{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,25]],"date-time":"2025-03-25T14:36:38Z","timestamp":1742913398588,"version":"3.40.3"},"publisher-location":"New York, NY","reference-count":57,"publisher":"Springer New York","isbn-type":[{"type":"print","value":"9781493978274"},{"type":"electronic","value":"9781493978281"}],"license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018]]},"DOI":"10.1007\/978-1-4939-7828-1_10","type":"book-chapter","created":{"date-parts":[[2018,4,28]],"date-time":"2018-04-28T08:32:10Z","timestamp":1524904330000},"page":"171-191","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["How to Monitor the Neuroimmune Biological Response in Patients Affected by Immune Alteration-Related Systemic Diseases"],"prefix":"10.1007","author":[{"given":"Paolo","family":"Lissoni","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Franco","family":"Rovelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luigi","family":"Vigor\u00e8","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giusy","family":"Messina","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arianna","family":"Lissoni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giorgio","family":"Porro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Di Fede","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2018,4,29]]},"reference":[{"key":"10_CR1","first-page":"79","volume":"10","author":"DR Rubinow","year":"1987","unstructured":"Rubinow DR (1987) Brain, behaviour and immunity: an interactive system. J Natl Cancer Invest Monogr 10:79\u201382","journal-title":"J Natl Cancer Invest Monogr"},{"key":"10_CR2","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1038\/nri1806","volume":"6","author":"W Zou","year":"2006","unstructured":"Zou W (2006) Regulatory T cells, tumor immunity and immunotherapy. Nat Rev Immunol 6:295\u2013307","journal-title":"Nat Rev Immunol"},{"key":"10_CR3","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1016\/S0889-1591(02)00074-0","volume":"17","author":"MH Antony","year":"2003","unstructured":"Antony MH (2003) Psychoneuroimmunology of cancer. Brain Behav Immun 17:84\u201391","journal-title":"Brain Behav Immun"},{"key":"10_CR4","doi-asserted-by":"publisher","first-page":"466","DOI":"10.3181\/00379727-150-39057","volume":"150","author":"HO Besedovsky","year":"1975","unstructured":"Besedovsky HO, Sorkin E, Muller I (1975) Hormonal changes during immune response. Proc Soc Exp Biol Med 150:466\u2013471","journal-title":"Proc Soc Exp Biol Med"},{"key":"10_CR5","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1055\/s-2007-1012235","volume":"18","author":"P Lissoni","year":"1986","unstructured":"Lissoni P, Resentini M, Mauri R et al (1986) Effects of tetrahydrocannabinol on melatonin secretion in man. Horm Metab Res 18:77\u201378","journal-title":"Horm Metab Res"},{"key":"10_CR6","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1111\/j.1600-079X.1993.tb00478.x","volume":"14","author":"GJM Mestroni","year":"1993","unstructured":"Mestroni GJM (1993) The immunoneuronedocrine role of melatonin. J Pineal Res 14:1\u201310","journal-title":"J Pineal Res"},{"key":"10_CR7","doi-asserted-by":"publisher","first-page":"186","DOI":"10.1056\/NEJM199701163360306","volume":"336","author":"A Brzezinski","year":"1997","unstructured":"Brzezinski A (1997) Melatonin in humans. N Engl J Med 336:186\u2013195","journal-title":"N Engl J Med"},{"key":"10_CR8","doi-asserted-by":"publisher","first-page":"655","DOI":"10.1038\/bjc.1995.130","volume":"71","author":"RE Banks","year":"1995","unstructured":"Banks