{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T04:15:49Z","timestamp":1759032949153,"version":"3.40.3"},"publisher-location":"Boston, MA","reference-count":18,"publisher":"Springer US","isbn-type":[{"type":"print","value":"9781468456752"},{"type":"electronic","value":"9781468456738"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1989]]},"DOI":"10.1007\/978-1-4684-5673-8_27","type":"book-chapter","created":{"date-parts":[[2012,7,10]],"date-time":"2012-07-10T16:04:52Z","timestamp":1341936292000},"page":"165-172","source":"Crossref","is-referenced-by-count":14,"title":["Hypoxanthine Accumulation and Dopamine Depletion in Lesch-Nyhan Disease"],"prefix":"10.1007","author":[{"given":"Roberta M.","family":"Palmour","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Timothy W.","family":"Heshka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frank R.","family":"Ervin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"27_CR1","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1016\/S0022-3565(25)24464-0","volume":"244","author":"H Criswell","year":"1988","unstructured":"Criswell, H., Mueller, R. A. and Breese, G. R., Assisment of purine-dopamine interactions in 6-hydroxydopamine-lesioned rats, J. Pharmacol. Exp. Therap. 244: 493 (1988).","journal-title":"J. Pharmacol. Exp. Therap."},{"key":"27_CR2","doi-asserted-by":"publisher","first-page":"535","DOI":"10.1016\/0091-3057(83)90131-4","volume":"19","author":"BB Fredholm","year":"1983","unstructured":"Fredholm, B. B., Herrera-Marschitz, M., Jonzon, B., Lindstrom, K. and Ungerstedt, U., On the mechanism by which methylxanthines enhance apomorphine-induced rotation behavior in the rat, Pharmacol. Biochem. Behav. 19: 535 (1983).","journal-title":"Pharmacol. Biochem. Behav."},{"key":"27_CR3","first-page":"214","volume":"1","author":"AE Garrod","year":"1908","unstructured":"Garrod, A. E., Inborn errors of metabolism (Croonian Lectures), Lancet 1: 73, 142, 214 (1908).","journal-title":"Lancet"},{"key":"27_CR4","doi-asserted-by":"publisher","first-page":"338","DOI":"10.1016\/S0140-6736(85)91107-9","volume":"1","author":"M Goldstein","year":"1985","unstructured":"Goldstein, M., Anderson, L.T., Reuben, R. and Dancis, J., Self-mutilation in Lesch-Nyhan disease is caused by dopaminergic denervation, Lancet 1: 338 (1985).","journal-title":"Lancet"},{"key":"27_CR5","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1126\/science.7123218","volume":"218","author":"RD Green","year":"1982","unstructured":"Green, R. D., Proudfit, H. K., and Yeung, S. H., Modulation of striatal dopaminergic function by local injection of 5\u2032-N-ethylcarboxamide adenosine, Science, 218: 58 (1982).","journal-title":"Science"},{"key":"27_CR6","volume-title":"The Metabolic Basis of Inherited Disease","author":"WN Kelley","year":"1983","unstructured":"Kelley W. N. and Wyngaarden J. B. (1983) Clinical syndromes associated with HPRT deficiency, in The Metabolic Basis of Inherited Disease, 5th edition, J. B. Stanbury, J. B. Wyngaarden, D. S. Frederickson, J. L. Goldstein, and M. S. Brown, eds., McGraw-Hill, New York (1983).","edition":"5"},{"key":"27_CR7","volume-title":"The Metabolic Basis of Inherited Disease","author":"WE Knox","year":"1972","unstructured":"Knox, W. E., Phenylketonuria, in The Metabolic Basis of Inherited Disease, 3rd ed., J. B. Stanbury, J. B. Wyngaarden and D. S. Fredrickson, eds., McGraw Hill, New York, (1972).","edition":"3"},{"key":"27_CR8","first-page":"2237","volume":"49","author":"AM Krustolovic","year":"1977","unstructured":"Krustolovic, A. M., Brown, P. R. and Rosle, D. M., Identification of nucleosides and bases in serum and plasma samples by reverse phase HPLC, Anal. Biochem. 49: 2237 (1977).","journal-title":"Anal. Biochem"},{"key":"27_CR9","doi-asserted-by":"publisher","first-page":"1106","DOI":"10.1056\/NEJM198111053051902","volume":"305","author":"KG Lloyd","year":"1981","unstructured":"Lloyd, K. G., Hornykiewicz, O., Davidson, L., Shannak, K., Farley, I., Goldstein, M., Shibuya, M., Kelley, W. N., and Fox, I. H., Biochemical evidence of dysfunction of brain neurotransmitters in the Lesch-Nyhan syndrome. N. Engl. J. Med., 305: 1106 (1981).","journal-title":"N. Engl. J. Med."