{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T04:16:58Z","timestamp":1781237818448,"version":"3.54.1"},"publisher-location":"Boston, MA","reference-count":20,"publisher":"Springer US","isbn-type":[{"value":"9781461365150","type":"print"},{"value":"9781461534266","type":"electronic"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1992]]},"DOI":"10.1007\/978-1-4615-3426-6_30","type":"book-chapter","created":{"date-parts":[[2011,10,19]],"date-time":"2011-10-19T18:05:35Z","timestamp":1319047535000},"page":"331-340","source":"Crossref","is-referenced-by-count":23,"title":["Very Long-Chain Fatty Acids in Peroxisomal Disease"],"prefix":"10.1007","author":[{"given":"A.","family":"Poulos","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Beckman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. W.","family":"Johnson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B. C.","family":"Paton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B. S.","family":"Robinson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Sharp","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Usher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"30_CR1","doi-asserted-by":"crossref","first-page":"1180","DOI":"10.1016\/S0021-9258(19)75768-8","volume":"262","author":"M Avelda\u00f1o","year":"1987","unstructured":"Avelda\u00f1o M and Sprecher H (1987) Very long-chain (C24-C36) polyenoic fatty acids of the n-3 and n-6 series in dipolyunsaturated phosphatidylcholines from bovine retina. J Biol Chem 262: 1180\u20131186.","journal-title":"J Biol Chem"},{"key":"30_CR2","doi-asserted-by":"publisher","first-page":"911","DOI":"10.1139\/o59-099","volume":"37","author":"BG Bligh","year":"1959","unstructured":"Bligh BG and Dyer WJ (1959) A rapid method of total lipid extraction and purification, Can J Biochem Physiol 37: 911\u2013917.","journal-title":"Can J Biochem Physiol"},{"key":"30_CR3","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1016\/0009-3084(90)90089-A","volume":"56","author":"DW Johnson","year":"1990","unstructured":"Johnson DW (1990) A synthesis of unsaturated very long-chain fatty acids. Chem Phys Lipids 56: 65\u201371.","journal-title":"Chem Phys Lipids"},{"key":"30_CR4","doi-asserted-by":"crossref","unstructured":"Johnson DW, Beckman K, Robinson BS, Fellenberg AF, Poulos A (in press). Monoenoic fatty acids in human brain: Isomer identification and distribution. Lipids.","DOI":"10.1007\/BF02536174"},{"key":"30_CR5","doi-asserted-by":"publisher","first-page":"722","DOI":"10.1016\/0003-9861(89)90555-9","volume":"270","author":"O Lazo","year":"1989","unstructured":"Lazo O, Contreras M, Bhushan A, Stanley W, Singh I (1989) Adrenoleukodystrophy: Impaired oxidation of fatty acids due to peroxisomal lignoceroyl-CoA ligase deficiency. Arch Biochem Biophys 270: 722\u2013728.","journal-title":"Arch Biochem Biophys"},{"key":"30_CR6","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1016\/0020-711X(81)90132-4","volume":"13","author":"JM Naughton","year":"1981","unstructured":"Naughton JM (1981) Supply of polyenoic fatty acids to the mammalian brain: The ease of conversion of the short chain fatty acids to their longer chain polyunsaturated metabolites in liver, brain, placenta and blood. Int J Biochem 13: 21\u201332.","journal-title":"Int J Biochem"},{"key":"30_CR7","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1212\/WNL.39.1.44","volume":"39","author":"A Poulos","year":"1989","unstructured":"Poulos A, Sharp P, Johnson DW (1989) Polyenoic very long-chain fatty acids in peroxisomal disease. Biochemical discrimination of Zellweger\u2019s syndrome from other phenotypes. Neurology 39: 44\u201347.","journal-title":"Neurology"},{"key":"30_CR8","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1042\/bj2530645","volume":"253","author":"A Poulos","year":"1988","unstructured":"Poulos A, Sharp P, Johnson DW, Easton C (1988) The occurrence of polyenoic very long chain fatty acids with greater than 32 carbon atoms in molecular species of phosphatidylcholine in normal and peroxisome-deficient (Zellweger\u2019s syndrome) brain. Biochem J 253: 645\u2013650.","journal-title":"Biochem J"},{"key":"30_CR9","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1042\/bj2400891","volume":"240","author":"A Poulos","year":"1986","unstructured":"Poulos A, Sharp P, Johnson D, White IG, Fellenberg A (1986a) The occurrence of polyenoic fatty acids with greater than 22 carbon atoms in mammalian spermatozoa. Biochem J 240: 891\u2013895.","journal-title":"Biochem J"},{"key":"30_CR10","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1042\/bj2350607","volume":"235","author":"A Poulos","year":"1986","unstructured":"Poulos A, Sharp P, Singh H, Johnson D, Fellenberg AJ, Pollard AC (1986b) Detection of a homologous series of C26-C38 polyenoic fatty acids in the brains of patients without peroxisomes (Zellweger\u2019s syndrome). Biochem J 235: 607\u2013610.","journal-title":"Biochem