{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T09:51:27Z","timestamp":1792662687397,"version":"4.5.0"},"publisher-location":"New York, NY","reference-count":26,"publisher":"Springer New York","isbn-type":[{"value":"9781493991662","type":"print"},{"value":"9781493991679","type":"electronic"}],"license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019]]},"DOI":"10.1007\/978-1-4939-9167-9_20","type":"book-chapter","created":{"date-parts":[[2019,2,23]],"date-time":"2019-02-23T09:00:07Z","timestamp":1550912407000},"page":"227-236","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":43,"title":["Modeling Autism-Related Disorders in Mice with Maternal Immune Activation (MIA)"],"prefix":"10.1007","author":[{"given":"Catherine R.","family":"Lammert","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John R.","family":"Lukens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,2,24]]},"reference":[{"issue":"2","key":"20_CR1","doi-asserted-by":"publisher","first-page":"687","DOI":"10.1542\/peds.2008-2445","volume":"124","author":"HO Atladottir","year":"2009","unstructured":"Atladottir HO, Pedersen MG, Thorsen P et al (2009) Association of family history of autoimmune diseases and autism spectrum disorders. Pediatrics 124(2):687\u2013694. \n                  https:\/\/doi.org\/10.1542\/peds.2008-2445","journal-title":"Pediatrics"},{"issue":"12","key":"20_CR2","doi-asserted-by":"publisher","first-page":"1423","DOI":"10.1007\/s10803-010-1006-y","volume":"40","author":"HO Atladottir","year":"2010","unstructured":"Atladottir HO, Thorsen P, Ostergaard L et al (2010) Maternal infection requiring hospitalization during pregnancy and autism spectrum disorders. J Autism Dev Disord 40(12):1423\u20131430. \n                  https:\/\/doi.org\/10.1007\/s10803-010-1006-y","journal-title":"J Autism Dev Disord"},{"issue":"7","key":"20_CR3","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1016\/j.molmed.2011.03.001","volume":"17","author":"PH Patterson","year":"2011","unstructured":"Patterson PH (2011) Maternal infection and immune involvement in autism. Trends Mol Med 17(7):389\u2013394. \n                  https:\/\/doi.org\/10.1016\/j.molmed.2011.03.001","journal-title":"Trends Mol Med"},{"issue":"2","key":"20_CR4","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1001\/archpsyc.1988.01800260109013","volume":"45","author":"SA Mednick","year":"1988","unstructured":"Mednick SA, Machon RA, Huttunen MO et al (1988) Adult schizophrenia following prenatal exposure to an influenza epidemic. Arch Gen Psychiatry 45(2):189\u2013192","journal-title":"Arch Gen Psychiatry"},{"issue":"2","key":"20_CR5","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1093\/oxfordjournals.schbul.a033453","volume":"26","author":"AS Brown","year":"2000","unstructured":"Brown AS, Schaefer CA, Wyatt RJ et al (2000) Maternal exposure to respiratory infections and adult schizophrenia spectrum disorders: a prospective birth cohort study. Schizophr Bull 26(2):287\u2013295","journal-title":"Schizophr Bull"},{"issue":"1","key":"20_CR6","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1007\/BF01537741","volume":"1","author":"S Chess","year":"1971","unstructured":"Chess S (1971) Autism in children with congenital rubella. J Autism Child Schizophr 1(1):33\u201347","journal-title":"J Autism Child Schizophr"},{"issue":"1","key":"20_CR7","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1007\/BF01531116","volume":"7","author":"S Chess","year":"1977","unstructured":"Chess S (1977) Follow-up report on autism in congenital rubella. J Autism Child Schizophr 7(1):69\u201381","journal-title":"J Autism Child Schizophr"},{"issue":"4","key":"20_CR8","doi-asserted-by":"publisher","first-page":"699","DOI":"10.1016\/S0022-3476(78)80921-4","volume":"93","author":"S Chess","year":"1978","unstructured":"Chess S, Fernandez P, Korn S (1978) Behavioral consequences of congenital rubella. J Pediatr 93(4):699\u2013703","journal-title":"J Pediatr"},{"issue":"11","key":"20_CR9","doi-asserted-by":"publisher","first-page":"1171","DOI":"10.1038\/mp.2013.101","volume":"18","author":"L Brimberg","year":"2013","unstructured":"Brimberg L, Sadiq A, Gregersen PK et al (2013) Brain-reactive