/s10815-009-9380-0","volume":"27","author":"L Parmegiani","year":"2010","unstructured":"Parmegiani L, Cognigni GE, Ciampaglia W et al (2010b) Efficiency of hyaluronic acid (HA) sperm selection. J Assist Reprod Genet 27:13\u201316","journal-title":"J Assist Reprod Genet"},{"key":"10_CR0010119","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/j.rbmo.2009.12.020","volume":"20","author":"L Parmegiani","year":"2010","unstructured":"Parmegiani L, Cognigni GE, Filicori M (2010c) Risks in injecting hyaluronic acid non-bound spermatozoa. Reprod Biomed Online 20:437\u2013438","journal-title":"Reprod Biomed Online"},{"key":"10_CR0010120","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1016\/j.fertnstert.2012.05.043","volume":"98","author":"L Parmegiani","year":"2012","unstructured":"Parmegiani L, Cognigni GE, Bernardi S et al (2012a) Comparison of two ready-to-use systems designed for sperm-hyaluronic acid binding selection before intracytoplasmic sperm injection: PICSI vs. sperm slow: a prospective, randomized trial. Fertil Steril 98:632\u2013637","journal-title":"Fertil Steril"},{"key":"10_CR0010121","doi-asserted-by":"publisher","first-page":"99","DOI":"10.5772\/39227","volume-title":"Advances in embryo transfer","author":"L Parmegiani","year":"2012","unstructured":"Parmegiani L, Cognigni GE, Filicori M (2012b) New advances in intracytoplasmic sperm injection (ICSI). In: Bin W (ed) Advances in embryo transfer. InTech, New York, pp 99\u2013115. doi:10.5772\/39227"},{"key":"10_CR0010122","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1016\/j.fertnstert.2005.02.032","volume":"84","author":"JF Payne","year":"2005","unstructured":"Payne JF, Raburn DJ, Couchman GM et al (2005) Redefining the relationship between sperm deoxyribonucleic acid fragmentation as measured by the sperm chromatin structure assay and outcomes of assisted reproductive techniques. Fertil Steril 84:356\u2013364","journal-title":"Fertil Steril"},{"key":"10_CR0010123","doi-asserted-by":"crossref","first-page":"1589","DOI":"10.1016\/j.fertnstert.2007.01.069","volume":"88","author":"S Peer","year":"2007","unstructured":"Peer S, Eltes F, Berkovitz A, Yehuda R et al (2007) Is fine morphology of the human sperm nuclei affected by in vitro incubation at 37 degrees C? Fertil Steril 88:1589\u20131594","journal-title":"Fertil Steril"},{"key":"10_CR0010124","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1093\/humrep\/deq297","volume":"26","author":"A Perdrix","year":"2011","unstructured":"Perdrix A, Travers A, Chelli MH et al (2011) Assessment of acrosome and nuclear abnormalities in human spermatozoa with large vacuoles. Hum Reprod 26:47\u201358","journal-title":"Hum Reprod"},{"issue":"351","key":"10_CR0010125","first-page":"e16","volume":"94","author":"E Polak de Fried","year":"2010","unstructured":"Polak de Fried E, Denaday F (2010) Single and twin ongoing pregnancies in two cases of previous ART failure after ICSI performed with sperm sorted using annexin V microbeads. Fertil Steril 94(351):e16","journal-title":"Fertil Steril"},{"key":"10_CR0010126","doi-asserted-by":"crossref","first-page":"1233","DOI":"10.1016\/j.fertnstert.2012.11.048","volume":"99","author":"B Pregl Breznik","year":"2013","unstructured":"Pregl Breznik B, Kova\u010di\u010d B, Vlaisavljevi\u0107 V (2013) Are sperm DNA fragmentation, hyperactivation, and hyaluronan-binding ability predictive for fertilization and embryo development in in vitro fertilization and intracytoplasmic sperm injection? Fertil Steril 99:1233\u20131241","journal-title":"Fertil Steril"},{"key":"10_CR0010127","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/S1472-6483(10)60253-2","volume":"18","author":"P Prinosilova","year":"2009","unstructured":"Prinosilova