{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,10]],"date-time":"2026-11-10T23:30:44Z","timestamp":1794353444495,"version":"4.9.0"},"publisher-location":"Totowa, NJ","reference-count":19,"publisher":"Humana Press","isbn-type":[{"value":"9781588299062","type":"print"},{"value":"9781597452427","type":"electronic"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2008]]},"DOI":"10.1007\/978-1-59745-242-7_6","type":"book-chapter","created":{"date-parts":[[2008,2,13]],"date-time":"2008-02-13T13:53:29Z","timestamp":1202910809000},"page":"75-84","source":"Crossref","is-referenced-by-count":16,"title":["The Avian Embryo in Fetal Alcohol Research"],"prefix":"10.1007","author":[{"given":"Susan M.","family":"Smith","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"6_CR1_6","doi-asserted-by":"publisher","first-page":"299","DOI":"10.1002\/tera.1420480403","volume":"48","author":"H. J. Bruyere","year":"1993","unstructured":"1. Bruyere, H. J., and Stith, C. E. (1993) Strain-dependent effect of ethanol on ventricular septal defect frequency in White Leghorn chick embryos. Teratology 48, 299\u2013303.","journal-title":"Teratology"},{"key":"6_CR2_6","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1002\/tera.1420350113","volume":"35","author":"T-T. Fang","year":"1987","unstructured":"2. Fang, T-T., Bruyere, H. J., Kargas, S. A., Nishikawa, T., Takagi, Y., and Gilbert, E. F. (1987) Ethyl alcohol-induced cardiovascular malformations in the chick embryo. Teratology 35, 95\u2013103.","journal-title":"Teratology"},{"key":"6_CR3_6","doi-asserted-by":"publisher","first-page":"1237","DOI":"10.1097\/01.ALC.0000172460.05756.D9","volume":"29","author":"A. Garic- Stankovic","year":"2005","unstructured":"3. Garic-Stankovic, A., Hernandez, M., Chiang, P. J., Armant, D. R., Debelak-Kragtorp, K. A., and Smith, S. M. (2005) Ethanol selectively triggers neural crest apoptosis thru its activation of a pertussis toxin-sensitive G-protein and a phospholipase C\u2013-dependent Ca2+ transient. Alcohol Clin. Exp. Res. 29, 1237\u20131246.","journal-title":"Alcohol Clin. Exp. Res."},{"key":"6_CR4_6","doi-asserted-by":"publisher","first-page":"577","DOI":"10.1002\/(SICI)1097-4547(19960615)44:6<577::AID-JNR8>3.0.CO;2-8","volume":"44","author":"S. Kentroti","year":"1996","unstructured":"4. Kentroti, S., and Vernadakis, A. (1996) Ethanol neurotoxicity in culture: selective loss of cholinergic neurons. J. Neurosci. Res. 44, 577\u2013585.","journal-title":"J. Neurosci. Res."},{"key":"6_CR5_6","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1016\/0741-8329(89)90091-8","volume":"6","author":"L. W. Means","year":"1989","unstructured":"5. Means, L. W., McDaniel, K., and Pennington, S. N. (1989) Embryonic ethanol exposure impairs detour learning in the chick. Alcohol 6, 327\u2013330.","journal-title":"Alcohol"},{"key":"6_CR6_6","doi-asserted-by":"crossref","first-page":"1286","DOI":"10.1111\/j.1530-0277.2002.tb02669.x","volume":"26","author":"R. A. Rovasio","year":"2002","unstructured":"6. Rovasio, R. A., and Battiato, N. L. (2002) Ethanol induces morphological and dynamic changes on in vivo and in vitro neural crest cells. Alcohol Clin. Exp. Res. 26, 1286\u20131298.","journal-title":"Alcohol Clin. Exp. Res."},{"key":"6_CR7_6","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1111\/j.1530-0277.2000.tb04612.x","volume":"24","author":"K. A. Debelak","year":"2000","unstructured":"7. Debelak, K. A., and Smith, S. M. (2000) Avian genetic background modulates the neural crest apoptosis induced by ethanol exposure. Alcohol. Clin. Exp. Res. 24, 307\u2013314.","journal-title":"Alcohol. Clin. Exp. Res."},{"key":"6_CR8_6","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1093\/alcalc\/33.5.457","volume":"33","author":"S. R. Bupp- Becker","year":"1998","unstructured":"8. Bupp-Becker, S. R., and Shibley, I. A., Jr. (1998) Teratogenicity of ethanol in different chicken strains. Alcohol Alcoholism. 33, 457\u2013464.","journal-title":"Alcohol Alcoholism."},{"key":"6_CR9_6","first-page":"31","volume-title":"Methods in Molecular Biology. Vol 135: Developmental Biology Protocols, v.1.","author":"D. K. Darnell","year":"2000","unstructured":"9. Darnell, D. K., and Schoenwolf, G. C. (2000) Culture of avian embryos, in Methods in Molecular Biology. Vol 135: Developmental Biology Protocols, v.1. (Tuan, R. S., and CW Lo, C. W., eds.). Humana Press, Totowa, NJ. pp. 31\u201338."