{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,25]],"date-time":"2025-03-25T23:02:39Z","timestamp":1742943759479,"version":"3.40.3"},"publisher-location":"New York, NY","reference-count":25,"publisher":"Springer New York","isbn-type":[{"type":"print","value":"9781493991471"},{"type":"electronic","value":"9781493991488"}],"license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019]]},"DOI":"10.1007\/978-1-4939-9148-8_28","type":"book-chapter","created":{"date-parts":[[2019,3,13]],"date-time":"2019-03-13T07:02:38Z","timestamp":1552460558000},"page":"381-395","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Isolation and Phenotypic Characterization of Inflammatory Cells from Clinical Samples: Purification of Macrophages from Trypanosoma cruzi-Infected Hearts"],"prefix":"10.1007","author":[{"given":"Natalia","family":"Eberhardt","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liliana Mar\u00eda","family":"Sanmarco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Pilar","family":"Aoki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2019,3,14]]},"reference":[{"issue":"11","key":"28_CR1","doi-asserted-by":"publisher","first-page":"673","DOI":"10.1111\/j.1365-3024.2009.01108.x","volume":"31","author":"FR Gutierrez","year":"2009","unstructured":"Gutierrez FR, Guedes PM, Gazzinelli RT, Silva JS (2009) The role of parasite persistence in pathogenesis of Chagas heart disease. Parasite Immunol 31(11):673\u2013685. \n                  https:\/\/doi.org\/10.1111\/j.1365-3024.2009.01108.x","journal-title":"Parasite Immunol"},{"issue":"9","key":"28_CR2","doi-asserted-by":"publisher","first-page":"1109","DOI":"10.1161\/CIRCULATIONAHA.106.624296","volume":"115","author":"JA Marin-Neto","year":"2007","unstructured":"Marin-Neto JA, Cunha-Neto E, Maciel BC, Simoes MV (2007) Pathogenesis of chronic Chagas heart disease. Circulation 115(9):1109\u20131123. \n                  https:\/\/doi.org\/10.1161\/CIRCULATIONAHA.106.624296","journal-title":"Circulation"},{"issue":"9723","key":"28_CR3","doi-asserted-by":"publisher","first-page":"1388","DOI":"10.1016\/S0140-6736(10)60061-X","volume":"375","author":"A Rassi Jr","year":"2010","unstructured":"Rassi A Jr, Rassi A, Marin-Neto JA (2010) Chagas disease. Lancet 375(9723):1388\u20131402. S0140-6736(10)60061-X. \n                  https:\/\/doi.org\/10.1016\/S0140-6736(10)60061-X","journal-title":"Lancet"},{"issue":"3","key":"28_CR4","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0150606","volume":"11","author":"YR Yu","year":"2016","unstructured":"Yu YR, O\u2019Koren EG, Hotten DF, Kan MJ, Kopin D, Nelson ER, Que L, Gunn MD (2016) A protocol for the comprehensive flow cytometric analysis of immune cells in normal and inflamed murine non-lymphoid tissues. PLoS One 11(3):e0150606. \n                  https:\/\/doi.org\/10.1371\/journal.pone.0150606","journal-title":"PLoS One"},{"issue":"2","key":"28_CR5","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1038\/nri3800","volume":"15","author":"S Epelman","year":"2015","unstructured":"Epelman S, Liu PP, Mann DL (2015) Role of innate and adaptive immune mechanisms in cardiac injury and repair. Nat Rev Immunol 15(2):117\u2013129. \n                  https:\/\/doi.org\/10.1038\/nri3800","journal-title":"Nat Rev Immunol"},{"issue":"1","key":"28_CR6","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1161\/CIRCRESAHA.117.311071","volume":"122","author":"L Honold","year":"2018","unstructured":"Honold L, Nahrendorf M (2018) Resident and monocyte-derived macrophages in cardiovascular disease. Circ Res 122(1):113\u2013127. \n                  https:\/\/doi.org\/10.1161\/CIRCRESAHA.117.311071","journal-title":"Circ Res"},{"issue":"10","key":"28_CR7","doi-asserted-by":"publisher","first-page":"986","DOI":"10.1038\/ni.2705","volume":"14","author":"LC