{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T10:06:59Z","timestamp":1792663619433,"version":"4.5.0"},"publisher-location":"New York, NY","reference-count":66,"publisher":"Springer New York","isbn-type":[{"value":"9781493975365","type":"print"},{"value":"9781493975372","type":"electronic"}],"license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018]]},"DOI":"10.1007\/978-1-4939-7537-2_8","type":"book-chapter","created":{"date-parts":[[2018,2,23]],"date-time":"2018-02-23T09:53:40Z","timestamp":1519379620000},"page":"121-140","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Quantitative Peptidomics: General Considerations"],"prefix":"10.1007","author":[{"given":"Lloyd","family":"Fricker","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,2,24]]},"reference":[{"key":"8_CR1","unstructured":"Chard T (1987) In: Burdon RH, Van Knippenberg PH (ed) An introduction to radioimmunoassay and related techniques, Elsevier, Amsterdam, p 1\u2013255"},{"key":"8_CR2","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.jchromb.2003.07.019","volume":"803","author":"G Baggerman","year":"2004","unstructured":"Baggerman G, Verleyen P, Clynen E et al (2004) Peptidomics. J Chromatogr B Analyt Technol Biomed Life Sci 803:3\u201316","journal-title":"J Chromatogr B Analyt Technol Biomed Life Sci"},{"key":"8_CR3","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1002\/mas.20079","volume":"25","author":"LD Fricker","year":"2006","unstructured":"Fricker LD, Lim J, Pan H et al (2006) Peptidomics: identification and quantification of endogenous peptides in neuroendocrine tissues. Mass Spectrom Rev 25:327\u2013344","journal-title":"Mass Spectrom Rev"},{"key":"8_CR4","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.euprot.2014.02.014","volume":"3","author":"M Schrader","year":"2014","unstructured":"Schrader M, Schultz-Knappe P, Fricker LD (2014) Historical perspective of peptidomics. EuPA Open Proteom 3:171\u2013182","journal-title":"EuPA Open Proteom"},{"key":"8_CR5","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1111\/j.1471-4159.2004.02522.x","volume":"90","author":"FY Che","year":"2004","unstructured":"Che FY, Yuan Q, Kalinina E et al (2004) Examination of the rate of peptide biosynthesis in neuroendocrine cell lines using a stable isotopic label and mass spectrometry. J Neurochem 90:585\u2013594","journal-title":"J Neurochem"},{"key":"8_CR6","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1074\/mcp.M200025-MCP200","volume":"1","author":"SE Ong","year":"2002","unstructured":"Ong SE, Blagoev B, Kratchmarova I et al (2002) Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics. Mol Cell Proteomics 1:376\u2013386","journal-title":"Mol Cell Proteomics"},{"key":"8_CR7","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1021\/ac4023378","volume":"86","author":"BR Southey","year":"2014","unstructured":"Southey BR, Lee JE, Zamdborg L et al (2014) Comparing label-free quantitative peptidomics approaches to characterize diurnal variation of peptides in the rat suprachiasmatic nucleus. Anal Chem 86:443\u2013452","journal-title":"Anal Chem"},{"key":"8_CR8","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1111\/j.1471-4159.2010.06760.x","volume":"114","author":"JH Wardman","year":"2010","unstructured":"Wardman JH, Zhang X, Gagnon S et al (2010) Analysis of peptides in prohormone convertase 1\/3 null mouse brain using quantitative peptidomics. J Neurochem 114:215\u2013225","journal-title":"J Neurochem"},{"key":"8_CR9","doi-asserted-by":"crossref","first-page":"1168","DOI":"10.1111\/j.1471-4159.2009.06530.x","volume":"112","author":"X Zhang","year":"2010","unstructured":"Zhang X, Pan H, Peng B et al (2010) Neuropeptidomic analysis establishes a major role for prohormone convertase-2 in neuropeptide biosynthesis. J Neurochem 112:1168\u20131179","journal-title":"J Neurochem"},{"key":"8_CR10","doi-asserted-by":"crossref","first-page":"1596","DOI":"10.1111\/j.1471-4159.2008.05722.x","volume":"107","author":"X Zhang","year":"2008","unstructured":"Zhang X, Che FY, Berezniuk I et al (2008) Peptid\u1e47ns for