{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,12]],"date-time":"2026-11-12T17:11:36Z","timestamp":1794503496522,"version":"4.9.1"},"publisher-location":"New York, NY","reference-count":20,"publisher":"Springer New York","isbn-type":[{"value":"9781493929160","type":"print"},{"value":"9781493929177","type":"electronic"}],"license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015]]},"DOI":"10.1007\/978-1-4939-2917-7_14","type":"book-chapter","created":{"date-parts":[[2015,8,18]],"date-time":"2015-08-18T07:59:56Z","timestamp":1439884796000},"page":"189-196","source":"Crossref","is-referenced-by-count":0,"title":["VEGF Gene Transfer to the Utero-Placental Circulation of Pregnant Guinea Pigs to Enhance Fetal Growth"],"prefix":"10.1007","author":[{"given":"Vedanta","family":"Mehta","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David J.","family":"Carr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Swanson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna L.","family":"David","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"issue":"Suppl 1","key":"14_CR1","doi-asserted-by":"publisher","first-page":"S55","DOI":"10.1016\/S0301-2115(03)00173-8","volume":"110","author":"U Lang","year":"2003","unstructured":"Lang U, Baker RS, Braems G, Zygmunt M, Kunzel W et al (2003) Uterine blood flow \u2013 a determinant of fetal growth. Eur J Obstet Gynecol Reprod Biol 110(Suppl 1):S55\u2013S61","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"14_CR2","doi-asserted-by":"publisher","first-page":"270","DOI":"10.1097\/00003081-200606000-00009","volume":"49","author":"DJ Barker","year":"2006","unstructured":"Barker DJ (2006) Adult consequences of fetal growth restriction. Clin Obstet Gynecol 49:270\u2013283","journal-title":"Clin Obstet Gynecol"},{"key":"14_CR3","doi-asserted-by":"publisher","first-page":"722","DOI":"10.1034\/j.1600-0412.2003.00220.x","volume":"82","author":"T Naicker","year":"2003","unstructured":"Naicker T, Khedun SM, Moodley J, Pijnenborg R (2003) Quantitative analysis of trophoblast invasion in preeclampsia. Acta Obstet Gynecol Scand 82:722\u2013729","journal-title":"Acta Obstet Gynecol Scand"},{"key":"14_CR4","doi-asserted-by":"publisher","first-page":"1143","DOI":"10.1038\/labinvest.3780326","volume":"81","author":"F Reister","year":"2001","unstructured":"Reister F, Frank HG, Kingdom JC, Heyl W, Kaufmann P et al (2001) Macrophage-induced apoptosis limits endovascular trophoblast invasion in the uterine wall of preeclamptic women. Lab Invest 81:1143\u20131152","journal-title":"Lab Invest"},{"key":"14_CR5","doi-asserted-by":"publisher","first-page":"572","DOI":"10.1016\/j.ajog.2004.08.015","volume":"192","author":"SS Ong","year":"2005","unstructured":"Ong SS, Baker PN, Mayhew TM, Dunn WR (2005) Remodeling of myometrial radial arteries in preeclampsia. Am J Obstet Gynecol 192:572\u2013579","journal-title":"Am J Obstet Gynecol"},{"key":"14_CR6","doi-asserted-by":"publisher","first-page":"2550","DOI":"10.1210\/jc.2004-1831","volume":"90","author":"M Wareing","year":"2005","unstructured":"Wareing M, Myers JE, O\u2019Hara M, Baker PN (2005) Sildenafil citrate (Viagra) enhances vasodilatation in fetal growth restriction. J Clin Endocrinol Metab 90:2550\u20132555","journal-title":"J Clin Endocrinol Metab"},{"key":"14_CR7","doi-asserted-by":"publisher","first-page":"653","DOI":"10.1038\/nm0603-653","volume":"9","author":"P Carmeliet","year":"2003","unstructured":"Carmeliet P (2003) Angiogenesis in health and disease. Nat Med 9:653\u2013660","journal-title":"Nat Med"},{"key":"14_CR8","doi-asserted-by":"publisher","first-page":"1512","DOI":"10.1161\/01.ATV.20.6.1512","volume":"20","author":"I Zachary","year":"2000","unstructured":"Zachary I, Mathur A, Yla-Herttuala S, Martin J (2000) Vascular protection: a novel nonangiogenic cardiovascular role for vascular endothelial growth factor. Arterioscler Thromb Vasc Biol 20:1512\u20131520","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"14_CR9","first-page":"H586","volume":"265","author":"DD Ku","year":"1993","unstructured":"Ku DD, Zaleski JK, Liu S, Brock TA (1993) Vascular endothelial growth factor induces EDRF-dependent relaxation in coronary arteries. Am J Physiol 265:H586\u2013H592","journal-title":"Am J Physiol"},{"key":"14_CR10","doi-asserted-by":"publisher","first-page":"1261","DOI":"10.1161\/01.CIR.98.13.1261","volume":"98","author":"S Takeshita","year":"1998","unstructured":"Takeshita S, Isshiki T, Ochiai M, Eto K, Mori H et al (1998) Endothelium-dependent relaxation of collateral microvessels after intramuscular gene transfer of vascular endothelial growth factor in a rat model of hindlimb ischemia. Circulation 