{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T15:00:16Z","timestamp":1786978816497,"version":"build-2736575974"},"publisher-location":"New York, NY","reference-count":19,"publisher":"Springer New York","isbn-type":[{"value":"9781493971947","type":"print"},{"value":"9781493971961","type":"electronic"}],"license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017]]},"DOI":"10.1007\/978-1-4939-7196-1_30","type":"book-chapter","created":{"date-parts":[[2017,8,13]],"date-time":"2017-08-13T10:24:07Z","timestamp":1502619847000},"page":"403-416","source":"Crossref","is-referenced-by-count":18,"title":["Laboratory Testing for von Willebrand Factor Antigen (VWF:Ag)"],"prefix":"10.1007","author":[{"given":"Emmanuel J.","family":"Favaloro","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soma","family":"Mohammed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00fcrgen","family":"Patzke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,8,14]]},"reference":[{"key":"30_CR1","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1055\/s-0031-1280567","volume":"37","author":"EJ Favaloro","year":"2011","unstructured":"Favaloro EJ (2011) Von Willebrand disease: local diagnosis and management of a globally distributed bleeding disorder. Semin Thromb Hemost 37:425\u2013426","journal-title":"Semin Thromb Hemost"},{"key":"30_CR2","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1055\/s-0033-1334867","volume":"39","author":"AB Federici","year":"2013","unstructured":"Federici AB, Budde U, Castaman G, Rand JH, Tiede A (2013) Current diagnostic and therapeutic approaches to patients with acquired von Willebrand syndrome: a 2013 update. Semin Thromb Hemost 39:191\u2013201","journal-title":"Semin Thromb Hemost"},{"key":"30_CR3","first-page":"17","volume":"40","author":"A Yee","year":"2014","unstructured":"Yee A, Kretz CA (2014) Von Willebrand factor: form for function. Semin Thromb Hemost 40:17\u201327","journal-title":"Semin Thromb Hemost"},{"key":"30_CR4","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1517\/21678707.2015.1066245","volume":"3","author":"EJ Favaloro","year":"2015","unstructured":"Favaloro EJ (2015) Recent advances in laboratory-aided diagnosis of von Willebrand disease. Expert Opin Orphan Drugs 3:975\u2013995","journal-title":"Expert Opin Orphan Drugs"},{"key":"30_CR5","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.pathol.2016.03.001","volume":"48","author":"EJ Favaloro","year":"2016","unstructured":"Favaloro EJ, Pasalic L, Curnow J (2016) Laboratory tests used to help diagnose von Willebrand disease: an update. Pathology 48:303\u2013318","journal-title":"Pathology"},{"key":"30_CR6","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1055\/s-0034-1383546","volume":"40","author":"EJ Favaloro","year":"2014","unstructured":"Favaloro EJ (2014) Diagnosing von Willebrand disease: a short history of laboratory milestones and innovations, plus current status, challenges, and solutions. Semin Thromb Hemost 40:551\u2013570","journal-title":"Semin Thromb Hemost"},{"key":"30_CR7","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1111\/ijlh.12019","volume":"35","author":"Y Ni","year":"2013","unstructured":"Ni Y, Nesrallah J, Agnew M, Geske FJ, Favaloro EJ (2013) Establishment and characterization of a new and stable collagen-binding assay for the assessment of von Willebrand factor activity. Int J Lab Hematol 35:170\u2013176","journal-title":"Int J Lab Hematol"},{"key":"30_CR8","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1055\/s-0032-1315961","volume":"38","author":"G Lippi","year":"2012","unstructured":"Lippi G, Salvagno GL, Montagnana M, Lima-Oliveira G, Guidi GC, Favaloro EJ (2012) Quality standards for sample collection in coagulation testing. Semin Thromb Hemost 38:565\u2013575","journal-title":"Semin Thromb Hemost"},{"key":"30_CR9","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1055\/s-0032-1319768","volume":"38","author":"DM Adcock Funk","year":"2012","unstructured":"Adcock Funk DM, Lippi G, Favaloro EJ (2012) Quality standards for sample processing, transportation, and storage in hemostasis testing. Semin Thromb Hemost 38:576\u2013585","journal-title":"Semin Thromb Hemost"},{"key":"30_CR10","volume-title":"Collection, transport, and processing of blood specimens for testing plasma-based coagulation assays and molecular hemostasis assays; Approved guideline 5th ed CLSI document H21\u2013A5","author":"Clinical and Laboratory Standards Institute","year":"2008","unstructured":"Clinical and Laboratory Standards Institute (2008) Collection, transport, and processing of blood specimens for testing plasma-based coagulation assays and molecular hemostasis assays; Approved guideline 5th ed CLSI document H21\u2013A5. Clinical and Laboratory Standards