neuropeptide processing. J Neurochem 107:1596\u20131613","journal-title":"J Neurochem"},{"key":"8_CR11","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1385\/JMN:28:3:265","volume":"28","author":"FY Che","year":"2006","unstructured":"Che FY, Vathy I, Fricker LD (2006) Quantitative peptidomics in mice: effect of cocaine treatment. J Mol Neurosci 28:265\u2013275","journal-title":"J Mol Neurosci"},{"key":"8_CR12","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1385\/JMN:28:3:277","volume":"28","author":"FM Decaillot","year":"2006","unstructured":"Decaillot FM, Che FY, Fricker LD et al (2006) Peptidomics of Cpefat\/fat mouse hypothalamus and striatum: effect of chronic morphine administration. J Mol Neurosci 28:277\u2013284","journal-title":"J Mol Neurosci"},{"key":"8_CR13","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1111\/j.1471-4159.2005.03614.x","volume":"96","author":"J Lim","year":"2006","unstructured":"Lim J, Berezniuk I, Che FY et al (2006) Altered neuropeptide processing in prefrontal cortex of Cpefat\/fat mice: implications for neuropeptide discovery. J Neurochem 96:1169\u20131181","journal-title":"J Neurochem"},{"key":"8_CR14","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1007\/s00216-012-6203-4","volume":"404","author":"M Bantscheff","year":"2012","unstructured":"Bantscheff M, Lemeer S, Savitski MM et al (2012) Quantitative mass spectrometry in proteomics: critical review update from 2007 to the present. Anal Bioanal Chem 404:939\u2013965","journal-title":"Anal Bioanal Chem"},{"key":"8_CR15","doi-asserted-by":"crossref","first-page":"2526","DOI":"10.1016\/j.jprot.2012.01.028","volume":"75","author":"V Ranc","year":"2012","unstructured":"Ranc V, Petruzziello F, Kretz R et al (2012) Broad characterization of endogenous peptides in the tree shrew visual system. J Proteomics 75:2526\u20132535","journal-title":"J Proteomics"},{"key":"8_CR16","doi-asserted-by":"crossref","first-page":"1487","DOI":"10.1074\/mcp.M500084-MCP200","volume":"4","author":"WM Old","year":"2005","unstructured":"Old WM, Meyer-Arendt K, Aveline-Wolf L et al (2005) Comparison of label-free methods for quantifying human proteins by shotgun proteomics. Mol Cell Proteomics 4:1487\u20131502","journal-title":"Mol Cell Proteomics"},{"key":"8_CR17","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1002\/1615-9861(200101)1:1<79::AID-PROT79>3.0.CO;2-8","volume":"1","author":"EJ Bures","year":"2001","unstructured":"Bures EJ, Courchesne PL, Douglass J et\u00a0al (2001) Identification of incompletely processed potential carboxypeptidase E substrates from CpEfat\/CpEfat mice. Proteomics 1:79\u201392","journal-title":"Proteomics"},{"key":"8_CR18","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1016\/j.cell.2016.06.041","volume":"166","author":"U Kusebauch","year":"2016","unstructured":"Kusebauch U, Campbell DS, Deutsch EW et al (2016) Human SRMAtlas: a resource of targeted assays to quantify the complete human proteome. Cell 166:766\u2013778","journal-title":"Cell"},{"key":"8_CR19","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1038\/nature11835","volume":"494","author":"P Picotti","year":"2013","unstructured":"Picotti P, Clement-Ziza M, Lam H et al (2013) A complete mass-spectrometric map of the yeast proteome applied to quantitative trait analysis. Nature 494:266\u2013270","journal-title":"Nature"},{"key":"8_CR20","first-page":"107","volume-title":"Colloquium series on neuropeptides","author":"LD Fricker","year":"2012","unstructured":"Fricker LD (2012) Neuropeptides and other bioactive peptides. In: Fricker LD, Devi L (eds) Colloquium series on neuropeptides. Morgan & Claypool Life Sciences, Charleston, SC, p 107"},{"key":"8_CR21","doi-asserted-by":"crossref","first-page":"9298","DOI":"10.1021\/ac801654h","volume":"80","author":"C Morano","year":"2008","unstructured":"Morano C, Zhang X, Fricker LD (2008) Multiple isotopic labels for quantitative mass spectrometry. Anal Chem 80:9298\u20139309","journal-title":"Anal Chem"},{"key":"8_CR22","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1002\/jms.743","volume":"40","author":"FY