IgG correlates with autoimmunity in mothers of a child with an autism spectrum disorder. Mol Psychiatry 18(11):1171\u20131177. \n                  https:\/\/doi.org\/10.1038\/mp.2013.101","journal-title":"Mol Psychiatry"},{"issue":"11","key":"20_CR10","doi-asserted-by":"publisher","first-page":"643","DOI":"10.1038\/nrneurol.2014.187","volume":"10","author":"I Knuesel","year":"2014","unstructured":"Knuesel I, Chicha L, Britschgi M et al (2014) Maternal immune activation and abnormal brain development across CNS disorders. Nat Rev Neurol 10(11):643\u2013660. \n                  https:\/\/doi.org\/10.1038\/nrneurol.2014.187","journal-title":"Nat Rev Neurol"},{"issue":"8","key":"20_CR11","doi-asserted-by":"publisher","first-page":"469","DOI":"10.1038\/nrn3978","volume":"16","author":"ML Estes","year":"2015","unstructured":"Estes ML, McAllister AK (2015) Immune mediators in the brain and peripheral tissues in autism spectrum disorder. Nat Rev Neurosci 16(8):469\u2013486. \n                  https:\/\/doi.org\/10.1038\/nrn3978","journal-title":"Nat Rev Neurosci"},{"issue":"6","key":"20_CR12","doi-asserted-by":"publisher","first-page":"693","DOI":"10.1001\/archneurol.2011.2506","volume":"69","author":"D Braunschweig","year":"2012","unstructured":"Braunschweig D, Van de Water J (2012) Maternal autoantibodies in autism. Arch Neurol 69(6):693\u2013699. \n                  https:\/\/doi.org\/10.1001\/archneurol.2011.2506","journal-title":"Arch Neurol"},{"issue":"6","key":"20_CR13","doi-asserted-by":"publisher","first-page":"628","DOI":"10.1093\/oxfordjournals.aje.a112726","volume":"109","author":"EY Deykin","year":"1979","unstructured":"Deykin EY, MacMahon B (1979) Viral exposure and autism. Am J Epidemiol 109(6):628\u2013638","journal-title":"Am J Epidemiol"},{"issue":"10","key":"20_CR14","doi-asserted-by":"publisher","first-page":"1778","DOI":"10.1038\/sj.npp.1300248","volume":"28","author":"L Zuckerman","year":"2003","unstructured":"Zuckerman L, Rehavi M, Nachman R et al (2003) Immune activation during pregnancy in rats leads to a postpubertal emergence of disrupted latent inhibition, dopaminergic hyperfunction, and altered limbic morphology in the offspring: a novel neurodevelopmental model of schizophrenia. Neuropsychopharmacology 28(10):1778\u20131789. \n                  https:\/\/doi.org\/10.1038\/sj.npp.1300248","journal-title":"Neuropsychopharmacology"},{"issue":"3","key":"20_CR15","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1016\/j.jpsychires.2004.08.008","volume":"39","author":"L Zuckerman","year":"2005","unstructured":"Zuckerman L, Weiner I (2005) Maternal immune activation leads to behavioral and pharmacological changes in the adult offspring. J Psychiatr Res 39(3):311\u2013323. \n                  https:\/\/doi.org\/10.1016\/j.jpsychires.2004.08.008","journal-title":"J Psychiatr Res"},{"issue":"1","key":"20_CR16","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1523\/JNEUROSCI.23-01-00297.2003","volume":"23","author":"L Shi","year":"2003","unstructured":"Shi L, Fatemi SH, Sidwell RW et al (2003) Maternal influenza infection causes marked behavioral and pharmacological changes in the offspring. J Neurosci 23(1):297\u2013302","journal-title":"J Neurosci"},{"issue":"40","key":"20_CR17","doi-asserted-by":"publisher","first-page":"10695","DOI":"10.1523\/JNEUROSCI.2178-07.2007","volume":"27","author":"SE Smith","year":"2007","unstructured":"Smith SE, Li J, Garbett K et al (2007) Maternal immune activation alters fetal brain development through interleukin-6. J Neurosci 27(40):10695\u201310702. \n                  https:\/\/doi.org\/10.1523\/JNEUROSCI.2178-07.2007","journal-title":"J Neurosci"},{"issue":"4","key":"20_CR18","doi-asserted-by":"publisher","first-page":"607","DOI":"10.1016\/j.bbi.2012.01.011","volume":"26","author":"NV Malkova","year":"2012","unstructured":"Malkova NV, Yu CZ, Hsiao EY et al (2012) Maternal immune activation yields offspring displaying mouse versions of the three core symptoms of autism. Brain Behav Immun 26(4):607\u2013616. \n                  https:\/\/doi.org\/10.1016\/j.bbi.2012.01.011","journal-title":"Brain Behav