RE, Patel PM, Selby PJ (1995) Interleukin-12: a new clinical player in cytokine therapy. Br J Cancer 71:655\u2013659","journal-title":"Br J Cancer"},{"key":"10_CR9","doi-asserted-by":"publisher","first-page":"1823","DOI":"10.1084\/jem.155.6.1823","volume":"155","author":"EA Grimm","year":"1982","unstructured":"Grimm EA, Mazumder A, Zhang HZ et al (1982) Lymphokine-activated killer cell phenomenon. J Exp Med 155:1823\u20131841","journal-title":"J Exp Med"},{"key":"10_CR10","doi-asserted-by":"publisher","first-page":"436","DOI":"10.1038\/nature07205","volume":"454","author":"A Mantovani","year":"2008","unstructured":"Mantovani A, Allavena P, Sica A et al (2008) Cancer-related inflammation. Nature 454:436\u2013444","journal-title":"Nature"},{"key":"10_CR11","doi-asserted-by":"publisher","first-page":"2281","DOI":"10.1002\/cncr.20270","volume":"100","author":"R Kim","year":"2004","unstructured":"Kim R, Emi M, Tanabe K et al (2004) The role of Fas ligand and transfroming growth factor beta in tumor progression. Cancer 100:2281\u20132291","journal-title":"Cancer"},{"key":"10_CR12","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1016\/0165-5728(93)90266-2","volume":"44","author":"B Manfredi","year":"1993","unstructured":"Manfredi B, Sacerdote P, Bianchi M (1993) Evidence for an opioid inhibitory tone on T cell proliferation. J Neuroimmunol 44:43\u201346","journal-title":"J Neuroimmunol"},{"key":"10_CR13","first-page":"14","volume":"25","author":"F Grotehnermen","year":"2004","unstructured":"Grotehnermen F (2004) Pharmacology of cannabinoids. Neuroendocrinol Lett 25:14\u201323","journal-title":"Neuroendocrinol Lett"},{"key":"10_CR14","doi-asserted-by":"publisher","first-page":"1331","DOI":"10.1517\/13543784.17.9.1331","volume":"17","author":"S Aswell","year":"2008","unstructured":"Aswell S, Janetka JW, Zabludoff K (2008) Keeping checkpoin kinase in line: new selective inhibitors in clinical trials. Expert Opin Investig Drugs 17:1331\u20131340","journal-title":"Expert Opin Investig Drugs"},{"key":"10_CR15","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1093\/annonc\/mdv615","volume":"27","author":"J Chen","year":"2016","unstructured":"Chen J, Jiang CC, Jin L, Zhang XD (2016) Regulation of PD-L1: a novel role of pro-survival signaling in cancer. Ann Oncol 27:409\u2013416","journal-title":"Ann Oncol"},{"key":"10_CR16","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1126\/science.273.5271.70","volume":"273","author":"RA Miller","year":"1996","unstructured":"Miller RA (1996) The aging immune system: primer and prospectus. Science 273:70\u201374","journal-title":"Science"},{"key":"10_CR17","doi-asserted-by":"publisher","first-page":"1100","DOI":"10.1126\/science.7233204","volume":"212","author":"V Riley","year":"1981","unstructured":"Riley V (1981) Psychoneuroendocrine influence on immunocompetence and neoplasia. Science 212:1100\u20131109","journal-title":"Science"},{"key":"10_CR18","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1002\/(SICI)1097-0215(19970117)70:2<241::AID-IJC16>3.0.CO;2-L","volume":"70","author":"MC Mormont","year":"1997","unstructured":"Mormont MC, Levi D (1997) Circadian system alterations during cancer processes: a review. Int J Cancer 70:241\u2013247","journal-title":"Int J Cancer"},{"key":"10_CR19","first-page":"257","volume":"22","author":"P Lissoni","year":"2008","unstructured":"Lissoni P, Messina G, Balestra A et al (2008) Efficacy of cancer chemotherapy in relation to synchronization of cortisol rhythm, immune status and psychospiritual