P, Kruger T, Sati L et al (2009) Selectivity of hyaluronic acid binding for spermatozoa with normal Tygerberg strict morphology. Reprod Biomed Online 18:177\u2013183","journal-title":"Reprod Biomed Online"},{"key":"10_CR0010128","doi-asserted-by":"crossref","first-page":"1703","DOI":"10.1093\/humrep\/16.8.1703","volume":"16","author":"L Ramos","year":"2001","unstructured":"Ramos L, Wetzels AM (2001) Low rates of DNA fragmentation in selected motile human spermatozoa assessed by the TUNEL assay. Hum Reprod 16:1703\u20131707","journal-title":"Hum Reprod"},{"key":"10_CR0010129","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1016\/j.rbmo.2009.12.004","volume":"20","author":"VY Rawe","year":"2010","unstructured":"Rawe VY, Boudri HU, Alvarez Sed\u00f3 C et al (2010) Healthy baby born after reduction of sperm DNA fragmentation using cell sorting before ICSI. Reprod Biomed Online 20:320\u2013323","journal-title":"Reprod Biomed Online"},{"key":"10_CR0010130","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1111\/j.1439-0272.2009.00948.x","volume":"42","author":"SH Razavi","year":"2010","unstructured":"Razavi SH, Nasr-Esfahani MH, Deemeh MR et al (2010) Evaluation of zeta and HA-binding methods for selection of spermatozoa with normal morphology, protamine content and DNA integrity. Andrologia 42:13\u201319","journal-title":"Andrologia"},{"key":"10_CR0010131","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1038\/35015097","volume":"405","author":"C Richardson","year":"2000","unstructured":"Richardson C, Jasin M (2000) Frequent chromosomal translocations induced by DNA double-strand breaks. Nature 405:697\u2013700","journal-title":"Nature"},{"key":"10_CR0010132","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1095\/biolreprod.105.046607","volume":"74","author":"T Said","year":"2006","unstructured":"Said T, Agarwal A, Grunewald S et al (2006) Selection of nonapoptotic spermatozoa as a new tool for enhancing assisted reproduction outcomes: an in vitro model. Biol Reprod 74:530\u2013537","journal-title":"Biol Reprod"},{"key":"10_CR0010133","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1016\/j.fertnstert.2009.10.046","volume":"93","author":"D Sakkas","year":"2010","unstructured":"Sakkas D, Alvarez JG (2010) Sperm DNA fragmentation: mechanisms of origin, impact on reproductive outcome, and analysis. Fertil Steril 93:1027\u20131036","journal-title":"Fertil Steril"},{"key":"10_CR0010134","first-page":"205","volume-title":"Genetics of human male infertility","author":"D Sakkas","year":"1997","unstructured":"Sakkas D, Bianchi PG, Manicardi GC (1997) Chromatin packaging anomalies and DNA damage in human sperm: their possible implications in the treatment of male factor infertility. In: Barratt C, De Jonge C, Mortimer D, Parinaud J (eds) Genetics of human male infertility. Editions EDK, Paris, pp 205\u2013221"},{"key":"10_CR0010183","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1080\/1464727002000198651","volume":"3","author":"D Sakkas","year":"2000","unstructured":"Sakkas D, Manicardi G, Bizzaro D et al (2000) Possible consequences of performing intracytoplasmic sperm Injection (ICSI) with sperm possessing nuclear DNA damage. Hum Fertil 3:26\u201330","journal-title":"Hum Fertil"},{"key":"10_CR0010135","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/j.fertnstert.2012.04.040","volume":"98","author":"SR Salian","year":"2012","unstructured":"Salian SR, Kalthur G, Uppangala S et al (2012) Frozen-thawed spermatozoa from oligozoospermic ejaculates are susceptible to in situ DNA fragmentation in polyvinylpyrrolidone-based sperm-immobilization medium. Fertil Steril 98:321\u2013325","journal-title":"Fertil