Che","year":"2005","unstructured":"Che FY, Fricker LD (2005) Quantitative peptidomics of mouse pituitary: comparison of different stable isotopic tags. J Mass Spectrom 40:238\u2013249","journal-title":"J Mass Spectrom"},{"key":"8_CR23","doi-asserted-by":"crossref","first-page":"3190","DOI":"10.1021\/ac015681a","volume":"74","author":"FY Che","year":"2002","unstructured":"Che FY, Fricker LD (2002) Quantitation of neuropeptides in Cpe fat\/Cpe fat mice using differential isotopic tags and mass spectrometry. Anal Chem 74:3190\u20133198","journal-title":"Anal Chem"},{"key":"8_CR24","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1007\/978-1-4939-3524-6_11","volume":"1410","author":"T Greer","year":"2016","unstructured":"Greer T, Li L (2016) Isotopic N,N-dimethyl leucine (iDiLeu) for absolute quantification of peptides using a standard curve approach. Methods Mol Biol 1410:195\u2013206","journal-title":"Methods Mol Biol"},{"key":"8_CR25","doi-asserted-by":"crossref","first-page":"4463","DOI":"10.1016\/j.chroma.2010.02.084","volume":"1217","author":"J Wang","year":"2010","unstructured":"Wang J, Zhang Y, Xiang F et al (2010) Combining capillary electrophoresis matrix-assisted laser desorption\/ionization mass spectrometry and stable isotopic labeling techniques for comparative crustacean peptidomics. J Chromatogr A 1217:4463\u20134470","journal-title":"J Chromatogr A"},{"key":"8_CR26","doi-asserted-by":"crossref","first-page":"2817","DOI":"10.1021\/ac902778d","volume":"82","author":"F Xiang","year":"2010","unstructured":"Xiang F, Ye H, Chen RB et al (2010) N,N-dimethyl leucines as novel isobaric tandem mass tags for quantitative proteomics and peptidomics. Anal Chem 82:2817\u20132825","journal-title":"Anal Chem"},{"key":"8_CR27","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1159\/000456282","volume":"41","author":"L Wu","year":"2017","unstructured":"Wu L, Li H, Li X et al (2017) Peptidomic analysis of cultured cardiomyocytes exposed to acute ischemic-hypoxia. Cell Physiol Biochem 41:358\u2013368","journal-title":"Cell Physiol Biochem"},{"key":"8_CR28","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1038\/13690","volume":"17","author":"SP Gygi","year":"1999","unstructured":"Gygi SP, Rist B, Gerber SA et al (1999) Quantitative analysis of complex protein mixtures using isotope-coded affinity tags. Nat Biotechnol 17:994\u2013999","journal-title":"Nat Biotechnol"},{"key":"8_CR29","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.1039\/c003317k","volume":"6","author":"LD Fricker","year":"2010","unstructured":"Fricker LD (2010) Analysis of mouse brain peptides using mass spectrometry-based peptidomics: implications for novel functions ranging from non-classical neuropeptides to microproteins. Mol Biosyst 6:1355\u20131365","journal-title":"Mol Biosyst"},{"key":"8_CR30","doi-asserted-by":"crossref","first-page":"1763","DOI":"10.1111\/j.1471-4159.2006.04067.x","volume":"98","author":"H Pan","year":"2006","unstructured":"Pan H, Che FY, Peng B et al (2006) The role of prohormone convertase-2 in hypothalamic neuropeptide processing: a quantitative neuropeptidomic study. J Neurochem 98:1763\u20131777","journal-title":"J Neurochem"},{"key":"8_CR31","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1002\/jms.742","volume":"40","author":"FY Che","year":"2005","unstructured":"Che FY, Biswas R, Fricker LD (2005) Relative quantitation of peptides in wild type and Cpefat\/fat mouse pituitary using stable isotopic tags and mass spectrometry. J Mass Spectrom 40:227\u2013237","journal-title":"J Mass Spectrom"},{"key":"8_CR32","doi-asserted-by":"crossref","first-page":"4451","DOI":"10.1074\/jbc.M411178200","volume":"280","author":"FY Che","year":"2005","unstructured":"Che FY, Yuan Q, Kalinina E et al (2005) Peptidomics of Cpe fat\/fat mouse hypothalamus: effect of food deprivation and exercise on peptide levels. J Biol Chem 280:4451\u20134461","journal-title":"J Biol Chem"},{"key":"8_CR33","doi-asserted-by":"crossref","first-page":"ra43","DOI":"10.1126\/scisignal.aad0694","volume":"9","author":"I