{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,12]],"date-time":"2026-11-12T19:49:47Z","timestamp":1794512987756,"version":"4.9.1"},"publisher-location":"New York, NY","reference-count":12,"publisher":"Springer New York","isbn-type":[{"value":"9781493934423","type":"print"},{"value":"9781493934447","type":"electronic"}],"license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2016]]},"DOI":"10.1007\/978-1-4939-3444-7_24","type":"book-chapter","created":{"date-parts":[[2016,1,28]],"date-time":"2016-01-28T05:29:44Z","timestamp":1453958984000},"page":"289-302","source":"Crossref","is-referenced-by-count":1,"title":["Intracellular Delivery of Fluorescently Labeled Polysaccharide Nanoparticles to Cultured Breast Cancer Cells"],"prefix":"10.1007","author":[{"given":"Derek","family":"Rammelkamp","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiyi","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yizhi","family":"Meng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2016,1,29]]},"reference":[{"key":"24_CR1","doi-asserted-by":"publisher","first-page":"815","DOI":"10.1038\/nnano.2011.166","volume":"6","author":"H Cabral","year":"2011","unstructured":"Cabral H, Matsumoto Y, Mizuno K et al (2011) Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size. Nat Nanotechnol 6:815\u2013823","journal-title":"Nat Nanotechnol"},{"key":"24_CR2","doi-asserted-by":"publisher","first-page":"751","DOI":"10.1038\/nnano.2007.387","volume":"2","author":"D Peer","year":"2007","unstructured":"Peer D, Karp JM, Hong S et al (2007) Nanocarriers as an emerging platform for cancer therapy. Nat Nanotechnol 2:751\u2013760","journal-title":"Nat Nanotechnol"},{"key":"24_CR3","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1016\/j.jconrel.2010.04.004","volume":"146","author":"K Kim","year":"2010","unstructured":"Kim K, Kim JH, Park H et al (2010) Tumor-homing multifunctional nanoparticles for cancer theragnosis: simultaneous diagnosis, drug delivery, and therapeutic monitoring. J Control Release 146:219\u2013227","journal-title":"J Control Release"},{"key":"24_CR4","doi-asserted-by":"publisher","first-page":"3477","DOI":"10.1016\/j.biomaterials.2008.04.036","volume":"29","author":"M Morille","year":"2008","unstructured":"Morille M, Passirani C, Vonarbourg A et al (2008) Progress in developing cationic vectors for non-viral systemic gene therapy against cancer. Biomaterials 29:3477\u20133496","journal-title":"Biomaterials"},{"key":"24_CR5","doi-asserted-by":"publisher","first-page":"1310","DOI":"10.1158\/1078-0432.CCR-07-1441","volume":"14","author":"K Cho","year":"2008","unstructured":"Cho K, Wang X, Nie S et al (2008) Therapeutic nanoparticles for drug delivery in cancer. Clin Cancer Res 14:1310\u20131316","journal-title":"Clin Cancer Res"},{"key":"24_CR6","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1080\/10611860701539584","volume":"15","author":"K Greish","year":"2007","unstructured":"Greish K (2007) Enhanced permeability and retention of macromolecular drugs in solid tumors: a royal gate for targeted anticancer nanomedicines. J Drug Target 15:457\u2013464","journal-title":"J Drug Target"},{"key":"24_CR7","first-page":"6387","volume":"46","author":"Y Matsumura","year":"1986","unstructured":"Matsumura Y, Maeda H (1986) A new concept for macromolecular therapeutics in cancer-chemotherapy - mechanisms of tumoritropic accumulation of proteins and the antitumor agent SMANCS. Cancer Res 46:6387\u20136392","journal-title":"Cancer Res"},{"key":"24_CR8","doi-asserted-by":"publisher","first-page":"797","DOI":"10.1021\/bc100070g","volume":"21","author":"H Maeda","year":"2010","unstructured":"Maeda H (2010) Tumor-selective delivery of macromolecular drugs via the EPR effect: background and future prospects. Bioconjug Chem 21:797\u2013802","journal-title":"Bioconjug Chem"},{"key":"24_CR9","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1016\/j.jconrel.2012.07.013","volume":"164","author":"S Taurin","year":"2012","unstructured":"Taurin S, Nehoff H, Greish K (2012) Anticancer nanomedicine and tumor vascular permeability; Where is the missing link? J Control Release 164:265\u2013275","journal-title":"J Control Release"},{"key":"24_CR10","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1124\/pr.58.1.8","volume":"58","author":"IA Khalil","year":"2006","unstructured":"Khalil IA, Kogure K, Akita H et al (2006) Uptake pathways and subsequent intracellular trafficking in nonviral gene delivery. Pharmacol Rev 58:32\u201345","journal-title":"Pharmacol Rev"},{"key":"24_CR11","doi-asserted-by":"publisher","first-page":"6708","DOI":"10.1158\/0008-5472.CAN-06-3803","volume":"67","author":"CB Zeng","year":"2007","unstructured":"Zeng CB, Vangveravong S, Xu JB et al (2007) Subcellular localization of sigma-2 receptors in breast cancer cells using two-photon and confocal microscopy. Cancer Res 67:6708\u20136716","journal-title":"Cancer Res"},{"key":"24_CR12","first-page":"1","volume":"1","author":"A Chin","year":"2014","unstructured":"Chin A, Suarato G, Meng Y (2014) Evaluation of physicochemical characteristics of hydrophobically modified glycol chitosan nanoparticles and their biocompatibility in murine osteosarcoma and osteoblast-like cells. J Nanotech Smart Mater 1:1\u20137","journal-title":"J Nanotech Smart Mater"}],"container-title":["Methods in Molecular Biology","Breast Cancer"],"original-title":[],"link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/978-1-4939-3444-7_24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T07:58:15Z","timestamp":1559375895000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/978-1-4939-3444-7_24"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"ISBN":["9781493934423","9781493934447"],"references-count":12,"URL":"https:\/\/doi.org\/10.1007\/978-1-4939-3444-7_24","relation":{"is-part-of":[{"id-type":"doi","id":"https:\/\/doi.org\/10.1007\/978-1-4939-3444-7","asserted-by":"object"}]},"ISSN":["1064-3745","1940-6029"],"issn-type":[{"value":"1064-3745","type":"print"},{"value":"1940-6029","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016]]}}}