{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T09:40:02Z","timestamp":1746092402432,"version":"3.40.4"},"publisher-location":"Boston, MA","reference-count":25,"publisher":"Springer US","isbn-type":[{"type":"print","value":"9781468436341"},{"type":"electronic","value":"9781468436327"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1980]]},"DOI":"10.1007\/978-1-4684-3632-7_17","type":"book-chapter","created":{"date-parts":[[2013,12,26]],"date-time":"2013-12-26T15:04:28Z","timestamp":1388070268000},"page":"181-195","source":"Crossref","is-referenced-by-count":3,"title":["Role of Serotonin (5-Ht) in Tolerance to Ethanol and Barbiturates"],"prefix":"10.1007","author":[{"given":"J. M.","family":"Khanna","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. D.","family":"Le","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Kalant","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. E.","family":"LeBlanc","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"17_CR1","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1016\/S0021-9258(18)70758-8","volume":"227","author":"JJ Burns","year":"1957","unstructured":"Burns, J.J., Evans, C., Trousof, N. Stimulatory effect of barbital on urinary excretion of L-ascorbic acid and non-conjugated D-glucuronic acid. J. Biol. Chem. 227;785\u2013794, 1957.","journal-title":"J. Biol. Chem."},{"key":"17_CR2","doi-asserted-by":"publisher","first-page":"657","DOI":"10.1016\/0091-3057(73)90029-4","volume":"1","author":"PL Carlton","year":"1973","unstructured":"Carlton, P.L., Advocat, C. Attenuated habituation due to parachlorophenylalanine. Pharmacol. Biochem. Behav. 1:657\u2013663, 1973.","journal-title":"Pharmacol. Biochem. Behav"},{"key":"17_CR3","doi-asserted-by":"publisher","first-page":"1215","DOI":"10.1016\/0031-9384(70)90029-6","volume":"5","author":"RL Conner","year":"1970","unstructured":"Conner, R.L., Stolk, J.M., Barchas, J.D., Levine, S. Parachlorophenylalanine and habituation to repetitive auditory startle stimuli in rats. Physiol. Behav. 5, 1215\u20131219, 1970.","journal-title":"Physiol. Behav"},{"key":"17_CR4","doi-asserted-by":"publisher","first-page":"1267","DOI":"10.1016\/0006-2952(64)90227-8","volume":"13","author":"AG Ebert","year":"1964","unstructured":"Ebert, A.G., Yim, G.K.W., Miya, T.S. Distribution and metabolism of barbital- 14C in tolerant and non-tolerant rats. Biochem. Pharmacol. 13, 1267\u20131274, 1964.","journal-title":"Biochem. Pharmacol"},{"key":"17_CR5","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1007\/BF00431839","volume":"56","author":"D Frankel","year":"1978","unstructured":"Frankel, D., Khanna, J.M., Kalant, H., Le Blanc, A.E. Effect of p-chlorophenylalanine on the loss and maintenance of tolerance to ethanol. Psychopharmacology 56:139\u2013143, 1978a.","journal-title":"Psychopharmacology"},{"key":"17_CR6","first-page":"595","volume-title":"Alcohol and Aldehyde Metabolizing Systems","author":"D Frankel","year":"1978","unstructured":"Frankel, D., Khanna, J.M., Kalant, H., Le Blanc, A.E. Effect of p-chlorophenylalanine on the acquisition maintenance and loss of tolerance to ethanol. In Alcohol and Aldehyde Metabolizing Systems (R. G. Thurman, J.R. Williamson, H. Drott and B. Chance, eds.), pp. 595\u2013603. Academic Press, New York (1978b)."