Davies","year":"2013","unstructured":"Davies LC, Jenkins SJ, Allen JE, Taylor PR (2013) Tissue-resident macrophages. Nat Immunol 14(10):986\u2013995. \n                  https:\/\/doi.org\/10.1038\/ni.2705","journal-title":"Nat Immunol"},{"issue":"3","key":"28_CR8","doi-asserted-by":"publisher","first-page":"814","DOI":"10.4049\/jimmunol.1600371","volume":"197","author":"NE Ponce","year":"2016","unstructured":"Ponce NE, Sanmarco LM, Eberhardt N, Garcia MC, Rivarola HW, Cano RC, Aoki MP (2016) CD73 inhibition shifts cardiac macrophage polarization toward a microbicidal phenotype and ameliorates the outcome of experimental Chagas cardiomyopathy. J Immunol 197(3):814\u2013823. \n                  https:\/\/doi.org\/10.4049\/jimmunol.1600371","journal-title":"J Immunol"},{"issue":"4","key":"28_CR9","doi-asserted-by":"publisher","first-page":"857","DOI":"10.1016\/j.bbadis.2017.01.006","volume":"1863","author":"LM Sanmarco","year":"2017","unstructured":"Sanmarco LM, Ponce NE, Visconti LM, Eberhardt N, Theumer MG, Minguez AR, Aoki MP (2017) IL-6 promotes M2 macrophage polarization by modulating purinergic signaling and regulates the lethal release of nitric oxide during Trypanosoma cruzi infection. Biochim Biophys Acta 1863(4):857\u2013869. \n                  https:\/\/doi.org\/10.1016\/j.bbadis.2017.01.006","journal-title":"Biochim Biophys Acta"},{"issue":"12","key":"28_CR10","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0145342","volume":"10","author":"KA Jablonski","year":"2015","unstructured":"Jablonski KA, Amici SA, Webb LM, Ruiz-Rosado Jde D, Popovich PG, Partida-Sanchez S, Guerau-de-Arellano M (2015) Novel markers to delineate murine M1 and M2 macrophages. PLoS One 10(12):e0145342. \n                  https:\/\/doi.org\/10.1371\/journal.pone.0145342","journal-title":"PLoS One"},{"key":"28_CR11","doi-asserted-by":"publisher","first-page":"1921","DOI":"10.3389\/fimmu.2017.01921","volume":"8","author":"LM Sanmarco","year":"2017","unstructured":"Sanmarco LM, Eberhardt N, Ponce NE, Cano RC, Bonacci G, Aoki MP (2017) New insights into the immunobiology of mononuclear phagocytic cells and their relevance to the pathogenesis of cardiovascular diseases. Front Immunol 8:1921. \n                  https:\/\/doi.org\/10.3389\/fimmu.2017.01921","journal-title":"Front Immunol"},{"issue":"12","key":"28_CR12","doi-asserted-by":"publisher","first-page":"13400","DOI":"10.18632\/oncotarget.7630","volume":"7","author":"ME Cabalen","year":"2016","unstructured":"Cabalen ME, Cabral MF, Sanmarco LM, Andrada MC, Onofrio LI, Ponce NE, Aoki MP, Gea S, Cano RC (2016) Chronic Trypanosoma cruzi infection potentiates adipose tissue macrophage polarization toward an anti-inflammatory M2 phenotype and contributes to diabetes progression in a diet-induced obesity model. Oncotarget 7(12):13400\u201313415. \n                  https:\/\/doi.org\/10.18632\/oncotarget.7630","journal-title":"Oncotarget"},{"issue":"6","key":"28_CR13","doi-asserted-by":"publisher","first-page":"463","DOI":"10.1615\/CritRevImmunol.v32.i6.10","volume":"32","author":"CD Mills","year":"2012","unstructured":"Mills CD (2012) M1 and M2 macrophages: oracles of health and disease. Crit Rev Immunol 32(6):463\u2013488","journal-title":"Crit Rev Immunol"},{"issue":"12","key":"28_CR14","doi-asserted-by":"publisher","first-page":"958","DOI":"10.1038\/nri2448","volume":"8","author":"DM Mosser","year":"2008","unstructured":"Mosser DM, Edwards JP (2008) Exploring the full spectrum of macrophage activation. Nat Rev Immunol 8(12):958\u2013969. \n                  https:\/\/doi.org\/10.1038\/nri2448","journal-title":"Nat Rev Immunol"},{"key":"28_CR15","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2014.00532","volume":"5","author":"M