Steril"},{"issue":"Suppl 1","key":"10_CR0010136","first-page":"i200","volume":"20","author":"M Sanchez","year":"2005","unstructured":"Sanchez M, Aran B, Blanco J et al (2005) Preliminary clinical and FISH results on hyaluronic acid sperm selection to improve ICSI. Hum Reprod 20(Suppl 1):i200","journal-title":"Hum Reprod"},{"key":"10_CR0010137","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.mrfmmm.2012.03.006","volume":"734","author":"R Santiso","year":"2012","unstructured":"Santiso R, Tamayo M, Gos\u00e1lvez J et al (2012) DNA fragmentation dynamics allows the assessment of cryptic sperm damage in human: evaluation of exposure to ionizing radiation, hyperthermia, acidic pH and nitric oxide. Mutat Res 734:41\u201349","journal-title":"Mutat Res"},{"key":"10_CR0010138","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1093\/molehr\/gap049","volume":"15","author":"H Schatten","year":"2009","unstructured":"Schatten H, Sun QY (2009) The role of centrosomes in mammalian fertilization and its significance for ICSI. Mol Hum Reprod 15:531\u2013538","journal-title":"Mol Hum Reprod"},{"key":"10_CR0010139","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1016\/j.fertnstert.2003.12.039","volume":"82","author":"E Seli","year":"2004","unstructured":"Seli E, Gardner DK, Schoolcraft WB et al (2004) Extent of nuclear DNA damage in ejaculated spermatozoa impacts on blastocyst development after in vitro fertilization. Fertil Steril 82:378\u2013383","journal-title":"Fertil Steril"},{"key":"10_CR0010141","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1093\/molehr\/3.10.847","volume":"3","author":"JP Siffroi","year":"1997","unstructured":"Siffroi JP, Benzacken B, Straub B et al (1997) Assisted reproductive technology and complex chromosomal rearrangements: the limits of ICSI. Mol Hum Reprod 3:847\u2013851","journal-title":"Mol Hum Reprod"},{"key":"10_CR0010142","doi-asserted-by":"crossref","first-page":"1594","DOI":"10.1093\/humrep\/deq103","volume":"25","author":"L Simon","year":"2010","unstructured":"Simon L, Brunborg G, Stevenson M et al (2010) Clinical significance of sperm DNA damage in assisted reproduction outcome. Hum Reprod 25:1594\u20131608","journal-title":"Hum Reprod"},{"key":"10_CR0010143","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1016\/j.rbmo.2011.08.010","volume":"23","author":"L Simon","year":"2011","unstructured":"Simon L, Castillo J, Oliva R et al (2011) Relationships between human sperm protamines, DNA damage and assisted reproduction outcomes. Reprod Biomed Online 23:724\u2013734","journal-title":"Reprod Biomed Online"},{"key":"10_CR0010144","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.rbmo.2012.09.019","volume":"26","author":"L Simon","year":"2013","unstructured":"Simon L, Proutski I, Stevenson M et al (2013) Sperm DNA damage has a negative association with live-birth rates after IVF. Reprod Biomed Online 26:68\u201378","journal-title":"Reprod Biomed Online"},{"key":"10_CR0010146","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1016\/j.rbmo.2010.05.017","volume":"21","author":"A Souza Setti","year":"2010","unstructured":"Souza Setti A, Ferreira RC, de Almeida P, Ferreira Braga D et al (2010) Intracytoplasmic sperm injection outcome versus intracytoplasmic morphologically selected sperm injection outcome: a meta-analysis. Reprod Biomed Online 21:450\u2013455","journal-title":"Reprod Biomed Online"},{"key":"10_CR0010145","doi-asserted-by":"crossref","first-page":"2711","DOI":"10.1016\/j.fertnstert.2011.03.003","volume":"95","author":"A Souza Setti","year":"2011","unstructured":"Souza Setti A, Figueira RD, de Almeida P, Ferreira Braga D et al (2011) Intracytoplasmic morphologically selected sperm injection benefits