},{"key":"17_CR7","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1007\/BF00426744","volume":"57","author":"D Frankel","year":"1978","unstructured":"Frankel, D., Khanna, J.M., Kalant, H., LeBlanc, A.E. Effect of p-chlorophenylalanine on the acquisition of tolerance to the hypothermic effects of ethanol. Psychopharmacology 57:239\u2013242, 1978c.","journal-title":"Psychopharmacology"},{"key":"17_CR8","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1007\/BF00428901","volume":"44","author":"D Frankel","year":"1975","unstructured":"Frankel, D., Khanna, J.M., LeBlanc, A.E., Kalant, H. Effect of p-chlorophenylalanine on the acquisition of tolerance to ethanol and pentobarbital. Psychopharmacologia (Berl.) 44, 247\u2013252, 1975.","journal-title":"Psychopharmacologia (Berl.)"},{"key":"17_CR9","doi-asserted-by":"publisher","first-page":"954","DOI":"10.1139\/y77-128","volume":"55","author":"D Frankel","year":"1977","unstructured":"Frankel, D., Khanna, J.M., Le Blanc, A.E., Kalant, H. Effect of p-chlorophenylalanine on development of cross-tolerance between pentobarbital and ethanol. Can. J. Physiol. Pharmacol. 55: 954\u2013957, 1977.","journal-title":"Can. J. Physiol. Pharmacol"},{"key":"17_CR10","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1515\/bchm2.1957.308.1.9","volume":"308","author":"S Goldschmidt","year":"1957","unstructured":"Goldschmidt, S., Wehr, R. Uber Barbiturate, III. Mitteilung. Der Metabolismus von veronal. Z. Physiol. Chem. 308:9\u201319, 1957.","journal-title":"Z. Physiol. Chem"},{"key":"17_CR11","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/S0022-3565(25)30119-9","volume":"193","author":"IK Ho","year":"1975","unstructured":"Ho, I.K. Brase, D.A., Loh, H.H., Way, E.L. Influence of L-tryptophan on morphine analgesia, tolerance and physical dependence. J. Pharmacol. Exp. Ther. 193:35\u201343, 1975.","journal-title":"J. Pharmacol. Exp. Ther"},{"key":"17_CR12","doi-asserted-by":"publisher","first-page":"331","DOI":"10.1016\/0014-2999(73)90135-0","volume":"21","author":"IK Ho","year":"1973","unstructured":"Ho, I.K., Loh, H.H., Way, E.L. Influence of 5,6-dihydroxytryptamine on morphine tolerance and physical dependence. Europ. J. Pharmacol. 21:331\u2013336, 1973.","journal-title":"Europ. J. Pharmacol."},{"key":"17_CR13","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/S0022-3565(25)29260-6","volume":"182","author":"IK Ho","year":"1972","unstructured":"Ho, I.K., Lu, S.E., Stolman, S., Loh, H.H., Way, E.L. Influence of p-chlorophenylalanine on morphine tolerance and physical dependence and regional brain serotonin turnover studies in morphine tolerant-dependent mice. J. Pharmacol. Exp. Ther. 182; 155\u2013165, 1972.","journal-title":"J. Pharmacol. Exp. Ther"},{"key":"17_CR14","doi-asserted-by":"crossref","unstructured":"Kalant, H., Le Blanc, A.E., Gibbins, R.J., Wilson, A. Acceleration of development of tolerance during repeated cycles of ethanol exposure. Psychopharmacology (in press), 1978.","DOI":"10.1007\/BF00429180"},{"key":"17_CR15","unstructured":"Khanna, J.M., Kalant, H., Mayer, J., Le, A.D., LeBlanc, A.E., Marshman, J. Effect of p-chlorophenylalanine on the acquisition of tolerance to the hypnotic effect of pentobarbital, barbital and ethanol. Submitted for publication (1978)."},{"key":"17_CR16","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1007\/BF00421426","volume":"30","author":"AE Blanc Le","year":"1973","unstructured":"Le Blanc, A.E., Gibbins, R.J., Kalant, H. Behavioral aumentation of tolerance to ethanol in the rat. Psychopharmacologia (Berl.) 30, 117\u2013122, 1973.","journal-title":"Psychopharmacologia (Berl.)"},{"key":"17_CR17","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1016\/S0022-3565(25)28327-6","volume":"168","author":"AE Blanc Le","year":"1969","unstructured":"Le Blanc, A.E., Kalant, H., Gibbins, R.J., Berman, N.D. Acquisition and loss of tolerance to ethanol by the rat. J. Pharmacol. Exp. Ther. 168:244\u2013250, 1969.","journal-title":"J. Pharmacol. Exp. Ther"},{"key":"17_CR18","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1016\/0091-3057(76)90011-3","volume":"4","author":"AE Blanc Le","year":"1976","unstructured":"Le Blanc, A.E., Matsunaga, M., Kalant, H. Effects of frontal polar cortical ablation and cycloheximide on ethanol tolerance in rats. Pharmacol. Biochem. Behav. 