},{"key":"27_CR10","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1007\/BF01543464","volume":"6","author":"WL Nyhan","year":"1971","unstructured":"Nyhan, W. L., Behavior in the Lesch-Nyhan syndrome, J. Autism child Schizophr., 6: 235 (1971).","journal-title":"J. Autism child Schizophr"},{"key":"27_CR11","unstructured":"Palmour, R. M., Schucher, K., Pacheco, P., and Ervin, F. R., Dopamine depletion and self-mutilation in the rat: A model for Lesch-Nyhan disease, Pharmacol. Biochem. Behav., in press."},{"key":"27_CR12","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/S0022-3565(25)24268-9","volume":"244","author":"NM Porter","year":"1988","unstructured":"Porter, N. M., Radulovacki, M. and Green, R. D., Desensitization of adenosine and dopamine receptors in rat brain after treatment with adenosine analogs, J. Pharmacol. Exp. Therap. 244: 218 (1988).","journal-title":"J. Pharmacol. Exp. Therap"},{"key":"27_CR13","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1001\/jama.1967.03130160049007","volume":"202","author":"FM Rosenbloom","year":"1967","unstructured":"Rosenbloom, F. M., Kelley, W. N., Miller, J., Henderson, J. F. and Seegmiller, J. E., Inherited disorder of purine metabolism: Correlation between central nervous system dysfunction and biochemical defects J. Amer. Med. Assoc. 202: 175 (1967).","journal-title":"J. Amer. Med. Assoc."},{"key":"27_CR14","volume-title":"Gout and hyperuricemia, in Metabolic Control and Disease","author":"JE Seegmiller","year":"1981","unstructured":"Seegmiller, J. E., Gout and hyperuricemia, in Metabolic Control and Disease, P. K. Bondy and L. E. Rosenberg, eds., W. B. Saunders, Philadelphia (1981)."},{"key":"27_CR15","doi-asserted-by":"publisher","first-page":"907","DOI":"10.1212\/WNL.35.6.907","volume":"35","author":"FS Silverstein","year":"1985","unstructured":"Silverstein, F.S., Johnston, M.V., Hutchinson, R.J. and Edwards, N.L., Lesch-Nyhan syndrome: CSF neurotransmitter abnormalities. Neurol 35: 907 (1985).","journal-title":"Neurol"},{"key":"27_CR16","doi-asserted-by":"publisher","first-page":"486","DOI":"10.1016\/0006-8993(70)90187-3","volume":"24","author":"U Ungerstedt","year":"1970","unstructured":"Ungerstedt, U., and Arbuthnott, G., Quantitative recording of rotational behaviour in rats after 6-OH dopamine lesions of the rat nigrostriatal dopamine system, Brain Res 24: 486 (1970).","journal-title":"Brain Res"},{"key":"27_CR17","first-page":"43","volume":"201","author":"RWE Watts","year":"1982","unstructured":"Watts, R. W. E., Spellacy, E., Gibbs, D. A., Allsop, J., McKeran, R. O. and Slavin, G. E., Clinical, post-mortem, biochemical and therapeutic observations on the Lesch-Nyhan Syndrome with particular reference to the neurological manifestations, Q. J. Med., 201: 43 (1982).","journal-title":"Q. J. Med."},{"key":"27_CR18","doi-asserted-by":"publisher","first-page":"1449","DOI":"10.1111\/j.1471-4159.1981.tb00586.x","volume":"36","author":"BHC Westerink","year":"1981","unstructured":"Westerink, B. H. C. and Mulder, T. B. A., Determination of picomole amounts of DA, NE, DOPAC, HVA and HIAA using HPLV with a novel type of electrochemical detection. J Neurochem 36: 1449 (1981).","journal-title":"J Neurochem"}],"container-title":["Advances in Experimental Medicine and Biology","Purine and Pyrimidine Metabolism in Man VI"],"original-title":[],"link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/978-1-4684-5673-8_27.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,3]],"date-time":"2025-04-03T19:51:21Z","timestamp":1743709881000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/978-1-4684-5673-8_27"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1989]]},"ISBN":["9781468456752","9781468456738"],"references-count":18,"URL":"https:\/\/doi.org\/10.1007\/978-1-4684-5673-8_27","relation":{},"ISSN":["0065-2598"],"issn-type":[{"type":"print","value":"0065-2598"}],"subject":[],"published":{"date-parts":[[1989]]}}}