for patients with oligoasthenozoospermia according to the 2010 World Health Organization reference values. Fertil Steril 95:2711\u20132714","journal-title":"Fertil Steril"},{"key":"10_CR0010147","doi-asserted-by":"crossref","unstructured":"Souza Setti A, de C\u00e1ssia S\u00e1vio Figueira R, Paes de Almeida Ferreira Braga D et al (2013) IMSI is beneficial in cases of advanced maternal age: a prospective randomized study. Reprod Biomed Online. In Press","DOI":"10.1016\/j.rbmo.2012.10.020"},{"key":"10_CR0010148","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S0015-0282(99)00462-8","volume":"73","author":"M Span\u00f2","year":"2000","unstructured":"Span\u00f2 M, Bonde JP, Hj\u00f8llund HI et al (2000) Sperm chromatin damage impairs human fertility. The Danish first pregnancy planner study team. Fertil Steril 73:43\u201350","journal-title":"Fertil Steril"},{"key":"10_CR0010149","doi-asserted-by":"crossref","first-page":"1609","DOI":"10.1093\/humrep\/deq116","volume":"25","author":"BE Speyer","year":"2010","unstructured":"Speyer BE, Pizzey AR, Ranieri M et al (2010) Fall in implantation rates following ICSI with sperm with high DNA fragmentation. Hum Reprod 25:1609\u20131618","journal-title":"Hum Reprod"},{"key":"10_CR0010150","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1016\/j.fertnstert.2007.01.059","volume":"90","author":"J Stevanato","year":"2008","unstructured":"Stevanato J, Bertolla RP, Barradas V et al (2008) Semen processing by density gradient centrifugation does not improve sperm apoptotic deoxyribonucleic acid fragmentation rates. Fertil Steril 90:899\u2013890","journal-title":"Fertil Steril"},{"key":"10_CR0010151","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1095\/biolreprod56.3.602","volume":"56","author":"JG Sun","year":"1997","unstructured":"Sun JG, Jurisicova A, Casper RF (1997) Detection of deoxyribonucleic acid fragmentation in human sperm: correlation with fertilization in vitro. Biol Reprod 56:602\u2013607","journal-title":"Biol Reprod"},{"key":"10_CR0010152","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1093\/oxfordjournals.humrep.a019289","volume":"11","author":"P Svalander","year":"1996","unstructured":"Svalander P, Jakobsson AH, Forsberg AS et al (1996) The outcome of intracytoplasmic sperm injection is unrelated to \u2018strict criteria\u2019 sperm morphology. Hum Reprod 11:1019\u20131022","journal-title":"Hum Reprod"},{"issue":"Suppl 3","key":"10_CR0010153","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/S1472-6483(10)60282-9","volume":"19","author":"N Tarozzi","year":"2009","unstructured":"Tarozzi N, Nadalini M, Bizzaro D et al (2009) Sperm-hyaluronan-binding assay: clinical value in conventional IVF under Italian law. Reprod Biomed Online 19(Suppl 3):35\u201343","journal-title":"Reprod Biomed Online"},{"key":"10_CR0010185","doi-asserted-by":"crossref","first-page":"2160","DOI":"10.1093\/humrep\/16.10.2160","volume":"16","author":"MJ Tomlinson","year":"2001","unstructured":"Tomlinson MJ, Moffatt O, Manicardi GC et al (2001) Interrelationships between seminal parameters and sperm nuclear DNA damage before and after density gradient centrifugation: implications for assisted conception. Hum Reprod 16:2160\u20132165","journal-title":"Hum Reprod"},{"key":"10_CR0010154","doi-asserted-by":"crossref","first-page":"1856","DOI":"10.1093\/humrep\/17.7.1856","volume":"17","author":"M Tomsu","year":"2002","unstructured":"Tomsu M, Sharma V, Miller D (2002) Embryo quality and IVF treatment outcomes may correlate with different sperm comet assay parameters. Hum Reprod 17:1856\u20131862","journal-title":"Hum Reprod"},{"key":"10_CR0010155","doi-asserted-by":"crossref","first-page":"2109","DOI":"10.1016\/j.fertnstert.2009.05.059","volume":"92","author":"E