Immun"},{"issue":"7","key":"20_CR19","doi-asserted-by":"publisher","first-page":"1451","DOI":"10.1016\/j.cell.2013.11.024","volume":"155","author":"EY Hsiao","year":"2013","unstructured":"Hsiao EY, McBride SW, Hsien S et al (2013) Microbiota modulate behavioral and physiological abnormalities associated with neurodevelopmental disorders. Cell 155(7):1451\u20131463. \n                  https:\/\/doi.org\/10.1016\/j.cell.2013.11.024","journal-title":"Cell"},{"issue":"6276","key":"20_CR20","doi-asserted-by":"publisher","first-page":"933","DOI":"10.1126\/science.aad0314","volume":"351","author":"GB Choi","year":"2016","unstructured":"Choi GB, Yim YS, Wong H et al (2016) The maternal interleukin-17a pathway in mice promotes autism-like phenotypes in offspring. Science 351(6276):933\u2013939. \n                  https:\/\/doi.org\/10.1126\/science.aad0314","journal-title":"Science"},{"issue":"7673","key":"20_CR21","doi-asserted-by":"publisher","first-page":"482","DOI":"10.1038\/nature23909","volume":"549","author":"Y Shin Yim","year":"2017","unstructured":"Shin Yim Y, Park A, Berrios J et\u00a0al (2017) Reversing behavioural abnormalities in mice exposed to maternal inflammation. Nature 549(7673):482\u2013487. \n                  https:\/\/doi.org\/10.1038\/nature23909","journal-title":"Nature"},{"issue":"7673","key":"20_CR22","doi-asserted-by":"publisher","first-page":"528","DOI":"10.1038\/nature23910","volume":"549","author":"S Kim","year":"2017","unstructured":"Kim S, Kim H, Yim YS et al (2017) Maternal gut bacteria promote neurodevelopmental abnormalities in mouse offspring. Nature 549(7673):528\u2013532. \n                  https:\/\/doi.org\/10.1038\/nature23910","journal-title":"Nature"},{"issue":"3","key":"20_CR23","doi-asserted-by":"publisher","first-page":"1299","DOI":"10.1016\/j.neuropharm.2011.02.022","volume":"62","author":"Y Zhang","year":"2012","unstructured":"Zhang Y, Cazakoff BN, Thai CA et al (2012) Prenatal exposure to a viral mimetic alters behavioural flexibility in male, but not female, rats. Neuropharmacology 62(3):1299\u20131307. \n                  https:\/\/doi.org\/10.1016\/j.neuropharm.2011.02.022","journal-title":"Neuropharmacology"},{"issue":"6","key":"20_CR24","doi-asserted-by":"publisher","first-page":"1383","DOI":"10.1073\/pnas.1619312114","volume":"114","author":"SM Schaafsma","year":"2017","unstructured":"Schaafsma SM, Gagnidze K, Reyes A et al (2017) Sex-specific gene-environment interactions underlying ASD-like behaviors. Proc Natl Acad Sci U S A 114(6):1383\u20131388. \n                  https:\/\/doi.org\/10.1073\/pnas.1619312114","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"2","key":"20_CR25","doi-asserted-by":"publisher","first-page":"146","DOI":"10.1097\/WCO.0b013e32835ee548","volume":"26","author":"DM Werling","year":"2013","unstructured":"Werling DM, Geschwind DH (2013) Sex differences in autism spectrum disorders. Curr Opin Neurol 26(2):146\u2013153. \n                  https:\/\/doi.org\/10.1097\/WCO.0b013e32835ee548","journal-title":"Curr Opin Neurol"},{"issue":"5","key":"20_CR26","doi-asserted-by":"publisher","first-page":"417","DOI":"10.3109\/09540261.2010.515205","volume":"22","author":"KM Abel","year":"2010","unstructured":"Abel KM, Drake R, Goldstein JM (2010) Sex differences in schizophrenia. Int Rev Psychiatry 22(5):417\u2013428. \n                  https:\/\/doi.org\/10.3109\/09540261.2010.515205","journal-title":"Int Rev Psychiatry"}],"container-title":["Methods in Molecular Biology","Mouse Models of Innate Immunity"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/978-1-4939-9167-9_20","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,17]],"date-time":"2019-05-17T05:39:56Z","timestamp":1558071596000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/978-1-4939-9167-9_20"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019]]},"ISBN":["9781493991662","9781493991679"],"references-count":26,"URL":"https:\/\/doi.org\/10.1007\/978-1-4939-9167-9_20","relation":{},"ISSN":["1064-3745","1940-6029"],"issn-type":[{"value":"1064-3745","type":"print"},{"value":"1940-6029","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019]]},"assertion":[{"value":"24 February 2019","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}}]}}