Gomes","year":"2016","unstructured":"Gomes I, Bobeck EN, Margolis EB et al (2016) Identification of GPR83 as the receptor for the neuroendocrine peptide PEN. Sci Signal 9:ra43","journal-title":"Sci Signal"},{"key":"8_CR34","doi-asserted-by":"crossref","first-page":"38234","DOI":"10.1074\/jbc.M110.158626","volume":"285","author":"PJ Lyons","year":"2010","unstructured":"Lyons PJ, Fricker LD (2010) Substrate specificity of human carboxypeptidase A6. J Biol Chem 285:38234\u201338242","journal-title":"J Biol Chem"},{"key":"8_CR35","doi-asserted-by":"crossref","first-page":"18385","DOI":"10.1074\/jbc.M109.060350","volume":"285","author":"S Tanco","year":"2010","unstructured":"Tanco S, Zhang X, Morano C et al (2010) Human carboxypeptidase A4: characterization of the substrate specificity and implications for a role in extracellular peptide processing. J Biol Chem 285:18385\u201318396","journal-title":"J Biol Chem"},{"key":"8_CR36","doi-asserted-by":"crossref","first-page":"14105","DOI":"10.1074\/jbc.M807916200","volume":"284","author":"DA Berti","year":"2009","unstructured":"Berti DA, Morano C, Russo LC et al (2009) Analysis of intracellular substrates and products of thimet oligopeptidase (EC 3.4.24.15) in human embryonic kidney 293 cells. J Biol Chem 284:14105\u201314116","journal-title":"J Biol Chem"},{"key":"8_CR37","doi-asserted-by":"crossref","first-page":"4667","DOI":"10.1021\/pr060690r","volume":"6","author":"FY Che","year":"2007","unstructured":"Che FY, Zhang X, Berezniuk I et al (2007) Optimization of neuropeptide extraction from the mouse hypothalamus. J Proteome Res 6:4667\u20134676","journal-title":"J Proteome Res"},{"key":"8_CR38","volume":"11","author":"S Dasgupta","year":"2016","unstructured":"Dasgupta S, Yang C, Castro LM et al (2016) Analysis of the yeast peptidome and comparison with the human peptidome. PLoS One 11:e0163312","journal-title":"PLoS One"},{"key":"8_CR39","volume":"10","author":"S Dasgupta","year":"2015","unstructured":"Dasgupta S, Fishman MA, Mahallati H et al (2015) Reduced levels of proteasome products in a mouse striatal cell model of Huntington\u2019s disease. PLoS One 10:e0145333","journal-title":"PLoS One"},{"key":"8_CR40","volume":"9","author":"S Dasgupta","year":"2014","unstructured":"Dasgupta S, Castro LM, Dulman R et al (2014) Proteasome inhibitors alter levels of intracellular peptides in HEK293T and SH-SY5Y cells. PLoS One 9:e103604","journal-title":"PLoS One"},{"key":"8_CR41","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0060981","volume":"8","author":"I Berezniuk","year":"2013","unstructured":"Berezniuk I, Sironi JJ, Wardman J et\u00a0al (2013) Quantitative peptidomics of Purkinje cell degeneration mice. PLoS One 8:e60981","journal-title":"PLoS One"},{"key":"8_CR42","doi-asserted-by":"crossref","first-page":"2408","DOI":"10.1016\/j.bbapap.2013.01.043","volume":"1834","author":"JS Gelman","year":"2013","unstructured":"Gelman JS, Dasgupta S, Berezniuk I et al (2013) Analysis of peptides secreted from cultured mouse brain tissue. Biochim Biophys Acta 1834:2408\u20132417","journal-title":"Biochim Biophys Acta"},{"key":"8_CR43","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0053263","volume":"8","author":"JS Gelman","year":"2013","unstructured":"Gelman JS, Sironi J, Berezniuk I et al (2013) Alterations of the intracellular peptidome in response to the proteasome inhibitor bortezomib. PLoS One 8:e53263","journal-title":"PLoS One"},{"key":"8_CR44","doi-asserted-by":"crossref","first-page":"1981","DOI":"10.1021\/pr2012076","volume":"11","author":"LD Fricker","year":"2012","unstructured":"Fricker LD, Gelman JS, Castro LM et al (2012) Peptidomic analysis of HEK293T cells: effect of the proteasome inhibitor epoxomicin on intracellular peptides. J Proteome Res 11:1981\u20131990","journal-title":"J Proteome Res"},{"key":"8_CR45","doi-asserted-by":"crossref","first-page":"1583","DOI":"10.1021\/pr100952f","volume":"10","author":"JS Gelman","year":"2011","unstructured":"Gelman JS, Sironi J, Castro LM et al (2011) Peptidomic analysis of human cell lines. J Proteome Res 10:1583\u20131592","journal-title":"J