{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,13]],"date-time":"2026-11-13T10:54:53Z","timestamp":1794567293036,"version":"4.9.1"},"publisher-location":"New York, NY","reference-count":14,"publisher":"Springer New York","isbn-type":[{"value":"9781493978243","type":"print"},{"value":"9781493978250","type":"electronic"}],"license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018]]},"DOI":"10.1007\/978-1-4939-7825-0_1","type":"book-chapter","created":{"date-parts":[[2018,5,31]],"date-time":"2018-05-31T08:44:16Z","timestamp":1527756256000},"page":"1-16","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Stereological Methods to Quantify Cell Loss in the Huntington\u2019s Disease Human Brain"],"prefix":"10.1007","author":[{"given":"Nasim F.","family":"Mehrabi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Malvindar K.","family":"Singh-Bains","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henry J.","family":"Waldvogel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard L. M.","family":"Faull","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,6,1]]},"reference":[{"key":"1_CR1","doi-asserted-by":"publisher","first-page":"1094","DOI":"10.1093\/brain\/awq047","volume":"133","author":"DC Thu","year":"2010","unstructured":"Thu DC, Oorschot DE, Tippett LJ et al (2010) Cell loss in the motor and cingulate cortex correlates with symptomatology in Huntington\u2019s disease. Brain 133:1094\u20131110","journal-title":"Brain"},{"key":"1_CR2","doi-asserted-by":"publisher","first-page":"717","DOI":"10.1002\/ana.24162","volume":"75","author":"EH Kim","year":"2014","unstructured":"Kim EH, Thu DC, Tippett LJ et al (2014) Cortical interneuron loss and symptom heterogeneity in Huntington disease. Ann Neurol 75:717\u2013727","journal-title":"Ann Neurol"},{"key":"1_CR3","doi-asserted-by":"crossref","first-page":"45","DOI":"10.3233\/JHD-140092","volume":"3","author":"AL Nana","year":"2014","unstructured":"Nana AL, Kim EH, Thu DC et al (2014) Widespread heterogeneous neuronal loss across the cerebral cortex in Huntington's disease. J Huntingtons Dis 3:45\u201364","journal-title":"J Huntingtons Dis"},{"key":"1_CR4","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1016\/j.nbd.2016.08.015","volume":"96","author":"NF Mehrabi","year":"2016","unstructured":"Mehrabi NF, Waldvogel HJ, Tippett LJ et al (2016) Symptom heterogeneity in Huntington\u2019s disease correlates with neuronal degeneration in the cerebral cortex. Neurobiol Dis 96:67\u201374","journal-title":"Neurobiol Dis"},{"key":"1_CR5","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1002\/ana.24694","volume":"80","author":"MK Singh-Bains","year":"2016","unstructured":"Singh-Bains MK, Tippett LJ, Hogg VM et al (2016) Globus pallidus degeneration and clinico-pathological features of Huntington\u2019s disease. Ann Neurol 80:185\u2013201","journal-title":"Ann Neurol"},{"key":"1_CR6","doi-asserted-by":"publisher","first-page":"813","DOI":"10.1016\/j.neuroscience.2004.08.050","volume":"130","author":"C Schmitz","year":"2005","unstructured":"Schmitz C, Hof P (2005) Design-based stereology in neuroscience. Neuroscience 130:813\u2013831","journal-title":"Neuroscience"},{"key":"1_CR7","volume-title":"Geometria degli indivisibili di Bonaventura Cavalieri","author":"B Cavalieri","year":"1966","unstructured":"Cavalieri B, Lombardo-Radice L (1966) Geometria degli indivisibili di Bonaventura Cavalieri, vol 5. Unione Tipografico-Editrice Torinese, Torino"},{"key":"1_CR8","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1111\/j.1365-2818.1987.tb02837.x","volume":"147","author":"H Gundersen","year":"1987","unstructured":"Gundersen H, Jensen E (1987) The efficiency of systematic sampling in stereology and its prediction. J Microsc 147:229\u2013263","journal-title":"J Microsc"},{"key":"1_CR9","doi-asserted-by":"publisher","first-page":"2719","DOI":"10.1038\/nprot.2006.354","volume":"1","author":"HJ Waldvogel","year":"2006","unstructured":"Waldvogel HJ, Curtis MA, Baer K et al (2006) Immunohistochemical staining of post-mortem adult human brain sections. Nat Protoc 1:2719\u20132732","journal-title":"Nat Protoc"},{"key":"1_CR10","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1002\/cne.902960102","volume":"296","author":"MJ West","year":"1990","unstructured":"West MJ, Gundersen H (1990) Unbiased stereological estimation of the number of neurons in the human hippocampus. J Comp Neurol 296:1\u201322","journal-title":"J Comp Neurol"},{"key":"1_CR11","doi-asserted-by":"publisher","first-page":"757","DOI":"10.1016\/j.neuroscience.2005.06.086","volume":"136","author":"L Slomianka","year":"2005","unstructured":"Slomianka L, West MJ (2005) Estimators of the precision of stereological estimates: an example based on the CA1 pyramidal cell layer of rats. Neuroscience 136:757\u2013767","journal-title":"Neuroscience"},{"key":"1_CR12","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1016\/S0166-2236(98)01362-9","volume":"22","author":"MJ West","year":"1999","unstructured":"West MJ (1999) Stereological methods for estimating the total number of neurons and synapses: issues of precision and bias. Trends Neurosci 22:51\u201361","journal-title":"Trends Neurosci"},{"key":"1_CR13","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1046\/j.1365-2818.1999.00555.x","volume":"196","author":"B Andersen","year":"1999","unstructured":"Andersen B, Gundersen H (1999) Pronounced loss of cell nuclei and anisotropic deformation of thick sections. J Microsc 196:69\u201373","journal-title":"J Microsc"},{"key":"1_CR14","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1046\/j.1365-2818.1999.00457.x","volume":"193","author":"HJG Gundersen","year":"1999","unstructured":"Gundersen HJG, Jensen EBV, Kieu K, Nielsen J (1999) The efficiency of systematic sampling in stereology\u2014reconsidered. J Microsc 193:199\u2013211","journal-title":"J Microsc"}],"container-title":["Methods in Molecular Biology","Huntington\u2019s Disease"],"original-title":[],"link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/978-1-4939-7825-0_1","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,11,2]],"date-time":"2020-11-02T17:50:45Z","timestamp":1604339445000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/978-1-4939-7825-0_1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018]]},"ISBN":["9781493978243","9781493978250"],"references-count":14,"URL":"https:\/\/doi.org\/10.1007\/978-1-4939-7825-0_1","relation":{"is-part-of":[{"id-type":"doi","id":"https:\/\/doi.org\/10.1007\/978-1-4939-7825-0","asserted-by":"object"}]},"ISSN":["1064-3745","1940-6029"],"issn-type":[{"value":"1064-3745","type":"print"},{"value":"1940-6029","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018]]}}}