profile in metastatic non-small cell lung cancer. In Vivo 22:257\u2013262","journal-title":"In Vivo"},{"key":"10_CR20","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1007\/978-1-4615-4709-9_32","volume":"467","author":"C Bartsch","year":"1999","unstructured":"Bartsch C, Bartsch H (1999) Melatonin in cancer patients and in tuor-bearing animals. Adv Exp Med Biol 467:247\u2013264","journal-title":"Adv Exp Med Biol"},{"key":"10_CR21","first-page":"239","volume":"24","author":"F Brivio","year":"2010","unstructured":"Brivio F, Fumagalli L, Fumagalli G et al (2010) Synchronization of cortisol circadian rhythm by the pineal hormone melatonin in untreatable metastatic solid tumor patients and its possible prognostic signioficance on tumor progression. In Vivo 24:239\u2013242","journal-title":"In Vivo"},{"key":"10_CR22","first-page":"285","volume":"11","author":"P Lissoni","year":"1996","unstructured":"Lissoni P (1996) Prognostic markers in interleukin-2 therapy. Cancer Biother Radiopharm 11:285\u2013287","journal-title":"Cancer Biother Radiopharm"},{"key":"10_CR23","doi-asserted-by":"publisher","first-page":"407","DOI":"10.1038\/sj.bjc.6690371","volume":"80","author":"L Fumagalli","year":"1999","unstructured":"Fumagalli L, Lissoni P, Di Felice G (1999) Pretreatment serum markers and lymphocyte response to interleukin-2 therapy. Br J Cancer 80:407\u2013411","journal-title":"Br J Cancer"},{"key":"10_CR24","doi-asserted-by":"publisher","first-page":"485","DOI":"10.1146\/annurev.immunol.021908.132710","volume":"27","author":"T Korn","year":"2009","unstructured":"Korn T, Bettelli E, Oukka M, Kuchroo VK (2009) IL-17 and Th17 cells. Annu Rev Immunol 27:485\u2013517","journal-title":"Annu Rev Immunol"},{"key":"10_CR25","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1016\/j.semnephrol.2006.09.013","volume":"27","author":"CA Dinarello","year":"2007","unstructured":"Dinarello CA (2007) Interleukin-18 in the pathogenesis of inflammatory diseases. Semin Nephrol 27:98\u2013114","journal-title":"Semin Nephrol"},{"key":"10_CR26","doi-asserted-by":"publisher","first-page":"1672","DOI":"10.1097\/IGC.0b013e3182358955","volume":"21","author":"Y Tian","year":"2011","unstructured":"Tian Y, Yuan C, Ma D et al (2011) IL-21 and IL-12 inhibit differentiation of T reg and TH17 cells and enhance cytotoxicity of peripheral blood mononuclear cells in patients with cervical cancer. Int J Gynecol Cancer 21:1672\u20131678","journal-title":"Int J Gynecol Cancer"},{"key":"10_CR27","doi-asserted-by":"publisher","first-page":"637","DOI":"10.1097\/CCO.0000000000000006","volume":"25","author":"KL Dennis","year":"2013","unstructured":"Dennis KL, Blatner NR, Gounari F, Khazaie K (2013) Currents status of IL-10 and regulatory T-cells in cancer. Curr Opin Oncol 25:637\u2013645","journal-title":"Curr Opin Oncol"},{"key":"10_CR28","first-page":"647","volume":"22","author":"F Brivio","year":"2008","unstructured":"Brivio F, Fumagalli L, Parolini D et al (2008) T-helper\/T-regulatory lymphocyte ratio as a new immunobiological index to quantify the anticancer immune status in cancer patients. In Vivo 22:647\u2013650","journal-title":"In Vivo"},{"key":"10_CR29","doi-asserted-by":"publisher","first-page":"883","DOI":"10.1016\/j.cell.2010.01.025","volume":"295","author":"SI Grivennikov","year":"2010","unstructured":"Grivennikov SI, Greten FR, Karin M (2010) Immunity, inflammation, and cancer. Cell 295:883\u2013899","journal-title":"Cell"},{"key":"10_CR30","doi-asserted-by":"publisher","first-page":"289","DOI":"10.7150\/jca.13432","volume":"7","author":"WK