Institute, Wayne, PA"},{"key":"30_CR11","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1309\/E4947DG48TVY19C2","volume":"122","author":"EJ Favaloro","year":"2004","unstructured":"Favaloro EJ, Soltani S, McDonald J (2004) Potential laboratory misdiagnosis of haemophilia and von Willebrand Disorder due to cold activation of blood samples for testing. Am J Clin Pathol 122:686\u2013692","journal-title":"Am J Clin Pathol"},{"key":"30_CR12","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1097\/01.mbc.0000198990.16598.85","volume":"17","author":"M B\u00f6hm","year":"2006","unstructured":"B\u00f6hm M, T\u00e4schner S, Kretzschmar E, Gerlach R, Favaloro EJ, Scharrer I (2006) Cold storage of citrated whole blood induces drastic time- dependent losses in factor VIII and von Willebrand factor: Potential for misdiagnosis of haemophilia and von Willebrand\u2019s disease. Blood Coagul Fibrinolysis 17:39\u201345","journal-title":"Blood Coagul Fibrinolysis"},{"key":"30_CR13","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1097\/00001721-200106000-00002","volume":"12","author":"B Woodhams","year":"2001","unstructured":"Woodhams B, Girardot O, Blanco MJ, Colesse G, Gourmelin Y (2001) Stability of coagulation proteins in frozen plasma. Blood Coagul Fibrinolysis 12:229\u2013236","journal-title":"Blood Coagul Fibrinolysis"},{"key":"30_CR14","doi-asserted-by":"crossref","first-page":"1292","DOI":"10.1016\/j.thromres.2014.09.024","volume":"134","author":"EJ Favaloro","year":"2014","unstructured":"Favaloro EJ, Mohammed S (2014) Towards improved diagnosis of von Willebrand disease: comparative evaluations of several automated von Willebrand factor antigen and activity assays. Thromb Res 134:1292\u20131300","journal-title":"Thromb Res"},{"key":"30_CR15","series-title":"CLSI Document EP28-A3C","volume-title":"Defining, establishing, and verifying reference intervals in the clinical laboratory: approved guideline","author":"Clinical and Laboratory Standards Institute","year":"2008","unstructured":"Clinical and Laboratory Standards Institute (2008) Defining, establishing, and verifying reference intervals in the clinical laboratory: approved guideline, CLSI Document EP28-A3C, 3rd edn. Clinical and Laboratory Standards Institute, Wayne, PA","edition":"3"},{"key":"30_CR16","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1309\/W76QF806CE80CL2T","volume":"124","author":"EJ Favaloro","year":"2005","unstructured":"Favaloro EJ, Soltani S, McDonald J, Grezchnik E, Easton L, Favaloro JWC (2005) Reassessment of ABO-blood group, gender and age on laboratory parameters used to diagnose von Willebrand Disorder (VWD): Potential influence on the diagnosis versus the potential association with risk of thrombosis. Am J Clin Pathol 124:910\u2013917","journal-title":"Am J Clin Pathol"},{"key":"30_CR17","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1055\/s-0034-1384631","volume":"40","author":"EJ Favaloro","year":"2014","unstructured":"Favaloro EJ, Franchini M, Lippi G (2014) Aging hemostasis: changes to laboratory markers of hemostasis as we age-a narrative review. Semin Thromb Hemost 40:621\u2013633","journal-title":"Semin Thromb Hemost"},{"key":"30_CR18","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1111\/j.1365-2516.2007.01643.x","volume":"14","author":"WL Nichols","year":"2008","unstructured":"Nichols WL, Hultin MB, James AH, Manco-Johnson MJ, Montgomery RR, Ortel TL, Rick ME et al (2008) von Willebrand disease (VWD): evidence-based diagnosis and management guidelines, the National Heart, Lung, and Blood Institute (NHLBI) Expert Panel report (USA). Haemophilia 14:171\u2013232","journal-title":"Haemophilia"},{"key":"30_CR19","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1111\/bjh.13064","volume":"167","author":"MA Laffan","year":"2014","unstructured":"Laffan MA, Lester W, O'Donnell JS, Will A, Tait RC, Goodeve A, Millar CM, Keeling DM (2014) The diagnosis and management of von Willebrand disease: a United Kingdom Haemophilia Centre Doctors Organization guideline approved by the British Committee for Standards in Haematology. Br J Haematol 167:453\u2013465","journal-title":"Br J Haematol"}],"container-title":["Methods in Molecular Biology","Hemostasis and Thrombosis"],"original-title":[],"link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/978-1-4939-7196-1_30","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,8,13]],"date-time":"2017-08-13T10:29:31Z","timestamp":1502620171000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/978-1-4939-7196-1_30"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017]]},"ISBN":["9781493971947","9781493971961"],"references-count":19,"URL":"https:\/\/doi.org\/10.1007\/978-1-4939-7196-1_30","relation":{},"ISSN":["1064-3745","1940-6029"],"issn-type":[{"value":"1064-3745","type":"print"},{"value":"1940-6029","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017]]}}}