Rath","year":"2014","unstructured":"Rath M, Muller I, Kropf P, Closs EI, Munder M (2014) Metabolism via arginase or nitric oxide synthase: two competing arginine pathways in macrophages. Front Immunol 5:532. \n                  https:\/\/doi.org\/10.3389\/fimmu.2014.00532","journal-title":"Front Immunol"},{"issue":"3","key":"28_CR16","doi-asserted-by":"publisher","first-page":"1507","DOI":"10.1038\/nprot.2006.268","volume":"1","author":"L Lamoreaux","year":"2006","unstructured":"Lamoreaux L, Roederer M, Koup R (2006) Intracellular cytokine optimization and standard operating procedure. Nat Protoc 1(3):1507\u20131516. \n                  https:\/\/doi.org\/10.1038\/nprot.2006.268","journal-title":"Nat Protoc"},{"key":"28_CR17","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1016\/j.jim.2016.06.007","volume":"436","author":"R Davies","year":"2016","unstructured":"Davies R, Vogelsang P, Jonsson R, Appel S (2016) An optimized multiplex flow cytometry protocol for the analysis of intracellular signaling in peripheral blood mononuclear cells. J Immunol Methods 436:58\u201363. \n                  https:\/\/doi.org\/10.1016\/j.jim.2016.06.007","journal-title":"J Immunol Methods"},{"key":"28_CR18","doi-asserted-by":"publisher","unstructured":"Foster B, Prussin C, Liu F, Whitmire JK, Whitton JL (2007) Detection of intracellular cytokines by flow cytometry. Curr Protoc Immunol. Chapter 6:Unit 6 24. \n                  https:\/\/doi.org\/10.1002\/0471142735.im0624s78","DOI":"10.1002\/0471142735.im0624s78"},{"key":"28_CR19","doi-asserted-by":"publisher","unstructured":"McLarty JL, Melendez GC, Spencer WJ, Levick SP, Brower GL, Janicki JS (2011) Isolation of functional cardiac immune cells. J Vis Exp 58. \n                  https:\/\/doi.org\/10.3791\/3020","DOI":"10.3791\/3020"},{"key":"28_CR20","doi-asserted-by":"publisher","unstructured":"Roederer M (2002) Compensation in flow cytometry. Curr Protoc Cytom. Chapter 1:Unit 1 14. \n                  https:\/\/doi.org\/10.1002\/0471142956.cy0114s22","DOI":"10.1002\/0471142956.cy0114s22"},{"issue":"3","key":"28_CR21","doi-asserted-by":"publisher","first-page":"194","DOI":"10.1002\/1097-0320(20011101)45:3<194::AID-CYTO1163>3.0.CO;2-C","volume":"45","author":"M Roederer","year":"2001","unstructured":"Roederer M (2001) Spectral compensation for flow cytometry: visualization artifacts, limitations, and caveats. Cytometry 45(3):194\u2013205","journal-title":"Cytometry"},{"issue":"11","key":"28_CR22","doi-asserted-by":"publisher","first-page":"982","DOI":"10.1002\/cyto.a.22736","volume":"87","author":"G Szaloki","year":"2015","unstructured":"Szaloki G, Goda K (2015) Compensation in multicolor flow cytometry. Cytometry A 87(11):982\u2013985. \n                  https:\/\/doi.org\/10.1002\/cyto.a.22736","journal-title":"Cytometry A"},{"key":"28_CR23","doi-asserted-by":"publisher","DOI":"10.1155\/2011\/184731","volume":"2011","author":"NM Rodijnen van","year":"2011","unstructured":"van Rodijnen NM, Pieters M, Hoop S, Nap M (2011) Data-driven compensation for flow cytometry of solid tissues. Adv Bioinforma 2011:184731. \n                  https:\/\/doi.org\/10.1155\/2011\/184731","journal-title":"Adv Bioinforma"},{"issue":"10","key":"28_CR24","doi-asserted-by":"publisher","first-page":"1584","DOI":"10.1002\/eji.201646632","volume":"47","author":"A Cossarizza","year":"2017","unstructured":"Cossarizza A, Chang HD, Radbruch A, Akdis M, Andra I, Annunziato F, Bacher P, Barnaba V, Battistini L, Bauer WM, Baumgart S, Becher B, Beisker W, Berek C, Blanco A, Borsellino G, Boulais PE, Brinkman RR, Buscher M, Busch DH, Bushnell TP, Cao X, Cavani A, Chattopadhyay PK, Cheng Q, Chow S, Clerici M, Cooke A, Cosma A, Cosmi L, Cumano A, Dang VD, Davies D, De Biasi S, Del Zotto G, Della