{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,10]],"date-time":"2026-11-10T22:58:14Z","timestamp":1794351494231,"version":"4.9.0"},"publisher-location":"Totowa, NJ","reference-count":13,"publisher":"Humana Press","isbn-type":[{"value":"9781588294296","type":"print"},{"value":"9781597454568","type":"electronic"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2007]]},"DOI":"10.1007\/978-1-59745-456-8_5","type":"book-chapter","created":{"date-parts":[[2007,12,2]],"date-time":"2007-12-02T03:48:19Z","timestamp":1196567299000},"page":"65-75","source":"Crossref","is-referenced-by-count":15,"title":["Saturation of the Secretory Pathway by Overexpression of a Hookworm (Necator americanus) Protein (Na-ASP1)"],"prefix":"10.1007","author":[{"given":"Mehmet","family":"Inan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah A.","family":"Fanders","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenhui","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter J.","family":"Hotez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin","family":"Zhan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael M.","family":"Meagher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"5_CR1","doi-asserted-by":"crossref","first-page":"1316","DOI":"10.1128\/MCB.9.3.1316","volume":"9","author":"J. M. Cregg","year":"1989","unstructured":"Cregg, J. M., Madden, K. R., Barringer, K. J., Thill, G. P., and Stillman, C. A. (1989) Functional characterization of the two alcohol oxidase genes from the yeast Pichia pastoris. Mol. Cell Biol.\n                9, 1316\u20131323.","journal-title":"Mol. Cell Biol."},{"key":"5_CR2","first-page":"1","volume":"II","author":"J. M. Cregg","year":"1987","unstructured":"Cregg, J. M. and Madden, K. R. (1987) Development of yeast transformation systems and construction of methanol-utilization-defective mutants of Pichia pastoris by gene disruption. Biological Research on Industrial Yeast II, 1\u201318.","journal-title":"Biological Research on Industrial Yeast"},{"key":"5_CR3","doi-asserted-by":"publisher","first-page":"905","DOI":"10.1038\/nbt0893-905","volume":"11","author":"J. M. Cregg","year":"1993","unstructured":"Cregg, J. M., Vedvick, T. S., and Raschke, W. C. (1993) Recent advances in the expression of foreign genes in Pichia pastoris. Biotechnology (N Y)\n                11, 905\u2013910.","journal-title":"Biotechnology (N Y)"},{"key":"5_CR4","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1002\/yea.320050306","volume":"5","author":"P. Koutz","year":"1989","unstructured":"Koutz, P., Davis, G. R., Stillman, C., Barringer, K., Cregg, J., and Thill, G. (1989) Structural comparison of the Pichia pastoris alcohol oxidase genes. Yeast\n                5, 167\u2013177.","journal-title":"Yeast"},{"key":"5_CR5","doi-asserted-by":"publisher","first-page":"547","DOI":"10.1016\/j.pt.2003.10.002","volume":"19","author":"N. R. Silva de","year":"2003","unstructured":"de Silva, N. R., Brooker, S., Hotez, P. J., Montresor, A., Engels, D., and Savioli, L. (2003) Soil-transmitted helminth infection: updating the global picture. Trends Parasitol. 19, 547\u2013551.","journal-title":"Trends Parasitol"},{"key":"5_CR6","doi-asserted-by":"publisher","first-page":"1245","DOI":"10.1016\/S0020-7519(03)00158-9","volume":"33","author":"P. J. Hotez","year":"2003","unstructured":"Hotez, P. J., Zhan, B., Bethony, J. M., et al. (2003) Progress in the development of a recombinant vaccine for human hookworm disease: the Human Hookworm Vaccine Initiative. Int. J. Parasitol.\n                33, 1245\u20131258.","journal-title":"Int. J. Parasitol."},{"key":"5_CR7","doi-asserted-by":"publisher","first-page":"618","DOI":"10.1016\/S0959-437X(96)80092-X","volume":"6","author":"J. M. Hawdon","year":"1996","unstructured":"Hawdon, J. M. and Hotez, P. J. (1996) Hookworm: developmental biology of the infectious process. Curr. Opin. Genet. Dev.\n                6, 618\u2013623.","journal-title":"Curr. Opin. Genet. Dev."},{"key":"5_CR8","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1016\/S0166-6851(01)00453-4","volume":"120","author":"B. H. Zhan","year":"2002","unstructured":"Zhan, B. H., Hotez, P. J., Wang, Y., and Hawdon, J. M. (2002) A developmentally regulated metalloprotease secreted by host-stimulated Ancylostoma caninum third stage infective larvae is a member of astacin family of proteases. Mol. Biochem. Parasitol.\n                120, 291\u2013296.","journal-title":"Mol. Biochem. Parasitol."},{"key":"5_CR9","doi-asserted-by":"publisher","first-page":"6672","DOI":"10.1074\/jbc.271.12.6672","volume":"271","author":"J. M. Hawdon","year":"1996","unstructured":"Hawdon, J. M., Jones, B. F., Hoffman, D. R., and Hotez, P. J. (1996) Cloning and characterization of Ancylostoma-secreted protein; A novel protein associated with the transition to parasitism by infective hookworm larvae. J. Biol. Chem.\n                271, 6672\u20136678.","journal-title":"J. Biol. Chem."},{"key":"5_CR10","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1016\/S0166-6851(99)00011-0","volume":"99","author":"J. M. Hawdon","year":"1999","unstructured":"Hawdon, J. M., Narasimhan, S., and Hotez, P. J. (1999) Ancylostoma secreted protein 2: cloning and characterization of a second member of a family of nematode secreted proteins from Ancylostoma caninum. Mol. Biochem. Parasitol.\n                99, 149\u2013165.","journal-title":"Mol. Biochem. Parasitol."},{"key":"5_CR11","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1016\/S0166-6851(98)00157-1","volume":"98","author":"B. Zhan","year":"1999","unstructured":"Zhan, B., Hawdon, J., Shan, Q., et al. (1999) Ancylostoma secreted protein 1 (ASP-1) homologues in human hookworms. Mol. Biochem. Parasitol.\n                98, 143\u2013149.","journal-title":"Mol. Biochem. Parasitol."},{"key":"5_CR12","volume-title":"Molecular Cloning; A Laboratory Manual","author":"J. R. Sambrook","year":"2001","unstructured":"Sambrook, J. R., DW. (2001) Molecular Cloning; A Laboratory Manual, Third ed. Cold Spring Harbor, New York, Cold Spring Harbor Laboratory Press.","edition":"Third ed."},{"key":"5_CR13","doi-asserted-by":"publisher","first-page":"503","DOI":"10.1016\/S0022-2836(75)80083-0","volume":"98","author":"E. Southern","year":"1975","unstructured":"Southern, E. (1975) Detection of specific sequences among DNA fragments separated by gel electrophoresis. J. Mol. Biol.\n                98, 503\u2013517.","journal-title":"J. Mol. Biol."}],"container-title":["Methods in Molecular Biology","Pichia Protocols"],"original-title":[],"link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/978-1-59745-456-8_5.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T18:04:31Z","timestamp":1619892271000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/978-1-59745-456-8_5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007]]},"ISBN":["9781588294296","9781597454568"],"references-count":13,"URL":"https:\/\/doi.org\/10.1007\/978-1-59745-456-8_5","relation":{"is-part-of":[{"id-type":"doi","id":"https:\/\/doi.org\/10.1007\/978-1-59745-456-8","asserted-by":"object"}]},"ISSN":["1064-3745","1940-6029"],"issn-type":[{"value":"1064-3745","type":"print"},{"value":"1940-6029","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007]]}}}