{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,13]],"date-time":"2026-11-13T07:34:13Z","timestamp":1794555253706,"version":"4.9.1"},"publisher-location":"New York, NY","reference-count":25,"publisher":"Springer New York","isbn-type":[{"value":"9781493974979","type":"print"},{"value":"9781493974986","type":"electronic"}],"license":[{"start":{"date-parts":[[2017,12,2]],"date-time":"2017-12-02T00:00:00Z","timestamp":1512172800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018]]},"DOI":"10.1007\/978-1-4939-7498-6_23","type":"book-chapter","created":{"date-parts":[[2017,12,1]],"date-time":"2017-12-01T07:14:30Z","timestamp":1512112470000},"page":"295-304","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Co-culture of H295R Adrenocortical Carcinoma and BeWo Choriocarcinoma Cells to Study Feto-placental Interactions: Focus on Estrogen Biosynthesis"],"prefix":"10.1007","author":[{"given":"Andr\u00e9e-Anne Hudon","family":"Thibeault","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. Thomas","family":"Sanderson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cathy","family":"Vaillancourt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,12,2]]},"reference":[{"key":"23_CR1","first-page":"5488","volume":"50","author":"AF Gazdar","year":"1990","unstructured":"Gazdar AF, Oie HK, Shackleton CH, Chen TR, Triche TJ, Myers CE, Chrousos GP, Brennan MF, Stein CA, Larocca RV (1990) Establishment and characterization of a human adrenocortical carcinoma cell-line that expresses multiple pathways of steroid-biosynthesis. Cancer Res 50:5488\u20135496","journal-title":"Cancer Res"},{"key":"23_CR2","doi-asserted-by":"publisher","first-page":"1380","DOI":"10.1016\/j.tiv.2009.07.028","volume":"23","author":"MS Poulsen","year":"2009","unstructured":"Poulsen MS, Rytting E, Mose T, Knudsen LE (2009) Modeling placental transport: correlation of in vitro BeWo cell permeability and ex vivo human placental perfusion. Toxicol In Vitro 23:1380\u20131386","journal-title":"Toxicol In Vitro"},{"key":"23_CR3","doi-asserted-by":"publisher","first-page":"1623","DOI":"10.1124\/dmd.110.033571","volume":"10","author":"C Prouillac","year":"2010","unstructured":"Prouillac C, Lecoeur S (2010) The role of the placenta in fetal exposure to xenobiotics: importance of membrane transporters and human models for transfer studies. Drug Metab Dispos 10:1623\u20131235","journal-title":"Drug Metab Dispos"},{"key":"23_CR4","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1016\/S0928-0987(99)00031-7","volume":"8","author":"KL Audus","year":"1999","unstructured":"Audus KL (1999) Controlling drug delivery across the placenta. Eur J Pharm Sci 8:161\u2013165","journal-title":"Eur J Pharm Sci"},{"key":"23_CR5","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1289\/ehp.1307518","volume":"122","author":"AA Hudon Thibeault","year":"2014","unstructured":"Hudon Thibeault AA, Deroy K, Vaillancourt C, Sanderson JT (2014) A unique co-culture model for fundamental and applied studies of human fetoplacental steroidogenesis and interference by environmental chemicals. Environ Health Perspect 122:371\u2013377","journal-title":"Environ Health Perspect"},{"key":"23_CR6","doi-asserted-by":"publisher","first-page":"545","DOI":"10.1387\/ijdb.082771lm","volume":"54","author":"L Myatt","year":"2010","unstructured":"Myatt L, Sun K (2010) Role of fetal membranes in signaling of fetal maturation and parturition. Int J Dev Biol 54:545\u2013553","journal-title":"Int J Dev Biol"},{"key":"23_CR7","doi-asserted-by":"publisher","first-page":"144","DOI":"10.1177\/107155769800500307","volume":"5","author":"JS Gell","year":"1998","unstructured":"Gell JS, Oh J, Rainey WE, Carr BR (1998) Effect of estradiol on DHEAS production in the human adrenocortical cell line, H295R. J Soc Gynecol Invest 5:144\u2013148","journal-title":"J Soc Gynecol Invest"},{"key":"23_CR8","doi-asserted-by":"publisher","first-page":"579","DOI":"10.1095\/biolreprod.104.027300","volume":"71","author":"CV