{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T03:50:37Z","timestamp":1785815437572,"version":"3.56.0"},"publisher-location":"New York, NY","reference-count":19,"publisher":"Springer New York","isbn-type":[{"value":"9781493975709","type":"print"},{"value":"9781493975716","type":"electronic"}],"license":[{"start":{"date-parts":[[2017,12,9]],"date-time":"2017-12-09T00:00:00Z","timestamp":1512777600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018]]},"DOI":"10.1007\/978-1-4939-7571-6_28","type":"book-chapter","created":{"date-parts":[[2017,12,8]],"date-time":"2017-12-08T10:59:42Z","timestamp":1512730782000},"page":"373-378","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Spared Nerve Injury as a Long-Lasting Model of Neuropathic Pain"],"prefix":"10.1007","author":[{"given":"Serena","family":"Boccella","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Guida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enza","family":"Palazzo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ida","family":"Marabese","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vito","family":"de Novellis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabatino","family":"Maione","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Livio","family":"Luongo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,12,9]]},"reference":[{"key":"28_CR1","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/0304-3959(88)90209-6","volume":"33","author":"GJ Bennett","year":"1988","unstructured":"Bennett GJ, Xie YK (1988) A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man. Pain 33:87\u2013107","journal-title":"Pain"},{"key":"28_CR2","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/0304-3959(90)91074-S","volume":"43","author":"Z Seltzer","year":"1990","unstructured":"Seltzer Z, Dubner R, Shir Y (1990) A novel behavioral model of neuropathic pain disorders produced in rats by partial sciatic nerve injury. Pain 43:205\u2013218","journal-title":"Pain"},{"key":"28_CR3","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/0304-3959(92)90041-9","volume":"50","author":"SH Kim","year":"1992","unstructured":"Kim SH, Chung JM (1992) An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat. Pain 50:355\u2013363","journal-title":"Pain"},{"key":"28_CR4","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.neulet.2017.04.041","volume":"651","author":"A D\u2019Aniello","year":"2017","unstructured":"D\u2019Aniello A, Luongo L, Romano R et al (2017) d-Aspartic acid ameliorates painful and neuropsychiatric changes and reduces \u03b2-amyloid A\u03b2(1-42) peptide in a long lasting model of neuropathic pain. Neurosci Lett 651:151\u2013158","journal-title":"Neurosci Lett"},{"key":"28_CR5","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/S0304-3959(00)00276-1","volume":"87","author":"I Decosterd","year":"2000","unstructured":"Decosterd I, Woolf CJ (2000) Spared nerve injury: an animal model of persistent peripheral neuropathic pain. Pain 87:149\u2013158","journal-title":"Pain"},{"key":"28_CR6","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1067\/S1526-5900(03)00781-8","volume":"4","author":"SD Shields","year":"2003","unstructured":"Shields SD, Eckert WA 3rd, Basbaum AI (2003) Spared nerve injury model of neuropathic pain in the mouse: a behavioral and anatomic analysis. J Pain 4:465\u2013470","journal-title":"J Pain"},{"key":"28_CR7","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.phrs.2014.11.004","volume":"91","author":"F Guida","year":"2015","unstructured":"Guida F, Lattanzi R, Boccella S et al (2015) PC1, a non-peptide PKR1-preferring antagonist, reduces pain behavior and spinal neuronal sensitization in neuropathic mice. Pharmacol Res 91:36\u201346","journal-title":"Pharmacol Res"},{"key":"28_CR8","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.neuropharm.2015.06.003","volume":"97","author":"C Sagheddu","year":"2015","unstructured":"Sagheddu C, Aroni S, De Felice M et al (2015) Enhanced serotonin and mesolimbic dopamine transmissions in a rat model of neuropathic pain. Neuropharmacology 97:383\u2013393","journal-title":"Neuropharmacology"},{"key":"28_CR9","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1186\/s13041-015-0139-5","volume":"8","author":"F Guida","year":"2015","unstructured":"Guida F, Luongo L, Marmo F et al (2015) Palmitoylethanolamide reduces pain-related behaviors and restores glutamatergic synapses homeostasis in the medial prefrontal cortex of neuropathic mice. Mol Brain 8:47. https:\/\/doi.org\/10.1186\/s13041-015-0139-5","journal-title":"Mol Brain"},{"key":"28_CR10","doi-asserted-by":"crossref","first-page":"2196","DOI":"10.1152\/jn.00212.2013","volume":"111","author":"F