Eo","year":"2016","unstructured":"Eo WK, Chang HJ, Kwon SH et al (2016) The lymphocyte-to-monocyte ratio predicts patient survival and aggressiveness of ovarian cancer. J Cancer 7:289\u2013296","journal-title":"J Cancer"},{"key":"10_CR31","doi-asserted-by":"publisher","first-page":"635","DOI":"10.1016\/0196-9781(83)90010-4","volume":"4","author":"JW Lewis","year":"1983","unstructured":"Lewis JW, Shavit Y, Terman GV (1983) Apparent involvement of opioids peptides in stress-induced enhancement of tumor growth. Peptides 4:635\u2013638","journal-title":"Peptides"},{"key":"10_CR32","doi-asserted-by":"publisher","first-page":"1381","DOI":"10.1016\/j.intimp.2009.08.008","volume":"9","author":"ATM Hassan","year":"2009","unstructured":"Hassan ATM, Hassan ZM, Moazzeni SM (2009) Naloxone can improve the antitumor immunity by reducing the CD4+CD25+Foxp3+ regulatory T cells in BALB\/c mice. Int J Immunopharmacol 9:1381\u20131386","journal-title":"Int J Immunopharmacol"},{"key":"10_CR33","doi-asserted-by":"publisher","first-page":"607","DOI":"10.1016\/0006-3002(61)90429-2","volume":"52","author":"WM McIsaac","year":"1961","unstructured":"McIsaac WM (1961) Formation of 1-methyl-6-methoxy-1,2,3,4-tetrahydro-2-carboline under physiological conditions. Biochem Biophys Acta 52:607\u2013610","journal-title":"Biochem Biophys Acta"},{"issue":"1","key":"10_CR34","first-page":"7","volume":"1","author":"P Lissoni","year":"2017","unstructured":"Lissoni P, Messina G, Tantarelli R et al (2017) The psychoneuroimmunotherapy of human immune-mediated systemic diseases, including cancer and autoimmune. J Mol Oncol Res 1(1):7\u201313","journal-title":"J Mol Oncol Res"},{"key":"10_CR35","first-page":"343","volume":"20","author":"P Lissoni","year":"1999","unstructured":"Lissoni P (1999) The pineal gland as central regulator of cytokine network. Neuroendocrinol Lett 20:343\u2013349","journal-title":"Neuroendocrinol Lett"},{"key":"10_CR36","doi-asserted-by":"publisher","first-page":"7183","DOI":"10.4049\/jimmunol.166.12.7183","volume":"166","author":"M Maccarone","year":"2001","unstructured":"Maccarone M, Valensise H, Bari M et al (2001) Progesterone up-regulates anandamide hydrolase in human lymphocytes: role of cytokines and implication in fertility. J Immunol 166:7183\u20137189","journal-title":"J Immunol"},{"key":"10_CR37","doi-asserted-by":"publisher","first-page":"106","DOI":"10.5306\/wjco.v8.i2.106","volume":"8","author":"PV Candelari","year":"2017","unstructured":"Candelari PV, Rampoldi A, Harbuzariv A et al (2017) Leptin signaling and cancer chemoresistance: perspectives. Word J Clin Oncol 8:106\u2013119","journal-title":"Word J Clin Oncol"},{"key":"10_CR38","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1111\/j.1600-6143.2008.02458.x","volume":"9","author":"BM Tesar","year":"2009","unstructured":"Tesar BM, Shirali AC, Walker WE et al (2009) Aging augments IL-17 T -cell alloimmune responses. Am J Transplant 9:54\u201363","journal-title":"Am J Transplant"},{"key":"10_CR39","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1016\/j.exger.2006.01.008","volume":"41","author":"C Dejaco","year":"2006","unstructured":"Dejaco C, Duftner C, Schirmer M (2006) Are regulatory T cells linked with aging? Exp Gerontol 41:339\u2013345","journal-title":"Exp Gerontol"},{"key":"10_CR40","first-page":"374","volume":"108","author":"IJ Elenkov","year":"1996","unstructured":"Elenkov IJ, Papanicolaou DA, Wilder RL et al (1996) Modulatory effects of glucocorticoids and cathecolamines on human interleukin-12 and interleukin-10 