Bella S, Dellabona P, Deniz G, Dessing M, Diefenbach A, Di Santo J, Dieli F, Dolf A, Donnenberg VS, Dorner T, Ehrhardt GRA, Endl E, Engel P, Engelhardt B, Esser C, Everts B, Dreher A, Falk CS, Fehniger TA, Filby A, Fillatreau S, Follo M, Forster I, Foster J, Foulds GA, Frenette PS, Galbraith D, Garbi N, Garcia-Godoy MD, Geginat J, Ghoreschi K, Gibellini L, Goettlinger C, Goodyear CS, Gori A, Grogan J, Gross M, Grutzkau A, Grummitt D, Hahn J, Hammer Q, Hauser AE, Haviland DL, Hedley D, Herrera G, Herrmann M, Hiepe F, Holland T, Hombrink P, Houston JP, Hoyer BF, Huang B, Hunter CA, Iannone A, Jack HM, Javega B, Jonjic S, Juelke K, Jung S, Kaiser T, Kalina T, Keller B, Khan S, Kienhofer D, Kroneis T, Kunkel D, Kurts C, Kvistborg P, Lannigan J, Lantz O, Larbi A, LeibundGut-Landmann S, Leipold MD, Levings MK, Litwin V, Liu Y, Lohoff M, Lombardi G, Lopez L, Lovett-Racke A, Lubberts E, Ludewig B, Lugli E, Maecker HT, Martrus G, Matarese G, Maueroder C, McGrath M, McInnes I, Mei HE, Melchers F, Melzer S, Mielenz D, Mills K, Mirrer D, Mjosberg J, Moore J, Moran B, Moretta A, Moretta L, Mosmann TR, Muller S, Muller W, Munz C, Multhoff G, Munoz LE, Murphy KM, Nakayama T, Nasi M, Neudorfl C, Nolan J, Nourshargh S, O\u2019Connor JE, Ouyang W, Oxenius A, Palankar R, Panse I, Peterson P, Peth C, Petriz J, Philips D, Pickl W, Piconese S, Pinti M, Pockley AG, Podolska MJ, Pucillo C, Quataert SA, Radstake T, Rajwa B, Rebhahn JA, Recktenwald D, Remmerswaal EBM, Rezvani K, Rico LG, Robinson JP, Romagnani C, Rubartelli A, Ruckert B, Ruland J, Sakaguchi S, Sala-de-Oyanguren F, Samstag Y, Sanderson S, Sawitzki B, Scheffold A, Schiemann M, Schildberg F, Schimisky E, Schmid SA, Schmitt S, Schober K, Schuler T, Schulz AR, Schumacher T, Scotta C, Shankey TV, Shemer A, Simon AK, Spidlen J, Stall AM, Stark R, Stehle C, Stein M, Steinmetz T, Stockinger H, Takahama Y, Tarnok A, Tian Z, Toldi G, Tornack J, Traggiai E, Trotter J, Ulrich H, van der Braber M, van Lier RAW, Veldhoen M, Vento-Asturias S, Vieira P, Voehringer D, Volk HD, von Volkmann K, Waisman A, Walker R, Ward MD, Warnatz K, Warth S, Watson JV, Watzl C, Wegener L, Wiedemann A, Wienands J, Willimsky G, Wing J, Wurst P, Yu L, Yue A, Zhang Q, Zhao Y, Ziegler S, Zimmermann J (2017) Guidelines for the use of flow cytometry and cell sorting in immunological studies. Eur J Immunol 47(10):1584\u20131797. \n                  https:\/\/doi.org\/10.1002\/eji.201646632","journal-title":"Eur J Immunol"},{"issue":"1","key":"28_CR25","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1038\/nprot.2014.005","volume":"9","author":"KG Anderson","year":"2014","unstructured":"Anderson KG, Mayer-Barber K, Sung H, Beura L, James BR, Taylor JJ, Qunaj L, Griffith TS, Vezys V, Barber DL, Masopust D (2014) Intravascular staining for discrimination of vascular and tissue leukocytes. Nat Protoc 9(1):209\u2013222. \n                  https:\/\/doi.org\/10.1038\/nprot.2014.005","journal-title":"Nat Protoc"}],"container-title":["Methods in Molecular Biology","T. cruzi Infection"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/978-1-4939-9148-8_28","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,17]],"date-time":"2019-05-17T05:31:15Z","timestamp":1558071075000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/978-1-4939-9148-8_28"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019]]},"ISBN":["9781493991471","9781493991488"],"references-count":25,"URL":"https:\/\/doi.org\/10.1007\/978-1-4939-9148-8_28","relation":{},"ISSN":["1064-3745","1940-6029"],"issn-type":[{"type":"print","value":"1064-3745"},{"type":"electronic","value":"1940-6029"}],"subject":[],"published":{"date-parts":[[2019]]},"assertion":[{"value":"14 March 2019","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}}]}}