Rao","year":"2004","unstructured":"Rao CV, Zhou XL, Lei ZM (2004) Functional luteinizing hormone\/chorioninc gonadotropin receptors in human adrenal cortical H295R cells. Biol Reprod 71:579\u2013587","journal-title":"Biol Reprod"},{"key":"23_CR9","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2012\/837901","volume":"2012","author":"J Kaludjerovic","year":"2012","unstructured":"Kaludjerovic J, Ward WE (2012) The interplay between estrogen and fetal adrenal cortex. J Nutr Metab 2012:1\u201312","journal-title":"J Nutr Metab"},{"key":"23_CR10","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1196\/annals.1290.016","volume":"997","author":"G Mastorakos","year":"2003","unstructured":"Mastorakos G, Ilias I (2003) Maternal and fetal hypothalamic-pituitary-adrenal axes during pregnancy and postpartum. Ann N Y Acad Sci 997:136\u2013149","journal-title":"Ann N Y Acad Sci"},{"key":"23_CR11","first-page":"1","volume":"42","author":"V Tsatsaris","year":"2006","unstructured":"Tsatsaris V, Malassin\u00e9 A, Fournier T, Handschuh K, Schaaps J-P, Foidart J-M, Evain-Brion D (2006) Placenta humain. Gyn\u00e9col Obst\u00e9tr 42:1\u201323","journal-title":"Gyn\u00e9col Obst\u00e9tr"},{"key":"23_CR12","doi-asserted-by":"publisher","first-page":"1737","DOI":"10.1210\/en.2004-1124","volume":"146","author":"ED Albrecht","year":"2005","unstructured":"Albrecht ED, Aberdeen GW, Pepe GJ (2005) Estrogen elicits cortical zone-specific effects on development of the primate fetal adrenal gland. Endocrinology 146:1737\u20131744","journal-title":"Endocrinology"},{"key":"23_CR13","doi-asserted-by":"publisher","first-page":"S4","DOI":"10.1016\/j.placenta.2008.11.014","volume":"30","author":"GE Lash","year":"2009","unstructured":"Lash GE, Ansari T, Bischof P, Burton GJ, Chamley L, Crocker I, Dantzer V, Desoye G, Drewlo S, Fazleabas A, Jansson T, Keating S, Kliman HJ, Lang I, Mayhew T, Meiri H, Miller RK, Nelson DM, Pfarrer C, Roberts C, Sammar M, Sharma S, Shiverick K, Strunk D, Turner MA, Huppertz B (2009) IFPA meeting 2008 workshops report. Placenta 30:S4\u2013S14","journal-title":"Placenta"},{"key":"23_CR14","first-page":"2101","volume":"27","author":"U Jeschke","year":"2007","unstructured":"Jeschke U, Richter D-U, M\u00f6bius B-M, Briese V, Myolonas I, Friese K (2007) Stimulation of progesterone, estradiol and cortisol in trophoblast tumor BeWo cells by glycodelin A N-glycans. Anticancer Res 27:2101\u20132108","journal-title":"Anticancer Res"},{"key":"23_CR15","doi-asserted-by":"publisher","first-page":"483","DOI":"10.1016\/j.placenta.2005.04.005","volume":"27","author":"ED Albrecht","year":"2006","unstructured":"Albrecht ED, Bonagura TW, Burleigh DW, Enders AC, Aberdeen GW, Pepe GJ (2006) Suppression of extravillous trophoblast invasion of uterine spiral arteries by estrogen during early baboon pregnancy. Placenta 27:483\u2013490","journal-title":"Placenta"},{"key":"23_CR16","doi-asserted-by":"publisher","first-page":"S63","DOI":"10.1016\/j.placenta.2011.12.001","volume":"33","author":"YP Gambino","year":"2012","unstructured":"Gambino YP, Maymo JL, Perez Perez A, Calvo JC, Sanchez-Margalet V, Varone CL (2012) Elsevier Trophoblast Research Award lecture: molecular mechanisms underlying estrogen functions in trophoblastic cells\u00a0\u2013 focus on leptin expression. Placenta 33:S63\u2013S70","journal-title":"Placenta"},{"key":"23_CR17","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1289\/ehp.10545","volume":"116","author":"MV Olwenn","year":"2008","unstructured":"Olwenn MV, Shialis T, Lester JN, Scrimshaw MD, Boobis AR, Voulvoulis N (2008) Testicular dysgenesis syndrome and the estrogen hypothesis: a quantitative meta-analysis. Environ Health Perspect 116:149\u2013157","journal-title":"Environ Health Perspect"},{"key":"23_CR18","doi-asserted-by":"publisher","first-page":"910","DOI":"10.1002\/bdra.20707","volume":"88","author":"J Toppari","year":"2010","unstructured":"Toppari J, Virtanen HE, Main KM, Skakkebaek NE (2010) Cryptorchidism and hypospadias