{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T02:39:42Z","timestamp":1790044782575,"version":"4.0.1"},"publisher-location":"New York, NY","reference-count":19,"publisher":"Springer New York","isbn-type":[{"value":"9781493989935","type":"print"},{"value":"9781493989942","type":"electronic"}],"license":[{"start":{"date-parts":[[2018,12,11]],"date-time":"2018-12-11T00:00:00Z","timestamp":1544486400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019]]},"DOI":"10.1007\/978-1-4939-8994-2_14","type":"book-chapter","created":{"date-parts":[[2018,12,10]],"date-time":"2018-12-10T19:21:18Z","timestamp":1544469678000},"page":"149-155","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Characterization of an Animal Model of Autism and Social Interaction"],"prefix":"10.1007","author":[{"given":"Keiko","family":"Iwata","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,12,11]]},"reference":[{"key":"14_CR1","doi-asserted-by":"publisher","first-page":"896","DOI":"10.1016\/S0140-6736(13)61539-1","volume":"383","author":"MC Lai","year":"2014","unstructured":"Lai MC, Lombardo MV, Baron-Cohen S (2014) Autism. Lancet 383:896\u2013910","journal-title":"Lancet"},{"key":"14_CR2","doi-asserted-by":"publisher","first-page":"943","DOI":"10.1038\/35103559","volume":"2","author":"SE Folstein","year":"2001","unstructured":"Folstein SE, Rosen-Sheidley B (2001) Genetics of autism: complex aetiology for a heterogeneous disorder. Nat Rev Genet 2:943\u2013955","journal-title":"Nat Rev Genet"},{"key":"14_CR3","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1016\/j.jns.2008.08.021","volume":"280","author":"DA Geier","year":"2009","unstructured":"Geier DA, Kern JK, Garver CR, Adams JB, Audhya T, Nataf R et al (2009) Biomarkers of environmental toxicity and susceptibility in autism. J Neurol Sci 280:101\u2013108","journal-title":"J Neurol Sci"},{"key":"14_CR4","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1177\/1744629507083585","volume":"11","author":"A Gillott","year":"2007","unstructured":"Gillott A, Standen PJ (2007) Levels of anxiety and sources of stress in adults with autism. J Intellect Disabil 11:359\u2013370","journal-title":"J Intellect Disabil"},{"key":"14_CR5","doi-asserted-by":"publisher","first-page":"1519","DOI":"10.1016\/j.neubiorev.2008.06.004","volume":"32","author":"DK Kinney","year":"2008","unstructured":"Kinney DK, Munir KM, Crowley DJ, Miller AM (2008) Prenatal stress and risk for autism. Neurosci Biobehav Rev 32:1519\u20131532","journal-title":"Neurosci Biobehav Rev"},{"key":"14_CR6","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1080\/13550280590900553","volume":"11","author":"JE Libbey","year":"2005","unstructured":"Libbey JE, Sweeten TL, McMahon WM, Fujinami RS (2005) Autistic disorder and viral infections. J Neurovirol 11:1\u201310","journal-title":"J Neurovirol"},{"key":"14_CR7","doi-asserted-by":"publisher","first-page":"1423","DOI":"10.1007\/s10803-010-1006-y","volume":"40","author":"HO Atladottir","year":"2010","unstructured":"Atladottir HO, Thorsen P, Ostergaard L, Schendel DE, Lemcke S, Abdallah M et al (2010) Maternal infection requiring hospitalization during pregnancy and autism spectrum disorders. J Autism Dev Disord 40:1423\u20131430","journal-title":"J Autism Dev Disord"},{"key":"14_CR8","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1016\/j.bbi.2014.09.001","volume":"44","author":"BK Lee","year":"2015","unstructured":"Lee BK, Magnusson C, Gardner RM, Blomstrom A, Newschaffer CJ, Burstyn I et al (2015) Maternal hospitalization with infection during pregnancy and risk of autism spectrum disorders. Brain Behav Immun 44:100\u2013105","journal-title":"Brain Behav Immun"},{"key":"14_CR9","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1038\/mp.2012.197","volume":"19","author":"AS Brown","year":"2014","unstructured":"Brown AS, Sourander A, Hinkka-Yli-Salomaki S, McKeague IW, Sundvall J, Surcel HM (2014) Elevated maternal C-reactive protein and autism in a national birth cohort. Mol Psychiatry 19:259\u2013264","journal-title":"Mol Psychiatry"},{"key":"14_CR10","doi-asserted-by":"publisher","first-page":"4015","DOI":"10.1007\/s10803-013-2016-3","volume":"45","author":"O Zerbo","year":"2015","unstructured":"Zerbo O, Qian YG, Yoshida C, Grether JK, Van de Water J, Croen LA (2015) Maternal infection during pregnancy and