{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,11]],"date-time":"2026-11-11T02:17:59Z","timestamp":1794363479847,"version":"4.9.0"},"publisher-location":"Totowa, NJ","reference-count":7,"publisher":"Humana Press","isbn-type":[{"value":"9781588299079","type":"print"},{"value":"9781597452410","type":"electronic"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2009]]},"DOI":"10.1007\/978-1-59745-241-0_22","type":"book-chapter","created":{"date-parts":[[2009,5,5]],"date-time":"2009-05-05T15:51:28Z","timestamp":1241538688000},"page":"343-355","source":"Crossref","is-referenced-by-count":6,"title":["The Cranial Bone Window Model: Studying Angiogenesis of Primary and Secondary Bone Tumors by Intravital Microscopy"],"prefix":"10.1007","author":[{"given":"Axel","family":"Sckell","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank M.","family":"Klenke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2008,10,31]]},"reference":[{"key":"22_CR1_22","doi-asserted-by":"publisher","first-page":"519","DOI":"10.1016\/0167-5699(93)90179-O","volume":"14","author":"M D Menger","year":"1993","unstructured":"Menger, M. D., Lehr, H. A. (1993) Scope and perspectives of intravital microscopy - bridge over from in vitro to in vivo. Immunol Today 14, 519\u2013522.","journal-title":"Immunol Today"},{"key":"22_CR2_22","first-page":"413","volume":"6","author":"M Leunig","year":"1995","unstructured":"Leunig, M., Messmer, K. (1995) Intravital microscopy in tumor biology: current status and future perspectives (review). Int J Oncol 6, 413\u2013417.","journal-title":"Int J Oncol"},{"key":"22_CR3_22","doi-asserted-by":"publisher","first-page":"1203","DOI":"10.1038\/nm1197-1203","volume":"3","author":"R K Jain","year":"1997","unstructured":"Jain, R. K., Schlenger, K., H\u00f6ckel, M., Yuan, F. (1997) Quantitative angiogenesis assays: progress and problems. Nat Med 3, 1203\u20131208.","journal-title":"Nat Med"},{"key":"22_CR4_22","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1258\/002367705774286411","volume":"39","author":"F M Klenke","year":"2005","unstructured":"Klenke, F. M., Merkle, T., Fellenberg, J., (2005) A novel model for the investigation of orthotopically growing primary and secondary bone tumors using intravital microscopy. Lab Anim 39, 377\u2013383.","journal-title":"Lab Anim"},{"key":"22_CR5_22","doi-asserted-by":"publisher","first-page":"9.","DOI":"10.1186\/1471-2407-6-9","volume":"6","author":"F M Klenke","year":"2006","unstructured":"Klenke, F. M., Gebhard, M. M., Ewerbeck, V., Abdollahi, A., Huber, P. E., Sckell, A. (2006) The selective Cox-2 inhibitor Celecoxib suppresses angiogenesis and growth of secondary bone tumors: an intravital microscopy study in mice. BMC Cancer 6, 9.","journal-title":"BMC Cancer"},{"key":"22_CR6_22","first-page":"4564","volume":"54","author":"F Yuan","year":"1994","unstructured":"Yuan, F., Salehi, H. A., Boucher, Y., Vasthare, U. S., Tuma, R. F., Jain, R. K. (1994) Vascular permeability and microcirculation of gliomas and mammary carcinomas transplanted in rat and mouse cranial windows. Cancer Res 54, 4564\u20134568.","journal-title":"Cancer Res"},{"key":"22_CR7_22","first-page":"5866","volume":"58","author":"A Sckell","year":"1998","unstructured":"Sckell, A., Safabakhsh, N., Dellian, M., Jain, R. K. (1998) Primary tumor size-dependent inhibition of angiogenesis at a secondary site: an intravital microscopic study in mice. Cancer Res 58, 5866\u20135869.","journal-title":"Cancer Res"}],"container-title":["Methods in Molecular Biology","Angiogenesis Protocols"],"original-title":[],"link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/978-1-59745-241-0_22.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,11,18]],"date-time":"2020-11-18T14:48:44Z","timestamp":1605710924000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/978-1-59745-241-0_22"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,10,31]]},"ISBN":["9781588299079","9781597452410"],"references-count":7,"URL":"https:\/\/doi.org\/10.1007\/978-1-59745-241-0_22","relation":{"is-part-of":[{"id-type":"doi","id":"https:\/\/doi.org\/10.1007\/978-1-59745-241-0","asserted-by":"object"}]},"ISSN":["1064-3745","1940-6029"],"issn-type":[{"value":"1064-3745","type":"print"},{"value":"1940-6029","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,10,31]]}}}