J"},{"key":"30_CR11","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1111\/j.1399-0004.1986.tb00511.x","volume":"29","author":"A Poulos","year":"1986","unstructured":"Poulos A, Singh H, Paton B, Sharp P, Derwas N (1986c) Accumulation and defective \u00df-oxidation of very long-chain fatty acids in Zellweger\u2019s syndrome, adrenoleukodystrophy, and Refsum\u2019s disease variants. Clin Genet 29: 397\u2013408.","journal-title":"Clin Genet"},{"key":"30_CR12","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1042\/bj2670561","volume":"267","author":"BS Robinson","year":"1990","unstructured":"Robinson BS, Johnson DW, Poulos A (1990a) Metabolism of hexacosatetraenoic acid (C26:4, n-6) in immature rat brain. Biochem J 267: 561\u2013564.","journal-title":"Biochem J"},{"key":"30_CR13","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1042\/bj2650763","volume":"265","author":"BS Robinson","year":"1990","unstructured":"Robinson BS, Johnson DW, Poulos A (1990b) Unique molecular species of phosphatidylcholine containing very-long-chain (C24-C38) polyenoic fatty acids in rat brain. Biochem J 265: 763\u2013767.","journal-title":"Biochem J"},{"key":"30_CR14","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1111\/j.1471-4159.1991.tb02558.x","volume":"56","author":"P Sharp","year":"1991","unstructured":"Sharp P, Johnson DW, Poulos A (1991) Molecular species of phosphatidylcholine containing very long chain fatty acids in human brain: Enrichment in X-linked adrenoleukodystrophy brain and diseases of peroxisomal biogenesis brain. J Neurochem 56: 30\u201337.","journal-title":"J Neurochem"},{"key":"30_CR15","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1042\/bj2480061","volume":"248","author":"P Sharp","year":"1987","unstructured":"Sharp P, Pernios A, Fellenberg AJ, Johnson D (1987) Structure and distribution of polyenoic very long-chain fatty acids in the brain of peroxisome-deficient patients (Zellweger syndrome). Biochem J 248: 61\u201367.","journal-title":"Biochem J"},{"key":"30_CR16","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/S0022-2275(20)43207-9","volume":"31","author":"H Singh","year":"1990","unstructured":"Singh H, Usher S, Johnson DW, Poulos A (1990) A comparative study of straight chain and branched chain fatty acid oxidation in skin fibroblasts from patients with peroxisomal disorders. J Lipid Res 31: 217\u2013225.","journal-title":"J Lipid Res"},{"key":"30_CR17","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1042\/bj2600647","volume":"260","author":"JM Street","year":"1989","unstructured":"Street JM, Johnson DW, Singh H, Poulos A (1989) Metabolism of saturated and polyunsaturated fatty acids by normal and Zellweger syndrome skin fibroblasts. Biochem J 260: 647\u2013655.","journal-title":"Biochem J"},{"key":"30_CR18","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/0022-510X(88)90203-1","volume":"88","author":"RJA Wanders","year":"1988","unstructured":"Wanders RJA, Heymans HSA, Schutgens RB, Barth PG, van den Bosch H, Tager JM (1988a) Peroxisomal disorders in neurology. J Neurol Sci 88: 1\u201339.","journal-title":"J Neurol Sci"},{"key":"30_CR19","doi-asserted-by":"publisher","first-page":"1778","DOI":"10.1172\/JCI113271","volume":"80","author":"RJA Wanders","year":"1987","unstructured":"Wanders RJA, van Roermund CWT, van Wijland MJA, Schutgens RBH, Heikoop J, van den Bosch H, Schram AW, Tager JM (1987) Peroxisomal fatty acid \u00df-oxidation in relation to the accumulation of very long-chain fatty acids in cultured skin fibroblasts from patients with Zellweger syndrome and other peroxisomal disorders. J Clin Invest 80: 1778\u20131783.","journal-title":"J Clin Invest"},{"key":"30_CR20","doi-asserted-by":"publisher","first-page":"618","DOI":"10.1016\/S0006-291X(88)81140-9","volume":"153","author":"RJA Wanders","year":"1988","unstructured":"Wanders RJA, van Roermund CWT, van Wijland MJA, Schutgens RBH, van den Bosch H, Schram AW, Tager JM (1988b) Direct demonstration that the deficient oxidation of very long-chain fatty acids in X-linked adrenoleukodystrophy is due to an impaired ability of peroxisomes to activate very long-chain fatty acids. Biochem Biophys Res Commun 153: 618\u2013624.","journal-title":"Biochem Biophys Res Commun"}],"container-title":["Advances in Experimental Medicine and Biology","Neurobiology of Essential Fatty Acids"],"original-title":[],"link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/978-1-4615-3426-6_30","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,11]],"date-time":"2021-12-11T17:24:35Z","timestamp":1639243475000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/978-1-4615-3426-6_30"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1992]]},"ISBN":["9781461365150","9781461534266"],"references-count":20,"URL":"https:\/\/doi.org\/10.1007\/978-1-4615-3426-6_30","relation":{},"ISSN":["0065-2598"],"issn-type":[{"value":"0065-2598","type":"print"}],"subject":[],"published":{"date-parts":[[1992]]}}}