{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,13]],"date-time":"2026-11-13T23:53:43Z","timestamp":1794614023504,"version":"4.9.1"},"publisher-location":"New York, NY","reference-count":9,"publisher":"Springer New York","isbn-type":[{"value":"9781493997169","type":"print"},{"value":"9781493997176","type":"electronic"}],"license":[{"start":{"date-parts":[[2019,10,24]],"date-time":"2019-10-24T00:00:00Z","timestamp":1571875200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020]]},"DOI":"10.1007\/978-1-4939-9717-6_24","type":"book-chapter","created":{"date-parts":[[2019,10,23]],"date-time":"2019-10-23T13:28:26Z","timestamp":1571837306000},"page":"323-334","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Assays to Measure Purinoceptor Pore Dilation"],"prefix":"10.1007","author":[{"given":"Ben J.","family":"Gu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pavan","family":"Avula","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James S.","family":"Wiley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,10,24]]},"reference":[{"key":"24_CR1","doi-asserted-by":"publisher","first-page":"1013","DOI":"10.1152\/physrev.00015.2002","volume":"82","author":"RA North","year":"2002","unstructured":"North RA (2002) Molecular physiology of P2X receptors. Physiol Rev 82:1013\u20131067","journal-title":"Physiol Rev"},{"key":"24_CR2","doi-asserted-by":"publisher","first-page":"3877","DOI":"10.4049\/jimmunol.176.7.3877","volume":"176","author":"D Ferrari","year":"2006","unstructured":"Ferrari D, Pizzirani C, Adinolfi E, Lemoli RM, Curti A, Idzko M, Panther E, Di Virgilio F (2006) The P2X7 receptor: a key player in IL-1 processing and release. J Immunol 176:3877\u20133883","journal-title":"J Immunol"},{"key":"24_CR3","doi-asserted-by":"publisher","first-page":"908","DOI":"10.1111\/j.1476-5381.2011.01325.x","volume":"163","author":"P Pelegrin","year":"2011","unstructured":"Pelegrin P (2011) Many ways to dilate the P2X7 receptor pore. Br J Pharmacol 163:908\u2013911","journal-title":"Br J Pharmacol"},{"key":"24_CR4","doi-asserted-by":"publisher","first-page":"1577","DOI":"10.1038\/nn.4120","volume":"18","author":"M Li","year":"2015","unstructured":"Li M, Toombes GE, Silberberg SD, Swartz KJ (2015) Physical basis of apparent pore dilation of ATP-activated P2X receptor channels. Nat Neurosci 18:1577\u20131583","journal-title":"Nat Neurosci"},{"key":"24_CR5","doi-asserted-by":"publisher","first-page":"C1224","DOI":"10.1152\/ajpcell.1998.275.5.C1224","volume":"44","author":"JS Wiley","year":"1998","unstructured":"Wiley JS, Gargett CE, Zhang W, Snook MB, Jamieson GA (1998) Partial agonists and antagonists reveal a second permeability state of human lymphocyte P2Z\/P2X7 channel. Am J Phys Cell Phys 44:C1224\u2013C1231","journal-title":"Am J Phys Cell Phys"},{"key":"24_CR6","doi-asserted-by":"publisher","first-page":"C430","DOI":"10.1152\/ajpcell.00079.2009","volume":"297","author":"BJ Gu","year":"2009","unstructured":"Gu BJ, Rathsam C, Stokes L, McGeachie AB, Wiley JS (2009) Extracellular ATP dissociates nonmuscle myosin from P2X(7) complex: this dissociation regulates P2X7 pore formation. Am J Physiol Cell Physiol 297:C430\u2013C439","journal-title":"Am J Physiol Cell Physiol"},{"key":"24_CR7","doi-asserted-by":"publisher","first-page":"C1189","DOI":"10.1152\/ajpcell.2000.279.4.C1189","volume":"279","author":"BJ Gu","year":"2000","unstructured":"Gu BJ, Zhang WY, Bendall LJ, Chessell IP, Buell GN, Wiley JS (2000) Expression of P2X7 purinoceptors on human lymphocytes and monocytes: evidence for nonfunctional P2X7 receptors. Am J Phys Cell Phys 279:C1189\u2013C1197","journal-title":"Am J Phys Cell Phys"},{"key":"24_CR8","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1016\/j.jim.2007.06.002","volume":"325","author":"C Jursik","year":"2007","unstructured":"Jursik C, Sluyter R, Georgiou JG, Fuller SJ, Wiley JS, Gu BJ (2007) A quantitative method for routine measurement of cell surface P2X7 receptor function in leucocyte subsets by two-colour time-resolved flow cytometry. J Immunol Methods 325:67\u201377","journal-title":"J Immunol Methods"},{"key":"24_CR9","first-page":"185","volume-title":"Flow cytometry: recent perspectives","author":"BJ Gu","year":"2012","unstructured":"Gu BJ, Wiley JS (2012) Broad applications of multi-colour time-resolved flow cytometry. In: Schmid I (ed) Flow cytometry: recent perspectives. InTech, Croatia, pp 185\u2013202"}],"container-title":["Methods in Molecular Biology","Purinergic Signaling"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/978-1-4939-9717-6_24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,10,23]],"date-time":"2019-10-23T13:32:23Z","timestamp":1571837543000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/978-1-4939-9717-6_24"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10,24]]},"ISBN":["9781493997169","9781493997176"],"references-count":9,"URL":"https:\/\/doi.org\/10.1007\/978-1-4939-9717-6_24","relation":{"is-part-of":[{"id-type":"doi","id":"https:\/\/doi.org\/10.1007\/978-1-4939-9717-6","asserted-by":"object"}]},"ISSN":["1064-3745","1940-6029"],"issn-type":[{"value":"1064-3745","type":"print"},{"value":"1940-6029","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,10,24]]},"assertion":[{"value":"24 October 2019","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}}]}}