},{"key":"6_CR10_6","first-page":"245","volume-title":"Methods in Molecular Biology. Vol 135: Developmental Biology Protocols, v.1.","author":"M. A. Ros","year":"2000","unstructured":"10. Ros, M. A., Simandl, B. K., Clark, A. W., and Fallon, J. F. (2000) Methods for manipulating the chick limb bud to study gene expression, tissue interactions, and patterning, in Methods in Molecular Biology. Vol 135: Developmental Biology Protocols, v.1. (Tuan, R. S., and CW Lo, C. W., eds.). Humana Press, Totowa, NJ, pp. 245\u2013266."},{"key":"6_CR11_6","doi-asserted-by":"publisher","first-page":"542","DOI":"10.1016\/0003-2697(84)90504-9","volume":"142","author":"G. Eichele","year":"1984","unstructured":"11. Eichele, G., Tickle, C., and Alberts, B. M. (1984) Microcontrolled release of biologically active compounds in chick embryos: beads of 200-microns diameter for the local release of retinoids. Anal. Biochem. 142, 542\u2013555.","journal-title":"Anal. Biochem."},{"key":"6_CR12_6","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1016\/0378-1119(91)90434-D","volume":"108","author":"H. Niwa","year":"1991","unstructured":"12. Niwa, H., Yamamura, K., and Miyazaki, J. (1991) Efficient selection for high-expression transfectants with a novel eukaryotic vector. Gene 108, 193\u2013200.","journal-title":"Gene"},{"key":"6_CR13_6","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1002\/dvdy.10473","volume":"229","author":"C. E. Krull","year":"2004","unstructured":"13. Krull, C. E. (2004) A primer on using in ovo electroporation to analyze gene expression. Dev. Dyn. 229, 433\u2013439.","journal-title":"Dev. Dyn."},{"key":"6_CR14_6","doi-asserted-by":"crossref","first-page":"2604","DOI":"10.1128\/MCB.13.4.2604","volume":"13","author":"D. M. Fekete","year":"1993","unstructured":"14. Fekete, D. M., and Cepko, C. L. (1993) Replication-competent retroviral vectors encoding alkaline phosphatase reveal spatial restriction of viral gene expression\/transduction in the chick embryo. Mol. Cell Biol. 13, 2604\u20132613.","journal-title":"Mol. Cell Biol."},{"key":"6_CR15_6","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1002\/jmor.1050880104","volume":"88","author":"V. Hamburger","year":"1951","unstructured":"15. Hamburger, V., and Hamilton, H. L. (1951) A series of normal stages in the development of the chick embryo. J. Morphol. 88, 49\u201392.","journal-title":"J. Morphol."},{"key":"6_CR16_6","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1002\/bdra.20202","volume":"76","author":"V. J. Drake","year":"2006","unstructured":"16. Drake, V. J., Koprowski, S. L., Lough, J. W., and Smith, S. M. (2006) The gastrulating chick embryo as a model for evaluating teratogenicity: a comparison of three approaches. Birth Defects Res. A. 76, 66\u201371.","journal-title":"Birth Defects Res. A."},{"key":"6_CR17_6","doi-asserted-by":"publisher","first-page":"515","DOI":"10.1097\/01.ALC.0000056615.34253.A8","volume":"27","author":"K. A. Debelak- Kragtorp","year":"2003","unstructured":"17. Debelak-Kragtorp, K. A., Armant, D. R., and Smith, S. M. (2003) Ethanol-induced cephalic apoptosis requires phospholipase C-dependent intracellular calcium signaling. Alcohol Clin. Exp. Res. 27, 515\u2013523.","journal-title":"Alcohol Clin. Exp. Res."},{"key":"6_CR18_6","doi-asserted-by":"crossref","first-page":"3440","DOI":"10.1016\/S0021-9258(19)83641-4","volume":"260","author":"G. Grynkiewicz","year":"1985","unstructured":"18. Grynkiewicz, G., Poenie, M., and Tsien, R. Y. (1985) A new generation of Ca2+ indicators with greatly improved fluorescence properties. J. Biol. Chem. 260, 3440\u20133450.","journal-title":"J. Biol. Chem."},{"key":"6_CR19_6","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1016\/S0091-679X(08)61114-0","volume":"40","author":"J. P. Y. Kao","year":"1994","unstructured":"19. Kao, J. P. Y. (1994) Practical aspects of measuring [Ca2+] with fluorescent indicators. Meth. Cell Biol. 40, 155\u2013181.","journal-title":"Meth. Cell Biol."}],"container-title":["Methods in Molecular Biology\u2122","Alcohol"],"original-title":[],"link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/978-1-59745-242-7_6.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,4]],"date-time":"2021-09-04T02:41:57Z","timestamp":1630723317000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/978-1-59745-242-7_6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008]]},"ISBN":["9781588299062","9781597452427"],"references-count":19,"URL":"https:\/\/doi.org\/10.1007\/978-1-59745-242-7_6","relation":{"is-part-of":[{"id-type":"doi","id":"https:\/\/doi.org\/10.1007\/978-1-59745-242-7","asserted-by":"object"}]},"ISSN":["1064-3745","1940-6029"],"issn-type":[{"value":"1064-3745","type":"print"},{"value":"1940-6029","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008]]}}}