{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T20:58:53Z","timestamp":1773867533892,"version":"3.50.1"},"publisher-location":"Boston, MA","reference-count":7,"publisher":"Springer US","isbn-type":[{"value":"9781461352082","type":"print"},{"value":"9781461507178","type":"electronic"}],"license":[{"start":{"date-parts":[[2002,1,1]],"date-time":"2002-01-01T00:00:00Z","timestamp":1009843200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2002]]},"DOI":"10.1007\/978-1-4615-0717-8_114","type":"book-chapter","created":{"date-parts":[[2017,7,6]],"date-time":"2017-07-06T14:46:37Z","timestamp":1499352397000},"page":"805-812","source":"Crossref","is-referenced-by-count":4,"title":["Topical Cyclosporine a (2%) Eyedrops in the Therapy of Atopic Keratoconjunctivitis and Keratoconjunctivitis Vernalis"],"prefix":"10.1007","author":[{"given":"I.","family":"Tomida","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Br\u00e4uning","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Schlote","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. E.","family":"Heide","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Zierhut","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"114_CR1","doi-asserted-by":"publisher","first-page":"184","DOI":"10.1097\/00003226-199007000-00002","volume":"9","author":"MW Belin","year":"1990","unstructured":"M.W. Belin, C.S. Bouchard, and T.M. Phillips. Update on topical cyclosporine A. Cornea 9:184\u2013195 (1990).","journal-title":"Cornea"},{"key":"114_CR2","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1038\/eye.1996.95","volume":"10","author":"HS Dua","year":"1996","unstructured":"H.S. Dua, V.K. Jindal, J.A.P. Gomes, W.A. Amoaku, L.A. Donoso, P.R. Laibson, and K. Mahlberg. The effect of topical cyclosporine on conjunctiva-associated lymphoid tissue (CALT). Eye 10:433\u2013438 (1996).","journal-title":"Eye"},{"key":"114_CR3","first-page":"392","volume":"40","author":"M Hingorani","year":"1999","unstructured":"M. Hingorani, V.L. Calder, R.J. Buckley, and S. Lightman. The immunomodulatory effect of topical cyclosporine A in atopic keratoconjunctivitis. Invest Ophthalmol Vis Sci 40:392\u2013399 (1999).","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"114_CR4","first-page":"2686","volume":"37","author":"SM Whitcup","year":"1996","unstructured":"S.M. Whitcup, C.-C. Chan, D.A. Luyo, P. Bo, and Q. Li. Topical cyclosporine inhibits mast cell-mediated conjunctivitis. Invest Ophthalmol Vis Sci 37:2686\u20132693 (1996).","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"114_CR5","doi-asserted-by":"publisher","first-page":"631","DOI":"10.1016\/S0161-6420(99)00176-1","volume":"107","author":"K Sall","year":"2000","unstructured":"K. Sall, O.D. Stevenson, T.K. Mundorf, B.L. Reis. Two multicenter, randomized studies of the efficacy and safety of cyclosporine ophthalmic emulsion in moderate to severe dry eye disease. Ophthalmology 107:631\u2013639 (2000).","journal-title":"Ophthalmology"},{"key":"114_CR6","doi-asserted-by":"publisher","first-page":"641","DOI":"10.1016\/S0002-9394(14)77061-8","volume":"110","author":"AG Secchi","year":"1990","unstructured":"A.G. Secchi, M.S. Tognon, and A. Leonardi. Topical use of cyclosporine in the treatment of vernal keratoconjunctivitis. Am J Ophthalmol 110:641\u2013645 (1990).","journal-title":"Am J Ophthalmol"},{"key":"114_CR7","doi-asserted-by":"publisher","first-page":"1715","DOI":"10.1016\/S0161-6420(98)99043-1","volume":"105","author":"M Hingorani","year":"1998","unstructured":"M. Hingorani, L. Moodaley, V.L. Calder, R.J. Buckley, S. Lightman. A randomized, placebo-controlled trial of topical cyclosporine A in steroid-dependent atopic keratoconjunctivitis. Ophthalmology 105:1715\u20131720 (1998).","journal-title":"Ophthalmology"}],"container-title":["Advances in Experimental Medicine and Biology","Lacrimal Gland, Tear Film, and Dry Eye Syndromes 3"],"original-title":[],"link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/978-1-4615-0717-8_114","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,7,6]],"date-time":"2017-07-06T14:57:01Z","timestamp":1499353021000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/978-1-4615-0717-8_114"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002]]},"ISBN":["9781461352082","9781461507178"],"references-count":7,"URL":"https:\/\/doi.org\/10.1007\/978-1-4615-0717-8_114","relation":{},"ISSN":["0065-2598","2214-8019"],"issn-type":[{"value":"0065-2598","type":"print"},{"value":"2214-8019","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002]]}}}