{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,11]],"date-time":"2024-09-11T13:03:45Z","timestamp":1726059825150},"publisher-location":"New York, NY","reference-count":30,"publisher":"Springer US","isbn-type":[{"type":"print","value":"9781493998562"},{"type":"electronic","value":"9781493998579"}],"license":[{"start":{"date-parts":[[2019,11,23]],"date-time":"2019-11-23T00:00:00Z","timestamp":1574467200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020]]},"DOI":"10.1007\/978-1-4939-9857-9_14","type":"book-chapter","created":{"date-parts":[[2019,11,22]],"date-time":"2019-11-22T13:03:08Z","timestamp":1574427788000},"page":"245-268","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Measuring Solute Transport in Toxoplasma gondii Parasites"],"prefix":"10.1007","author":[{"given":"Esther","family":"Rajendran","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kiaran","family":"Kirk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giel G.","family":"van Dooren","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2019,11,23]]},"reference":[{"issue":"6","key":"14_CR1","doi-asserted-by":"publisher","first-page":"e78","DOI":"10.1371\/journal.ppat.0030078","volume":"3","author":"B Striepen","year":"2007","unstructured":"Striepen B, Jordan CN, Reiff S, van Dooren GG (2007) Building the perfect parasite: cell division in apicomplexa. PLoS Pathog 3(6):e78","journal-title":"PLoS Pathog"},{"issue":"9425","key":"14_CR2","doi-asserted-by":"publisher","first-page":"1965","DOI":"10.1016\/S0140-6736(04)16412-X","volume":"363","author":"JG Montoya","year":"2004","unstructured":"Montoya JG, Liesenfeld O (2004) Toxoplasmosis. Lancet 363(9425):1965\u20131976","journal-title":"Lancet"},{"key":"14_CR3","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.06974","volume":"4","author":"YH Woo","year":"2015","unstructured":"Woo YH, Ansari H, Otto TD, Klinger CM, Kolisko M, Michalek J et al (2015) Chromerid genomes reveal the evolutionary path from photosynthetic algae to obligate intracellular parasites. Elife 4:e06974","journal-title":"Elife"},{"issue":"4","key":"14_CR4","doi-asserted-by":"publisher","first-page":"R174","DOI":"10.1016\/j.cub.2015.12.057","volume":"26","author":"J Janouskovec","year":"2016","unstructured":"Janouskovec J, Keeling PJ (2016) Evolution: causality and the origin of parasitism. Curr Biol 26(4):R174\u2013R177","journal-title":"Curr Biol"},{"issue":"5","key":"14_CR5","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1004261","volume":"11","author":"S Tymoshenko","year":"2015","unstructured":"Tymoshenko S, Oppenheim RD, Agren R, Nielsen J, Soldati-Favre D, Hatzimanikatis V (2015) Metabolic needs and capabilities of Toxoplasma gondii through combined computational and experimental analysis. PLoS Comput Biol 11(5):e1004261","journal-title":"PLoS Comput Biol"},{"key":"14_CR6","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1146\/annurev-micro-092412-155741","volume":"67","author":"GG Dooren van","year":"2013","unstructured":"van Dooren GG, Striepen B (2013) The algal past and parasite present of the apicoplast. Annu Rev Microbiol 67:271\u2013289","journal-title":"Annu Rev Microbiol"},{"issue":"31","key":"14_CR7","doi-asserted-by":"publisher","first-page":"12998","DOI":"10.1073\/pnas.0903831106","volume":"106","author":"M Blume","year":"2009","unstructured":"Blume M, Rodriguez-Contreras D, Landfear S, Fleige T, Soldati-Favre D, Lucius R et al (2009) Host-derived glucose and its transporter in the obligate intracellular pathogen Toxoplasma gondii are dispensable by glutaminolysis. Proc Natl Acad Sci U S A 106(31):12998\u201313003","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"5","key":"14_CR8","doi-asserted-by":"publisher","first-page":"682","DOI":"10.1016\/j.chom.2012.09.013","volume":"12","author":"JI MacRae","year":"2012","unstructured":"MacRae JI, Sheiner L, Nahid A, Tonkin C, Striepen B, McConville MJ (2012) Mitochondrial metabolism of glucose and glutamine is required for intracellular growth of Toxoplasma gondii. Cell Host Microbe 12(5):682\u2013692","journal-title":"Cell Host Microbe"},{"issue":"2","key":"14_CR9","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1016\/j.ijpara.2013.09.003","volume":"44","author":"I Coppens","year":"2014","unstructured":"Coppens I (2014) Exploitation of auxotrophies and metabolic defects in Toxoplasma as therapeutic approaches. Int J Parasitol 44(2):109\u2013120","journal-title":"Int J Parasitol"},{"issue":"Pt 15","key":"14_CR10","doi-asserted-by":"crossref","first-page":"3049","DOI":"10.1242\/jcs.115.15.3049","volume":"115","author":"AJ Charron","year":"2002","unstructured":"Charron AJ, Sibley LD (2002) Host cells: mobilizable lipid resources for the intracellular parasite Toxoplasma gondii. J Cell Sci 115(Pt 15):3049\u20133059","journal-title":"J Cell Sci"},{"issue":"3","key":"14_CR11","doi-asserted-by":"publisher","first-page":"323","DOI":"10.1016\/j.ijpara.2003.12.001","volume":"34","author":"BA Fox","year":"2004","unstructured":"Fox BA, Gigley JP, Bzik DJ (2004) Toxoplasma gondii lacks the enzymes required for de novo arginine biosynthesis and arginine starvation triggers cyst formation. Int J Parasitol 34(3):323\u2013331","journal-title":"Int J Parasitol"},{"issue":"2","key":"14_CR12","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1007577","volume":"15","author":"KER Parker","year":"2019","unstructured":"Parker KER, Fairweather SJ, Rajendran E, Blume M, McConville MJ, Br\u00f6er S et al (2019) The tyrosine transporter of Toxoplasma gondii is a member of the newly defined apicomplexan amino acid transporter (ApiAT) family. PLoS Pathog 15(2):e1007577","journal-title":"PLoS Pathog"},{"issue":"4","key":"14_CR13","doi-asserted-by":"publisher","first-page":"886","DOI":"10.1016\/j.cmet.2018.02.018","volume":"27","author":"L Pernas","year":"2018","unstructured":"Pernas L, Bean C, Boothroyd JC, Scorrano L (2018) Mitochondria restrict growth of the intracellular parasite Toxoplasma gondii by limiting its uptake of fatty acids. Cell Metab 27(4):886\u201397 e4","journal-title":"Cell Metab"},{"issue":"3","key":"14_CR14","doi-asserted-by":"publisher","first-page":"908","DOI":"10.1073\/pnas.81.3.908","volume":"81","author":"ER Pfefferkorn","year":"1984","unstructured":"Pfefferkorn ER (1984) Interferon gamma blocks the growth of Toxoplasma gondii in human fibroblasts by inducing the host cells to degrade tryptophan. Proc Natl Acad Sci U S A 81(3):908\u2013912","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"1","key":"14_CR15","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1016\/0014-4894(82)90094-7","volume":"53","author":"JD Schwartzman","year":"1982","unstructured":"Schwartzman JD, Pfefferkorn ER (1982) Toxoplasma gondii: purine synthesis and salvage in mutant host cells and parasites. Exp Parasitol 53(1):77\u201386","journal-title":"Exp Parasitol"},{"key":"14_CR16","doi-asserted-by":"publisher","DOI":"10.1038\/nmicrobiol.2017.96","volume":"2","author":"M Cristina Di","year":"2017","unstructured":"Di Cristina M, Dou Z, Lunghi M, Kannan G, Huynh MH, McGovern OL et al (2017) Toxoplasma depends on lysosomal consumption of autophagosomes for persistent infection. Nat Microbiol 2:17096","journal-title":"Nat Microbiol"},{"issue":"Pt 3","key":"14_CR17","doi-asserted-by":"publisher","first-page":"923","DOI":"10.1042\/bj20021189","volume":"368","author":"T Joet","year":"2002","unstructured":"Joet T, Holterman L, Stedman TT, Kocken CH, Van Der Wel A, Thomas AW et al (2002) Comparative characterization of hexose transporters of Plasmodium knowlesi, Plasmodium yoelii and Toxoplasma gondii highlights functional differences within the apicomplexan family. Biochem J 368(Pt 3):923\u2013929","journal-title":"Biochem J"},{"issue":"49","key":"14_CR18","doi-asserted-by":"publisher","first-page":"35255","DOI":"10.1074\/jbc.274.49.35255","volume":"274","author":"CW Chiang","year":"1999","unstructured":"Chiang CW, Carter N, Sullivan WJ Jr, Donald RG, Roos DS, Naguib FN et al (1999) The adenosine transporter of Toxoplasma gondii. Identification by insertional mutagenesis, cloning, and recombinant expression. J Biol Chem 274(49):35255\u201335261","journal-title":"J Biol Chem"},{"key":"14_CR19","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms14455","volume":"8","author":"E Rajendran","year":"2017","unstructured":"Rajendran E, Hapuarachchi SV, Miller CM, Fairweather SJ, Cai Y, Smith NC et al (2017) Cationic amino acid transporters play key roles in the survival and transmission of apicomplexan parasites. Nat Commun 8:14455","journal-title":"Nat Commun"},{"issue":"1","key":"14_CR20","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1074\/jbc.M114.624619","volume":"291","author":"R Nitzsche","year":"2016","unstructured":"Nitzsche R, Zagoriy V, Lucius R, Gupta N (2016) Metabolic cooperation of glucose and glutamine is essential for the lytic cycle of obligate intracellular parasite Toxoplasma gondii. J Biol Chem 291(1):126\u2013141","journal-title":"J Biol Chem"},{"issue":"6","key":"14_CR21","doi-asserted-by":"publisher","first-page":"1423","DOI":"10.1016\/j.cell.2016.08.019","volume":"166","author":"SM