as a sign of testicular dysgenesis syndrome (TDS): Environmental connection. Birth Defects Res A Clin Mol Teratol 88:910\u2013919","journal-title":"Birth Defects Res A Clin Mol Teratol"},{"key":"23_CR19","doi-asserted-by":"publisher","first-page":"4774","DOI":"10.1210\/en.2014-1221","volume":"155","author":"A Dumitrescu","year":"2014","unstructured":"Dumitrescu A, Aberdeen GW, Pepe GJ, Albrecht ED (2014) Placental estrogen suppresses cyclin D1 expression in the nonhuman primate fetal adrenal cortex. Endocrinology 155:4774\u20134784","journal-title":"Endocrinology"},{"key":"23_CR20","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1210\/jc.2004-0865","volume":"90","author":"R Sirianni","year":"2005","unstructured":"Sirianni R, Rehman KS, Carr BR, Parker CR, Rainey WE (2005) Corticotropin-releasing hormone directly stimulates cortisol and the cortisol biosynthetic pathway in human fetal adrenal cells. J Clin Endocrinol Metabol 90:279\u2013285","journal-title":"J Clin Endocrinol Metabol"},{"key":"23_CR21","doi-asserted-by":"publisher","first-page":"5393","DOI":"10.1210\/jc.2005-0680","volume":"90","author":"R Sirianni","year":"2005","unstructured":"Sirianni R, Mayhew BA, Carr BR, Parker CR, Rainey WE (2005) Corticotropin-releasing hormone (CRH) and urocortin act through type 1 CRH receptors to stimulate dehydroepiandrosterone sulfate production in human fetal adrenal cells. J Clin Endocrinol Metabol 90:5393\u20135400","journal-title":"J Clin Endocrinol Metabol"},{"key":"23_CR22","first-page":"2916","volume":"83","author":"R Smith","year":"1998","unstructured":"Smith R, Mesiano S, Chan E-C, Brown S, Jaffe RB (1998) Corticotropin-releasing hormone directly and preferentially stimulates dehydroepiandrosterone sulfate secretion by human fetal adrenal cortical cells. J Clin Endocrinol Metabol 83:2916\u20132920","journal-title":"J Clin Endocrinol Metabol"},{"key":"23_CR23","doi-asserted-by":"publisher","first-page":"779","DOI":"10.1095\/biolreprod41.5.779","volume":"41","author":"L Riopel","year":"1989","unstructured":"Riopel L, Branchaud CL, Goodyer CG, Zweig M, Lipowski L, Adkar V, Lefebvre Y (1989) Effect of placental factors on growth and function of the human fetal adrenal in vitro. Biol Reprod 41:779\u2013789","journal-title":"Biol Reprod"},{"key":"23_CR24","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1210\/en.2010-0525","volume":"152","author":"C Gennari-Moser","year":"2011","unstructured":"Gennari-Moser C, Khankin EV, Schuller S, Escher G, Frey BM, Portmann CB, Baumann MU, Lehmann AD, Surbek D, Karumanchi SA, Frey FJ, Mohaupt MG (2011) Regulation of placental growth by aldosterone and cortisol. Endocrinology 152:263\u2013271","journal-title":"Endocrinology"},{"key":"23_CR25","doi-asserted-by":"publisher","first-page":"1444","DOI":"10.1210\/me.2011-0026","volume":"25","author":"AI Frolova","year":"2011","unstructured":"Frolova AI, O'Neill K, Moley KH (2011) Dehydroepiandrosterone inhibits glucose flux through the pentose phosphate pathway in human and mouse endometrial stromal cells, preventing decidualization and implantation. Mol Endocrinol 25:1444\u20131455","journal-title":"Mol Endocrinol"}],"container-title":["Methods in Molecular Biology","Preeclampsia"],"original-title":[],"link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/978-1-4939-7498-6_23","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,10,7]],"date-time":"2019-10-07T02:46:51Z","timestamp":1570416411000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/978-1-4939-7498-6_23"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,12,2]]},"ISBN":["9781493974979","9781493974986"],"references-count":25,"URL":"https:\/\/doi.org\/10.1007\/978-1-4939-7498-6_23","relation":{"is-part-of":[{"id-type":"doi","id":"https:\/\/doi.org\/10.1007\/978-1-4939-7498-6","asserted-by":"object"}]},"ISSN":["1064-3745","1940-6029"],"issn-type":[{"value":"1064-3745","type":"print"},{"value":"1940-6029","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,12,2]]}}}