{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T11:25:38Z","timestamp":1789730738366,"version":"4.0.1"},"publisher-location":"Boston, MA","reference-count":36,"publisher":"Springer US","isbn-type":[{"value":"9781461377023","type":"print"},{"value":"9781461558910","type":"electronic"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1996]]},"DOI":"10.1007\/978-1-4615-5891-0_44","type":"book-chapter","created":{"date-parts":[[2011,9,16]],"date-time":"2011-09-16T14:02:43Z","timestamp":1316181763000},"page":"291-297","source":"Crossref","is-referenced-by-count":6,"title":["Domperidone as a Tool to Assess the Role of Dopamine within Carotid Body Chemoreception"],"prefix":"10.1007","author":[{"given":"P.","family":"Zapata","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Iturriaga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Larra\u00edn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"44_CR1","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1016\/0034-5687(79)90092-6","volume":"37","author":"GE Bisgard","year":"1979","unstructured":"Bisgard GE, Mitchell RA & Herbert DA (1979) Effects of dopamine, norepinephrine, and 5-hydroxytryptamine on the carotid body of the dog. Respir Physiol 37: 61\u201380","journal-title":"Respir Physiol"},{"key":"44_CR2","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1016\/0165-1838(92)90124-Y","volume":"41","author":"MF Czyzyk-Krzeska","year":"1992","unstructured":"Czyzyk-Krzeska MF, Lawson EE & Millhorn DE (1992) Expression of D2 dopamine receptor mRNA in the arterial chemoreceptor afferent pathway. J Auton Nerv Syst 41: 31\u201339","journal-title":"J Auton Nerv Syst"},{"key":"44_CR3","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1016\/0304-3940(81)90056-2","volume":"21","author":"B Dinger","year":"1981","unstructured":"Dinger B, Gonzalez C, Yoshizaki K & Fidone S (1981) [3H] Spiroperidol binding in normal and denervated carotid bodies. Neurosci Lett 21: 51\u201355","journal-title":"Neurosci Lett"},{"key":"44_CR4","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1113\/jphysiol.1978.sp012354","volume":"279","author":"RJ Docherty","year":"1978","unstructured":"Docherty RJ & McQueen DS (1978) Inhibitory action of dopamine on cat carotid chemoreceptors. J Physiol, London 279: 425\u2013436","journal-title":"J Physiol, London"},{"key":"44_CR5","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1113\/jphysiol.1979.sp012704","volume":"288","author":"RJ Docherty","year":"1979","unstructured":"Docherty RJ & McQueen DS (1979) The effects of acetylcholine and dopamine on carotid chemosensory activity in the rabbit. J Physiol, London 288: 411\u2013423","journal-title":"J Physiol, London"},{"key":"44_CR6","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1152\/jappl.1984.57.4.931","volume":"57","author":"C Eyzaguirre","year":"1984","unstructured":"Eyzaguirre C & Zapata P (1984) Perspectives in carotid body research. J Appl Physiol 57: 931\u2013957","journal-title":"J Appl Physiol"},{"key":"44_CR7","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1113\/jphysiol.1982.sp014441","volume":"333","author":"S Fidone","year":"1982","unstructured":"Fidone S, Gonzalez C & Yoshizaki K (1982) Effects of low oxygen on the release of dopamine from the rabbit carotid body in vitro. J Physiol, London 333: 93\u2013110","journal-title":"J Physiol, London"},{"key":"44_CR8","first-page":"21","volume-title":"Physiology of the Peripheral Arterial Chemoreceptors","author":"SJ Fidone","year":"1983","unstructured":"Fidone SJ, Stensaas LJ & Zapata P (1983) Sites of synthesis, storage, release and recognition of biogenic amines in carotid bodies. In: Acker H & O\u2019Regan RG (eds) Physiology