Sidik","year":"2016","unstructured":"Sidik SM, Huet D, Ganesan SM, Huynh MH, Wang T, Nasamu AS et al (2016) A genome-wide CRISPR screen in Toxoplasma identifies essential apicomplexan genes. Cell 166(6):1423\u20131435","journal-title":"Cell"},{"issue":"14","key":"14_CR22","doi-asserted-by":"publisher","first-page":"10683","DOI":"10.1074\/jbc.275.14.10683","volume":"275","author":"NS Carter","year":"2000","unstructured":"Carter NS, Ben Mamoun C, Liu W, Silva EO, Landfear SM, Goldberg DE et al (2000) Isolation and functional characterization of the PfNT1 nucleoside transporter gene from Plasmodium falciparum. J Biol Chem 275(14):10683\u201310691","journal-title":"J Biol Chem"},{"issue":"3","key":"14_CR23","doi-asserted-by":"publisher","first-page":"478","DOI":"10.1016\/j.cell.2015.07.022","volume":"162","author":"A Cesar-Razquin","year":"2015","unstructured":"Cesar-Razquin A, Snijder B, Frappier-Brinton T, Isserlin R, Gyimesi G, Bai X et al (2015) A call for systematic research on solute carriers. Cell 162(3):478\u2013487","journal-title":"Cell"},{"issue":"8","key":"14_CR24","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1038\/nrd4626","volume":"14","author":"L Lin","year":"2015","unstructured":"Lin L, Yee SW, Kim RB, Giacomini KM (2015) SLC transporters as therapeutic targets: emerging opportunities. Nat Rev Drug Discov 14(8):543\u2013560","journal-title":"Nat Rev Drug Discov"},{"issue":"2","key":"14_CR25","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1006180","volume":"13","author":"SV Hapuarachchi","year":"2017","unstructured":"Hapuarachchi SV, Cobbold SA, Shafik SH, Dennis AS, McConville MJ, Martin RE et al (2017) The malaria parasite\u2019s lactate transporter PfFNT is the target of antiplasmodial compounds identified in whole cell phenotypic screens. PLoS Pathog 13(2):e1006180","journal-title":"PLoS Pathog"},{"issue":"2","key":"14_CR26","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1111\/mmi.12765","volume":"94","author":"AM Lehane","year":"2014","unstructured":"Lehane AM, Ridgway MC, Baker E, Kirk K (2014) Diverse chemotypes disrupt ion homeostasis in the malaria parasite. Mol Microbiol 94(2):327\u2013339","journal-title":"Mol Microbiol"},{"issue":"8","key":"14_CR27","doi-asserted-by":"publisher","first-page":"821","DOI":"10.1016\/S0020-7519(03)00091-2","volume":"33","author":"HP Koning De","year":"2003","unstructured":"De Koning HP, Al-Salabi MI, Cohen AM, Coombs GH, Wastling JM (2003) Identification and characterisation of high affinity nucleoside and nucleobase transporters in Toxoplasma gondii. Int J Parasitol 33(8):821\u2013831","journal-title":"Int J Parasitol"},{"issue":"1","key":"14_CR28","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1042\/BJ20131007","volume":"457","author":"K Kirk","year":"2014","unstructured":"Kirk K, Lehane AM (2014) Membrane transport in the malaria parasite and its host erythrocyte. Biochem J 457(1):1\u201318","journal-title":"Biochem J"},{"issue":"6","key":"14_CR29","doi-asserted-by":"publisher","first-page":"1069","DOI":"10.1039\/C6MD00005C","volume":"7","author":"C Colas","year":"2016","unstructured":"Colas C, Ung PM, Schlessinger A (2016) SLC transporters: structure, function, and drug discovery. Medchemcomm 7(6):1069\u20131081","journal-title":"Medchemcomm"},{"issue":"1-2","key":"14_CR30","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1016\/0166-6851(95)00005-L","volume":"70","author":"JC Schwab","year":"1995","unstructured":"Schwab JC, Afifi Afifi M, Pizzorno G, Handschumacher RE, Joiner KA (1995) Toxoplasma gondii tachyzoites possess an unusual plasma membrane adenosine transporter. Mol Biochem Parasitol 70(1-2):59\u201369","journal-title":"Mol Biochem Parasitol"}],"container-title":["Methods in Molecular Biology","Toxoplasma gondii"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/978-1-4939-9857-9_14","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,10,6]],"date-time":"2022-10-06T18:43:15Z","timestamp":1665081795000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/978-1-4939-9857-9_14"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11,23]]},"ISBN":["9781493998562","9781493998579"],"references-count":30,"URL":"https:\/\/doi.org\/10.1007\/978-1-4939-9857-9_14","relation":{},"ISSN":["1064-3745","1940-6029"],"issn-type":[{"type":"print","value":"1064-3745"},{"type":"electronic","value":"1940-6029"}],"subject":[],"published":{"date-parts":[[2019,11,23]]},"assertion":[{"value":"23 November 2019","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}}]}}