Toro","year":"2009","unstructured":"Toro E, Fern\u00e1ndez S, Colomar A et al (2009) Processing of semen can result in increased sperm DNA fragmentation. Fertil Steril 92:2109\u20132112","journal-title":"Fertil Steril"},{"key":"10_CR0010156","doi-asserted-by":"crossref","first-page":"1864","DOI":"10.1093\/humrep\/13.7.1864","volume":"13","author":"JP Twigg","year":"1998","unstructured":"Twigg JP, Irvine DS, Aitken RJ (1998) Oxidative damage to DNA in human spermatozoa does not preclude pronucleus formation at intracytoplasmic sperm injection. Hum Reprod 13:1864\u20131871","journal-title":"Hum Reprod"},{"key":"10_CR0010157","doi-asserted-by":"crossref","first-page":"182","DOI":"10.5152\/jtgga.2010.34","volume":"11","author":"D Upadhya","year":"2010","unstructured":"Upadhya D, Kalthur G, Kumar P et al (2010) Association between the extent of DNA damage in the spermatozoa, fertilization and developmental competence in preimplantation stage embryos. J Turkish-German Gynecol Assoc 11:182\u2013186","journal-title":"J Turkish-German Gynecol Assoc"},{"key":"10_CR0010158","doi-asserted-by":"crossref","first-page":"3103","DOI":"10.1093\/humrep\/13.11.3103","volume":"13","author":"M Van den Bergh","year":"1998","unstructured":"Van den Bergh M, Emiliani S, Biramane J et al (1998) A first prospective study of the individual straight line velocity of the spermatozoon and its influences on the fertilization rate after intracytoplasmic sperm injection. Hum Reprod 13:3103\u20133107","journal-title":"Hum Reprod"},{"key":"10_CR0010159","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1016\/j.rbmo.2009.09.022","volume":"19","author":"M Van Den Bergh","year":"2009","unstructured":"Van Den Bergh M, Fahy-Deshe M, Hohl MK (2009) Pronuclear zygote score following intracytoplasmic injection of hyaluronan-bound spermatozoa: a prospective randomized study. Reprod Biomed Online 19:796\u2013801","journal-title":"Reprod Biomed Online"},{"key":"10_CR0010160","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1093\/oxfordjournals.humrep.a138192","volume":"8","author":"AC Van Steirteghem","year":"1993","unstructured":"Van Steirteghem AC, Nagy Z, Joris H et al (1993) High fertilization and implantation rates after intracytoplasmic sperm injection. Hum Reprod 8:1061\u20131066","journal-title":"Hum Reprod"},{"key":"10_CR0010161","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1093\/humupd\/8.2.111","volume":"8","author":"AC Van Steirteghem","year":"2002","unstructured":"Van Steirteghem AC, Bonduelle M, Devroey P et al (2002) Follow-up of children born after ICSI. Hum Reprod Update 8:111\u2013116","journal-title":"Hum Reprod Update"},{"key":"10_CR0010162","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1016\/S1472-6483(10)60308-2","volume":"17","author":"P Vanderzwalmen","year":"2008","unstructured":"Vanderzwalmen P, Hiemer A, Rubner P et al (2008) Blastocyst development after sperm selection at high magnification is associated with size and number of nuclear vacuoles. Reprod Biomed Online 17:617\u2013627","journal-title":"Reprod Biomed Online"},{"key":"10_CR0010163","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1111\/j.1439-0272.2009.00917.x","volume":"41","author":"AC Varghese","year":"2009","unstructured":"Varghese AC, Bragais FM, Mukhopadhyay D et al (2009) Human sperm DNA integrity in normal and abnormal semen samples and its correlation with sperm characteristics. Andrologia 41:207\u2013215","journal-title":"Andrologia"},{"key":"10_CR0010164","doi-asserted-by":"crossref","first-page":"1792","DOI":"10.1016\/j.fertnstert.2007.09.021","volume":"90","author":"JF Velez de la Calle","year":"2008","unstructured":"Velez