98:1261\u20131263","journal-title":"Circulation"},{"key":"14_CR11","doi-asserted-by":"publisher","first-page":"1737","DOI":"10.1089\/hum.1997.8.15-1737","volume":"8","author":"M Laitinen","year":"1997","unstructured":"Laitinen M, Zachary I, Breier G, Pakkanen T, Hakkinen T et al (1997) VEGF gene transfer reduces intimal thickening via increased production of nitric oxide in carotid arteries. Hum Gene Ther 8:1737\u20131744","journal-title":"Hum Gene Ther"},{"key":"14_CR12","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1016\/S0014-5793(97)01481-6","volume":"420","author":"C Wheeler-Jones","year":"1997","unstructured":"Wheeler-Jones C, Abu-Ghazaleh R, Cospedal R, Houliston RA, Martin J et al (1997) Vascular endothelial growth factor stimulates prostacyclin production and activation of cytosolic phospholipase A2 in endothelial cells via p42\/p44 mitogen-activated protein kinase. FEBS Lett 420:28\u201332","journal-title":"FEBS Lett"},{"key":"14_CR13","doi-asserted-by":"publisher","first-page":"1405","DOI":"10.1016\/S0002-9440(10)62567-9","volume":"160","author":"Y Zhou","year":"2002","unstructured":"Zhou Y, McMaster M, Woo K, Janatpour M, Perry J et al (2002) Vascular endothelial growth factor ligands and receptors that regulate human cytotrophoblast survival are dysregulated in severe preeclampsia and hemolysis, elevated liver enzymes, and low platelets syndrome. Am J Pathol 160:1405\u20131423","journal-title":"Am J Pathol"},{"key":"14_CR14","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1002\/dvdy.10291","volume":"227","author":"M Hemberger","year":"2003","unstructured":"Hemberger M, Nozaki T, Masutani M, Cross JC (2003) Differential expression of angiogenic and vasodilatory factors by invasive trophoblast giant cells depending on depth of invasion. Dev Dyn 227:185\u2013191","journal-title":"Dev Dyn"},{"key":"14_CR15","doi-asserted-by":"publisher","first-page":"1668","DOI":"10.1016\/j.ajog.2006.03.065","volume":"195","author":"MD Savvidou","year":"2006","unstructured":"Savvidou MD, Yu CK, Harland LC, Hingorani AD, Nicolaides KH (2006) Maternal serum concentration of soluble fms-like tyrosine kinase 1 and vascular endothelial growth factor in women with abnormal uterine artery Doppler and in those with fetal growth restriction. Am J Obstet Gynecol 195:1668\u20131673","journal-title":"Am J Obstet Gynecol"},{"key":"14_CR16","doi-asserted-by":"publisher","first-page":"785","DOI":"10.1016\/S0140-6736(05)71003-5","volume":"365","author":"B Sibai","year":"2005","unstructured":"Sibai B, Dekker G, Kupferminc M (2005) Pre-eclampsia. Lancet 365:785\u2013799","journal-title":"Lancet"},{"key":"14_CR17","doi-asserted-by":"publisher","first-page":"666","DOI":"10.1095\/biolreprod64.2.666","volume":"64","author":"LA Hefler","year":"2001","unstructured":"Hefler LA, Reyes CA, O\u2019Brien WE, Gregg AR (2001) Perinatal development of endothelial nitric oxide synthase-deficient mice. Biol Reprod 64:666\u2013673","journal-title":"Biol Reprod"},{"key":"14_CR18","first-page":"5","volume":"53","author":"P Kaufmann","year":"1977","unstructured":"Kaufmann P, Davidoff M (1977) The guinea-pig placenta. Adv Anat Embryol Cell Biol 53:5\u201391","journal-title":"Adv Anat Embryol Cell Biol"},{"key":"14_CR19","doi-asserted-by":"publisher","first-page":"2436","DOI":"10.1161\/01.CIR.0000145138.25577.F1","volume":"110","author":"R Khurana","year":"2004","unstructured":"Khurana R, Zhuang Z, Bhardwaj S, Murakami M, De Muinck E et al (2004) Angiogenesis-dependent and independent phases of intimal hyperplasia. Circulation 110:2436\u20132443","journal-title":"Circulation"},{"key":"14_CR20","doi-asserted-by":"publisher","first-page":"1383","DOI":"10.1161\/01.ATV.0000168415.33812.51","volume":"25","author":"CM Mallawaarachchi","year":"2005","unstructured":"Mallawaarachchi CM, Weissberg PL, Siow RC (2005) Smad7 gene transfer attenuates adventitial cell migration and vascular remodeling after balloon injury. Arterioscler Thromb Vasc Biol 25:1383\u20131387","journal-title":"Arterioscler Thromb Vasc Biol"}],"container-title":["Methods in Molecular Biology","VEGF Signaling"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/978-1-4939-2917-7_14","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,21]],"date-time":"2023-02-21T02:50:39Z","timestamp":1676947839000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/978-1-4939-2917-7_14"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015]]},"ISBN":["9781493929160","9781493929177"],"references-count":20,"URL":"https:\/\/doi.org\/10.1007\/978-1-4939-2917-7_14","relation":{"is-part-of":[{"id-type":"doi","id":"https:\/\/doi.org\/10.1007\/978-1-4939-2917-7","asserted-by":"object"}]},"ISSN":["1064-3745","1940-6029"],"issn-type":[{"value":"1064-3745","type":"print"},{"value":"1940-6029","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015]]}}}