4:175\u2013179, 1976.","journal-title":"Pharmacol. Biochem. Behav"},{"key":"17_CR19","doi-asserted-by":"publisher","first-page":"515","DOI":"10.1016\/0006-8993(74)90642-8","volume":"77","author":"JA Pearson","year":"1974","unstructured":"Pearson, J.A., Wills, L., MacDonald, J.F. The effect of p-CPA and lesions of the dorsal raphe nucleus on habituation of the flexor withdrawal reflex. Brain Res. 77:515\u2013520, 1974.","journal-title":"Brain Res"},{"key":"17_CR20","doi-asserted-by":"publisher","first-page":"418","DOI":"10.1038\/263418a0","volume":"263","author":"RF Ritzman","year":"1976","unstructured":"Ritzman, R.F., Tabakoff, B. Dissociation of alcohol tolerance and dependence. Nature 263:418\u2013420, 1976.","journal-title":"Nature"},{"key":"17_CR21","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1007\/978-1-4615-9038-5_11","volume-title":"Alcohol Intoxication and Withdrawal","author":"B Tabakoff","year":"1977","unstructured":"Tabakoff, B., Ritzman, R.F., Hoffman, P.L. Role of catecholamines in the development of tolerance to barbiturates and ethanol. In Alcohol Intoxication and Withdrawal \u2014 IIIb (M.M. Gross, ed.) pp. 155\u2013168. Plenum Press, New York (1977)."},{"key":"17_CR22","first-page":"207","volume":"12","author":"AK Swonger","year":"1970","unstructured":"Swonger, A.K., Chambers, W.F., Rech, R.H. The effects of alterations in brain 5-HT on habituation of the cortical evoked response and the startle response in rats. Pharmacologist 12: 207, 1970.","journal-title":"Pharmacologist"},{"key":"17_CR23","doi-asserted-by":"publisher","first-page":"204","DOI":"10.1007\/BF00401382","volume":"10","author":"SS Tenen","year":"1967","unstructured":"Tenen, S.S. The effects of p-chlorophenylalanine, a serotonin depletor, on avoidance acquisition, pain sensitivity and related behavior in the rat. Psychopharmacologia (Berl.) 10; 204\u2013219, 1967.","journal-title":"Psychopharmacologia (Berl.)"},{"key":"17_CR24","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1007\/BF00421565","volume":"35","author":"HA Tilson","year":"1974","unstructured":"Tilson, H.A., Rech, R.H. The effects of p-chlorophenylalanine on morphine analgesia, tolerance and dependence development in two strains of rats. Psychopharmacologia (Berl.) 35;45\u201360, 1974.","journal-title":"Psychopharmacologia (Berl.)"},{"key":"17_CR25","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1007\/BF00426602","volume":"52","author":"WG Wood","year":"1977","unstructured":"Wood, W.G. Facilitation by dexamethasone of tolerance to ethanol in the rat. Psychopharmacology 52:67\u201372, 1977.","journal-title":"Psychopharmacology"}],"container-title":["Advances in Experimental Medicine and Biology","Biological Effects of Alcohol"],"original-title":[],"link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/978-1-4684-3632-7_17","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T09:12:43Z","timestamp":1746090763000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/978-1-4684-3632-7_17"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1980]]},"ISBN":["9781468436341","9781468436327"],"references-count":25,"URL":"https:\/\/doi.org\/10.1007\/978-1-4684-3632-7_17","relation":{},"ISSN":["0065-2598","2214-8019"],"issn-type":[{"type":"print","value":"0065-2598"},{"type":"electronic","value":"2214-8019"}],"subject":[],"published":{"date-parts":[[1980]]}}}