of the Peripheral Arterial Chemoreceptors. Amsterdam: Elsevier. pp 21\u201344"},{"key":"44_CR9","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1113\/jphysiol.1982.sp014131","volume":"325","author":"H Folgering","year":"1982","unstructured":"Folgering H, Ponte J & Sadig T (1982) Adrenergic mechanisms and chemoreception in the carotid body of the cat and the rabbit. J Physiol, London 325: 1\u201321","journal-title":"J Physiol, London"},{"key":"44_CR10","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1007\/978-1-4615-2572-1_56","volume":"360","author":"EB Gauda","year":"1994","unstructured":"Gauda EB, Shirahata M & Fitzgerald RS (1994) D2-dopamine receptor mRNA in the carotid body and petrosal ganglia in the developing cat. Adv Exp Med Biol 360: 317\u2013319","journal-title":"Adv Exp Med Biol"},{"key":"44_CR11","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1016\/0006-8993(84)90189-6","volume":"321","author":"WF Goldman","year":"1984","unstructured":"Goldman WF & Eyzaguirre C (1984) The effect of dopamine on glomus cell membranes in the rabbit. Brain Res 321:337\u2013340","journal-title":"Brain Res"},{"key":"44_CR12","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1152\/physrev.1994.74.4.829","volume":"74","author":"C Gonzalez","year":"1994","unstructured":"Gonzalez C, Almaraz L, Obeso A & Rigual R (1994) Carotid body chemoreceptors: from natural stimuli to sensory discharges. Physiol Rev 74: 829\u2013898","journal-title":"Physiol Rev"},{"key":"44_CR13","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1113\/jphysiol.1978.sp012445","volume":"282","author":"I Hanbauer","year":"1978","unstructured":"Hanbauer I & Hellstr\u00f6m S (1978) The regulation of dopamine and noradrenaline in the rat carotid body and its modification by denervation and by hypoxia. J Physiol, London 282: 21\u201334","journal-title":"J Physiol, London"},{"key":"44_CR14","doi-asserted-by":"publisher","first-page":"352","DOI":"10.1016\/0006-8993(76)90725-3","volume":"118","author":"S Hellstr\u00f6m","year":"1976","unstructured":"Hellstr\u00f6m S, Hanbauer I & Costa E (1976) Selective decrease of dopamine content in rat carotid body during exposure to hypoxic conditions. Brain Res 118: 352\u2013355","journal-title":"Brain Res"},{"key":"44_CR15","first-page":"51","volume-title":"The Peripheral Arterial Chemoreceptors","author":"A Hess","year":"1975","unstructured":"Hess A (1975) The significance of the ultrastructure of the rat carotid body in structure and function of chemoreceptors. In: Purves MJ (ed) The Peripheral Arterial Chemoreceptors. London: Cambridge Univ Press. pp 51\u201373"},{"key":"44_CR16","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1016\/0034-5687(89)90073-X","volume":"76","author":"C Hsiao","year":"1989","unstructured":"Hsiao C, Lahiri S & Mokashi A (1989) Peripheral and central dopamine receptors in respiratory control. Respir Physiol 76: 327\u2013336","journal-title":"Respir Physiol"},{"key":"44_CR17","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1016\/0006-8993(94)90472-3","volume":"663","author":"R Iturriaga","year":"1994","unstructured":"Iturriaga R, Larrain C & Zapata P (1994) Effects of dopaminergic blockade upon carotid chemosensory activity and its hypoxia-induced excitation. Brain Res 663: 145\u2013154","journal-title":"Brain Res"},{"key":"44_CR18","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1016\/0034-5687(86)90048-4","volume":"65","author":"NA Kressin","year":"1986","unstructured":"Kressin NA, Nielsen AM, Laravuso R & Bisgard GE (1986) Domperidone-induced potentiation of ventilatory responses in awake goats. Respir Physiol 65: 169\u2013180","journal-title":"Respir