Proteome Res"},{"key":"8_CR46","doi-asserted-by":"crossref","first-page":"1813","DOI":"10.1096\/fj.09-147942","volume":"24","author":"I Berezniuk","year":"2010","unstructured":"Berezniuk I, Sironi J, Callaway MB et al (2010) CCP1\/Nna1 functions in protein turnover in mouse brain: implications for cell death in Purkinje cell degeneration mice. FASEB J 24:1813\u20131823","journal-title":"FASEB J"},{"key":"8_CR47","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1111\/j.1471-4159.2010.06653.x","volume":"113","author":"JS Gelman","year":"2010","unstructured":"Gelman JS, Sironi J, Castro LM et al (2010) Hemopressins and other hemoglobin-derived peptides in mouse brain: comparison between brain, blood, and heart peptidome and regulation in Cpefat\/fat mice. J Neurochem 113:871\u2013880","journal-title":"J Neurochem"},{"key":"8_CR48","doi-asserted-by":"crossref","first-page":"3662","DOI":"10.1021\/ac025614w","volume":"74","author":"R Zhang","year":"2002","unstructured":"Zhang R, Sioma CS, Thompson RA et al (2002) Controlling deuterium isotope effects in comparative proteomics. Anal Chem 74:3662\u20133669","journal-title":"Anal Chem"},{"key":"8_CR49","doi-asserted-by":"crossref","first-page":"1981","DOI":"10.1007\/s13361-015-1231-x","volume":"26","author":"LD Fricker","year":"2015","unstructured":"Fricker LD (2015) Limitations of mass spectrometry-based peptidomic approaches. J Am Soc Mass Spectrom 26:1981\u20131991","journal-title":"J Am Soc Mass Spectrom"},{"key":"8_CR50","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1038\/nprot.2009.21","volume":"4","author":"PJ Boersema","year":"2009","unstructured":"Boersema PJ, Raijmakers R, Lemeer S et al (2009) Multiplex peptide stable isotope dimethyl labeling for quantitative proteomics. Nat Protoc 4:484\u2013494","journal-title":"Nat Protoc"},{"key":"8_CR51","doi-asserted-by":"publisher","unstructured":"Tolonen AC, Haas W (2014) Quantitative proteomics using reductive dimethylation for stable isotope labeling. J Vis Exp. https:\/\/doi.org\/10.3791\/51416","DOI":"10.3791\/51416"},{"key":"8_CR52","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.1074\/mcp.M400129-MCP200","volume":"3","author":"PL Ross","year":"2004","unstructured":"Ross PL, Huang YN, Marchese JN et al (2004) Multiplexed protein quantitation in Saccharomyces cerevisiae using amine-reactive isobaric tagging reagents. Mol Cell Proteomics 3:1154\u20131169","journal-title":"Mol Cell Proteomics"},{"key":"8_CR53","doi-asserted-by":"crossref","first-page":"2921","DOI":"10.1021\/ac702422x","volume":"80","author":"L Dayon","year":"2008","unstructured":"Dayon L, Hainard A, Licker V et al (2008) Relative quantification of proteins in human cerebrospinal fluids by MS\/MS using 6-plex isobaric tags. Anal Chem 80:2921\u20132931","journal-title":"Anal Chem"},{"issue":"6","key":"8_CR54","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1089\/dna.2017.3647","volume":"36","author":"J Zhang","year":"2017","unstructured":"Zhang J, Liang D, Cheng Q et al (2017) Peptidomic analysis of fetal heart tissue for identification of endogenous peptides involved in tetralogy of fallot. DNA Cell Biol 36(6):451\u2013461","journal-title":"DNA Cell Biol"},{"key":"8_CR55","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1002\/rcm.7201","volume":"29","author":"DC Frost","year":"2015","unstructured":"Frost DC, Greer T, Xiang F et al (2015) Development and characterization of novel 8-plex DiLeu isobaric labels for quantitative proteomics and peptidomics. Rapid Commun Mass Spectrom 29:1115\u20131124","journal-title":"Rapid Commun Mass Spectrom"},{"key":"8_CR56","doi-asserted-by":"crossref","first-page":"1646","DOI":"10.1021\/ac503276z","volume":"87","author":"DC Frost","year":"2015","unstructured":"Frost DC, Greer T, Li L (2015) High-resolution enabled 12-plex DiLeu isobaric tags for quantitative proteomics. Anal Chem 87:1646\u20131654","journal-title":"Anal Chem"},{"key":"8_CR57","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1007\/s13361-014-1012-y","volume":"26","author":"T Greer","year":"2015","unstructured":"Greer