de la Calle JF, Muller A, Walschaerts M et al (2008) Sperm deoxyribonucleic acid fragmentation as assessed by the sperm chromatin dispersion test in assisted reproductive technology programs: results of a large prospective multicenter study. Fertil Steril 90:1792\u20131799","journal-title":"Fertil Steril"},{"key":"10_CR0010165","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1023\/A:1016006509036","volume":"19","author":"I Virant-Klun","year":"2002","unstructured":"Virant-Klun I, Tomazevic T, Meden-Vrtovec H (2002) Sperm single-stranded DNA, detected by acridine orange staining, reduces fertilization and quality of ICSI-derived embryos. J Assist Reprod Genet 19:319\u2013328","journal-title":"J Assist Reprod Genet"},{"key":"10_CR0010166","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1016\/j.fertnstert.2003.09.063","volume":"81","author":"MR Virro","year":"2004","unstructured":"Virro MR, Larson-Cook KL, Evenson DP (2004) Sperm chromatin structure assay (SCSA) parameters are related to fertilization, blastocyst development, and ongoing pregnancy in in vitro fertilization and intracytoplasmic sperm injection cycles. Fertil Steril 81:1289\u20131295","journal-title":"Fertil Steril"},{"key":"10_CR0010167","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1007\/s10815-010-9505-5","volume":"28","author":"M Wilding","year":"2011","unstructured":"Wilding M, Coppola G, di Matteo L et al (2011) Intracytoplasmic injection of morphologically selected spermatozoa (IMSI) improves outcome after assisted reproduction by deselecting physiologically poor quality spermatozoa. J Assist Reprod Genet 28:253\u2013262","journal-title":"J Assist Reprod Genet"},{"key":"10_CR0010168","doi-asserted-by":"crossref","first-page":"1759","DOI":"10.1093\/humrep\/der136","volume":"7","author":"GH Woldringh","year":"2011","unstructured":"Woldringh GH, Horvers M, Janssen AJ et al (2011) Follow-up of children born after ICSI with epididymal spermatozoa. Hum Reprod 7:1759\u20131767","journal-title":"Hum Reprod"},{"issue":"1","key":"10_CR0010169","doi-asserted-by":"crossref","first-page":"s37","DOI":"10.1016\/j.fertnstert.2007.07.133","volume":"88","author":"KC Worrilow","year":"2007","unstructured":"Worrilow KC, Huynh HT, Bower JB et al (2007) PICSI vs. ICSI: statistically significant improvement in clinical outcomes in 240 in vitro fertilization (IVF) patients. Fertil Steril 88(1):s37","journal-title":"Fertil Steril"},{"issue":"1","key":"10_CR0010170","first-page":"i7","volume":"25","author":"KC Worrilow","year":"2010","unstructured":"Worrilow KC, Eid S, Matthews J et al (2010) Multi-site clinical trial evaluating PICSI, a method for selection of hyaluronan bound sperm (HBS) for use in ICSI: improved clinical outcomes. Hum Reprod 25(1):i7","journal-title":"Hum Reprod"},{"key":"10_CR0010171","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1093\/humrep\/des417","volume":"28","author":"KC Worrilow","year":"2013","unstructured":"Worrilow KC, Eid S, Woodhouse D et al (2013) Use of hyaluronan in the selection of sperm for intracytoplasmic sperm injection (ICSI): significant improvement in clinical outcomes\u2013multicenter, double-blinded and randomized controlled trial. Hum Reprod 28:306\u2013314","journal-title":"Hum Reprod"},{"key":"10_CR0010172","doi-asserted-by":"crossref","first-page":"566","DOI":"10.2164\/jandrol.109.008912","volume":"31","author":"A Yagci","year":"2010","unstructured":"Yagci A, Murk W, Stronk J et al (2010) Spermatozoa bound to solid state hyaluronic acid show chromatin structure with high DNA chain integrity: an acridine orange fluorescence study. J Androl 31:566\u2013572","journal-title":"J Androl"},{"key":"10_CR0010173","first-page":"189","volume-title":"The