Physiol"},{"key":"44_CR19","doi-asserted-by":"publisher","first-page":"2161","DOI":"10.1016\/0006-2952(79)90198-9","volume":"28","author":"PM Laduron","year":"1979","unstructured":"Laduron PM & Leysen JE (1979) Domperidone, a specific in vitro dopamine antagonist, devoid of in vivo central dopaminergic activity. Biochem Pharmacol 28: 2161\u20132165","journal-title":"Biochem Pharmacol"},{"key":"44_CR20","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1016\/0304-3940(80)90166-4","volume":"20","author":"S Lahiri","year":"1980","unstructured":"Lahiri S & Nishino T (1980) Inhibitory and excitatory effects of dopamine on carotid chemoreceptors. Neurosci Lett 20: 313\u2013318","journal-title":"Neurosci Lett"},{"key":"44_CR21","doi-asserted-by":"publisher","first-page":"1901","DOI":"10.1063\/1.335995","volume":"58","author":"S Lahiri","year":"1985","unstructured":"Lahiri S, Hsiao C, Zhang R, Mokashi A & Nishino T (1985) Peripheral chemoreceptors in respiratory oscillations. J Appl Physiol 58: 1901\u20131908","journal-title":"J Appl Physiol"},{"key":"44_CR22","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1007\/978-1-4615-2966-8_26","volume":"337","author":"L-M Leitner","year":"1993","unstructured":"Leitner L-M (1993) Dopamine metabolism in the rabbit carotid body in vitro: effect of hypoxia and hypercapnia. Adv Exp Med Biol 337: 183\u2013190","journal-title":"Adv Exp Med Biol"},{"key":"44_CR23","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1113\/jphysiol.1978.sp012162","volume":"274","author":"F Llados","year":"1978","unstructured":"Llados F & Zapata P (1978) Effects of dopamine analogues and antagonists on carotid body chemosensors in situ. J Physiol, London 274: 487\u2013499","journal-title":"J Physiol, London"},{"key":"44_CR24","doi-asserted-by":"publisher","first-page":"674","DOI":"10.1016\/0006-8993(82)90549-2","volume":"239","author":"S Matsumoto","year":"1982","unstructured":"Matsumoto S, Nakajima T, Uchida T, Ozawa H & Uchiyama J (1982) Effects of sodium cyanide, dopamine and acetylcholine on the resting membrane potential of glomus cells in the rabbit. Brain Res 239: 674\u2013678","journal-title":"Brain Res"},{"key":"44_CR25","first-page":"325","volume-title":"The Peripheral Arterial Chemoreceptors","author":"DS McQueen","year":"1984","unstructured":"McQueen DS (1984) Effects of selective dopamine receptor agonists and antagonists on carotid body chemorecep-tor activity. In: Pallot DJ (ed) The Peripheral Arterial Chemoreceptors. London: Croom Helm. pp 325\u2013333"},{"key":"44_CR26","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1016\/0006-8993(84)91259-9","volume":"291","author":"AK Mir","year":"1984","unstructured":"Mir AK, McQueen DS, Pallot DJ & Nahorski SR (1984) Direct biochemical and neuropharmacological identification of dopamine D2-receptors in the rabbit carotid body. Brain Res 291: 273\u2013283","journal-title":"Brain Res"},{"key":"44_CR27","doi-asserted-by":"publisher","first-page":"449","DOI":"10.1016\/0006-8993(80)90177-8","volume":"193","author":"L Monti-Bloch","year":"1980","unstructured":"Monti-Bloch L & Eyzaguirre C (1980) A comparative physiological and pharmacological study of cat and rabbit carotid body chemoreceptors. Brain Res 193: 449\u2013470","journal-title":"Brain Res"},{"key":"44_CR28","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1007\/978-3-642-66755-8_21","volume-title":"Chemoreception in the Carotid Body","author":"K Nishi","year":"1977","unstructured":"Nishi K (1977) A pharmacologic study on a possible inhibitory role of dopamine in the cat carotid body chemore-ceptor. In: Acker H, Fidone S, Pallot D, Eyzaguirre C, L\u00fcbbers DW, Torrance RW (eds) Chemoreception in