production: clinical implications. Proc Assoc Am Physicians 108:374\u2013381","journal-title":"Proc Assoc Am Physicians"},{"key":"10_CR41","doi-asserted-by":"publisher","first-page":"579","DOI":"10.1016\/j.imbio.2010.09.014","volume":"216","author":"IS Zagon","year":"2011","unstructured":"Zagon IS, Donahue RN, Bonneau RH et al (2011) T lymphocyte proliferation is suppressed by the opioid growth factor met (5)-enkephalin - opioid growth factor receptor axis: implication for the treatment of autoimmune diseases. Immunobiology 216:579\u2013590","journal-title":"Immunobiology"},{"key":"10_CR42","doi-asserted-by":"publisher","first-page":"172","DOI":"10.1186\/ar770","volume":"5","author":"A Aringer","year":"2003","unstructured":"Aringer A, Smolen JS (2003) Complex cytokine effects in a complex autoimmune disease: tumor necrosis factor in systemic lupus erythematosus. Arthritis Res Ther 5:172\u2013177","journal-title":"Arthritis Res Ther"},{"key":"10_CR43","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1136\/gut.52.1.65","volume":"52","author":"S Fujino","year":"2003","unstructured":"Fujino S, Andoh A, Bamba S et al (2003) Increased expression of interleukin-17 in inflammatory bowel disease. Gut 52:65\u201370","journal-title":"Gut"},{"issue":"5","key":"10_CR44","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1155\/MI.2005.273","volume":"2005","author":"O Arican","year":"2005","unstructured":"Arican O, Aral M, Sasmaz S et al (2005) Serum levels of TNF-alpha, IFN-gamma, IL-6, IL-8, IL-12, IL-17, and IL-18 in patients with active psoriasis and correlation with disease severity. Mediators Inflamm 2005(5):273\u2013279","journal-title":"Mediators Inflamm"},{"key":"10_CR45","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1084\/jem.20041257","volume":"201","author":"CL Langrish","year":"2005","unstructured":"Langrish CL, Chen Y, Blumenschein W et al (2005) Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation. J Exp Med 201:233\u2013240","journal-title":"J Exp Med"},{"key":"10_CR46","doi-asserted-by":"publisher","first-page":"447S","DOI":"10.1093\/ajcn\/83.2.447S","volume":"83","author":"CA Dinarello","year":"2006","unstructured":"Dinarello CA (2006) Interleukin 1 and interleukin 18 as mediators of inflammation and the aging process. Am J Clin Nutr 83:447S\u2013455S","journal-title":"Am J Clin Nutr"},{"key":"10_CR47","doi-asserted-by":"publisher","first-page":"2785","DOI":"10.1084\/jem.20061341","volume":"203","author":"J Lohr","year":"2006","unstructured":"Lohr J, Knoechel B, Wang J et al (2006) Role of IL-17 and regulatory T lymphocytes in a systemic autoimmune disease. J Exp Med 203:2785\u20132791","journal-title":"J Exp Med"},{"key":"10_CR48","doi-asserted-by":"crossref","first-page":"96","DOI":"10.47102\/annals-acadmedsg.V36N2p96","volume":"36","author":"SS Paramalingam","year":"2007","unstructured":"Paramalingam SS, Thumboo J, Vasoo S et al (2007) In vivo pro- and anti-inflammatory cytokines in normal and patients with rheumatoid arthritis. Ann Acad Med Singapore 36:96\u201399","journal-title":"Ann Acad Med Singapore"},{"key":"10_CR49","doi-asserted-by":"publisher","first-page":"8","DOI":"10.2353\/ajpath.2008.070862","volume":"172","author":"R Gold","year":"2008","unstructured":"Gold R, Luhder F (2008) Interleukin-17. Extended features of a key player in multiple sclerosis. Am J Pathol 172:8\u201310","journal-title":"Am J Pathol"},{"key":"10_CR50","doi-asserted-by":"publisher","first-page":"1167","DOI":"10.2353\/ajpath.2009.090319","volume":"175","author":"GE