{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,5]],"date-time":"2024-09-05T11:45:29Z","timestamp":1725536729899},"publisher-location":"Totowa, NJ","reference-count":11,"publisher":"Humana Press","isbn-type":[{"type":"print","value":"9781588299703"},{"type":"electronic","value":"9781597453943"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"DOI":"10.1007\/978-1-59745-394-3_9","type":"book-chapter","created":{"date-parts":[[2009,8,29]],"date-time":"2009-08-29T16:59:38Z","timestamp":1251565178000},"page":"111-124","source":"Crossref","is-referenced-by-count":0,"title":["Preparation and Handling of Hepatitis C Viral Proteins NS3 and NS5B for Structural Studies"],"prefix":"10.1007","author":[{"given":"Stefania Di","family":"Marco","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Carf\u00ed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"9_CR1","doi-asserted-by":"publisher","first-page":"953","DOI":"10.1038\/nature04080","volume":"436","author":"R. Francesco De","year":"2005","unstructured":"De Francesco, R., and Migliaccio, G. (2005). Challenges and successes in developing new therapies for hepatitis C. Nature\n                           436, 953\u2013960.","journal-title":"Nature"},{"key":"9_CR2","doi-asserted-by":"publisher","first-page":"18760","DOI":"10.1074\/jbc.273.30.18760","volume":"273","author":"A. Urbani","year":"1998","unstructured":"Urbani, A., Bazzo, R., Nardi, M. C., Cicero, D. O., De Francesco, R., Steinkuhler, C., et al. (1998). The metal binding site of the hepatitis C virus NS3 protease. A spectroscopic investigation. J. Biol. Chem.\n                           273, 18760\u201318769.","journal-title":"J. Biol. Chem."},{"key":"9_CR3","doi-asserted-by":"publisher","first-page":"7890","DOI":"10.1021\/bi9631475","volume":"36","author":"E. Bianchi","year":"1997","unstructured":"Bianchi, E., Urbani, A., Biasiol, G., Brunetti, M., Pessi, A., De Francesco, R., et al. (1997). Complex formation between the hepatitis C virus serine protease and a synthetic NS4A cofactor peptide. Biochemistry\n                           36, 7890\u20137897.","journal-title":"Biochemistry"},{"key":"9_CR4","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1016\/S0092-8674(00)81351-3","volume":"87","author":"J.L. Kim","year":"1996","unstructured":"Kim, J. L., Morgenstern, K. A., Lin, C., Fox, T., Dwyer, M. D., Landro, J. A., et al. (1996). Crystal structure of the hepatitis C virus NS3 protease domain complexed with a synthetic NS4A cofactor peptide. Cell\n                           87, 343\u2013355.","journal-title":"Cell"},{"key":"9_CR5","doi-asserted-by":"publisher","first-page":"837","DOI":"10.1002\/pro.5560070402","volume":"7","author":"Y. Yan","year":"1998","unstructured":"Yan, Y., Li, Y., Munshi, S., Sardana, V., Cole, J. L., Sardana, M., et al. (1998). Complex of NS3 protease and NS4A peptide of BK strain hepatitis C virus: a 2.2 \u00c5 resolution structure in a hexagonal crystal form. Protein Sci. 7, 837\u2013847.","journal-title":"Protein Sci."},{"key":"9_CR6","doi-asserted-by":"publisher","first-page":"13034","DOI":"10.1073\/pnas.96.23.13034","volume":"96","author":"S. Bressanelli","year":"1999","unstructured":"Bressanelli, S., Tomei, L., Roussel, A., Incitti, I., Vitale, R. L., Mathieu, M., et al. (1999). Crystal structure of the RNA-dependent RNA polymerase of hepatitis C virus. Proc. Natl. Acad. Sci. USA\n                           96, 13034\u201313039.","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"9_CR7","doi-asserted-by":"publisher","first-page":"937","DOI":"10.1038\/13305","volume":"6","author":"C.A. Lesburg","year":"1999","unstructured":"Lesburg, C. A., Cable, M. B., Ferrari, E., Hong, Z., Mannarino, A. F., and Weber, P.C. (1999). Crystal structure of the RNA-dependent RNA polymerase from hepatitis C virus reveals a fully encircled active site. Nat. Struct. Biol.\n                           6, 937\u2013943.","journal-title":"Nat. Struct. Biol."},{"key":"9_CR8","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1016\/S0003-2697(02)00295-6","volume":"309","author":"L. Orsatti","year":"2002","unstructured":"Orsatti, L., Di Marco, S., Volpari, C., Vannini, A., Neddermann, P., and Bonelli, F. (2002). Determination of the stoichiometry of noncovalent complexes using reverse-phase high-performance liquid chromatography coupled with electrospray ion trap mass spectrometry. Anal. Biochem.\n                           309, 11\u201318.","journal-title":"Anal. Biochem."},{"key":"9_CR9","doi-asserted-by":"publisher","first-page":"7152","DOI":"10.1074\/jbc.275.10.7152","volume":"275","author":"S. Marco Di","year":"2000","unstructured":"Di Marco, S., Rizzi, M., Volpari, C., Walsh, M. A., Narjes, F., Colarusso, S., et al. (2000). Inhibition of the hepatitis C virus NS3\/4A protease. The crystal structures of two protease-inhibitor complexes. J. Biol. Chem.\n                           275, 7152\u20137157.","journal-title":"J. Biol. Chem."},{"key":"9_CR10","doi-asserted-by":"publisher","first-page":"6443","DOI":"10.1021\/jm049435d","volume":"47","author":"J.M. Ontoria","year":"2004","unstructured":"Ontoria, J. M., Di Marco, S., Conte, I., Di Francesco, M. E., Gardelli, C., Koch, U., et al. (2004). The design and enzyme-bound crystal structure of indoline based peptidomimetic inhibitors of hepatitis C virus NS3 protease. J. Med. Chem.\n                           47, 6443\u20136446.","journal-title":"J. Med. Chem."},{"key":"9_CR11","doi-asserted-by":"publisher","first-page":"29765","DOI":"10.1074\/jbc.M505423200","volume":"280","author":"S. Marco Di","year":"2005","unstructured":"Di Marco, S., Volpari, C., Tomei, L., Altamura, S., Harper, S., Narjes, F., et al. (2005). Interdomain communication in hepatitis C virus polymerase abolished by small molecule inhibitors bound to a novel allosteric site. J. Biol. Chem.\n                           280, 29765\u201329770.","journal-title":"J. Biol. Chem."}],"container-title":["Methods in Molecular Biology","Hepatitis C: Methods and Protocols"],"original-title":[],"language":"en","deposited":{"date-parts":[[2019,3,4]],"date-time":"2019-03-04T00:51:27Z","timestamp":1551660687000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/978-1-59745-394-3_9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[null]]},"ISBN":["9781588299703","9781597453943"],"references-count":11,"URL":"https:\/\/doi.org\/10.1007\/978-1-59745-394-3_9","relation":{},"ISSN":["1064-3745","1940-6029"],"issn-type":[{"type":"print","value":"1064-3745"},{"type":"electronic","value":"1940-6029"}],"subject":[]}}