autism spectrum disorders. J Autism Dev Disord 45:4015\u20134025","journal-title":"J Autism Dev Disord"},{"key":"14_CR11","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1186\/2040-2392-2-13","volume":"2","author":"PE Goines","year":"2011","unstructured":"Goines PE, Croen LA, Braunschweig D, Yoshida CK, Grether J, Hansen R et al (2011) Increased midgestational IFN-gamma, IL-4 and IL-5 in women bearing a child with autism: a case-control study. Mol Autism 2:13. \nhttps:\/\/doi.org\/10.1186\/2040-2392-2-13","journal-title":"Mol Autism"},{"key":"14_CR12","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1016\/j.bbi.2016.06.005","volume":"58","author":"HY Jiang","year":"2016","unstructured":"Jiang HY, Xu LL, Shao L, Xia RM, Yu ZH, Ling ZX et al (2016) Maternal infection during pregnancy and risk of autism spectrum disorders: a systematic review and meta-analysis. Brain Behav Immun 58:165\u2013172","journal-title":"Brain Behav Immun"},{"key":"14_CR13","doi-asserted-by":"publisher","first-page":"931","DOI":"10.1016\/0028-3908(79)90157-6","volume":"18","author":"T Robbins","year":"1979","unstructured":"Robbins T, Sahakian B (1979) \"paradoxical\" effects of psychomotor stimulant drugs in hyperactive children from the standpoint of behavioural pharmacology. Neuropharmacology 18:931\u2013950","journal-title":"Neuropharmacology"},{"key":"14_CR14","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1007\/s10519-006-9120-5","volume":"37","author":"S Tordjman","year":"2007","unstructured":"Tordjman S, Drapier D, Bonnot O, Graignic R, Fortes S, Cohen D et al (2007) Animal models relevant to schizophrenia and autism: validity and limitations. Behav Genet 37:61\u201378","journal-title":"Behav Genet"},{"key":"14_CR15","doi-asserted-by":"publisher","first-page":"37","DOI":"10.4137\/JCNSD.S6188","volume":"2","author":"K Iwata","year":"2010","unstructured":"Iwata K, Matsuzaki H, Takei N, Manabe T, Mori N (2010) Animal models of autism: an epigenetic and environmental viewpoint. J Cent Nerv Syst Dis 2:37\u201344","journal-title":"J Cent Nerv Syst Dis"},{"key":"14_CR16","doi-asserted-by":"publisher","first-page":"607","DOI":"10.1016\/j.bbi.2012.01.011","volume":"26","author":"NV Malkova","year":"2012","unstructured":"Malkova NV, Yu CZ, Hsiao EY, Moore MJ, Patterson PH (2012) Maternal immune activation yields offspring displaying mouse versions of the three core symptoms of autism. Brain Behav Immun 26:607\u2013616","journal-title":"Brain Behav Immun"},{"key":"14_CR17","doi-asserted-by":"publisher","first-page":"10695","DOI":"10.1523\/JNEUROSCI.2178-07.2007","volume":"27","author":"SE Smith","year":"2007","unstructured":"Smith SE, Li J, Garbett K, Mirnics K, Patterson PH (2007) Maternal immune activation alters fetal brain development through interleukin-6. J Neurosci 27:10695\u201310702","journal-title":"J Neurosci"},{"key":"14_CR18","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1111\/j.1601-1848.2004.00076.x","volume":"3","author":"SS Moy","year":"2004","unstructured":"Moy SS, Nadler JJ, Perez A, Barbaro RP, Johns JM, Magnuson TR et al (2004) Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice. Genes Brain Behav 3:287\u2013302","journal-title":"Genes Brain Behav"},{"key":"14_CR19","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1111\/j.1601-183X.2004.00071.x","volume":"3","author":"JJ Nadler","year":"2004","unstructured":"Nadler JJ, Moy SS, Dold G, Trang D, Simmons N, Perez A et al (2004) Automated apparatus for quantitation of social approach behaviors in mice. Genes Brain Behav 3:303\u2013314","journal-title":"Genes Brain Behav"}],"container-title":["Methods in Molecular Biology","Pre-Clinical Models"],"original-title":[],"link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/978-1-4939-8994-2_14","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,12,10]],"date-time":"2018-12-10T19:25:58Z","timestamp":1544469958000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/978-1-4939-8994-2_14"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,12,11]]},"ISBN":["9781493989935","9781493989942"],"references-count":19,"URL":"https:\/\/doi.org\/10.1007\/978-1-4939-8994-2_14","relation":{},"ISSN":["1064-3745","1940-6029"],"issn-type":[{"value":"1064-3745","type":"print"},{"value":"1940-6029","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,12,11]]}}}