T, Lietz CB, Xiang F et al (2015) Novel isotopic N,N-dimethyl leucine (iDiLeu) reagents enable absolute quantification of peptides and proteins using a standard curve approach. J Am Soc Mass Spectrom 26:107\u2013119","journal-title":"J Am Soc Mass Spectrom"},{"key":"8_CR58","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/j.peptides.2012.05.007","volume":"36","author":"L Hui","year":"2012","unstructured":"Hui L, Xiang F, Zhang Y et al (2012) Mass spectrometric elucidation of the neuropeptidome of a crustacean neuroendocrine organ. Peptides 36:230\u2013239","journal-title":"Peptides"},{"key":"8_CR59","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1002\/rcm.6875","volume":"28","author":"RM Sturm","year":"2014","unstructured":"Sturm RM, Lietz CB, Li L (2014) Improved isobaric tandem mass tag quantification by ion mobility mass spectrometry. Rapid Commun Mass Spectrom 28:1051\u20131060","journal-title":"Rapid Commun Mass Spectrom"},{"key":"8_CR60","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0135415","volume":"10","author":"T Greer","year":"2015","unstructured":"Greer T, Hao L, Nechyporenko A et al (2015) Custom 4-plex DiLeu Isobaric labels enable relative quantification of urinary proteins in men with lower urinary tract symptoms (LUTS). PLoS One 10:e0135415","journal-title":"PLoS One"},{"key":"8_CR61","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1007\/978-1-61779-885-6_29","volume":"893","author":"S Lemeer","year":"2012","unstructured":"Lemeer S, Hahne H, Pachl F et al (2012) Software tools for MS-based quantitative proteomics: a brief overview. Methods Mol Biol 893:489\u2013499","journal-title":"Methods Mol Biol"},{"key":"8_CR62","doi-asserted-by":"crossref","first-page":"4185","DOI":"10.1210\/en.2007-0123","volume":"148","author":"LD Fricker","year":"2007","unstructured":"Fricker LD (2007) Neuropeptidomics to study peptide processing in animal models of obesity. Endocrinology 148:4185\u20134190","journal-title":"Endocrinology"},{"key":"8_CR63","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M113.497917","volume-title":"J Biol Chem","author":"I Berezniuk","year":"2013","unstructured":"Berezniuk I, Lyons PJ, Sironi JJ et al (2013) Cytosolic carboxypeptidase 5 removes alpha- and gamma-linked glutamates from tubulin. In: J Biol Chem. https:\/\/doi.org\/10.1074\/jbc.M113.497917"},{"key":"8_CR64","doi-asserted-by":"crossref","first-page":"6503","DOI":"10.1074\/jbc.M111.309138","volume":"287","author":"I Berezniuk","year":"2012","unstructured":"Berezniuk I, Vu HT, Lyons PJ et al (2012) Cytosolic carboxypeptidase 1 is involved in processing alpha- and beta-tubulin. J Biol Chem 287:6503\u20136517","journal-title":"J Biol Chem"},{"key":"8_CR65","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1007\/978-1-61779-204-5_17","volume":"768","author":"J Wardman","year":"2011","unstructured":"Wardman J, Fricker LD (2011) Quantitative peptidomics of mice lacking peptide-processing enzymes. Methods Mol Biol 768:307\u2013323","journal-title":"Methods Mol Biol"},{"key":"8_CR66","doi-asserted-by":"crossref","first-page":"9971","DOI":"10.1073\/pnas.161542198","volume":"98","author":"FY Che","year":"2001","unstructured":"Che FY, Yan L, Li H et al (2001) Identification of peptides from brain and pituitary of Cpe fat\/Cpe fat mice. Proc Natl Acad Sci U S A 98:9971\u20139976","journal-title":"Proc Natl Acad Sci U S A"}],"container-title":["Methods in Molecular Biology","Peptidomics"],"original-title":[],"link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/978-1-4939-7537-2_8","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T13:48:30Z","timestamp":1719841710000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/978-1-4939-7537-2_8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018]]},"ISBN":["9781493975365","9781493975372"],"references-count":66,"URL":"https:\/\/doi.org\/10.1007\/978-1-4939-7537-2_8","relation":{},"ISSN":["1064-3745","1940-6029"],"issn-type":[{"value":"1064-3745","type":"print"},{"value":"1940-6029","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018]]}}}