Katsifis","year":"2009","unstructured":"Katsifis GE, Rekka S, Moutsopoulos NM et al (2009) Systemic and local interleukin-17 and linked cytokines associated with Sjogren\u2019s syndrome immunopathogenesis. Am J Pathol 175:1167\u20131177","journal-title":"Am J Pathol"},{"key":"10_CR51","doi-asserted-by":"publisher","first-page":"4169","DOI":"10.4049\/jimmunol.0901017","volume":"183","author":"G Murugaiyan","year":"2009","unstructured":"Murugaiyan G, Saha B (2009) Protumor vs antitumor functions of IL-17. J Immunol 183:4169\u20134175","journal-title":"J Immunol"},{"key":"10_CR52","doi-asserted-by":"publisher","first-page":"1226","DOI":"10.1038\/mi.2015.13","volume":"8","author":"OJ Harrison","year":"2015","unstructured":"Harrison OJ, Srinivasan N, Pott J, Schiering C et al (2015) Epithelial-derived IL-18 regulates Th17 cell differentiation and Foxp3+ T reg cell function in the intestine. Mucosal Immunol 8:1226\u20131236","journal-title":"Mucosal Immunol"},{"key":"10_CR53","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1111\/imm.12263","volume":"142","author":"J Lee","year":"2014","unstructured":"Lee J, Shin EK, Lee SY et al (2014) Oestrogen up-regulates interleukin-21 production by CD4+ T lymphocytes in patients with systemic lupus erythematosus. Immunology 142:573\u2013580","journal-title":"Immunology"},{"key":"10_CR54","doi-asserted-by":"publisher","first-page":"1424","DOI":"10.1161\/CIRCULATIONAHA.108.827618","volume":"119","author":"RE Eid","year":"1982","unstructured":"Eid RE, Rao DA, Zhou J et al (1982) Interleukin-17 and interferon-gamma are produced concomitantly by human coronary artery-infiltrating T cells and act synergistically on vascular smooth muscle cells. Circulation 119:1424\u20131432","journal-title":"Circulation"},{"key":"10_CR55","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1186\/s40035-016-0054-4","volume":"5","author":"C Zheng","year":"2016","unstructured":"Zheng C, Zhou XW, Wang JZ (2016) The dual role of cytokines in Alzheimer\u2019s disease: update on interleukins, TNF-alpha, TGF-beta and IFN-gamma. Transl Neurodegener 5:7\u201318","journal-title":"Transl Neurodegener"},{"key":"10_CR56","first-page":"230","volume":"16","author":"MJ Ehrke","year":"1982","unstructured":"Ehrke MJ, Mihich E, Berd D et al (1982) Effects of anticancer drugs on the immune system in humans. Semin Oncol 16:230\u2013239","journal-title":"Semin Oncol"},{"key":"10_CR57","first-page":"1847","volume":"29","author":"P Lissoni","year":"2009","unstructured":"Lissoni P, Brivio F, Fumagalli L et al (2009) Effects of the conventional antitumor therapies: surgery, chemotherapy, radiotherapy and immunotherapy on regulatory T lymphocytes in cancer patients. Anticancer Res 29:1847\u20131852","journal-title":"Anticancer Res"}],"container-title":["Methods in Molecular Biology","Psychoneuroimmunology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/978-1-4939-7828-1_10","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,2]],"date-time":"2023-09-02T09:55:48Z","timestamp":1693648548000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/978-1-4939-7828-1_10"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018]]},"ISBN":["9781493978274","9781493978281"],"references-count":57,"URL":"https:\/\/doi.org\/10.1007\/978-1-4939-7828-1_10","relation":{},"ISSN":["1064-3745","1940-6029"],"issn-type":[{"type":"print","value":"1064-3745"},{"type":"electronic","value":"1940-6029"}],"subject":[],"published":{"date-parts":[[2018]]},"assertion":[{"value":"29 April 2018","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}}]}}