Rossi","year":"2014","unstructured":"Rossi F, Marabese I, De Chiaro M et al (2014) Dorsal striatum metabotropic glutamate receptor 8 affects nocifensive responses and rostral ventromedial medulla cell activity in neuropathic pain conditions. J Neurophysiol 111:2196\u20132209","journal-title":"J Neurophysiol"},{"key":"28_CR11","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1186\/1744-8069-7-7","volume":"7","author":"V Novellis de","year":"2011","unstructured":"de Novellis V, Vita D, Gatta L et al (2011) The blockade of the transient receptor potential vanilloid type 1 and fatty acid amide hydrolase decreases symptoms and central sequelae in the medial prefrontal cortex of neuropathic rats. Mol Pain 7:7. https:\/\/doi.org\/10.1186\/1744-8069-7-7","journal-title":"Mol Pain"},{"key":"28_CR12","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.nbd.2009.09.021","volume":"37","author":"L Luongo","year":"2010","unstructured":"Luongo L, Palazzo E, Tambaro S et al (2010) 1-(2\u2032,4\u2032-dichlorophenyl)-6-methyl-N-cyclohexylamine-1,4- ihydroindeno[1,2-c]pyraz ole-3-carboxamide, a novel CB2 agonist, alleviates neuropathic pain through functional microglial changes in mice. Neurobiol Dis 37:177\u2013185","journal-title":"Neurobiol Dis"},{"key":"28_CR13","doi-asserted-by":"crossref","first-page":"13712","DOI":"10.3390\/molecules171213712","volume":"17","author":"L Luongo","year":"2012","unstructured":"Luongo L, Petrelli R, Gatta L et al (2012) 5\u2032-Chloro-5\u2032-deoxy-(\u00b1)-ENBA, a potent and selective adenosine A(1) receptor agonist, alleviates neuropathic pain in mice through functional glial and microglial changes without affecting motor or cardiovascular functions. Molecules 17:13712\u201313726","journal-title":"Molecules"},{"key":"28_CR14","doi-asserted-by":"crossref","first-page":"2495","DOI":"10.1093\/cercor\/bhr328","volume":"22","author":"C Giordano","year":"2012","unstructured":"Giordano C, Cristino L, Luongo L et al (2012) TRPV1-dependent and independent alterations in the limbic cortex of neuropathic mice: impact on glial caspases and pain perception. Cereb Cortex 22:2495\u20132518","journal-title":"Cereb Cortex"},{"key":"28_CR15","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1097\/j.pain.0000000000000150","volume":"156","author":"E Palazzo","year":"2015","unstructured":"Palazzo E, Romano R, Luongo L et al (2015) MMPIP, an mGluR7-selective negative allosteric modulator, alleviates pain and normalizes affective and cognitive behavior in neuropathic mice. Pain 156:1060\u20131073","journal-title":"Pain"},{"key":"28_CR16","doi-asserted-by":"crossref","first-page":"1553","DOI":"10.1007\/s00726-016-2205-4","volume":"48","author":"E Palazzo","year":"2016","unstructured":"Palazzo E, Luongo L, Guida F et al (2016) D-Aspartate drinking solution alleviates pain and cognitive impairment in neuropathic mice. Amino Acids 48:1553\u20131567","journal-title":"Amino Acids"},{"key":"28_CR17","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1186\/1744-8069-10-26","volume":"10","author":"RP Bonin","year":"2014","unstructured":"Bonin RP, Bories C, De Koninck Y (2014) A simplified up-down method (SUDO) for measuring mechanical nociception in rodents using von Frey filaments. Mol Pain 10:26. https:\/\/doi.org\/10.1186\/1744-8069-10-26","journal-title":"Mol Pain"},{"key":"28_CR18","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/0165-0270(94)90144-9","volume":"53","author":"SR Chaplan","year":"1994","unstructured":"Chaplan SR, Bach FW, Pogrel JW et al (1994) Quantitative assessment of tactile allodynia in the rat paw. J Neurosci Methods 53:55\u201363","journal-title":"J Neurosci Methods"},{"key":"28_CR19","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/0304-3959(88)90026-7","volume":"32","author":"K Hargreaves","year":"1988","unstructured":"Hargreaves K, Dubner R, Brown F et al (1988) A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia. Pain 32:77\u201388","journal-title":"Pain"}],"container-title":["Methods in Molecular Biology","Neurotrophic Factors"],"original-title":[],"link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/978-1-4939-7571-6_28","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,10]],"date-time":"2022-08-10T02:17:22Z","timestamp":1660097842000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/978-1-4939-7571-6_28"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,12,9]]},"ISBN":["9781493975709","9781493975716"],"references-count":19,"URL":"https:\/\/doi.org\/10.1007\/978-1-4939-7571-6_28","relation":{},"ISSN":["1064-3745","1940-6029"],"issn-type":[{"value":"1064-3745","type":"print"},{"value":"1940-6029","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,12,9]]}}}