physiology of reproduction","author":"R Yanagimachi","year":"1994","unstructured":"Yanagimachi R (1994) Mammalian fertilization. In: Knobil E, Neill JD (eds) The physiology of reproduction. Raven Press Ltd, New York, pp 189\u2013317"},{"key":"10_CR0010174","doi-asserted-by":"crossref","first-page":"1545","DOI":"10.1093\/humrep\/del008","volume":"21","author":"H Ye","year":"2006","unstructured":"Ye H, Huang GN, Gao Y, de Liu Y (2006) Relationship between human sperm-hyaluronan binding assay and fertilization rate in conventional in vitro fertilization. Hum Reprod 21:1545\u20131550","journal-title":"Hum Reprod"},{"key":"10_CR0010175","doi-asserted-by":"crossref","first-page":"1950","DOI":"10.1093\/humrep\/16.9.1950","volume":"16","author":"EV Younglai","year":"2001","unstructured":"Younglai EV, Holt D, Brown P et al (2001) Sperm swim-up techniques and DNA fragmentation. Hum Reprod 16:1950\u20131953","journal-title":"Hum Reprod"},{"key":"10_CR0010176","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1016\/j.fertnstert.2009.04.034","volume":"94","author":"LH Zhang","year":"2010","unstructured":"Zhang LH, Qiu Y, Wang KH et al (2010) Measurement of sperm DNA fragmentation using bright-field microscopy: comparison between sperm chromatin dispersion test and terminal uridine nick-end labeling assay. Fertil Steril 94:1027\u20131032","journal-title":"Fertil Steril"},{"key":"10_CR0010179","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1016\/S0090-4295(00)00770-6","volume":"56","author":"A Zini","year":"2000","unstructured":"Zini A, Finelli A, Phang D et al (2000a) Influence of semen processing technique on human sperm DNA integrity. Urology 56:1081\u20131084","journal-title":"Urology"},{"key":"10_CR0010180","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1016\/S0015-0282(00)01495-3","volume":"74","author":"A Zini","year":"2000","unstructured":"Zini A, Nam RK, Mak V et al (2000b) Influence of initial semen quality on the integrity of human sperm DNA following semen processing. Fertil Steril 74:824\u2013827","journal-title":"Fertil Steril"},{"key":"10_CR0010181","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1016\/S0015-0282(00)01796-9","volume":"75","author":"A Zini","year":"2001","unstructured":"Zini A, Bielecki R, Phang D et al (2001) Correlations between two markers of sperm DNA integrity, DNA denaturation and DNA fragmentation, in fertile and infertile men. Fertil Steril 75:674\u2013677","journal-title":"Fertil Steril"},{"key":"10_CR0010182","doi-asserted-by":"crossref","first-page":"2663","DOI":"10.1093\/humrep\/den321","volume":"23","author":"A Zini","year":"2008","unstructured":"Zini A, Boman JM, Belzile E et al (2008) Sperm DNA damage is associated with an increased risk of pregnancy loss after IVF and ICSI: systematic review and meta-analysis. Hum Reprod 23:2663\u20132668","journal-title":"Hum Reprod"}],"container-title":["Advances in Experimental Medicine and Biology","Genetic Damage in Human Spermatozoa"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/978-1-4614-7783-9_10","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,16]],"date-time":"2024-05-16T16:51:12Z","timestamp":1715878272000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/978-1-4614-7783-9_10"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,7,11]]},"ISBN":["9781461477822","9781461477839"],"references-count":182,"URL":"https:\/\/doi.org\/10.1007\/978-1-4614-7783-9_10","relation":{},"ISSN":["0065-2598","2214-8019"],"issn-type":[{"value":"0065-2598","type":"print"},{"value":"2214-8019","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,7,11]]},"assertion":[{"value":"11 July 2013","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}}]}}