the Carotid Body. Berlin: Springer-Verlag. pp 145\u2013151"},{"key":"44_CR29","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1016\/0006-8993(86)90398-7","volume":"374","author":"R Rigual","year":"1986","unstructured":"Rigual R, Gonzalez E, Gonzalez C & Fidone S (1986) Synthesis and release of catecholamines by the cat carotid body in vitro: effects of hypoxic stimulation. Brain Res 374: 101\u2013109","journal-title":"Brain Res"},{"key":"44_CR30","doi-asserted-by":"publisher","first-page":"436","DOI":"10.1007\/BF00587724","volume":"411","author":"M Roumy","year":"1988","unstructured":"Roumy M, Armengaud C, Ruckebusch M, Sutra JF & Leitner L-M (1988) Fate of the catecholamine stores in the rabbit carotid body superfused in vitro. Pfl\u00fcgers Arch \u2014 Eur J Physiol 411: 436\u2013441","journal-title":"Pfl\u00fcgers Arch \u2014 Eur J Physiol"},{"key":"44_CR31","doi-asserted-by":"crossref","first-page":"1494","DOI":"10.1152\/ajplegacy.1976.230.6.1494","volume":"230","author":"SR Sampson","year":"1976","unstructured":"Sampson SR, Aminoff MJ, Jaffe RA & Vidruk EH (1976) Analysis of inhibitory effect of dopamine on carotid body chemoreceptors in cats. Am J Physiol 230: 1494\u20131498","journal-title":"Am J Physiol"},{"key":"44_CR32","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1007\/978-1-4615-2966-8_13","volume":"337","author":"A Schamel","year":"1993","unstructured":"Schamel A & Verna A (1993) Localization of dopamine D2 receptor mRNA in the rabbit carotid body and petrosal ganglion by in situ hybridization. Adv Exp Med Biol 337: 85\u201391","journal-title":"Adv Exp Med Biol"},{"key":"44_CR33","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1113\/jphysiol.1975.sp010794","volume":"244","author":"P Zapata","year":"1975","unstructured":"Zapata P (1975) Effects of dopamine on carotid chemo-and baroreceptors in vitro. J Physiol, London 244: 235\u2013251","journal-title":"J Physiol, London"},{"key":"44_CR34","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1016\/0304-3940(84)90403-8","volume":"51","author":"P Zapata","year":"1984","unstructured":"Zapata P & Torrealba F (1984) Blockade of dopamine-induced chemosensory inhibition by domperidone. Neurosci Lett 51: 359\u2013364","journal-title":"Neurosci Lett"},{"key":"44_CR35","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1016\/0304-3940(83)90403-2","volume":"42","author":"P Zapata","year":"1983","unstructured":"Zapata P, Serani A & Lavados M (1983) Inhibition in carotid body chemoreceptors mediated by D-2 dopamino-ceptors: antagonism by benzamides. Neurosci Lett 42: 179\u2013184","journal-title":"Neurosci Lett"},{"key":"44_CR36","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1007\/978-1-4615-5891-0_39","volume":"410","author":"P Zapata","year":"1996","unstructured":"Zapata P, Iturriaga R & Alcayaga J (1996) Dopamine efflux from the carotid body during hypoxic stimulation. Adv Exp Med Biol 410: 261\u2013266","journal-title":"Adv Exp Med Biol"}],"container-title":["Advances in Experimental Medicine and Biology","Frontiers in Arterial Chemoreception"],"original-title":[],"link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/978-1-4615-5891-0_44.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,11]],"date-time":"2024-04-11T20:31:59Z","timestamp":1712867519000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/978-1-4615-5891-0_44"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1996]]},"ISBN":["9781461377023","9781461558910"],"references-count":36,"URL":"https:\/\/doi.org\/10.1007\/978-1-4615-5891-0_44","relation":{},"ISSN":["0065-2598"],"issn-type":[{"value":"0065-2598","type":"print"}],"subject":[],"published":{"date-parts":[[1996]]}}}